A review of machines and devices to potentize homeopathic medicines

Homeopathy ◽  
2017 ◽  
Vol 106 (04) ◽  
pp. 240-249 ◽  
Author(s):  
Abhirup Basu ◽  
Akkihebbal Krishnamurthy Suresh ◽  
Shantaram Govind Kane ◽  
Jayesh Ramesh Bellare
Keyword(s):  
Energy Dissipation ◽  
Review Paper ◽  
Mechanical Efficiency ◽  
Human Element ◽  
The Past ◽  
Physico Chemical ◽  
Chemical Efficiency ◽  
Mode Of Operation ◽  
Manual Labour ◽  
Turbulence Generation

Background: Potentization, consisting of serial dilution and succussion, is a key step in the manufacture of homeopathic medicines. Originally prescribed as a manual process, several attempts at mechanization have been published, patented and even commercialised in order to remove the human element and introduce reproducibility without drudgery. Various machines have been used over the years to prepare homeopathic medicines. Although these machines follow the same principles, i.e. energetically mixing the medicines and diluting them significantly, their mode of operation is different from each other. Methods: This review paper surveys the main methods of preparation of homeopathic medicines. The main machines discussed are: Boericke's potentizer, Tyler Kent's instrument, John Alphonse's machine and the fluxion potentizer, which were used in the past, as well as more recent potentizers like arm-and-weight instruments, the K-Tronic potentizer and Quinn's machine. We review the construction and operating principle of each of these machines, along with their advantages and limitations. A scheme for relative performance assessment of these machines is proposed based on the parameters mechanical efficiency, physico-chemical efficiency, turbulence generation, energy dissipation, and accuracy of dilution. Results: Quinn's machine and the arm-and-weight potentizer perform well for generating turbulence due to high impaction forces, while John Alphonse's machine is much more accurate in diluting the homeopathic medicines at every step. Conclusions: Both the commercial potentizers, Quinn's machine and the K-Tronic potentizer, are completely automated and therefore reduce the manual labour and variation in succussive forces during each step, which may produce uniformity in physico-chemical changes within the resulting homeopathic medicines.

Progress and Prospects in Translating Nanobiotechnology in Medical Theranostics

2020 ◽  
Vol 16 (5) ◽  
pp. 685-707 ◽  
Author(s):  
Amna Batool ◽  
Farid Menaa ◽  
Bushra Uzair ◽  
Barkat Ali Khan ◽  
Bouzid Menaa
Keyword(s):  
Biological Properties ◽  
Chemical Characteristics ◽  
Intrinsic Properties ◽  
The Past ◽  
Profound Influence ◽  
Functionalized Nanomaterials ◽  
Physico Chemical ◽  
Properties Of Materials ◽  
Targeted Drug ◽  
And Performance

: The pace at which nanotheranostic technology for human disease is evolving has accelerated exponentially over the past five years. Nanotechnology is committed to utilizing the intrinsic properties of materials and structures at submicroscopic-scale measures. Indeed, there is generally a profound influence of reducing physical dimensions of particulates and devices on their physico-chemical characteristics, biological properties, and performance. The exploration of nature’s components to work effectively as nanoscaffolds or nanodevices represents a tremendous and growing interest in medicine for various applications (e.g., biosensing, tunable control and targeted drug release, tissue engineering). Several nanotheranostic approaches (i.e., diagnostic plus therapeutic using nanoscale) conferring unique features are constantly progressing and overcoming all the limitations of conventional medicines including specificity, efficacy, solubility, sensitivity, biodegradability, biocompatibility, stability, interactions at subcellular levels. : This review introduces two major aspects of nanotechnology as an innovative and challenging theranostic strategy or solution: (i) the most intriguing (bare and functionalized) nanomaterials with their respective advantages and drawbacks; (ii) the current and promising multifunctional “smart” nanodevices.

Individual effectiveness in outsourcing

2006 ◽  
Vol 25 (2) ◽  
pp. 127-133
Author(s):  
Sumita Raghuram
Keyword(s):  
Customer Satisfaction ◽  
Cultural Differences ◽  
Employee Selection ◽  
Poor Performance ◽  
Communication Media ◽  
Intensive Training ◽  
Human Element ◽  
The Past ◽  
Geographical Distances

Outsourcing has grown enormously over the past few years, however, most of the attention so far has focused on the economics of the transaction, and much less on the human element involved in the transaction. In this paper I focus on call agents and my observations are based upon existing literature and my personal interviews. I suggest that it is challenging for them to identify with client organizations because of cultural differences, tacit contexts and lean communication media used to connect across vast geographical distances. The weak client identification may result in poor performance, inability to build trust with customers and long-term customer satisfaction. However, there are differences across individuals in their ability to deal with these challenges. Those who have a higher self-efficacy, higher pro-activeness and higher cultural intelligence may be more capable than others in their effectiveness. Likewise, organization initiated practices such as careful employee selection, intensive training and use of visible markers of identity may heighten client identification.

scholarly journals Healthcare Applications of Artificial Intelligence and Analytics: A Review and Proposed Framework

2020 ◽  
Vol 10 (18) ◽  
pp. 6553
Author(s):  
Sabrina Azzi ◽  
Stéphane Gagnon ◽  
Alex Ramirez ◽  
Gregory Richards
Keyword(s):  
Artificial Intelligence ◽  
Chronic Care ◽  
Review Paper ◽  
Research Community ◽  
Patient Needs ◽  
Care Needs ◽  
Healthcare Applications ◽  
Medical Specialties ◽  
The Past ◽  
Promising Application

Healthcare is considered as one of the most promising application areas for artificial intelligence and analytics (AIA) just after the emergence of the latter. AI combined to analytics technologies is increasingly changing medical practice and healthcare in an impressive way using efficient algorithms from various branches of information technology (IT). Indeed, numerous works are published every year in several universities and innovation centers worldwide, but there are concerns about progress in their effective success. There are growing examples of AIA being implemented in healthcare with promising results. This review paper summarizes the past 5 years of healthcare applications of AIA, across different techniques and medical specialties, and discusses the current issues and challenges, related to this revolutionary technology. A total of 24,782 articles were identified. The aim of this paper is to provide the research community with the necessary background to push this field even further and propose a framework that will help integrate diverse AIA technologies around patient needs in various healthcare contexts, especially for chronic care patients, who present the most complex comorbidities and care needs.

Human Factors in Classification and Certification

2005 ◽  
Author(s):  
James C. Card ◽  
Clifford C. Baker ◽  
Kevin P. McSweeney ◽  
Denise B. McCafferty
Keyword(s):  
Human Factors ◽  
Public Interest ◽  
Natural Environment ◽  
18Th Century ◽  
Maritime Safety ◽  
The Public ◽  
Human Element ◽  
The Past ◽  
Design Construction

Since the 18th century, Classification Societies have served the public interest by promoting the security of life, property, and the natural environment. This has been accomplished primarily through the development and verification of standards for the design, construction, and maintenance of marine facilities, however, new insights gained over the past decade have motivated maritime safety organizations to better address the contribution of the human element to maritime casualties and accidents.

scholarly journals 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6755
Author(s):  
Maria J. Matos ◽  
Eugenio Uriarte ◽  
Lourdes Santana
Keyword(s):  
Medicinal Chemistry ◽  
Review Paper ◽  
Relevant Literature ◽  
Natural Origin ◽  
Drug Candidates ◽  
Heterocyclic Molecules ◽  
The Past ◽  
New Drug ◽  
Privileged Scaffold

3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley.

scholarly journals Monitoring and risk assessment for groundwater sources in rural communities of Romania (GROUNDWATERISK)

2019 ◽  
Vol 5 ◽  
Author(s):  
Oana Teodora Moldovan ◽  
Rannveig Øvrevik Skoglund ◽  
Horia Leonard Banciu ◽  
Alexandra Dinu Cucoș ◽  
Erika Andrea Levei ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Drinking Water ◽  
Rural Communities ◽  
Groundwater Resources ◽  
Molecular Techniques ◽  
The Past ◽  
Physico Chemical ◽  
Groundwater Ecosystems ◽  
Alternative Sources ◽  
Agricultural Areas

In the past 100 years, a decreasing rainfall trend has been recorded on Romanian territory, a trend that continues today. Therefore, realistic estimation of the groundwater resources is crucial, especially for the rural communities lacking the economic power to use alternative sources of drinking water. The groundwater sources used by rural communities in Romania generally originate directly from caves, wells or springs with no proper evaluation of the water quality. Groundwater is exposed to different pollutants, as bats' guano in caves, fertilizers in agricultural areas or livestock (cattle, sheep, goats, etc.) farms on the surface. On the other hand, the water extracted directly from inside the caves is affecting groundwater ecosystems, highly vulnerable to any human impact and neglected by European legislation so far. The project aims to monitor, during two consecutive years, groundwater sources with different degrees of above- and underground pollution, from different regions of Romania. To achieve the goals of the project, a multidisciplinary monitoring strategy that will include measurements of hydrological, physico-chemical and biological (microbiology and aquatic invertebrates’ assessment) parameters alongside the quantification of radon and stable isotopes, rainfall or possible inflows of water. The specific outcomes of this project are: i) to test, develop and validate a new, more rapid and efficient method for monitoring and risk assessment of groundwater sources – and not only – by using molecular techniques, and propose this method to the water agencies in Romania; ii) to propose for Romanian authorities to implement a harmonized coherent methodology to measure radon concentration in water, as a consequence of EURATOM Directive; and iii) to educate local communities that are using groundwater as source for drinking water and raise young people’s awareness on the benefits of ecosystem services provided by the groundwater.

Citrus bergamia, Risso: the peel, the juice and the seed oil of the bergamot fruit of Reggio Calabria (South Italy).

2020 ◽  
pp. 522
Author(s):  
Giuffrè Angelo Maria ◽  
Nobile Riccardo
Keyword(s):  
Seed Oil ◽  
Citrus Fruit ◽  
Total Flavonoids ◽  
Citrus Fruits ◽  
South Italy ◽  
The Past ◽  
Functional Aspects ◽  
Physico Chemical ◽  
Similar Quantity ◽  
Citrus Bergamia

Bergamot is a characteristic citrus fruit of the province of Reggio Calabria (South Italy) and until today it was mainly known for the production of its peel essential oil. Since some year, due to the positive feedback from consumers, there has been a growing interest in the bergamot juice which in the past was not used as a beverage because it was considered very sour. The recent studies on the functional aspects of citrus fruits and therefore also on bergamot have made this fruit known to a new youth. They exist three cultivars: Castagnaro, Fantastico and Femminello. In this study the biometrics of the fruits and the physico-chemical characteristics of the juice have been taken into consideration, such as: Brix degrees, pH, pulp content in the squeezed juice, turbidity, acidity, vitamin C, Formol number, single and total flavonoids. Total flavonoids in the bergamot juice ranged between 362 and 520 mg/L whereas in the Cloudy juice they ranged between 4660 and 8468 mg/L. The composition in fatty acids and in sterols of the seed oil of this fruit was also analysed to evaluate its potential. Oleic acid (30.15-34.36%) and linoleic acid (27.01-29.84%) were found in similar quantity, while the most present sterol was β-sitosterol (76.9-79.2%).

University Startup Accelerators: Startup Launchpads or Vehicles for Entrepreneurial Learning?

2020 ◽  
pp. 251512742093175
Author(s):  
Lynn E. Metcalf ◽  
Thomas M. Katona ◽  
Jonathan L. York
Keyword(s):  
Return On Investment ◽  
Future Research ◽  
Uniform Structure ◽  
Primary Role ◽  
Entrepreneurial Ecosystem ◽  
The Past ◽  
Mode Of Operation ◽  
The University ◽  
Insight Into

Over the past decade, universities have invested heavily in startup accelerator programs; however, their role in the university entrepreneurial ecosystem is ambiguous. Are university startup accelerators intended to educate or are they created to facilitate business starts and to contribute to regional economic development? In contrast, most private-sector startup accelerators serve a consistent and differentiated role in the entrepreneurial ecosystem—they provide programming and resources to startups to increase the probability of a return on investment. Understanding the role of university startup accelerators is an important precursor to evaluating their impact and whether or not the return is worth the considerable investment. In this study, we poll university accelerator directors to gain their perspective on the role(s) that university startup accelerators play and to identify how they are structured and operated. Our research reveals a fairly uniform structure and mode of operation. While facilitating business starts is a key role for some, it confirms education as the primary role for university startup accelerators. We outline appropriate means of assessing the learning that takes place in accelerator programs, offer insight into how these findings can help accelerator directors deliver on outcomes and demonstrate impact, and propose avenues for future research.

scholarly journals Religion, Human Rights, and Forensic Activism: The Search for the Disappeared in Latin America

Religions ◽  
2020 ◽  
Vol 11 (11) ◽  
pp. 601
Author(s):  
María Soledad Catoggio
Keyword(s):  
Human Rights ◽  
The Public ◽  
The Past ◽  
Making Sense ◽  
Qualitative Research Design ◽  
Human Rights Movement ◽  
Mode Of Operation ◽  
Scientific Expertise ◽  
Scientific System ◽  
Depth Interviews

This paper systematizes and analyzes the links and exchanges between the Argentine Forensic Anthropology Team (Equipo Argentino de Antropología Forense (EAAF)) and the world of religion. My hypothesis is that these links are inextricable from the mode of operation that defined the EAAF, which can be called “forensic activism”. This kind of activism, outside the State, combined scientific expertise with humanitarian sensitivity, defined by its autonomy from the human rights movement and the national scientific system (both academic and university). Moreover, religion emerged constantly from the type of work undertaken, between the living and the dead. Thus, beliefs, with their prohibitions, rituals, and ways of making sense of suffering and their tools for coming to terms with grief, coexisted with the EAAF’s development. These findings emerge from a qualitative research design combining document analysis, in-depth interviews, and participative observation of scientific disclosure open to the public provided by the EAAF over the past three years.

scholarly journals On the cataphoresis of gliadin Part—The adsorption of gliadin on quartz

1934 ◽  
Vol 147 (860) ◽  
pp. 1-10 ◽  
Keyword(s):  
Electric Field ◽  
Chemical Properties ◽  
Plant Proteins ◽  
The Past ◽  
Physico Chemical ◽  
Inert Particles

There have been few systematic investigations of the physico-chemical properties of the more important plant proteins; such investigations as have been carried out in the past have concerned themselves almost entirely with the better known animal proteins. It was, therefore, thought desirable to make a study of the physico-chemical properties of the protein gliadin, which, together with glutenin, forms the chief constituent of the gluten of flour. Of all the methods employed for determining the mobility of colloid ions in an electric field, the micro-cataphoretic method is the most exact. In studying the micro-cataphoresis of protein sols in which the particles are not visible in the ultramicroscope, it has been usual to make measurements using inert particles coated with protein. Although it was found possible to obtain gliadin sols containing visible submicrons, it was decided to make observations also on quartz particles covered with gliadin.

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