scholarly journals Estimating the potential impact fraction of hypertension as the main risk factor of stroke: Application of the distribution shift method

2015 ◽  
Vol 5 (3) ◽  
pp. 231 ◽  
Author(s):  
Azam Biderafsh ◽  
Manoochehr Karami ◽  
Javad Faradmal ◽  
Jalal Poorolajal
Keyword(s):  
Risk Factor ◽  
Main Risk Factor ◽  
Shift Method ◽  
Potential Impact ◽  
Potential Impact Fraction

Eyelid Dermatitis and Contact Sensitization to Nickel: Results from an Italian Multi-Centric Observational Study

2019 ◽  
Vol 19 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Alessandro Borghi ◽  
Monica Corazza ◽  
Elisa Maietti ◽  
Cataldo Patruno ◽  
Maddalena Napolitano ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Contact Sensitization ◽  
Main Risk Factor ◽  
Nickel Allergy ◽  
Cross Sectional ◽  
Triggering Factor ◽  
Irritant Action ◽  
Allergic Contact

Background: Due to the sensitizing constituents of eye cosmetics, allergic contact dermatitis is considered a frequent cause of eyelid dermatitis. An association between eyelid dermatitis and nickel contained in make-ups remains controversial. Objective: The study aimed to assess the association between nickel allergy, the use of pigmented makeup products and self-reported eyelid dermatitis. Method: This multi-centric, cross-sectional study enrolled 165 women sensitized to nickel (patients) and 103 women without intolerance to metals (controls). We recorded: demographics, atopy, use of pigmented eye cosmetics (mascara, eyeshadow, eyeliner, eyebrow pencil), and previous eyelid dermatitis. Among the patients, any co-sensitization to cosmetics or metals was recorded. Results: 87.3% of the patients and 91.3% of the controls reported their use of eye make-up; 44.9% and 52.4%, respectively, reported previous episodes of eyelid dermatitis, without significant differences. The occurrence of eyelid dermatitis was significantly associated with the use of eye make-up products, both in general and considering each product separately. Age, atopy, or co-sensitization to other metals or cosmetics did not affect the occurrence of eyelid dermatitis. Conclusion: Nickel allergy should not be considered the main risk factor for eyelid dermatitis. The use of pigmented eye make-up may be a triggering factor for eyelid dermatitis, probably due to an irritant action.

Parenteral nutrition related cholestasis: infection as the main risk factor

1995 ◽  
Vol 71 (5) ◽  
pp. 255-260
Author(s):  
Paulo R. Antonacci Carvalho ◽  
Themis Reverbel da Silveira
Keyword(s):  
Risk Factor ◽  
Parenteral Nutrition ◽  
Main Risk Factor

Regulatory effect of volatile compounds in fermented alcoholic beverages on gut microbiota and serum metabolism in mouse model

2021 ◽  
Author(s):  
Mei Ji ◽  
Cheng Fang ◽  
Wei Jia ◽  
Hai Du ◽  
Yan Xu
Keyword(s):  
Risk Factor ◽  
Liver Disease ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Volatile Compounds ◽  
Alcoholic Liver Disease ◽  
Alcoholic Beverages ◽  
Regulatory Effect ◽  
Main Risk Factor

Ethanol (EtOH) is the main risk factor for alcoholic liver disease. However, fermented alcoholic beverages contain not only ethanol but also various volatile compounds. Currently, effects of volatile compounds in...

Social and individual factors associated with condom use among single youths: an analysis of the 2018 Cameroon Demographic and Health Survey

2021 ◽  
pp. 1-27
Author(s):  
Jean-Robert Mburano Rwenge ◽  
Franklin Bouba Djourdebbe ◽  
Emmanuel Ekambi Ekambi
Keyword(s):  
Risk Factor ◽  
Condom Use ◽  
Sexual Intercourse ◽  
Health Survey ◽  
Protective Factor ◽  
Multivariate Logistic Regression Analysis ◽  
Demographic And Health Survey ◽  
Main Risk Factor ◽  
Factors Associated ◽  
Service Sectors

Abstract In Cameroon, two-fifths of the population is between the age of 15 and 24. Adolescents and youths are an important social group for the development of the country and the realization of the demographic dividend. The promotion of sexual and reproductive health will enable youth to transform their potential into development. This study aimed to identify the determinants of condom use at last sexual intercourse among single youths, highlight gender differences in the factors associated with condom use and identify the characteristics of youths who were less likely to use condoms. Data were taken from the 2018 Cameroon Demographic and Health Survey. The study sample comprised 1464 single females and 989 single males age 15–24. Multivariate logistic regression analysis was used to test the study hypotheses. Overall, 51% of the female and 66% of the male youths reported using condoms at last sexual intercourse. For both sexes, the protective factor was not having children. Among the females, belonging to the Bamileke or Mbo ethnic groups and delaying first sexual intercourse were also protective, while working in the modern or service sectors was the main risk factor. Among male youths, residing in households whose heads had a higher educational level was protective and household poverty was the main risk factor. These findings support Cameroon’s multi-sectoral approach to HIV/AIDS prevention among youths, and emphasize the importance of involving parents, teachers and youths in prevention strategies.

scholarly journals Peritoneal dialysis - associated peritonitis during treatment with continuous ambulatory peritoneal dialysis

2019 ◽  
pp. 47-52
Author(s):  
M. Malasaiev ◽  
I. Dudar ◽  
A. Shymova
Keyword(s):  
Risk Factor ◽  
Peritoneal Dialysis ◽  
Infectious Complications ◽  
First Year ◽  
Significant Progress ◽  
Main Risk Factor ◽  
Common Cause ◽  
Hemodialysis Treatment ◽  
Methodological Approaches ◽  
Peritoneal Function

 Infections associated with peritoneal dialysis (infection of the catheter, tunnel infection and peritonitis) are the most common complications of this method. Despite significant progress in the methodological approaches to the prevention, diagnosis and treatment of PD associated infections, peritonitis remains the main risk factor for mortality in PD patients (up to 6%) and plays a significant role in more than 1/6 of the deaths associated with non-infectious complications such as cardiovascular and / or cerebrovascular disease. Besides, PD-associated infections are the most common cause of loss of peritoneal function and the patients’ transition to hemodialysis treatment. About 5% of PD patients are converted to hemodialysis treatment in the first year after postponed peritonitis.

THE COURSE OF MYOCARDIAL INFARCTION IN PATIENTS OF YOUNG AGE WITH ARTERIAL HYPERTENSION

2021 ◽  
Vol 2 (5) ◽  
pp. 17-19
Author(s):  
Latif Akhmedov ◽  
Keyword(s):  
Myocardial Infarction ◽  
Risk Factor ◽  
Essential Hypertension ◽  
Cardiovascular Diseases ◽  
Life Expectancy ◽  
Arterial Hypertension ◽  
Young Age ◽  
Main Risk Factor

Arterial hypertension (AH) is the main risk factor (RF) in the development of cardiovascular diseases worldwide. Almost 95% of patients have essential hypertension. In the structure of mortality from various cardiovascular diseases, including AH, 54% is myocardial infarction (MI). Currently, the widespread prevalence of AH and MI among the labor-capable population, early disability, reduced life expectancy, and low adherenceto treatment are of concern.Keywords: arterial hypertension, myocardial infarction, young age, risk factor

scholarly journals Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Zhiyong Wang ◽  
Victoria H. Wu ◽  
Michael M. Allevato ◽  
Mara Gilardi ◽  
Yudou He ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Poor Prognosis ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Model System ◽  
Main Risk Factor ◽  
Common Cancer ◽  
Immunocompetent Mice

AbstractHead and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited activity (≤20%) in HNSCC, highlighting the need to identify new therapeutic options. For this, mouse models that accurately mimic the complexity of the HNSCC mutational landscape and tumor immune environment are urgently needed. Here, we report a mouse HNSCC model system that recapitulates the human tobacco-related HNSCC mutanome, in which tumors grow when implanted in the tongue of immunocompetent mice. These HNSCC lesions have similar immune infiltration and response rates to anti-PD-1 (≤20%) immunotherapy as human HNSCCs. Remarkably, we find that >70% of HNSCC lesions respond to intratumoral anti-CTLA-4. This syngeneic HNSCC mouse model provides a platform to accelerate the development of immunotherapeutic options for HNSCC.

scholarly journals Prevalence and causes of iron deficiency anemias in infants aged 9 to 12 months in Estonia

Medicina ◽  
2007 ◽  
Vol 43 (12) ◽  
pp. 947 ◽  
Author(s):  
Neve Vendt ◽  
Heli Grünberg ◽  
Sirje Leedo ◽  
Vallo Tillmann ◽  
Tiina Talvik
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Mean Corpuscular Volume ◽  
Ferritin Level ◽  
Solid Food ◽  
Deficiency Anemia ◽  
Corpuscular Volume ◽  
Main Risk Factor ◽  
Ferritin Concentration

Objective. To investigate the prevalence and causes of iron deficiency anemia in infants aged 9 to 12 months in Estonia. Material and methods. Every second child aged 9–12 months was randomly selected from primary medical centers in seven counties from all over Estonia. A questionnaire concerning eating habits and lifestyle was sent to their parents. Sixty-five percent (n=195) of contacted families agreed to participate in the study. Mean corpuscular volume and hemoglobin, serum ferritin, and soluble transferrin receptor levels were measured in 171 infants. Anemia was defined when hemoglobin level was lower than 105 g/L, and iron deficiency when ferritin level and mean corpuscular volume were lower than 12 µg/L and 74 fL, respectively. Results. The prevalence of iron deficiency was 14.0% and iron deficiency anemia 9.4%. Birthweight less than 3000 g was the main risk factor for iron deficiency (OR=9.4; P<0.0005). Infants fed with breast milk and solid food had lower ferritin concentration (18.5 µg/L, 95% CI 14.0–23.0) than infants fed with formula and solid food (32.8 µg/L, 95% CI 26.6–39) (P<0.005). Conclusion. Iron deficiency anemia is common among 9–12-month-old Estonian infants. The main risk factor for iron deficiency was birthweight less than 3000 g.

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