scholarly journals Prevalence of SARS-CoV-2 IgG antibodies among dental teams in Germany

2022 ◽  
Author(s):  
Maria Mksoud ◽  
Till Ittermann ◽  
Birte Holtfreter ◽  
Andreas Söhnel ◽  
Carmen Söhnel ◽  
...  
Keyword(s):  
General Population ◽  
Demographic Data ◽  
Mixed Effects ◽  
Control Measures ◽  
Mixed Effects Models ◽  
Igg Antibodies ◽  
Blood Samples ◽  
Infection Control Measures ◽  
Increased Risk ◽  
Pcr Test

Abstract Objectives During the corona pandemic, dental practices temporarily closed their doors to patients except for emergency treatments. Due to the daily occupational exposure, the risk of SARS-CoV-2 transmission among dentists and their team is presumed to be higher than that in the general population. This study examined this issue among dental teams across Germany. Materials and methods In total, 2784 participants provided usable questionnaires and dry blood samples. Dry blood samples were used to detect IgG antibodies against SARS-CoV-2. The questionnaires were analyzed to investigate demographic data and working conditions during the pandemic. Multivariable logistic mixed-effects models were applied. Results We observed 146 participants with positive SARS-CoV-2 IgG antibodies (5.2%) and 30 subjects with a borderline finding (1.1%). Seventy-four out of the 146 participants with SARS-CoV-2 IgG antibodies did not report a positive SARS-CoV-2 PCR test (50.7%), while 27 participants without SARS-CoV-2 IgG antibodies reported a positive SARS-CoV-2 PCR test (1.1%). Combining the laboratory and self-reported information, the number of participants with a SARS-CoV-2 infection was 179 (6.5%). Though after adjustment for region, mixed-effects models indicated associations of use of rubber dams (OR 1.65; 95% CI: 1.01–2.72) and the number of protective measures (OR 1.16; 95% CI: 1.01–1.34) with increased risk for positive SARS-CoV-2 status, none of those variables was significantly associated with a SARS-CoV-2 status in fully adjusted models. Conclusions The risk of SARS-CoV-2 transmission was not higher among the dental team compared to the general population. Clinical relevance. Following hygienic regulations and infection control measures ensures the safety of the dental team and their patients.

scholarly journals Healthcare Workers Infection Rate in the Era of Coronavirus Disease 2019 - in Tertiary Teaching Hospital

2021 ◽  
Vol 9 (A) ◽  
pp. 651-658
Author(s):  
Mona Mohiedden ◽  
Aml M. Said ◽  
Ahmed M. Ali ◽  
Mohammed M. Abdel Razik ◽  
Maha Ali Gad
Keyword(s):  
Healthcare Workers ◽  
Statistical Significance ◽  
Descriptive Analysis ◽  
Control Measures ◽  
University Hospitals ◽  
Cross Sectional ◽  
Infection Control Measures ◽  
Increased Risk ◽  
Tertiary Teaching ◽  
Potential Risk Factors

BACKGROUND: Healthcare workers (HCWs) are at the frontline defense against coronavirus disease 2019 (COVID-19) pandemic. AIM: The study aimed to describe the characteristics and appraise potential risk factors of COVID-19 transmission among HCWs who tested positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in one of Cairo University Hospitals. METHOD: Cross-sectional descriptive analysis of confirmed polymerase chain reaction (PCR) positive versus negative cases for COVID-19. RESULTS: Through March–June 2020, (145/846; 17%) suspected HCWs were tested for COVID-19 by PCR; out of them (70/145; 48.3%) were confirmed as positive, these positive cases represented (70/846; 8.3%) of all HCWs of the hospital. About 33% of confirmed COVID-19 positive HCWs acquired the infection from the healthcare while only (13/70; 19%) from community settings, and no clear exposure data were identified in (34/70; 48%) of cases. Most of symptomatic cases showed a positive PCR test for SARS-CoV-2 versus asymptomatic cases, p < 0.001. There was no statistical significance regarding gender, age, presence of comorbidity, workload or the type of acquisition. CONCLUSION: HCWs are at an increased risk of COVID-19 infection at the workplace. Strict implementation of infection control measures is of crucial role in preventing transmission of COVID-19 infection in health-care settings.

scholarly journals Association of anticholinergic medications and AD biomarkers with incidence of MCI among cognitively normal older adults

Neurology ◽  
2020 ◽  
Vol 95 (16) ◽  
pp. e2295-e2304 ◽  
Author(s):  
Alexandra J. Weigand ◽  
Mark W. Bondi ◽  
Kelsey R. Thomas ◽  
Noll L. Campbell ◽  
Douglas R. Galasko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Mixed Effects ◽  
Mixed Effects Models ◽  
Linear Mixed Effects Models ◽  
Cognitively Normal ◽  
Linear Mixed Effects ◽  
Anticholinergic Medications ◽  
Increased Risk ◽  
Risk Of Progression

ObjectiveTo determine the cognitive consequences of anticholinergic medications (aCH) in cognitively normal older adults as well as interactive effects of genetic and CSF Alzheimer disease (AD) risk factors.MethodsA total of 688 cognitively normal participants from the Alzheimer's Disease Neuroimaging Initiative were evaluated (mean age 73.5 years, 49.6% female). Cox regression examined risk of progression to mild cognitive impairment (MCI) over a 10-year period and linear mixed effects models examined 3-year rates of decline in memory, executive function, and language as a function of aCH. Interactions with APOE ε4 genotype and CSF biomarker evidence of AD pathology were also assessed.ResultsaCH+ participants had increased risk of progression to MCI (hazard ratio [HR] 1.47, p = 0.02), and there was a significant aCH × AD risk interaction such that aCH+/ε4+ individuals showed greater than 2-fold increased risk (HR 2.69, p < 0.001) for incident MCI relative to aCH−/ε4−), while aCH+/CSF+) individuals demonstrated greater than 4-fold (HR 4.89, p < 0.001) increased risk relative to aCH−/CSF−. Linear mixed effects models revealed that aCH predicted a steeper slope of decline in memory (t = −2.35, p = 0.02) and language (t = −2.35, p = 0.02), with effects exacerbated in individuals with AD risk factors.ConclusionsaCH increased risk of incident MCI and cognitive decline, and effects were significantly enhanced among individuals with genetic risk factors and CSF-based AD pathophysiologic markers. Findings underscore the adverse impact of aCH medications on cognition and the need for deprescribing trials, particularly among individuals with elevated risk for AD.

scholarly journals Prevalence of ADHD in Accident Victims: Results of the PRADA Study

2019 ◽  
Vol 8 (10) ◽  
pp. 1643 ◽  
Author(s):  
Kittel-Schneider ◽  
Wolff ◽  
Queiser ◽  
Wessendorf ◽  
Meier ◽  
...  
Keyword(s):  
General Population ◽  
Incidence Rate ◽  
Adult Adhd ◽  
Demographic Data ◽  
Trauma Surgery ◽  
Self Report ◽  
Stimulant Treatment ◽  
Surgery Patient ◽  
Increased Risk ◽  
History Of

Background: Recent research has shown an increased risk of accidents and injuries in ADHD patients, which could potentially be reduced by stimulant treatment. Therefore, the first aim of our study was to evaluate the prevalence of adult ADHD in a trauma surgery population. The second aim was to investigate accident mechanisms and circumstances which could be specific to ADHD patients, in comparison to the general population. Methods: We screened 905 accident victims for ADHD using the ASRS 18-item self-report questionnaire. The basic demographic data and circumstances of the accidents were also assessed. Results: Prevalence of adult ADHD was found to be 6.18% in our trauma surgery patient sample. ADHD accident victims reported significantly higher rates of distraction, stress and overconfidence in comparison to non-ADHD accident victims. Overconfidence and being in thoughts as causal mechanisms for the accidents remained significantly higher in ADHD patients after correction for multiple comparison. ADHD patients additionally reported a history of multiple accidents. Conclusion: The majority of ADHD patients in our sample had not previously been diagnosed and were therefore not receiving treatment. The results subsequently suggest that general ADHD screening in trauma surgery patients may be useful in preventing further accidents in ADHD patients. Furthermore, psychoeducation regarding specific causal accident mechanisms could be implemented in ADHD therapy to decrease accident incidence rate.

Human Immunodeficiency Virus and Treponema Pallidum Infections in Nigerian Patients with Leprosy

1994 ◽  
Vol 5 (1) ◽  
pp. 48-51
Author(s):  
C M Nwosu ◽  
S N N Nwosu ◽  
K C Okoye
Keyword(s):  
Human Immunodeficiency Virus ◽  
Sexually Transmitted Diseases ◽  
Demographic Data ◽  
Control Measures ◽  
Leprosy Patient ◽  
Control Group ◽  
Sexually Transmitted ◽  
Factors Associated ◽  
Increased Risk ◽  
Immunodeficiency Virus

Fifty-one patients were selected from 4 leprosaria in eastern Nigeria and were examined for evidence of syphilis. They were screened serologically for treponemal and human immunodeficiency virus (HIV) infections. Information about their sexual behaviour and demographic data were obtained to determine the factors associated with increased risk of contracting sexually transmitted diseases (STD). They were compared with 115 controls. The results showed that positive treponemal tests were more common in those patients living outside the leprosaria ( P<0.05). Age and sex of the patients living inside the leprosaria were not factors associated with treponemal infections. Leprosy appeared to be a factor for T. pallidum infection when compared with the control group ( P < 0.05; OR 476; CI 1.16,19.5). One leprosy patient and one control subject had positive HIV tests and there was no significant association between leprosy and HIV infection. These findings suggest the possibility of the spread of sexually transmitted diseases amongst the leprosy patient population. The importance with respect to control measures is that leprosy patients living outside leprosaria may constitute a potential reservoir for introducing sexually transmitted diseases into the leprosaria.

Eradication of Methicillin-ResistantStaphylococcus AureusFrom a Neonatal Intensive Care Unit by Active Surveillance and Aggressive Infection Control Measures

2005 ◽  
Vol 26 (7) ◽  
pp. 616-621 ◽  
Author(s):  
Jad Khoury ◽  
Marilyn Jones ◽  
Autumn Grim ◽  
Wm. Michael Dunne ◽  
Vicky Fraser
Keyword(s):  
Active Surveillance ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Multiple Gestation ◽  
Infection Control Measures ◽  
Contact Isolation ◽  
Increased Risk ◽  
Mrsa Infection ◽  
Hospital Acquired ◽  
Mrsa Colonization

AbstractObjectives:To describe an outbreak of hospital-acquired MRSA in a NICU and to identify the risk factors for, outcomes of, and interventions that eliminated it.Setting:An 18-bed, level III-IV NICU in a community hospital.Methods:Interventions to control MRSA included active surveillance, aggressive contact isolation, and cohorting and decolonization of infants and HCWs with MRSA. A case–control study was performed to compare infants with and without MRSA.Results:A cluster of 6 cases of MRSA infection between September and October 2001 represented an increased attack rate of 21.2% compared with 5.3% in the previous months. Active surveillance identified unsuspected MRSA colonization in 6 (21.4%) of 28 patients and 6 (5.5%) of 110 HCWs screened. They were all successfully decolonized. There was an increased risk of MRSA colonization and infection among infants with low birth weight or younger gestational age. Multiple gestation was associated with an increased risk of colonization (OR, 37.5; CI95, 3.9–363.1) and infection (OR, 5.36; CI95, 1.37–20.96). Gavage feeding (OR, 10.33; CI95, 1.28–83.37) and intubation (OR, 5.97; CI95, 1.22–29.31) were associated with increased risk of infection. Infants with MRSA infection had a significantly longer hospital stay than infants without MRSA (51.83 vs 21.46 days;P= .003). Rep-PCR withmectyping and PVL analysis confirmed the presence of a single common strain of hospital-acquired MRSA.Conclusion:Active surveillance, aggressive implementation of contact isolation, cohorting, and decolonization effectively eradicated MRSA from the NICU for 2½ years following the outbreak. (Infect Control Hosp Epidemiol 2005;26:616-621)

scholarly journals PREVALENCE OF LATENT TB INFECTION AMONG HEALTH CARE WORKERS, ALJAZEERA STATE TB CENTERS, SUDAN

2020 ◽  
Vol 5 (12) ◽  
pp. 465-470
Author(s):  
Juhaina Abdulraiem AL Mosharaf ◽  
Adam Abdalla Mater
Keyword(s):  
Health Care ◽  
Skin Test ◽  
Health Care Workers ◽  
Latent Tuberculosis ◽  
Health Care Facilities ◽  
Control Measures ◽  
Treatment Center ◽  
Infection Control Measures ◽  
Care Workers ◽  
Increased Risk

Health care workers (HCW) are at increased risk of latent tuberculosis infection (LTBI) from occupational exposure to Mycobacterium tuberculosis. The objective was to determine the prevalence and risk factors for LTBI among primary HCW in Aljazeera state Sudan. We conducted an analytical study, among HCW in TB treatment center using a structured questionnaire and an evaluated for LTBI using the tuberculin skin test among 367 HCW, the LTBI prevalence was 35.7%. (64.5%), We found that the following factors associated with LTBI in HCW were in age group 30-40 years was 63% ,75.2% of the participants didn't do the skin test for TB, and the high risk among the  lab technician represented 41.2%. Our study recommended implementation of sound TB infection control measures in all health care facilities with patients suspected of having infectious.

scholarly journals Knowledge, Perceptions, and Attitudes Regarding COVID-19 and Infection Control Measures Against it among Dental Students in Saudi Arabia

2021 ◽  
Vol 15 (1) ◽  
pp. 479-486
Author(s):  
Tahani M. Alharbi ◽  
Afrah M. Alharbi ◽  
Rafal K. Khayyat ◽  
Jawaher B. Aldaadi ◽  
Ibtesam K. Afifi
Keyword(s):  
Saudi Arabia ◽  
Risk Perception ◽  
Infection Control ◽  
Dental Students ◽  
Control Measures ◽  
Dental Practice ◽  
Cross Sectional ◽  
Infection Control Measures ◽  
Perceptions And Attitudes ◽  
Increased Risk

Background Coronavirus disease (COVID-19) is a highly infectious disease caused by an RNA virus named SARS CoV2. The increased risk of infection by this virus among dental students necessitates updated knowledge and highlights their important role in preventing and controlling its transmission. Objective: This study aims to assess knowledge, perceptions, and attitudes regarding COVID-19 and infection control measures among dental students in Saudi Arabia. Methods: A cross-sectional study was conducted among dental students in different Saudi universities using an online self-administered questionnaire. It gathered data on students’ demographic information, knowledge of COVID-19 and infection control measures, risk perception and attitudes toward the disease, and their preparedness for treating infected patients. Results: A total of 327 dental students responded to the questionnaire. Of these students, 92.4% had received training in infection control in dental practice, but only 24.2% had attended training regarding COVID-19. The majority of students had adequate knowledge regarding the modes of transmission and the common symptoms of COVID-19, with statistically significant total mean knowledge scores among students in different academic years (p<0.05). A large percentage of the students (92.7%) agreed that the use of rubber dams or high-volume saliva ejectors could reduce the possibility of transmitting infection. However, 58.4% of the students disagreed that intraoral dental radiographs should be avoided to reduce the possibility of transmitting infection. Conclusion: Although knowledge of and risk perception concerning COVID-19 among students is good, additional training sessions integrating recent international guidelines for infection control are required to update their knowledge and achieve safe dental practice.

scholarly journals Anaesthesia and infection control in cesarean section of pregnant women with coronavirus disease 2019 (COVID-19)

2020 ◽  
Author(s):  
LinLi Yue ◽  
Lefei Han ◽  
Qiannan Li ◽  
Min Zhong ◽  
Jun Wang ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Infection Control ◽  
Pregnant Women ◽  
Postoperative Analgesia ◽  
Demographic Data ◽  
Perinatal Care ◽  
Care Quality ◽  
Control Measures ◽  
Obstetrical Anaesthesia ◽  
Infection Control Measures

AbstractBackgroundThe coronavirus disease 2019 (COVID-19) first emerged in Wuhan, China, and soon caused an ongoing pandemic globally. In this study we conducted a retrospective study to evaluate the safety and efficacy of combined spinal-epidural anaesthesia (CSEA) and infection control measures on perinatal care quality of 30 pregnant women with confirmed and suspected COVID-19.MethodsIndividual demographic data, clinical outcomes, laboratory investigations of pregnant women and their newborns were collected from electronic medical records of the Maternal and Children Health Hospital of Hubei Province, during January 24 to February 29, 2020. Anaesthesia and surgery results were compared between pregnant women with confirmed and suspected COVID-19 infection.ResultsUsing CSEA in cesarean section was effective and safe for pregnant women with confirmed and suspected COVID-19 infection. Administration of dezocine and morphine was effective as postoperative analgesia, and well tolerated in COVID-19 patients. The assessment of surgery outcomes also showed similar results in both confirmed and suspected cases. No respiratory failure nor distress were found in the mothers with confirmed COVID-19 infection and their neonates. None of these patients experienced severe obstetric complications related to anaesthesia and surgeries. No COVID-19 infection was reported in the neonates born to the mothers with confirmed COVID-19 infection and healthcare workers in these operations.ConclusionsIn cesarean section for pregnant women with COVID-19 infection, CSEA was safe and efficient in achieving satisfactory obstetrical anaesthesia and postoperative analgesia. No cross-infection occurred in the HCWs working in these operations.

scholarly journals Knowledge, Attitude, Behavior, and Stress Related to COVID-19 among Undergraduate Health Care Students in Jordan

2020 ◽  
Vol 14 (S 01) ◽  
pp. S50-S55
Author(s):  
Ruba M. Mustafa ◽  
Nasr N. Alrabadi ◽  
Ruwaida Z. Alshali ◽  
Yousef S. Khader ◽  
Dana M. Ahmad
Keyword(s):  
Health Care ◽  
Social Behavior ◽  
Infection Control ◽  
Stress Level ◽  
Demographic Data ◽  
Dental Students ◽  
Health Science ◽  
Control Measures ◽  
Health Care Students ◽  
Infection Control Measures

Abstract Objectives This study aimed to assess knowledge, attitude, and infection control measures related to the coronavirus disease 2019 (COVID-19) pandemic outbreak among Jordanian health care students. Besides, their social behavior and stress level regarding COVID-19 infection were assessed. Materials and Methods An online questionnaire was distributed to medical, dental, pharmacy, nursing, and applied health science students in Jordan during the COVID-19 outbreak quarantine in March 2020. The questionnaire comprised 38 questions assessing demographic data, knowledge, attitude, risk perception, and stress level toward COVID-19. Questions regarding infection control measures and social behavior after the quarantine were also included. Statistical Analysis Independent samples t-test, one-way analysis of variance (ANOVA), and chi-square at a significance level of 5% were used for data analysis. Results A total number of 935 responses were collected. The knowledge score of 55.72% of participants was satisfactory and it was higher for the clinical years’ students compared with the basic years’ students (p = 0.000) (descending order: sixth year > fifth year > fourth year > third year > first year > second year). Also, knowledge scores were significantly higher for medical and dental students than other disciplines (descending order: medicine, dentistry, pharmacy, nursing/applied) (p = 0.000). The social media (89.1%) and TV or radio (69.5%) were mainly routes through which participants heard about COVID-19. Moderate and justifiable feelings about COVID-19 were found in the majority of the participants. Conclusion Although the majority of students showed good knowledge scores, few of them appeared to have a serious lack of knowledge. Therefore, proper education and mentoring are necessary for students before reopening the university campuses.

scholarly journals Latent tuberculosis infection in healthcare workers in low- and middle-income countries: an updated systematic review

2019 ◽  
Vol 53 (4) ◽  
pp. 1801789 ◽  
Author(s):  
Lika Apriani ◽  
Susan McAllister ◽  
Katrina Sharples ◽  
Bachti Alisjahbana ◽  
Rovina Ruslami ◽  
...  
Keyword(s):  
Systematic Review ◽  
Infection Control ◽  
Healthcare Workers ◽  
Latent Tuberculosis ◽  
Annual Incidence ◽  
Control Measures ◽  
Middle Income ◽  
Middle Income Countries ◽  
Infection Control Measures ◽  
Increased Risk

Healthcare workers (HCWs) are at increased risk of latent tuberculosis (TB) infection (LTBI) and TB disease.We conducted an updated systematic review of the prevalence and incidence of LTBI in HCWs in low- and middle-income countries (LMICs), associated factors, and infection control practices. We searched MEDLINE, Embase and Web of Science (January 1, 2005–June 20, 2017) for studies published in any language. We obtained pooled estimates using random effects methods and investigated heterogeneity using meta-regression.85 studies (32 630 subjects) were included from 26 LMICs. Prevalence of a positive tuberculin skin test (TST) was 14–98% (mean 49%); prevalence of a positive interferon-γ release assay (IGRA) was 9–86% (mean 39%). Countries with TB incidence ≥300 per 100 000 had the highest prevalence (TST: pooled estimate 55%, 95% CI 41–69%; IGRA: pooled estimate 56%, 95% CI 39–73%). Annual incidence estimated from the TST was 1–38% (mean 17%); annual incidence estimated from the IGRA was 10–30% (mean 18%). The prevalence and incidence of a positive test was associated with years of work, work location, TB contact and job category. Only 15 studies reported on infection control measures in healthcare facilities, with limited implementation.HCWs in LMICs in high TB incidence settings remain at increased risk of acquiring LTBI. There is an urgent need for robust implementation of infection control measures.

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