Development of Wrist Interface Based on Fully Actuated Coaxial Spherical Parallel Mechanism for Force Interaction

To develop a wrist robotic exoskeleton-type interface (REI) for force interaction, it should have a suitable range of motion similar to human wrist activities of daily living, large torque output performance, and low moving parts inertia for dynamic motion response to cover the human behavior frequency. In this paper, a wrist REI based on a fully actuated coaxial spherical parallel mechanism (CSPM) is proposed to satisfy the aforementioned features. The fully actuated CSPM-based wrist REI (FC-WREI) has the characteristics of pure rotation similar to the human wrist, high torque output by parallel torque synthesis, and low moving parts inertia due to the base arrangement of the actuators. Due to the mechanical advantages and design optimization, the FC-WREI maximally provides torque as much as 56.49–130.43% of the maximum isometric torque of the human wrist, while providing a consistent range of motion to the human wrist without interference problem. Moreover, it is confirmed that the inertia of the FC-WREI is up to 5.35 times lower than similar devices. These advantages of the FC-WREI mean that the device is applicable to various fields of REIs for force interaction.

Predicting Caregiver Reactions to Challenging Behaviors in the Context of Dementia

Challenging behaviors exhibited by people living with dementia have been associated with a variety of negative outcomes including greater caregiver burden, nursing home placement, and lower quality of life. Although there has been considerable research on psychological and behavioral changes in dementia, little research has explored family caregiver reactions to these changes and what caregiver characteristics are associated with stronger emotional reactions. This research examined the relationship between established indicators of caregiver mental health (depression, burden, grief, well-being) and caregiver reaction scores on the Revised Memory and Behavior Problems Checklist (RMBPC). The sample consisted of 76 family caregivers for people living with dementia, aged 25 to 93, who participated in a study on caregiver burden and grief. Multiple regression was used to predict RMBPC caregiver reaction scores from the Zarit Burden Inventory, Geriatric Depression Scale, Ryff Psychological Well-Being Scale, and Anticipatory Grief Scale while controlling for RMBPC total behavior frequency scores. RMBPC total behavior frequency scores and Zarit Burden Inventory were significant predictors of caregiver reaction scores (F(2,74) = 87.559, p < .001, R2 = .703). More frequent, challenging behaviors were associated with more distressing reactions and higher caregiver burden also predicted more distress on the RMBPC reaction scores. Psychological well-being was associated with lower reactions at the bivariate level but was not significant in the full regression model. Future research is needed to better understand these relationships and implement this knowledge to benefit family caregivers.

378. Descriptive Analysis of SARS-CoV-2 Infections Among Health System and University Employees

Background We aimed to describe SARS-CoV-2 (COVID-19) infections among employees in a large, academic institution. Table 1. COVID-19 Attribution Definitions Table 2. Description of 3,140 COVID 19 Infections in Employees from 3/2020 to 4/2021 Methods We prospectively tracked and traced COVID-19 infections among employees across our health system and university. Each employee with a confirmed positive test and 3 presumed positive cases were interviewed with a standard contact tracing template that included descriptive variables such as high-risk behaviors and contacts, dates worked while infectious, and initial symptoms. Using this information, the most likely location of infection acquisition was adjudicated (Table 1). We compared behavior frequency between community and unknown, likely community and community and unknown cases using descriptive statistics. Table 3. Risk Factors for Community, Likely Community, and Unknown Cases Number of SARS-CoV-2 cases among employees between 3/2020 and 4/2021 by month and stratified according to clinical employee working in the healthcare system, non-clinical employee employed by the healthcare system, and university employee Results From 3/2020 to 4/2021 we identified 3,140 COVID-19 infections in 3,119 employees out of a total of 34,562 employees (9.0%) (Figure 1). Of those 3,119 employees 1,685 (54.0%) were clinical employees working in the health system, 916 (29.4%) were non-clinical employees working in the health system, and 518 (16.6%) were university employees. Descriptive characteristics for the COVID-19 infections and adjudications are outlined in Table 2. Severe disease among employees was significantly less frequent compared to patients in the health system (15.3% vs 2.2%, p< 0.01). The frequency of travel within 14 days, masked gatherings and unmasked gatherings/activities was not significantly different between the community and unknown, likely community groups or the community and unknown groups (Table 3). Conclusion The majority of COVID-19 infections were linked to acquisition in the community, and few were attributed to workplace exposures. Employees with unknown sources of COVID-19 participated in higher-risk activities at approximately the same frequency as employees with community sources of COVID-19. The most frequently reported initial symptoms were mild and non-specific and rarely included fever. Despite a comprehensive testing and benefit program, a large proportion of COVID-positive employees worked with symptoms, highlighting ongoing challenges with presenteeism in healthcare. Disclosures Rebekah W. Moehring, MD, MPH, UpToDate, Inc. (Other Financial or Material Support, Author Royalties)

COVID-19 Pandemic Analysis

The development of coronavirus disease (COVID-19) deaths in selected nations and states is compared to the result of calculations using a conventional SEIR model of pandemic development. The model is based on the infection multiplier, R0, defined as the number of people infected by each infectious person. The infection rate increases exponentially when R0 >1.0; it remains constant at R0 = 1.0 and decreases for R0 < 1.0. R0 is determined by population behavior (frequency and proximity of interactions) and the ease by which a victim is infected by an infectious person (virus' virulence). It is reduced by herd immunity when a large fraction of the population acquires immunity by vaccination or by recovering from infection. The daily death rates in the U.S. and northern Europe exhibited peaks in April/May 2020 and Dec. 2020/Jan. 2021 with more a modest rate during the summer of 2020 and a gradually decreasing rate since Jan. 2021. The model produces this type of oscillatory response if it assumes that the population's R0 responds to information reported about the pandemic, but with a delay between infections and resulting behavioral adjustments. Oscillatory behavior is typical of a control loop with delay in its feedback. The analysis concludes that: Given the history of R0 the model predicts the development of pandemic deaths. However, since R0 is determined by the population's behavior, control of the pandemic in democracies depends primarily on preparation and the persuasive power of political and scientific authorities. Data for S. Korea and New Zealand demonstrate the effectiveness of such methods. For each death in the U.S. about 169 persons were infected, but fewer than half of them were identified as cases. The pandemic was prolonged in the U.S. because the population chose to keep R0 near 1.0 by relaxing restrictions once the death rate subsided. Initial values of R0 as high as 5.0 were observed, leading to infections doubling about every 2 days. If unabated, the resulting exponential growth increases the infected population by a factor of about 5000 before the death from the first infections is recorded. Arrival from Italy probably initiated the pandemic in the eastern U.S., but, by the time the first death was recorded the number of domestic infections exceeded by far those that were imported. Import restrictions beyond this point are ineffective except in delaying the arrival of more virulent mutations. If no social restrictions had been adopted, approximately 1.6 million deaths would have resulted in the U.S. The vaccine, although developed and deployed at record speed, was too late to ameliorate this result. A third peak in death rate in Sept. 2021 may be prevented if more than 80% of the population is vaccinated.

Modeling the System of Beliefs That Affect Driving Under the Influence of Cannabis and Alcohol in Washington State

Washington state has observed increases in polydrug use in fatal crashes, primarily involving the combination of cannabis and alcohol. The purpose of this article is to explore the belief system associated with driving under the influence of cannabis and alcohol (DUICA) in Washington state using structural equation modeling (SEM). A convenience sample ( n = 737) of surveys collected from adults in Washington state was analyzed using SEM to reveal the latent structure of the belief system associated with DUICA. The results of this analysis indicated that the reported DUICA behavior (frequency) was predicted by intention and willingness. Willingness also predicted intention. Intention and willingness were predicted by positive attitudes toward DUICA, as well as normative perceptions that it was acceptable to important people and common behavior for most people. These components were themselves predicted by corresponding beliefs (behavioral beliefs, normative beliefs, and control beliefs). Finally, these beliefs were also influenced by the values that were most important to the respondents. Based on these results, it is reasonable to speculate that strategies to change these beliefs may also reduce DUICA behavior and associated fatal crashes.

threatening a teacher

Background: Threatening teachers increases teacher stress and impairs emotional well-being. There are many reasons for violence against teachers. There are communication errors and conceptual differences in applying the rules that emphasizes corporal punishment rather than persuasive punishment. Also, it is related to a parent complaint that expresses Parents' belief in the education their child received in school is getting weaker. In addition to the incompetence that teachers must implement, like personal, social and professional aspects that make students offend teachers. Threatening someone considered as physical aggression. Aggression is any behavior intended to harm another person that wishes to avoid such harm High rates of aggression were reported recently in Iraq, especially after wars. Some studies have shown that students, whose friends engage in negative activities such as dropping out of school and have lower academic performance, may engage in aggressive activities toward teachers and/or other students. Objectives: To estimate the prevalence of students’ aggressive act towards teachers. Methodology: A cross-sectional study was carried out in Al-Sadr city in Baghdad. A total of 720 adolescent secondary schools students from both genders were included in the study. They were selected by multistage random sampling. Their age was ranged from 13-21 years. Data was collected from 1st of February 2019 to 30 of April 2019 through a self-reported questionnaire (Aggression-Problem Behavior Frequency Scale). Results: The mean age of participants was 16.2±2.04 years. Of all participants, 84.3% were assessed to be aggressive. There was a significant difference between aggressive act (threatening a teacher) and sex, school type, grade, history of absence from school and employed mother,(P=0.038, 0.009, 0.0001,p= 0.02 and p=0.018, respectively). 10% of male threatening a teacher. Conclusion: A high prevalence of aggression among students was found. Threatening a teacher was dominant among male students, intermediate schools, 4th grade, students with history of absence from school, and not employed mother.

Depressive Symptoms and Healthy Behavior Frequency in Polish Postmenopausal Women from Urban and Rural Areas

The objective of this study was to determine whether the severity of depressive symptoms was linked to healthy behaviors in Polish postmenopausal women and whether the strength of the link differed between women living in urban versus rural settings. The study was conducted in 2018 in the Lublin region of Poland and included 396 postmenopausal women (239 living in rural areas and 157 in urban areas). The severity of depressive symptoms was evaluated by the Beck Depression Inventory (BDI) and the frequency of healthy behaviors was assessed using the Inventory of Healthy Behaviors. Postmenopausal women living in rural areas underwent menopause significantly earlier, were more often widowed, more often obese, more often less educated, and less likely to have never married when compared to those living in urban areas. Importantly, rural postmenopausal women endorsed more depressive symptoms (p = 0.049). There was a negative correlation between the severity of depressive symptoms and age in urban postmenopausal women (r = −0.174, p = 0.029), but this was not evident in rural women (r = −0.034, p = 0.600). The frequency of healthy behaviors was significantly lower in rural postmenopausal women, especially with respect to nutritional habits. A positive correlation was found between the frequency of healthy behaviors and the level of education in both sets of women (p = 0.034 and p = 0.045, respectively). To summarize, we found a significant link between healthy behaviors and depressive symptoms in postmenopausal women. We also found that this link was more evident in rural than in urban women.

A Study of demographic factors of online shoppers in Lucknow, U.P, India

Online buying and shopping is a rising concept in the area of E-Commerce and is absolutely departing to be the future of Online shopping in Indian market. Majority of the firms are operating their online websites to promote and sell their products as well as services through online medium/website. In present scenario online shopping is very much used by Indians, its development is enormous in Indian online market. India is a large customer market place but still lacking as compared to global market. The future of development of online shopping has forwarded the plan of performing a study on online shopping market in India. This research work presents Qualitative and Quantitative research for Indian online market to study the impact and role of Demographic factors of customers in online shopping. The parameters, which we are considering like satisfaction of customers in online shopping market, future purchasing behavior, frequency of transactions in online shopping, total numbers of items bought, and total spending in online shopping. These data for the analysis was collected through Questionnaires on a sample of 125 respondents from Lucknow City. The results of this research indicates that online shopping market in India is affected by several Demographic factors such as marital status, age, family size, gender and income of the respondents. The results and analysis of this research may be further extended by the researchers for forwarding the future studies in this area.

Indicators of Postoperative Pain in Syrian Hamsters (Mesocricetus auratus)

Despite the use of Syrian hamsters (Mesocricetus auratus) in research, little is known about the evaluation of pain in this species. This study investigated whether the frequency of certain behaviors, a grimace scale, the treat-take-test proxy indicator, body weight, water consumption, and coat appearance could be monitored as signs of postoperative pain in hamsters in a research setting. Animals underwent no manipulation, anesthesia only or laparotomy under anesthesia. An ethogram was constructed and used to determine the frequencies of pain, active and passive behaviors by in-person and remote videorecording observation methods. The Syrian Hamster Grimace Scale (SHGS) was developed for evaluation of facial expressions before and after the surgery. The treat-take-test assessed whether surgery would affect the animals’ motivation to take a high-value food item from a handler. The hypothesis was that behavior frequency, grimace scale, treat-take-test score, body weight, water consumption, and coat appearance would change from baseline in the surgery group but not in the no-intervention and anesthesia-only groups. At several time points, pain and passive behaviors were higher than during baseline in the surgery group but not the anesthesia-only and no-intervention groups. The SHGS score increased from baseline scores in 3 of the 9 animals studied after surgery. The frequency of pain behaviors and SHGS scores were highly specific but poorly sensitive tools to identify animals with pain. Behaviors in the pain category were exhibited by chiefly, but not solely, animals that underwent the laparotomy. Also, many animals that underwent laparotomy did not show behaviors in the pain category. Treat-take-test scores, body weight, water consumption, and coat appearance did not change from baseline in any of the 3 groups. Overall, the methods we tested for identifying Syrian hamsters experiencing postoperative pain were not effective. More research is needed regarding clinically relevant strategies to assess pain in Syrian hamsters.

АНАЛИЗ НЕКОТОРЫХ СОЦИАЛЬНЫХ ФАКТОРОВ, ВЛИЯЮЩИХ НА ПОВЕДЕНИЕ ПОТРЕБИТЕЛЯ ФАРМАЦЕВТИЧЕСКИХ ОРГАНИЗАЦИЙ / ANALYSIS OF SOME SOCIAL FACTORS AFFECTING CONSUMER BEHAVIOR OF PHARMACEUTICAL ORGANIZATIONS

В результате исследования мы определили влияние различных факторов на поведение потребителей лекарств и парафармацевтических товаров. Среди них были выделены социально-демографические, социально-психологические и товарные оценочные факторы. Как социально-психологические оценочные факторы при выборе потребителем лекарств нами были рассмотрены мотивация; потребительский этноцентризм; престижность; потребительская враждебность. В ходе проведенного анализа характеризовано влияние функциональных и приданных характеристик лекарств на принятие решения о покупке. Исследованы социальные факторы среды мелкорозничной фармацевтической организации (аптеки) и доказано их влияние на потребительское поведение на месте продажи. Установлена прямая взаимосвязь между количеством стандартов обслуживания, удовлетворенностью персонала и частотой посещения аптеки потребителями. / In this article the influence of various factors on consumer’s behavior of pharmaceutical products is defined. Among such factors socially-demographic, socially-psychological and commodity estimated factors are allocated and described. Influence of the functional and structure characteristics of medical products on decision-making about purchase is separately characterized. Social factors of the environment of the pharmaceutical organization are investigated and their influence on consumer behavior is statistically proved. The lowest level of satisfaction is observed among pharmacists who are constantly busy serving consumers; the average degree of satisfaction – among employees who do not have contact with end users and the greatest satisfaction with work was found among the administrative and management personnel. The performed diagnostics of the social environment of the pharmacy made it possible to identify the main factors for the subsequent assessment of their influence on consumer behavior. The analysis of the dependence of consumer behavior (frequency of visits) on their social environment was carried out, which showed the presence of a direct relationship between the number of service standards, as well as the satisfaction of pharmacists. It was found that the greater the number of service standards, the greater the satisfaction of the personnel with labor motivation. And the greater the satisfaction of pharmaceutical workers with the quality of work, the higher the frequency of visits by consumers to the surveyed pharmacies.