S258 – Rapid Intracranial Spread of ENT Infection in B-thalassaemia

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P161-P161
Author(s):  
Faiz Tanwee
Keyword(s):  
Retrospective Study ◽  
Blood Transfusion ◽  
Rapid Development ◽  
Tertiary Hospital ◽  
Age Group ◽  
Full Data ◽  
Contributory Factors ◽  
Intracranial Complications ◽  
Spread Of Infection

Objectives 1) To find out the duration of onset of intracranial complications following middle ear and paranasal sinus infection in B-thalassaemia. 2) To find out the contributory factors for such complications. Methods A retrospective study of thalassaemic children who suffered from intracranial complication following ear and sinus infections between Jan '02- Oct '04, was done at a tertiary hospital Male', Maldives. Follow-up data were obtained from National Thalassaemia Centre. Patients' demographic pattern, thalassaemic status, Desferroxamine therapy, duration of the ear/nose symptom, the intracranial complications, the treatment and the outcomes were noted. We didn't include 3 patients, for whom full data were not available. Results We found the records of a series of 5 consecutive patients out of 94 thalassaemic patients which were referred with different ear and nose infections and were treated for intracranial complications. All patients were in the age group of 10–15 years. All were female. Spread of infection from the ear was more common than the spread from sinuses (3 out of 5 patients). The intracranial complications developed in these patients within few days (<5 days) of presentation in the clinic. All of the patients were on regular blood transfusion with desferroxamine therapy but none had spleenectomy. Most common organism found was klebsiella. Conclusions Persistent anaemia, repeated transfusion, iron overload, and hypersplenism are the major contributory factors for frequent infections in thalassaemics. Natural thinning of the bony cortex and remodelling of skull in thalassaemics can be considered as an additional factor for the rapid development of intracranial complications.

scholarly journals Glycaemic Control after Metformin Discontinuation in Diabetic Patients with a Declining Renal Function

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Theresa Leyco ◽  
Davin Ryanputra ◽  
Ray Peh ◽  
Alexphil Ponce ◽  
Chin Meng Khoo
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Body Weight ◽  
Retrospective Study ◽  
Glycaemic Control ◽  
Tertiary Hospital ◽  
Diabetic Patients ◽  
Diabetes Clinic ◽  
Significant Difference

Metformin is contraindicated in diabetic patients with declining renal function. This study examined the glycaemic control in diabetic patients with chronic kidney disease when metformin was discontinued. This was a retrospective study. We screened 2032 diabetic patients who attended the Diabetes Clinic at a tertiary hospital between 1 September 2014 and 30 September 2015. We analyzed the data on 69 patients whom metformin was discontinued due to declining renal function and had a complete 6-month follow-up. There was no significant difference in the HbA1c and body weight at 6-month follow-up compared to baseline after metformin discontinuation. The eGFR was significantly lower at 6-month follow-up compared to baseline. Upon metformin discontinuation, the majority of patients had their diabetes medication uptitrated (in particular insulin or sulphonylurea). Patients with an improved glycaemia at 6-month follow-up had further declined in eGFR compared to patients with worsened glycaemia. 17% of the study patients experienced hypoglycaemia. Upon metformin discontinuation, glycaemic control could be optimised with uptitration but should be balanced against the risk of hypoglycaemia. Further improvement in the glycaemic control might indicate further deterioration in the renal function.

scholarly journals A clinical profile of leprosy patients in a tertiary hospital, Karnataka: a retrospective study

2019 ◽  
Vol 5 (3) ◽  
pp. 615
Author(s):  
Vinay K. Nirvanappa ◽  
Soumya G. Hegde
Keyword(s):  
Retrospective Study ◽  
Major Part ◽  
Health Hazard ◽  
Public Health Problem ◽  
Mycobacterial Infection ◽  
Tertiary Hospital ◽  
Lepromatous Leprosy ◽  
Age Group ◽  
Major Health ◽  
Leprosy Patients

<p class="abstract"><strong>Background:</strong> Leprosy is a chronic mycobacterial infection and is still a major health hazard in India.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective study over 12 years of all cases diagnosed clinically as leprosy in a tertiary hospital at Hassan district, Karnataka. Confirmation of diagnosis was based on slit skin smear and biopsy was done in doubtful cases.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 214 patients, 152 were males and 62 were females. The prevalence was maximum in the age group 21-30 years. Borderline group formed the major part of the spectrum, consisting of 154 (71.96%) patients. Maximum patients 97 (45.3%) were of borderline tuberculoid (BT) leprosy, followed by 59 (27.57%) cases of borderline lepromatous leprosy (BL). 25 (11.68%) cases had tuberculoid leprosy (TT) and 20 (9.34%)cases were of lepromatous leprosy among which 3 were diagnosed as histoid leprosy. 6 patients had pure neuritic leprosy and 4 patients were in relapse.</p><p><strong>Conclusions:</strong> Even though leprosy is eliminated, it continues to be a public health problem in our country. Stricter surveillance for early diagnosis and treatment is needed to eradicate leprosy from India.</p>

scholarly journals Choice of temporary contraception based on client’s demographic status and parity

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Benju Pandit
Keyword(s):  
Retrospective Study ◽  
Contraceptive Method ◽  
Descriptive Analysis ◽  
Tertiary Hospital ◽  
Age Group ◽  
Hospital Record ◽  
Contraceptive Methods ◽  
Contraceptive Service ◽  
Long Acting ◽  
To Receive

Aim: To analyse the demographic factors and parity in women influencing choice of contraceptive methods. Methods: This is a hospital record based retrospective study at Bhaktapur hospital, a tertiary hospital in a span of 6 months from October 2020 to March 2021. Data were collected from medical record and descriptive analysis was done. Results: There were 142 women taking contraceptive service in six months.Implant was the most commonly used method of contraception (48%), followed by the IUCD (26%), Injectable (16%) and OCP (10%). Age group of 20-39 had more acceptance of contraception as compared to adolescent and women above 40. More the parity more usage of long acting reversible contraception was found. Conclusion: The most common contraceptive method used among women was implant. Client having two or more children are more to receive long acting contraception.

scholarly journals Postpartum implanon/nexplanon uptake in a tertiary hospital in West Africa

2019 ◽  
Vol 8 (5) ◽  
pp. 1816
Author(s):  
Kwaku Asah-Opoku ◽  
Kareem Mumuni ◽  
Vincent J. Ganu ◽  
Ali Samba
Keyword(s):  
Retrospective Study ◽  
Family Planning ◽  
Reproductive Health ◽  
Postpartum Period ◽  
Post Partum ◽  
Unmet Need ◽  
Tertiary Hospital ◽  
Age Group ◽  
High Uptake ◽  
First Time

Background: The postpartum period is viewed as an opportune period for uptake of contraception. Ghana has an unmet need for family planning of 30%. This study sought to determine the postpartum Implanon/Nexplanon uptake among women at a tertiary hospital.Methods: This was a retrospective study that analysed 391 Implanon/Nexplanon insertions between 2012 and 2015 at the reproductive health and family planning unit at the Korle-Bu teaching hospital.Results: Almost 69% (391/565) of all Implanon/Nexplanon insertions conducted between 2012 and 2015 were conducted in the postpartum period. Out of these postpartum insertions, 2.3% were done in the immediate postpartum period, 27.6% were done during the interval postpartum period and 70.1% were in the delayed postpartum period. Age and implant insertion status (first time ever or continuing) were significant determinants of postpartum Implanon/Nexplanon insertions. Compared to women less than 20 years of age, women in the age group 20-29 and 30-39 were 76% (AOR=0.24, CI=0.62-0.97) and 80% (AOR=0.20, CI=0.05-0.86) respectively less likely to have postpartum Implanon/Nexplanon  insertions done. Continuing users of implant insertions were 45% (AOR=0.55, CI=0.37-0.82) less likely to have post-partum Implanon/Nexplanon insertions done compared to first ever users.Conclusions: There is a high uptake of postpartum Implanon/Nexplanon use among patients who receive implant insertions at the Korle-Bu Teaching Hospital. However immediate postpartum Implanon/Nexplanon insertions are low. There is the need to educate women and couples on the benefits of immediate postpartum implant insertion to avoid rapid repeat pregnancies.

scholarly journals Pregnancy outcome in patients with fibroid: a retrospective study

2020 ◽  
Vol 9 (11) ◽  
pp. 4428
Author(s):  
Bintu H. Dadhania ◽  
Shital T. Mehta ◽  
Pushpa A. Yadava ◽  
Bina M. Raval ◽  
Bhavi S. Shah ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Preterm Labour ◽  
Care Center ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Normal Vaginal Delivery ◽  
Delivery Mode ◽  
Age Group ◽  
Antenatal Period

Background: Fibroids are benign smooth muscle cell tumour of the uterus. In some patients of pregnancy associated with fibroid, it does not affect the outcome of pregnancy. On the other hand, various complications have been reported. The aim of our study was to evaluate the outcome in antenatal women with fibroids.Methods: This retrospective study was conducted at tertiary care center, obstetrics & gynecology department over a period of eighteen months between June 2018 to November 2019. Total 26 pregnant patients with >3 cm fibroid was included in the study. They were followed during antenatal period. Maternal age, parity, size of fibroid, complications during pregnancy, labour, and delivery, mode of delivery and indications of cesarean section were noted.Results: Out of 26 patients, 15 (57.6%) were between 26-30 years of age group and 16 (61.53%) were multigravidas. Normal vaginal delivery occurred in 8 (33.33%), while 16 (66.66%) delivered by caesarean section. There were 9 (34.61%) patients who had no complication whereas 17 (65.38%) had some complication. Pain was present in 8 (30.76%). PROM and preterm labour were present in 3 (18.75%) and 5 (19.23%) respectively. PPH was present in 2 (7.69%).Conclusions: Pregnant patients who have fibroids are to be carefully screened in the antenatal period, so as to have a regular follow up. The widespread use of ultrasonography has facilitated diagnosis and management of fibroids in pregnancy. The site and size of fibroid is very important to predict its effect on pregnancy.

scholarly journals Outcomes and Complications of Sutured Scleral-Fixated Foldable Intraocular Lens Implantation: A Retrospective Study of 5-Year Follow-Up

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Ting Yu ◽  
Mengting Yu ◽  
Wenjie Wu ◽  
Xinna Wu ◽  
Suzhen Xiao ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Intraocular Lens ◽  
Tertiary Hospital ◽  
Long Term Outcomes ◽  
Iol Implantation ◽  
Minimum Angle ◽  
The Mean ◽  
Iol Dislocation

Purpose. To evaluate long-term outcomes and complications of sutured scleral-fixated foldable intraocular lens (IOL) implantation. Design. Retrospective study. Methods. Patients who underwent sutured scleral-fixated foldable IOL implantation using 10-0 polypropylene suture were followed up for at least 5 years at one Chinese tertiary hospital and two primary hospitals. Results. 52 eyes among 48 patients (35 male and 13 female) were evaluated. The mean age (years) was 50.27 ± 20.08 (range: 6 to 81). The mean postoperative follow-up time (months) was 79.70 ± 18.84 (range: 60 to 121). The mean best-corrected visual acuity (BCVA) improved from 0.83 ± 0.69 logarithm of the minimum angle of resolution (logMAR) at baseline to 0.50 ± 0.45 logMAR at the last follow-up visit. There was improved or unchanged BCVA in 44 eyes (84.62%) and reduced BCVA in 8 eyes (15.38%). Mild intraoperative intravitreal hemorrhage was observed in 3 eyes (5.77%). Early postoperative complications included transient elevated intraocular pressure (IOP) in 5 eyes (9.62%) and hypotony in 1 eye (1.92%). Secondary epimacular membrane occurred in 5 eyes (9.62%) and retinal detachment (RD; 3 years postsurgery), subconjunctival suture knot exposure (5 years postsurgery), and persistent elevated IOP (in a GRAVES patient) occurred in 1 eye (1.92%) each. No suture erosion or breakage nor IOL dislocation was observed. No visually threatening IOL tilt or decentration was reported in any patient. Conclusion. Sutured scleral-fixated foldable IOL implantation demonstrated satisfactory long-term outcomes and rare suture-related complications. This technology was safe and did not require complicated equipment and is of considerable interest in the setting of aphakia without adequate capsule support.

scholarly journals A SURVEY ON RHINO - ORBITAL - CEREBRAL MUCORMYCOSIS PATIENTS - A POST COVID OCCURRENCE IN TERTIARY HOSPITAL

2021 ◽  
Vol 9 (07) ◽  
pp. 1068-1073
Author(s):  
Dhinakaran N. ◽  
◽  
Arul Sundaresh Kumar L. ◽  
Karthikeyan B.M. ◽  
Monisha R.M ◽  
...  
Keyword(s):  
Case Reports ◽  
Secondary Infection ◽  
Demographic Data ◽  
Age Groups ◽  
Tertiary Hospital ◽  
Age Group ◽  
Nasal Sinus ◽  
Age Range

With increasing case reports of Rhino - Orbital - Cerebral Mucormycosis, a secondary infection to Post COVID condition, the present study aimed to find the occurrence of Mucormycosis across various age groups, its presence among vaccinated population, relation between hyperglycemia and mucormycosis, site of involvement of nasal/ sinus mucormycosis and the Culture based genus classification of fungal Mucormycosis. A total number of 250 patients diagnosed with either Confirmed/ Suspected Mucormycosis, a Post COVID infection were included in the study. For all the patients, their demographic data, comorbities, vaccination details, imaging findings and follow up information were obtained and statistically analyzed for the study. The results show that: a) A major of 36.4% of mucormycosis patients were found between the age range of 51 - 60 years. B) Vaccinated population is less vulnerable to COVID and its secondary infection - Mucormycosis. C) Site of involvement of Nasal/ Sinus Mucormycosis is found as a Combined Maxillary+Ethmoid+orbit involvement in 80.8% followed by Ehtmoidal involvement and palatal involvement. D) Presence of diabetes mellitus was present among 93.2% of the participants and E) The genus classification shows the occurrence of Rhizopus Arrhizus was the cause for mucormycosis found in many of the culture based fungal infection among the Post COVID patients involved in the study. The study concludes that patients treated for COVID in the age group of 30 years to 70 years are more vulnerable to acquire Mucormycosis. Glycemic control among the COVID treatment patients will grossly prevent the occurrence of Mucormycosis infection.

scholarly journals Blood transfusion and lung surgeries in pediatric age group: A single center retrospective study

2020 ◽  
Vol 23 (2) ◽  
pp. 149
Author(s):  
AhmedS Elgebaly ◽  
SamehM Fathy ◽  
MonaB Elmorad ◽  
AymanA Sallam
Keyword(s):  
Retrospective Study ◽  
Blood Transfusion ◽  
Age Group ◽  
Pediatric Age ◽  
Single Center ◽  
Pediatric Age Group ◽  
Group A

scholarly journals Thyroid Swellings Undergoing Thyroidectomy in a Tertiary Hospital of Nepal: A Retrospective Study of Distribution and Prevalence of Malignancy

2021 ◽  
Vol 1 (2) ◽  
pp. 27-33
Author(s):  
Mudit Gupta ◽  
Rajeev Kumar Mahaseth ◽  
Sajish Khadgi ◽  
Asmita Shrestha ◽  
Neeti Bhat ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Thyroid Nodule ◽  
Papillary Carcinoma ◽  
Thyroid Nodules ◽  
Benign Lesion ◽  
Needle Aspiration ◽  
Tertiary Hospital ◽  
Common Finding ◽  
Age Group ◽  
Histopathological Evaluation

Introduction: Thyroid nodules brought to a hospital are checked for cancer. A post-operative histological examination is a gold standard for diagnosing thyroid lesions. Treatment is aided by a prior understanding of the disease’s underlying pattern. Objective: A retrospective study was done to determine the prevalence and distribution of malignancy in suspicious thyroid nodules. Methods: The study was conducted at Ganesh Man Singh Memorial Academy of ENT- Head and Neck studies from August 2017 to March 2020. All the subjects (n=183) presenting with a thyroid nodule and who had post-operative histopathological evaluation available were recruited in the study. The proportion and percentage of findings of Fine Needle Aspiration Cytology (FNAC) and histopathological evaluation were done. The distribution of histopathological observation was also analyzed in terms of age group and gender. Results: The mean age of study participants was 40.23 ± 13.77 years (n=183). The predominance of women was notable. In about 98 (53.55%) of the patients who underwent thyroidectomy, a benign lesion was found, but the most common finding was papillary carcinoma (40.98%). In the age group below 50 years, papillary carcinoma was most common. Among people older than 50, colloid goiter was more common. Follicular and medullary carcinomas were only observed in female participants. Gender did not appear to be associated with malignancy (p=0.99). Follicular adenomas were noted to have the youngest mean age. Conclusions: We observed a high prevalence of malignancy, particularly papillary carcinoma in clinically suspected thyroid nodules of a tertiary hospital in Nepal. Keywords: Colloid Goiter; malignancy; papillary carcinoma; thyroid cancer; thyroid nodule.

Use of rivaroxaban in patients attending a hematology unit in clinical practice

2019 ◽  
Vol 15 (5) ◽  
pp. 347-353
Author(s):  
Olga Gavín Sebastián ◽  
Macarena Izuzquiza Fernández ◽  
Raquel Martínez Fernández ◽  
Luis Palomera Bernal
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Practice ◽  
Retrospective Study ◽  
Venous Thromboembolism ◽  
Intracranial Hemorrhage ◽  
Major Bleeding ◽  
Tertiary Hospital ◽  
Thromboembolic Events ◽  
Medication Persistence

Aim: To determine drug persistence and rates of events among patients treated with rivaroxaban in a hematology unit. Methods: Retrospective study of patients that started treatment with rivaroxaban, in the hematology unit of a tertiary hospital. Results: A total of 161 patients were included, of whom 83.9% had atrial fibrillation and 11.2% venous thromboembolism, and 76.4% of patients were taking rivaroxaban 20 mg, 22.4% 15 mg and 1.2% 10 mg. After a follow-up of 1.8 ± 1.1 years, only four patients (2.5%) discontinued treatment. Rates of thromboembolic events, major bleeding/clinically relevant nonmajor bleeding and intracranial hemorrhage were 1.1, 2.8, 0.3 events per 100 patient-years, respectively. Conclusion: In patients attended in a hematology unit, medication persistence was high, and the incidence of outcomes low.

Sign in / Sign up

Export Citation Format

Share Document