IoT comprises billions of devices that can sense, communicate, compute, and potentially actuate. The data generated by the IoTs are valuable and have the potential to drive innovative and novel applications. IoT allows people and things to be connected anytime, anyplace and to anyone with the internet using tiny sensor. One of the best advantages of the IoT is the increasing number of low-cost sensors available along with its functionalities. A few standard sensors include linear accelerator, compass, light sensors, camera, and microphone, moisture, location, heart rate, and heart rate variability. The trend is multi-sensor platforms that incorporate several sensing elements. In such environment, discovering, identifying, connecting, and configuring sensor hardware are critical issues. The cloud-based IoT platforms can retrieve data from sensors IoT is an inter-disciplinary technology, encompassing multiple areas such as RTS, embedded systems. This chapter detailed investigation and presents highly innovative and revolutionary ideas in healthcare application are available.