Artificial rearing of piglets: the administration of two sources of immunoglobulins after birth

ABSTRACTSixty Landrace × Large White piglets were removed from their mothers at birth and allocated to one of five treatments. Treatment A piglets were controls and did not receive any form of passive immunity after birth. Treatment B piglets were given by intraperitoneal injection 20 ml equine serum derived from horses previously hyperimmunized against porcine pathogens. Treatment C piglets received the same equine serum given orally. Treatment D piglets were given 20 ml pooled pig plasma by intraperitoneal injection. Treatment E piglets received the same pig plasma given orally. All piglets were reared to 2 weeks of age in an artificial-rearing device and were automatically fed a liquid diet every hour. Overall survival to 2 weeks of age was 90% (54/60) but treatment did not affect survival. The overall survival after 6 weeks of age was 47% (22/47) deaths being due to a variety of systemic disorders. Overall daily gain to 2 weeks of age was 143 g/day and the food/gain ratio was 0·88. Treatment did not affect performance. The concentrations of immunoglobulin class G (IgG) in the blood were measured at 42, 49 and 56 days of age. There were no differences between the treatment groups in IgG concentrations.

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Improving growth performance of finisher pigs with high fat diets

Animal Production Science ◽

10.1071/ea08243 ◽

2009 ◽

Vol 49 (3) ◽

pp. 262 ◽

Cited By ~ 6

Author(s):

C. L. Collins ◽

A. C. Philpotts ◽

D. J. Henman

Keyword(s):

Growth Performance ◽

Dietary Fat ◽

Feeding Strategy ◽

Average Weight ◽

Large White ◽

Gain Ratio ◽

Fat Diets ◽

Supplemental Fat ◽

Daily Gain ◽

Entire Male

A total of 1296 pigs (Large White × Landrace) were selected at 16 weeks of age and used to investigate the effects of supplemental dietary fat concentration on finisher growth performance. Pigs were selected at an average weight of 64.0 kg and allocated to a 2 × 6 factorial experiment with the respective factors being sex (entire male and female) and supplemental dietary fat concentration (1, 2, 3, 4, 5 and 6% added tallow). All pigs were offered the respective diets ad libitum from 16 weeks of age through to slaughter at 21 weeks of age. Over the entire 5-week period, feed : gain ratio improved linearly with increasing supplemental fat concentration (P < 0.001), reducing from 2.60 to 2.44 with an increase in dietary fat concentration from 1 to 6%. Improvements in daily gain were more pronounced during the initial 14-day feeding period, increasing linearly (P = 0.002) from 844 g/day (1% fat) to 942 g/day (6% fat). Carcass weight also improved linearly (P = 0.009), increasing from 74.1 kg (1% fat) to 75.8 kg (6% fat). A greater response was observed in the males, with an increase in supplemental fat concentration from 1 to 6% improving daily gain by 7%, reducing the feed: gain ratio from 2.55 to 2.31 and improving profit per pig by AU$4.17. The effects of increasing dietary fat concentration were more moderate in females, with potential profit increases of AU$1.47. These results suggest that adding up to 6% supplemental fat to finisher diets improves profit under Australian conditions, with the benefits greater in male than female pigs. The economic impact of such a feeding strategy will, however, depend on the pig’s genetic propensity for fat deposition and the pricing system in which the pigs are sold.

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Nucleotide Supplementation to Whole Milk Has Beneficial Effects on Post-Weaning Holstein Calf Performance

Animals ◽

10.3390/ani11010218 ◽

2021 ◽

Vol 11 (1) ◽

pp. 218

Author(s):

Yousef Abbaslou ◽

Davood Zahmatkesh ◽

Ehsan Mahjoubi ◽

Mehdi Hossein Yazdi ◽

Hamed Beiranvand ◽

...

Keyword(s):

Body Weight ◽

Average Daily Gain ◽

Free Access ◽

Treatment Groups ◽

Beneficial Effects ◽

Positive Effects ◽

Whole Milk ◽

Calf Performance ◽

Daily Gain ◽

Fecal Score

The positive effects of nucleotide (NU) supplementation in milk replacer have been elucidated in infants and in dairy calves; however, NU addition to whole milk has not been evaluated previously. This study aimed to assess NU supplementation in the whole milk on calf growth and health. Thirty Holstein calves (body weight: 39.1 ± 1.0 kg; 3 d after birth) were randomly assigned to the following treatments: whole milk without any supplementation (NU0), whole milk + 0.5 g/d added a NU-containing supplement to whole milk (NUCS0.5), and whole milk + 1 g/d added a NU-containing supplement to whole milk (NUCS1). Calves were weaned at d 55 and stayed on study until d 75. Calves had free access to feed and water throughout the study. Dry matter intakes (DMI) were similar among treatments (p > 0.05) during the pre-weaning period; however, increasing NU resulted in a linear (p < 0.05) increase in DMI during the post weaning period (2158, 2432, and 2518 g/d for NU0, NUCS0.5, and NUCS1, respectively). Treatments did not affect body weight (BW) at the first and second month of study, but final BW linearly increased as NU was added (87.1, 90.6, and 95.4 kg for NU0, NUCS0.5, and NUCS1, respectively). Neither pre-weaning average daily gain nor post-weaning average daily gain was affected by treatments; accordingly, feed efficiency was similar among treatment groups. Days with loose fecal score were linearly decreased as NU was added to whole milk during the first month of life, while the fecal score did not differ among treatments until the end of the study. No difference was observed in the skeletal growth of calves in the current study. Therefore, it can be concluded that NU supplementation in the whole milk has some beneficial effects on calf performance in terms of final BW, post-weaning DMI, and less days with loose feces.

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THE EFFECTS OF LEVELS OF ISOLATION, OR VARIETAL DIFFERENCES IN, HIGH FIBRE HULL FRACTION OF LOW GLUCOSINOLATE RAPESEED MEALS ON RAT OR PIG PERFORMANCE

Canadian Journal of Animal Science ◽

10.4141/cjas78-093 ◽

1978 ◽

Vol 58 (4) ◽

pp. 743-752 ◽

Cited By ~ 14

Author(s):

J. J. KENNELLY ◽

F. X. AHERNE ◽

A. J. LEWIS

Keyword(s):

Feed Intake ◽

Average Daily Gain ◽

Rapeseed Meal ◽

Sprague Dawley ◽

Crude Fibre ◽

Gain Ratio ◽

Sprague Dawley Rats ◽

Significant Difference ◽

Pig Performance ◽

Daily Gain

Forty-eight crossbred pigs of average initial weight 21 kg were fed 10% Tower rapeseed meal (RSM) and 10% Candle RSM as partial replacements for soybean meal (SBM). Diets were formulated to be isocaloric. Pigs fed the SBM diet consumed less feed, gained significantly (P < 0.01) faster and were more efficient at converting feed to gain than those fed the RSM diets. Performance of pigs fed Candle RSM was not significantly different to that obtained with Tower RSM. In a second experiment, dehulled Tower RSM and Tower RSM hulls were mixed in amounts to produce RSM with crude fibre levels of 6.8, 10.8, 13.5 and 15.8%. The simulated RSM and Tower and Candle RSM were used to completely replace SBM in the diets of weanling (75 g) Sprague-Dawley rats. Rats fed SBM had significantly (P < 0.05) higher average daily gain (ADG) than those fed Tower or Candle RSM, or diets containing the rapeseed meats. There was no significant (P < 0.05) difference in ADG, feed intake or feed to gain ratio of rats fed either Tower or Candle RSM. Feed intake, feed to gain ratio and fecal volatile fatty acid concentrations increased while average daily gain decreased with increasing level of hulls in simulated RSM diets. There was no significant difference (P < 0.05) in thyroid weight between rats fed SBM, Tower RSM or Candle RSM.

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Influence of energy and protein concentration in the diet on the performance of growing pigs 2. Differing nutrient density at a constant energy: protein ratio

Animal Science ◽

10.1017/s000335610000026x ◽

1972 ◽

Vol 14 (1) ◽

pp. 47-55 ◽

Cited By ~ 8

Author(s):

G. A. Lodge ◽

M. E. Cundy ◽

R. Cooke ◽

D. Lewis

Keyword(s):

Growth Rate ◽

Live Weight ◽

Fat Content ◽

Growing Pigs ◽

Feed Conversion ◽

Large White ◽

Protein Ratio ◽

Treatment Groups ◽

Nutrient Density ◽

Amino Acid Balance

SUMMARYForty-eight gilts by Landrace sires on Large White × Landrace females were randomly allocated to eight pens and within pens to six treatment groups involving three diets and two levels of feeding from 23 to 59 kg live weight. All diets were formulated to have approximately the same ratio of digestible energy to crude protein (160 kcal DE/unit % CP) but different energy and protein concentrations: (A) 3500 kcal/kg DE and 21 % CP, (B) 3150 kcal/kg DE and 19% CP, and (C) 2800 kcal/kg DE and 17% CP. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. The levels of feeding were such that the lower level of diet A allowed an intake of energy and protein similar to the higher level of diet B, and the lower level of B was similar to the higher level of C.On the lower level of feeding, growth rate, efficiency of feed conversion and carcass fat content increased linearly with each increment in nutrient concentration; on the higher level of feeding growth rate and EFC increased from diet C to B but not from B to A, whereas carcass fat content increased linearly with diet from the lowest to the highest concentration. There was a non-significant tendency for the higher density diets at a similar level of nutrient intake to give better EFC and fatter carcasses than the lower density diets.

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The influence of intake of dietary energy in pregnancy and lactation upon sow productivity

The Journal of Agricultural Science ◽

10.1017/s0021859600014672 ◽

1968 ◽

Vol 71 (2) ◽

pp. 215-222 ◽

Cited By ~ 19

Author(s):

F. W. H. Elsley ◽

R. M. MacPherson ◽

I. McDonald

Keyword(s):

Daily Intake ◽

Dietary Energy ◽

Large White ◽

Treatment Groups ◽

Daily Energy ◽

Reproductive Life ◽

Pregnancy And Lactation ◽

Daily Intakes ◽

Practical Implications ◽

In Pregnancy

SUMMARYFifty-two Large White gilts, arranged in thirteen groups of four litter sisters, were allocated at mating to one of four treatment groups. These treatments, arranged as a 2 × 2 factorial, allowed daily energy intakes in pregnancy of 8·3 Meal (H(e)) or 5·2 Meal (L(e)) and of average daily intake during lactation of 20 Meal (h(e)) or 13·8 Meal (m(e)). Daily intakes of protein, minerals and vitamins were similar for all treatments. There were no consistent differences in health or breeding regularity between the treatments.The H(e) sows had a net gain in pregnancy 22 kg greater than the L(e) sows. Feeding the higher level in lactation (h(e) resulted in a reduced sow weight loss during lactation of 20, 12 and 10 kg in the first, second and third parities respectively, as compared with the m(e) sows. There were no consistent effects on the numbers of pigs born apart from the first litter in which L(e) sows produced significantly larger litters at birth. The higher energy intakes in pregnancy and lactation led to very similar increases in the weights of the piglets, of the order of 0.1 kg at birth, 0.4 kg at 3 weeks of age, and 1.1 kg at 8 weeks of age. Sowsgiven the same overall energy intake throughout their reproductive life (H(e) m(e), L(e) h(e)) at the end of the third litter had similar live weights and had produced a similar total weight of weaned pigs. The practical implications of these results are discussed.

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COMPARAISON DE DIVERSES METHODES DE CASTRATION ET DE STERILISATION DES AGNEAUX: I. INFLUENCE DE CES METHODES SUR LA CROISSANCE, L’EFFICIENCE ALIMENTAIRE, LE RENDEMENT A L’AHATTAGE ET LA RENTABILITE

Canadian Journal of Animal Science ◽

10.4141/cjas71-078 ◽

1971 ◽

Vol 51 (3) ◽

pp. 579-589 ◽

Cited By ~ 1

Author(s):

J. M. BAILLARGEON ◽

J. P. LEMAY ◽

W. B. HOLTMANN ◽

L. A. CHARETTE

Keyword(s):

Feed Efficiency ◽

Intramuscular Injection ◽

Cadmium Chloride ◽

Complete Removal ◽

Chemical Methods ◽

Treatment Groups ◽

Dressing Percentage ◽

Breeding Groups ◽

Physical And Chemical ◽

Daily Gain

An experiment was conducted to compare various physical and chemical methods of castration of lambs at 15 and 60 days of age. Their effects on body growth, feed efficiency, dressing percentage and profitability were studied. At birth 100 lambs were divided among the 16 different treatments according to sex and the following breeding groups: Suffolk, North Country Cheviot, two-breed cross and three-breed cross. The different methods of castration were: complete removal of the testicles, Burdizzo, elastrator and partial castration. The sterilization methods consisted of intramuscular, intratesticular and intraveinous injection of cadmium chloride. All lambs were weaned at 30 days of age and placed in individual pens. They were subjected to similar environmental conditions and shipped to slaughter at approximately 45 kg body weight. Significant differences were observed among breeds, sexes and the various castration methods for daily gain, feed efficiency, days required to reach market and profitability. Age at castration did not have any important effect ort the variables measured. Superior gains, feed efficiency and profitability were observed for the partially castrated group, for the lambs that received an intramuscular injection of cadmium chloride and for the non-castrated males. All treatment groups involving males were superior to the females for the characters studied except for dressing percentage.

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The effect of restricted suckling and non-suckling systems on dairy cow and calf behaviour

Proceedings of the British Society of Animal Science ◽

10.1017/s1752756200593247 ◽

1996 ◽

Vol 1996 ◽

pp. 128-128

Author(s):

J. K. Margerison ◽

C. J. C. Phillips ◽

T. R. Preston

Keyword(s):

Dairy Cows ◽

Dairy Cow ◽

Artificial Rearing ◽

Treatment Groups ◽

Cow Calf

Artificial rearing necessitates stressful cow-calf separation (Lefcourt and Elsasser, 1995; Hopster et al, 1995) and precipitates cross-suckling (Lidfors, 1993). Thus, suckling systems may improve the welfare of cows and calves, by alleviating 'stressful' cows-calf separation and satiating suckling motivation. The aim of this experiment was to compare behaviour in cows and calves in restricted suckling and non-suckling systems.Thirty six multiparous dairy cows and calves were divided at 4 days postpartum into three groups. The treatment groups were; non-suckled (NS) cows with calves artificially reared (AR), cows suckled by their own calf (RSM) and cows suckled by a foster calf (RSF). Suckling took place for 15 minutes following mechanical milking only.

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Interactions between weaning age, weaning weight, sex, and enzyme supplementation on growth performance of pigs

Australian Journal of Agricultural Research ◽

10.1071/ar01197 ◽

2002 ◽

Vol 53 (8) ◽

pp. 939 ◽

Cited By ~ 10

Author(s):

F. R. Dunshea ◽

D. K. Kerton ◽

P. D. Cranwell ◽

R. G. Campbell ◽

B. P. Mullan ◽

...

Keyword(s):

Feed Intake ◽

Feed Conversion ◽

Large White ◽

Weaning Weight ◽

Exogenous Enzyme ◽

The Third ◽

Main Effect ◽

Weaning Age ◽

Enzyme Supplementation ◽

Daily Gain

Digestive capacity of early-weaned pigs may be insufficient to fully digest many ingredients currently used in weaner diets. The aim of this experiment was to determine whether an exogenous enzyme preparation with broad carbohydrase activity could benefit pigs that developmentally might be immature at weaning, especially with regard to gastrointestinal development. Eighty Large White × Landrace pigs were used in a 2 × 2 × 2 × 2 factorial experiment with the factors being: weaning age (14 or 24 days), weaning weight (heavy or light), sex (boar or gilt), and dietary Biofeed Plus CT (0 or 500 μg/g) which contained fungal xylanases, pentosanases and β-glucanases. Pigs were housed individually and given a wheat-based (550 g/kg) diet containing 15.0 MJ DE and 15.9 g lysine/kg on an ad libitum basis for 21 days. The diet also contained 50 g/kg of soybean meal and 50 g/kg of lupin (Lupinus�angustifolius) kernels. The liveweights of heavy (H) pigs weaned at 24 or 14 days and light pigs (L) weaned at 24 or 14 days were 7.9 and 5.3 and 5.2 and 3.9 kg, respectively. Pigs weaned at 14 days grew slower (157 v. 345 g/day) than those weaned at 24 days, although there was a suggestion of an interaction between age and weight at weaning (P = 0.081). Thus, H and L pigs weaned at 14 days grew at 148 and 166 g/day, whereas H and L pigs weaned at 24 days grew at 374 and 315 g/day, respectively. Although there was no main effect of enzymes on daily gain (248 v. 254 g/day, P = 0.80), feed intake (278 v. 284 g/day, P = 0.79), or feed conversion ratio (1.19 v. 1.25, P�=�0.35), there were interactions with weaning age on daily gain (P = 0.050) and feed intake (P = 0.060). Pigs weaned at 14 days grew slower (176 v. 138 g/day) and ate less (206 v. 174 g/day), whereas pigs weaned at 24 days grew faster (321 v. 369 g/day) and ate more (351 v. 394 g/day), when supplemented with enzymes. During the third week after weaning there were interactions between dietary enzymes and sex (P = 0.060) and dietary enzymes and age (P = 0.023) on daily gain. Thus, pigs weaned at 24 days and supplemented with Biofeed Plus CT grew more quickly during the third week (559 v. 460 g/day), whereas the converse was true for pigs weaned at 14 days (286 v. 334 g/day). Also, enzyme-supplemented boars grew better over this period (457 v. 371 g/day), whereas the converse was true for gilts (388 v. 423 g/day). In conclusion, these data clearly indicate that the greatest determinant of post-weaning performance under the present conditions was the age of the pigs at weaning. Dietary enzyme supplementation appeared most efficacious in boars weaned at an older age, although benefits did not become apparent until 2 weeks after weaning.

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Survival and mortality of elderly men with localized prostate cancer managed with primary androgen deprivation therapy or by primary observation

10.21203/rs.2.13155/v3 ◽

2020 ◽

Author(s):

Heikki Seikkula ◽

Peter J. Boström ◽

Karri Seppä ◽

Janne Pitkäniemi ◽

Nea Malila ◽

...

Keyword(s):

Prostate Cancer ◽

Overall Survival ◽

Androgen Deprivation Therapy ◽

Androgen Deprivation ◽

Localized Prostate Cancer ◽

Curative Treatment ◽

Entire Study ◽

Treatment Groups ◽

Age Cohorts ◽

Cancer Aggressiveness

Abstract Background: Androgen deprivation therapy (ADT) remains a primary treatment for localized prostate cancer (PCa) even though there is no evidence that its use is beneficial in the absence of curative treatment.Methods: Men aged ≥70 years (n = 16534) diagnosed with localized PCa from 1985 to 2014 and managed either with primary observation or ADT in the absence of curative treatment were included. The cases were identified from the population-based Finnish Cancer Registry. We estimated the standardized mortality ratios (SMR) for overall mortality by treatment group. We determined the relative risk (RR) of PCa-specific mortality (PCSM) and other-cause mortality between the two treatment groups. Survival was determined using the life table method. Two age groups (70–79 years and ≥80 years) and three calendar time cohorts (1985–1994, 1995–2004, and 2005–2014) were compared following adjustment of propensity score matching between the treatment groups with four covariates (age, year of diagnosis, educational level, and hospital district). Follow-up continued until death or until December 31, 2015. Results: Patients in the observation group had lower overall SMRs than those in the ADT group in both age cohorts over the entire study period. PCSM was higher in men aged 70–79 years undergoing primary ADT compared to those managed by observation only (RR: 1.70, 95% confidence interval [CI]: 1.29–2.23 [1985–1994]; RR 1.55, 95% CI: 1.35–1.84 [1995–2004]; and RR 2.71, 95% CI: 2.08–3.53 [2005–2014]); p = 0.005 for periodic trend. A similar trend over time was also observed in men aged >80 years; (p for age–period interaction = 0.237). Overall survival was also higher among men in their 70’s managed by observation compared to those undergoing ADT.Conclusions: Primary ADT within four months period from diagnosis is not associated with improved long-term overall survival or decreased PCSM compared to primary conservative management for men with localized PCa. However, this observational study’s conclusions should be weighted with confounding factors related to cancer aggressiveness and comorbidities.

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Glucocorticoid Receptor Agonists to Improve the Productivity and Health of Early-Weaned Pigs: What Is the Best Method of Delivery?

Animals ◽

10.3390/ani10071124 ◽

2020 ◽

Vol 10 (7) ◽

pp. 1124

Author(s):

Hailey Wooten ◽

Hwanhee Kim ◽

Amanda R. Rakhshandeh ◽

Anoosh Rakhshandeh

Keyword(s):

Body Weight ◽

Glucocorticoid Receptor ◽

Low Dose ◽

Average Daily Gain ◽

Feed Ratio ◽

High Dose ◽

Suitable Alternative ◽

Treatment Groups ◽

Daily Gain ◽

All Treatment

The purpose of the current study was to determine the best method of delivery for glucocorticoid receptor agonist (GRA) treatment. A total of 167 Pig Improvement Company (PIC) piglets (body weight (BW) 7.35 ± 1.24 kg) were weaned at 25.0 ± 0.81 days of age and randomly assigned to 14 treatment groups based on a 2 × 7 factorial arrangement with sex (gilts vs. barrows), in-feed antibiotic (ANT; 110 mg/kg in-feed tylosin), repeated intramuscular (I.M.) injection of GRA (two injections, 0.2 mg/kg BW dexamethasone (DEX)), low dose in-feed GRA (LF, 2.5 mg/kg diet DEX ), high dose in-feed GRA (HF, 5 mg/kg diet DEX), low dose in-water GRA (LW, 0.8 mg/L DEX ), high dose in-water GRA (HW, 1.6 mg/L DEX ), and no treatment control (CON) as the main factors. Body weight and feed intake were measured daily from days 0 to 7 and weekly from days 7 to 28 post-weaning. The interaction effect for average daily gain (ADG) was significant with gilts performing better in the I.M., ANT, and LF groups (p = 0.05). All treatment groups, with the exception of the HW group, had a higher ADG than the CON group. Gilts in the I.M., LF, and HF groups had the highest ADG compared to other treatment groups (p ≤ 0.05). Sex and the interaction between sex and treatments had no effect on the gain-to-feed ratio (G:F; p ≥ 0.21). All treatment groups had a higher G:F than the CON group (p ≥ 0.04). These results suggest that the low-dose, in-feed GRA treatment is the best GRA delivery method and is a suitable alternative to in-feed sub-therapeutic antibiotics.

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