scholarly journals Measurement Science in the Circulatory System

2013 ◽  
Vol 7 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Casey M. Jones ◽  
Sandra M. Baker-Groberg ◽  
Flor A. Cianchetti ◽  
Jeremy J. Glynn ◽  
Laura D. Healy ◽  
...  
Keyword(s):  
Circulatory System ◽  
Measurement Science

Features of mortality of the male population of the monotown, which is the industrial center of non-ferrous metallurgy

2020 ◽  
pp. 772-772
Author(s):  
G. I. Tikhonova ◽  
M. S. Bryleva ◽  
T. Yu. Gorchakova
Keyword(s):  
Ferrous Metallurgy ◽  
Digestive System ◽  
Circulatory System ◽  
Mortality Rates ◽  
Malignant Neoplasms ◽  
Male Population ◽  
Murmansk Region ◽  
Metallurgical Company ◽  
Industrial Center

Standardized mortality rates of the male population aged 15-59 in Monchegorsk, where the Kola mining and metallurgical company is located, were higher relative to the Murmansk region and Russia: from diseases of the circulatory system by 34.8% and 52.1%, respectively, from malignant neoplasms by 26.3% and 19.4%, from diseases of the digestive system by 59.0% and 36.3%.

Working conditions and the formation of health risks among workers of the petrochemical industry engaged in the production of methanol and its derivatives

2019 ◽  
pp. 266-271
Author(s):  
Nina M. Meshchakova ◽  
Marina P. Dyakovich ◽  
Salim F. Shayakhmetov
Keyword(s):  
Working Conditions ◽  
Health Risks ◽  
Quantitative Assessment ◽  
Circulatory System ◽  
Medical Examination ◽  
Physical Factors ◽  
Labor Intensity ◽  
Industrial Noise ◽  
Harmful Substances ◽  
The Impact

Introduction.Methanol and its derivatives occupy one of the leading places among the main organic synthesis intermediates in terms of their importance and scale of production. According to experts, by 2027 the global demand for methanol can reach 135 million tons, the annual growth will be about 5.5%. However, there is little information regarding the assessment of working conditions and occupational risks for workers in modern methanol production and its derivatives.The aim of the studyis hygienic assessment of working conditions and the formation of health risks in workers of modern production of methanol and methylamines.Materials and methods.The assessment of the main adverse factors of production is given. When studying the state of health, objective indicators (the results of an in-depth medical examination) and subjective (the results of a quantitative assessment of the risks of the main pathological syndromes associated with health) are considered.Results.According to long-term observations, the concentration of harmful substances in the air of the working area, indicators of labor severity, parameters of physical factors met hygienic requirements, with the exception of industrial noise exceeding the maximum permissible level, as well as labor intensity of 1 degree. The General assessment of working conditions corresponds to the category of harmful 2 degrees (3.2). According to the results of the medical examination and quantitative assessment of the risks of health disorders in workers, the most significant were functional disorders and diseases of the circulatory system. The levels of somatic pathology on the part of the main body systems were significantly higher in apparatchiks compared to the engineering and technical personnel (ETP).Conclusions:In the production of methyl alcohol and methylamines, the main hygienic importance is the impact on workers of the complex of harmful substances of 1-IV hazard classes in low concentrations, increased levels of industrial noise, labor intensity of 1 degree. According to the subjective assessment of health and medical examination, the greatest prevalence of health risks in workers was observed from the circulatory system, and the levels of the revealed somatic pathology were statistically significantly higher in apparatchiks compared with the ETP.

Study of functional state of microcirculatory channel system in periodontal tissues in persons of different age groups

2020 ◽  
Vol 20 (2) ◽  
pp. 88-94
Author(s):  
L. Yu. Orekhova ◽  
A. A. Petrov ◽  
E. S. Loboda ◽  
I. V. Berezkina ◽  
K. V. Shadrina
Keyword(s):  
Functional State ◽  
Age Groups ◽  
Peripheral Resistance ◽  
Circulatory System ◽  
Structural Features ◽  
Periodontal Tissues ◽  
Non Invasive ◽  
Age Related ◽  
Group 12 ◽  
Therapeutic Measures

Relevance. The study of age-related features of microcirculation in periodontal tissues, using non-invasive functional research methods, allows us to develop the optimal range of therapeutic measures, as well as form a “personalized therapeutic case”.Purpose. Study of the functional state of the microvasculature in the tissues of the parodont in individuals of various age groups.Materials and methods. A standard dental examination of 80 patients was carried out, the sample of participants was ranked in 4 groups by age: 1 group – 12 years old, 2 group – 15 years old, 3 group – from 16 to 18 years old, 4 group – from 22 to 24 years old. Hygiene and periodontal indices were determined for all patients, such as papillarymarginal-alveolar (PMA) in the Parma modification, the Mulleman bleeding index in the Cowell modification (SBI), and the simplified Green Vermillion index of oral hygiene (OHI–s), caries intensity indicators for a permanent bite (CPI), as well as ultrasound dopplerography of periodontal tissues using the apparatus "Minimax-Doppler-K".Results. When studying microcirculation in periodontal tissues, distinctive characteristics of linear (Vas) and volumetric (Qas) blood flow rates, as well as indicators of pulsation indices (PI) and peripheral resistance (RI) in people of different age groups were recorded.Conclusions. This study confirms the presence of various hemodynamic indicators of periodontal tissues in the studied groups, which is due to structural features of the circulatory system in age periods.

Towards a Fast Dynamic Model of the Human Circulatory System

2011 ◽  
Author(s):  
M. A. Green ◽  
C. R. Kaplan ◽  
J. P. Boris ◽  
E. S. Oran
Keyword(s):  
Dynamic Model ◽  
Circulatory System ◽  
Fast Dynamic ◽  
Human Circulatory System

Hyperuricemia and Cardiovascular Disease

2019 ◽  
Vol 25 (6) ◽  
pp. 700-709 ◽  
Author(s):  
Shuangshuang Zhang ◽  
Yong Wang ◽  
Jinsong Cheng ◽  
Ning Huangfu ◽  
Ruochi Zhao ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Chronic Kidney Disease ◽  
Uric Acid ◽  
Kidney Disease ◽  
Kidney Stones ◽  
Treatment Plan ◽  
Circulatory System ◽  
Special Focus ◽  
Positive Effects

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.

Physiology of Larval Feeding

2018 ◽  
Keyword(s):  
Growth And Development ◽  
Marine Invertebrate ◽  
Larval Growth ◽  
Circulatory System ◽  
Future Research ◽  
Larval Feeding ◽  
Digestive Physiology ◽  
Larval Body ◽  
The Individual ◽  
Invertebrate Larvae

The functional properties of marine invertebrate larvae represent the sum of the physiological activities of the individual, the interdependence among cells making up the whole, and the correct positioning of cells within the larval body. This chapter examines physiological aspects of nutrient acquisition, digestion, assimilation, and distribution within invertebrate larvae from an organismic and comparative perspective. Growth and development of larvae obviously require the acquisition of “food.” Yet the mechanisms where particulate or dissolved organic materials are converted into biomass and promote development of larvae differ and are variably known among groups. Differences in the physiology of the digestive system (secreted enzymes, gut transit time, and assimilation) within and among feeding larvae suggest the possibility of an underappreciated plasticity of digestive physiology. How the ingestion of seawater by and the existence of a circulatory system within larvae contribute to larval growth and development represent important topics for future research.

scholarly journals The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine

2021 ◽  
Vol 22 (15) ◽  
pp. 7931
Author(s):  
Ning Liu ◽  
Shiqiang Sun ◽  
Pengjie Wang ◽  
Yanan Sun ◽  
Qingjuan Hu ◽  
...  
Keyword(s):  
Cell Metabolism ◽  
Circulatory System ◽  
Vital Role ◽  
The Body ◽  
Neuroendocrine Cells ◽  
Intestinal Lumen ◽  
Paracrine Signaling ◽  
Inflammatory Conditions ◽  
Epithelial Development ◽  
Ec Cells

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is reported to modulate the development and neurogenesis of the enteric nervous system, gut motility, secretion, inflammation, sensation, and epithelial development. Approximately 95% of 5-HT in the body is synthesized and secreted by enterochromaffin (EC) cells, the most common type of neuroendocrine cells in the gastrointestinal (GI) tract, through sensing signals from the intestinal lumen and the circulatory system. Gut microbiota, nutrients, and hormones are the main factors that play a vital role in regulating 5-HT secretion by EC cells. Apart from being an important neurotransmitter and a paracrine signaling molecule in the gut, gut-derived 5-HT was also shown to exert other biological functions (in autism and depression) far beyond the gut. Moreover, studies conducted on the regulation of 5-HT in the immune system demonstrated that 5-HT exerts anti-inflammatory and proinflammatory effects on the gut by binding to different receptors under intestinal inflammatory conditions. Understanding the regulatory mechanisms through which 5-HT participates in cell metabolism and physiology can provide potential therapeutic strategies for treating intestinal diseases. Herein, we review recent evidence to recapitulate the mechanisms of synthesis, secretion, regulation, and biofunction of 5-HT to improve the nutrition and health of humans.

scholarly journals Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Vengala Rao Yenuganti ◽  
Dirk Koczan ◽  
Jens Vanselow
Keyword(s):  
Oleic Acid ◽  
Granulosa Cells ◽  
System Development ◽  
Circulatory System ◽  
Bioinformatic Analysis ◽  
Negative Energy ◽  
Tissue Remodelling ◽  
Gonadotropin Secretion ◽  
Genome Wide

Abstract Background Metabolic stress, as negative energy balance on one hand or obesity on the other hand can lead to increased levels of free fatty acids in the plasma and follicular fluid of animals and humans. In an earlier study, we showed that increased oleic acid (OA) concentrations affected the function of cultured bovine granulosa cells (GCs). Here, we focus on genome wide effects of increased OA concentrations. Results Our data showed that 413 genes were affected, of which 197 were down- and 216 up-regulated. Specifically, the expression of FSH-regulated functional key genes, CCND2, LHCGR, INHA and CYP19A1 and 17-β-estradiol (E2) production were reduced by OA treatment, whereas the expression of the fatty acid transporter CD36 was increased and the morphology of the cells was changed due to lipid droplet accumulation. Bioinformatic analysis revealed that associated pathways of the putative upstream regulators “FSH” and “Cg (choriogonadotropin)” were inhibited and activated, respectively. Down-regulated genes are over-represented in GO terms “reproductive structure/system development”, “ovulation cycle process”, and “(positive) regulation of gonadotropin secretion”, whereas up-regulated genes are involved in “circulatory system development”, “vasculature development”, “angiogenesis” or “extracellular matrix/structure organization”. Conclusions From these data we conclude that besides inhibiting GC functionality, increased OA levels seemingly promote angiogenesis and tissue remodelling, thus suggestively initiating a premature fulliculo-luteal transition. In vivo this may lead to impeded folliculogenesis and ovulation, and cause sub-fertility.

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