Neural dynamics of retrieval suppression in abolishing item-specific cortical pattern of unwanted emotional memories

When reminded of an unpleasant experience, people often try to exclude the unwanted memory from awareness in an effort to forget it, a process known as retrieval suppression. Yet, how fast can individual memories be targeted and controlled, and the neural dynamics in modulating cortical traces of individual memories, remain elusive. Here, using multivariate decoding analyses on time-domain and time-frequency-domain EEGs, we found that retrieval suppression of aversive memories was distinct from retrieval and passive viewing, when given a reminder. Specifically, early elevation of mid-frontal theta power during the first 500 ms distinguished retrieval suppression from passive viewing, suggesting that suppression recruited early active control processes. On an item-level, we could discern activities relating to individual memories during active retrieval-initially, based on perceptual responses to reminders (0-500 ms) and later, via the reinstatement and maintenance of the target aversive scenes (500-3000 ms). Critically, suppressing retrieval significantly weakened (during 420-600 ms) and eventually abolished these item-specific cortical patterns till cue disappeared (1200-3000 ms), suggesting the successful exclusion of the unwelcome memory from awareness. Suppression of item-specific cortical patterns bore behavioral consequences in predicting subsequent episodic forgetting. These findings provide unique insight into the neural dynamics underlying the control of unwelcome memories: upon perceiving an unwelcome reminder, people rapidly deploy inhibitory control to truncate retrieval within 500 ms, which likely terminate the reminder-to-memory conversion at around 500 ms that would ordinarily arise through hippocampal pattern completion. We concluded that both rapid and sustained control are critical in abolishing cortical patterns of individual memories, limiting unwelcome awareness, and precipitating later forgetting.

Nursing a horse with strangles

Strangles can be an extremely debilitating and unpleasant experience for an infected horse. Diligent nursing care is important as the disease runs its course, to maximise the chances of a full and straightforward recovery. Veterinary nurses can play a critical role in strangles outbreaks by ensuring horses are in a comfortable environment within quarantine, are encouraged to eat and drink, benefit from careful abscess management and are monitored closely. Nurses also provide essential support for vets during procedures such as guttural pouch endoscopy, as well as helping to maintain strict biosecurity protocols to prevent further spread of disease.

Postoperative Drip-Infusion of Remifentanil Reduces Postoperative Pain—A Retrospective Observative Study

Development of remifentanil-induced hyperalgesia (RIH) postoperatively is an unpleasant experience that requires further treatment. This study assessed the effects of gradual withdrawal combined with drip infusion of remifentanil on postoperative pain and the requirement for rescue analgesics. A total of 559 patients receiving total intravenous anesthesia with propofol and remifentanil were enrolled. All patients either underwent gradual withdrawal of remifentanil (GWR) or gradual withdrawal combined with drip infusion (GWDR) with a dose of 1 mcg·kg−1 for 30 min after extubation. The numeric rating scale (NRS) and the requirement of rescue analgesics were assessed. The requirement for rescue analgesics was significantly lower in the GWDR group than in the GWR group (13.2% vs. 35.7%; p < 0.001). At the post-anesthetic care unit (PACU), patients in the GWDR group had a lower NRS pain score (p < 0.001). In addition, in the postoperative 2nd hour, patients in the GWDR group had a significantly lower NRS than the GWR group (beta, −0.31; p = 0.003). No remifentanil-related adverse effects were observed. We found that gradual withdrawal combined with drip infusion of remifentanil required less rescue analgesics and reduced pain scores. The new way of remifentanil administration may be effective to prevent RIH.

Kesantunan Interogatif Bahasa Jawa dalam Menanyakan Petunjuk Arah

This research is motivated by someone's unpleasant experience when asking directions in Javanese (BJ). Because it is considered impolite, the answer that person gets is wrong and unpleasant. Therefore, this study seeks to formulate BJ's verbal and nonverbal interrogative politeness in asking directions. The data of this research are in the form of BJ conversations in asking directions. The data were obtained through FGD, interview and experimental. The conversation data is then analyzed deconstructively to find markers of politeness. The conclusion from this research is that the formulation of politeness to ask directions verbally is influenced by a) components, functions, and speech codes, b) short length of speech, c) speech sequence, d) intonation, and e) use of expressions marking politeness. This verbal politeness needs to be supported by nonverbal politeness, namely not driving a vehicle, removing all the attributes that cover the face, and not puffing out the body. Keywords: Javanese language, politeness, interrogative, asking directions

Perceptions of the Post First-Lockdown Era in the Current Covid-19 Pandemic: Quantitative and Qualitative Survey of the French Population

Introduction: A pandemic with the severity of COVID-19 affects people's lives physically, as well as their daily routines, views of the world, and emotional balance. Lockdown is often an unpleasant experience due to a separation from loved ones, loss of freedom, and uncertainty over the disease status. To adjust, individuals and groups have had to adapt their perceptions of the event to the current scenario. This study aims to describe the perceptions of confined people on the changes occurring in their lives in the aftermath of the COVID-19 lockdown.Methods: A total of 1,534 individuals (26.6% men; 73.4% women; mean age 41.6) responded to the questionnaire comprising 19 closed and five open-ended questions about the changes they anticipated in their lives in the immediate post-confinement era.Results: Two definite groups appeared in the results: those who lived the confinement pleasantly, and those for which it was painful. They differ according to their confinement conditions and perceived degree of exposure to the virus. There seems to be a link for those who had a pleasant experience to a lower perceived exposure to the virus and less burdensome confinement conditions (young children, surface area, etc.). Lockdown conditions seem to influence the respondents' perceptions: a pleasant experience is associated with a vision of the society's evolution at large, and the care about its economic and professional progress; a painful one is associated more with focusing on the immediate needs of social support and personal well-being.Discussion: Emotional experience during lockdown impacts the perception of its aftermath, with hope and anxiety becoming two ways of coping with uncertainty.

TRANSCARPATHIAN EDUCATION THROUGH THE PRISM OF DIALECT ATTITUDE

Most of the pupils who go to school speak the language version they have learned at home and only during the teaching process acquire the standard version of the spoken language. That is why it is extremely important that any negative, unpleasant experience should not be connected to the primary language version, as the only basis, building onwhich, mother tongue teaching can be effective. In our study, based on the data from a repeated questionnaire collection, we would like to illustrate what do the teachers of the Transcarpathian secondary schools with the Hungarian language of instruction think about the non-standard versions and theirs speakers. In 2008, 150 teachers responded to the questions about a language and dialect attitude, and in 2018, the same questionnaire was completed by 100 colleagues online or on paper basis. In the study, we used the SPSS statistical processing program, so it turns out whether there has been a significant change in the perception of dialects in the last 10 years in the studied community. After all, the teaching of Hungarian as a mother tongue was reformed during this period, and the curriculum also gave priority to the issue of mother tongue’ version and communication competence. Based on the partial results of the repeated study, we can state that in the past 10 years the opinion of Transcarpathian teachers of secondary schools with the Hungarian language of instruction has changed in a positive direction.There was a higher proportion of responses suggesting an additive approach mediated by the formal curriculum than in 2008. Nevertheless, the explanatory answers received in addition to the more positive statistics still show a trace of the previous approach: the linguistic and dialectal consciousness of the majority of the respondents is far from definite and confident.There are a number of stereotypes in seemingly benign but rather forgiving writings that take longer to undress.However, it is clear that the reform of mother tongue education has an impact, even a positive one. In order to be even more effective, the mother-tongue education in Transcarpathia must follow this way. Therefore, it is important that teachers who teach in both Ukrainian and minority languages show a definite and objective attitude towards their pupils in addition to/despite the changing mother tongue curricula and inconsistent textbooks that do not meet local needs.

Personal perspectives: having the time to observe the patient

Being a medically qualified patient can be an unpleasant experience for a person who is used to making decisions. For the most part, this applies to the vast majority of doctors and other healthcare professionals. Becoming passive and surrendering the decision-making process to others is alien to the medical culture we were taught. However, when as a hospitalised medically qualified patient, one sees fellow patients in difficulty, or deteriorating clinically, unnoticed by medical staff, the question of whether it is ethical to intervene arises. I report my views on this as a largely passive, but still actively thinking patient.

Sikap Perawat Terhadap Pasien Menjelang Ajal Dan Sikap Terhadap Kematian

Merawat pasien menjelang ajal merupakan pengalaman yang kurang menyenangkan bagi perawat karena bisa menimbulkan rasa takut, cemas, sedih dan frustasi. Tujuan dari penelitian ini adalah mengetahui hubungan antara sikap perawat pasien menjelang ajal dan sikap terhadap kematian. Metode yang digunakan dalam penelitian ini adalah deskriptif korelasi dengan menggunakan tehnik convinence sampling kepada 95 perawat yang bekerja di Rumah Sakit Advent Bandung. Pengumpulan data dilakukan pada bulan Oktober - November 2019. Untuk mengukur sikap perawat terhadap pasien menjelang ajal digunakan kuesioner Frommelt’s Attitude Toward Care of the Dying (FATCOD) scale. Sedangkan untuk mengukur sikap perawat terhadap kematian digunakan kuesioner Death Attittudes Profile-Revised (DAP-R). Hasil penelitian ini menunjukkan bahwa sebagian besar perawat memiliki sikap yang negatif terhadap pasien menjelang ajal (dying attitude) yaitu 83% dan 81.1% menunjukkan sikap yang negatif terhadap kematian (death attitude). Hasil uji-t dan uji-F menunjukkan bahwa unit kerja dan pelatihan paliatif mempunyai hubungan yang positif terhadap perawatan menjelang ajal dengan nilai sig< 0.05. Oleh karena itu penulis menyarankan agar perawat diberikan pelatihan tentang perawatan paliatif agar dapat meningkatkan sikap yang positif dalam merawat pasien menjelang ajal dan sikap terhadap kematian. Kata kunci: kematian; menjelang ajal; sikap perawatNURSE’S BEHAVIOR TOWARD DEATH AND DYING PATIENT ABSTRACT Caring for a dying patient is an unpleasant experience because nurses can feel frightened, anxiety, sadness, and frustration. The purpose of this study was to determine the correlation between nurse’s behavior towards death and dying patient. Data collection was conducted from October - November 2019 to 95 nurses at Adven Hospital of Bandung using a convenience sampling technique and descriptive correlation method using Frommelt's Attitude toward Care of the Dying (FATCOD) scale and Death Attitudes Profile-Revised (DAP-R) questionnaire. The results of this study indicate that the majority (87.4 %) of nurses have a negative dying attitude, and 81.1 % of nurses have a negative death attitude. F-test and t-test show that the work unit and palliative training have a significant correlation (sig <0.05) to nurses’ dying attitude. Therefore the authors suggest that nurses need to take palliative training to enhance nurses' positive dying attitudes and death attitudes. Keyword: death; dying; nurse attitude

Experience of sexual harassment in patients with mental disorders

Sexual harassment is a form of an unpleasant experience making a person uncomfortable. It has physical or psychological impacts. 163-403-2-ED. The research aimed to find out the experience of sexual harassment that causes behavioral changes in patients with mental illness in Banyumas Regional Hospital.This was quantitative descriptive research. There were 32 people taken as the research sample using purposive sampling technique. The data resulted in the distribution of each variable in percentage, classified in the Slovin formula. A questionnaire from the Sexual Harassment Inventory (SHI) was also employed. The average age of the patients who had experienced sexual harassment was 31.53 years, and it happenned when they were 19.56 years. Most of them were male (68.8%), had primary school education (40.6%), and were already employed (53, 1%). The sexual harassment was in the form of verbal and non-verbal abuse (59.4%). It mostly occurred 1-2x (40.6%) in patients with a history of mental care 1-3x (40.6%). The perpetrators were mostly female (59.4%) and non-family members (87.5%). Most of the patients experienced severe sexual harassment (84.4%), causing annoyance (46.9%).In conclusion sexual harassment can be a factor in mental illness.