The Role of the IGF-1 and its Partners in Central and Peripheral Metabolism: Considerations for Extending Healthy Life Span

2009 ◽  
pp. 143-153
Author(s):  
Nir Barzilai ◽  
Derek M. Huffman ◽  
Pinchas Cohen ◽  
Radhika H. Muzumdar
Keyword(s):  
Life Span ◽  
Healthy Life ◽  
Peripheral Metabolism

scholarly journals ROLE OF AHARA IN GRACEFUL AGING

2018 ◽  
Vol 6 (06) ◽  
Author(s):  
Sonali Shukla
Keyword(s):  
Mental Health ◽  
Developing Countries ◽  
Life Span ◽  
Old Age ◽  
Leafy Vegetables ◽  
Healthy Life ◽  
Green Leafy Vegetables ◽  
Old Age Depression

Aging has become an important issue in developing countries. Ageing is an inevitable process. Although one cannot escape from this reality but one can be able to age gracefully. Ayurveda and its principles can play an important role in to relieve the hardships of old age. As Ahara, Nidra and Bramhacharya are three pillars of Life, Certain Dietary rules and sleeping pattern can increase healthy life span and prevent the development  of diseases. The key to balance Vatadosha in old age is regularity,  rest and warmth One should  pay equal attention to physical as well as mental health. Depression is also a very common problem in old age. Depression can hamper digestive one should adopt capacity of an individual. Sattvik ahara, fresh and hot food, green leafy vegetables & seasonal fruit, proper nidra as part and parcel of old age. Rasayan chikitsa, Sattvavajay chikitsa, yoga, can add years to the life of old persons.

GERMAS ( Gerakan Masyarakat Hidup Sehat) Di Desa Rambah Hilir

2020 ◽  
Vol 3 (1) ◽  
pp. 100
Author(s):  
Elvira Junita ◽  
Yuli Handayani ◽  
Lufita Nur Alfiah
Keyword(s):  
Fruits And Vegetables ◽  
Healthy Lifestyle ◽  
Health Centre ◽  
Health Check ◽  
Community Partnership ◽  
Health It ◽  
Community Members ◽  
Healthy Life ◽  
Partnership Program

AbstrakPermasalahan kesehatan yang timbul saat ini merupakan akibat dari perilaku hidup yang tidak sehat. Gaya hidup yang kurang baik mengakibatkan tingginya angka kejadian Penyakit Tidak Menular, Di Desa Rambah Hilir kunjungan penderita hipertensi dan diabetes di Puskesmas Rambah Hilir I di tahun 2018 ini sampai bulan Juni 66 kasus Hipertensi 27 Kasus Diabetes. Gerakan Masyarakat Hidup Sehat (GERMAS) merupakan progam Pemerintah untuk mengajak masyarakat hidup sehat dengan focus pada 3 kegiatan utama yaitu melakukan aktifitas fisik, makan buah sayur dan cek kesehatan secara rutin minimal enam bulan sekali.Dalam Program Kemitraan Masyarakat ini upaya yang dilakukan adalah meningkatkan gaya hidup sehat yakni meningkatnya aktifitas fisik yang dilakukan dengan melaksanakan kegiatan rutin senam bersama setiap hari minggu dan meningkatkan konsumsi buah dan sayur dengan memanfaatkan lahan perkarangan rumah warga dengan menanam buah dan sayur dihalaman rumah untuk memenuhi kebutuhan konsumsi buah dan sayur. Upaya Peningkatan peran masyarakat dalam memeriksakan kesehatannya dengan mendirikan posko kesehatan untuk memudahkan masyarakat dalam memeriksa kesehatannya. Luaran yang telah dicapai adalah Adanya kegiatan senam rutin, meningkatnya konsumsi buah dan sayur dengan Adanya tanaman buah dan sayur disetiap rumah warga, makan buah dan sayur bersama setiap hari minggu, Adanya pemeriksaan kesehatan secara berkala.Abstract.Health problems that currently emergeare resulted from unhealthy living behaviours. A bad lifestyle causes an increase innon-communicable diseases cases. According to patient visit data until June 2018 at the community health centre (Puskesmas) Rambah Hilir I, Rambah Hilir Village, Rokan Hulu, Riau, it shows that there were 66 cases of hypertension and 27 cases of diabetes.The Healthy Life Society Movement (GERMAS) is a government program to encourage people to live a healthy lifestyle focusing on 3 main activities namely physical activities, eating vegetables, together with regular health check-upsat least once every 6 months. This community partnership program attempts to enhance the healthy lifestyle by intensifying physical activitiesthrough a routine collective exercise on every Sunday and increasing fruits and vegetables consumption. The community members’ yards are used as land to grow fruits and vegetables for meeting the community’s needs. Regarding the effort to improve the role of the community members to check their health, it was carried out by establishing a health post to facilitate them in checking-up their health. Outputs that have been achieved are the routine exercise; an increase in fruits and vegetables consumptionasthere are fruit and vegetable plants in every resident's houses; eating fruits and vegetables collectively on every Sunday; as well as regular health check-ups.

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

The Role of Hadith in the Construction of Healthy Life Style in Students

2019 ◽  
Vol 9 (10) ◽  
pp. p9459
Author(s):  
Haydarova Pardaxol Bobaqulovna ◽  
Abdullayeva Dilfuza Rixsixodjayevna ◽  
Raimov Sodiq Sobirovich
Keyword(s):  
Life Style ◽  
Healthy Life ◽  
Healthy Life Style

scholarly journals Nutrition research to affect food and a healthy life span

2013 ◽  
Vol 98 (2) ◽  
pp. 620-625 ◽  
Author(s):  
Sarah D. Ohlhorst ◽  
Robert Russell ◽  
Dennis Bier ◽  
David M. Klurfeld ◽  
Zhaoping Li ◽  
...  
Keyword(s):  
Life Span ◽  
Healthy Life ◽  
Nutrition Research

scholarly journals Loss of Ubp3 increases silencing, decreases unequal recombination in rDNA, and shortens the replicative life span in Saccharomyces cerevisiae

2014 ◽  
Vol 25 (12) ◽  
pp. 1916-1924 ◽  
Author(s):  
David Öling ◽  
Rehan Masoom ◽  
Kristian Kvint
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Rna Polymerase ◽  
Life Span ◽  
Rna Polymerase Ii ◽  
Ribosomal Dna ◽  
Genetic Evidence ◽  
Wild Type ◽  
Replicative Life Span ◽  
Unequal Recombination

Ubp3 is a conserved ubiquitin protease that acts as an antisilencing factor in MAT and telomeric regions. Here we show that ubp3∆ mutants also display increased silencing in ribosomal DNA (rDNA). Consistent with this, RNA polymerase II occupancy is lower in cells lacking Ubp3 than in wild-type cells in all heterochromatic regions. Moreover, in a ubp3∆ mutant, unequal recombination in rDNA is highly suppressed. We present genetic evidence that this effect on rDNA recombination, but not silencing, is entirely dependent on the silencing factor Sir2. Further, ubp3∆ sir2∆ mutants age prematurely at the same rate as sir2∆ mutants. Thus our data suggest that recombination negatively influences replicative life span more so than silencing. However, in ubp3∆ mutants, recombination is not a prerequisite for aging, since cells lacking Ubp3 have a shorter life span than isogenic wild-type cells. We discuss the data in view of different models on how silencing and unequal recombination affect replicative life span and the role of Ubp3 in these processes.

Long life span of tolerant T cells and the role of antigen in maintenance of peripheral tolerance

1995 ◽  
Vol 7 (2) ◽  
pp. 331-336 ◽  
Author(s):  
Judith Alferink ◽  
Birgit Schittek ◽  
Günter Schönrich ◽  
Günter J. Hämmerling ◽  
Bernd Arnold
Keyword(s):  
T Cells ◽  
Life Span ◽  
Peripheral Tolerance ◽  
Long Life

scholarly journals Motivation as a Mediator of the Relation Between Cognitive Reserve and Cognitive Performance

2018 ◽  
Vol 75 (6) ◽  
pp. 1199-1205
Author(s):  
Fanny Vallet ◽  
Nathalie Mella ◽  
Andreas Ihle ◽  
Marine Beaudoin ◽  
Delphine Fagot ◽  
...  
Keyword(s):  
Intrinsic Motivation ◽  
Life Span ◽  
Cognitive Performance ◽  
Cognitive Processes ◽  
Cognitive Aging ◽  
Cognitive Reserve ◽  
Leisure Activities ◽  
Global Measure ◽  
Interindividual Differences

Abstract Objectives Interindividual differences in cognitive aging may be explained by differences in cognitive reserve (CR) that are built up across the life span. A plausible but underresearched mechanism for these differences is that CR helps compensating cognitive decline by enhancing motivation to cope with challenging cognitive situations. Theories of motivation on cognition suggest that perceived capacity and intrinsic motivation may be key mediators in this respect. Method In 506 older adults, we assessed CR proxies (education, occupation, leisure activities), motivation (perceived capacity, intrinsic motivation), and a global measure of cognitive functioning. Results Perceived capacity, but not intrinsic motivation, significantly mediated the relation between CR and cognitive performance. Discussion Complementary with neurobiological and cognitive processes, our results suggest a more comprehensive view of the role of motivational aspects built up across the life span in determining differences in cognitive performance in old age.

scholarly journals GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms

2019 ◽  
Vol 317 (5) ◽  
pp. C953-C963 ◽  
Author(s):  
Fengling Yuan ◽  
Jiejun Zhou ◽  
Lingxiu Xu ◽  
Wenxin Jia ◽  
Lei Chun ◽  
...  
Keyword(s):  
Life Span ◽  
Gaba Receptors ◽  
Health Span ◽  
Gaba A ◽  
Inhibitory Neurotransmitter ◽  
C Elegans ◽  
Physiological Processes ◽  
Gaba Signaling ◽  
Neuronal Functions

GABA, a prominent inhibitory neurotransmitter, is best known to regulate neuronal functions in the nervous system. However, much less is known about the role of GABA signaling in other physiological processes. Interestingly, recent work showed that GABA signaling can regulate life span via a metabotropic GABAB receptor in Caenorhabditis elegans. However, the role of other types of GABA receptors in life span has not been clearly defined. It is also unclear whether GABA signaling regulates health span. Here, using C. elegans as a model, we systematically interrogated the role of various GABA receptors in both life span and health span. We find that mutations in four different GABA receptors extend health span by promoting resistance to stress and pathogen infection and that two such receptor mutants also show extended life span. Different GABA receptors engage distinct transcriptional factors to regulate life span and health span, and even the same receptor regulates life span and health span via different transcription factors. Our results uncover a novel, profound role of GABA signaling in aging in C. elegans, which is mediated by different GABA receptors coupled to distinct downstream effectors.

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