The longitudinal associations between trajectory of and quantity of alcohol consumption and subsequent changes in blood pressure levels among non-hypertensive adults

Abstract Given the dynamic characteristic of an individual’s drinking behaviors, comprehensive consideration of alcohol consumption variation using repeated measures may improve insight into the nature of its association with blood pressure (BP) change. We examined the association between longitudinal alcohol consumption (trajectory and quantity) and changes in BP and pulse pressure (PP) among Korean aged ≥40 years living in rural areas. Totally, 1682 hypertension-free participants who completed all three health examinations (median, 5.3 years) were included. All three visits were used to determine the cumulative trajectory of and quantity of alcohol consumption and the latest two visits and the last visit were used for the recent trajectory and the most recent quantity of alcohol consumption, respectively. Changes in BP and PP from the baseline to the 3rd visit were used as outcome. In men, ≥30 ml/d cumulative average alcohol consumption was associated with the greatest increase in systolic BP (SBP) in both baseline outcome-unadjusted (2.9 mmHg, p-value = 0.032) and -adjusted models (3.6 mmHg, p-value = 0.001) and the given association for the most recent alcohol consumption was observed in the baseline outcome-adjusted model (3.9 mmHg, p-value = 0.003). For PP, similar associations were observed only in the baseline outcome-adjusted model. No meaningful associations in diastolic BP in men and any BP or PP in women existed. The quantity of alcohol consumption than the trajectory may be significantly related to raised SBP and a possible short-term influence of the most recent alcohol consumption may exist when baseline SBP adjusted in men.

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Negative Air Pressure on Wet Cupping in Decreasing Blood Pressures in Hypertensive Patients

Nurse Media Journal of Nursing ◽

10.14710/nmjn.v7i2.15177 ◽

2018 ◽

Vol 7 (2) ◽

pp. 116

Author(s):

Budi Darmawan ◽

Diyah Fatmasari ◽

Rr. Sri Endang Pujiast

Keyword(s):

Blood Pressure ◽

Repeated Measures ◽

Community Health Centers ◽

Intervention Group ◽

Air Pressure ◽

Control Group ◽

P Value ◽

Decrease Blood Pressure ◽

Blood Pressures ◽

The Mean

Background: Wet cupping, furthermore mentioned cupping, decreases blood pressures through the level of negative air pressures added by hydrostatics filtration pressure to reinforce the power of fluids filtration in capillaries. However, an appropriate negative air pressure to decrease blood pressure remains an uncertainty.Purpose: This study aimed to analyze negative air pressure differences on cupping in decreasing blood pressures in hypertensive patients.Methods: This is a quasi-experimental design conducted in three Community Health Centers in Langsa City, Aceh, Indonesia. The samples were 36 hypertensive males with age from 45 to 55, who were randomly stratified into two groups with cupping pressures 400 mbar (n=18) as the control group; and 540 mbar (n=18) as the intervention group. The cupping session was performed to each group on T1 (alkahil) point and in the middle line of both shoulders blade points. The systolic blood pressure (SBP) and diastolic blood pressures (DBP) were measured by validated automatic sphygmomanometer. The follow-up periods were one week and two weeks. The data were then analyzed by repeated measures ANOVA.Results: Cupping pressure of 400 mbar decreased the mean of SBP and DPB with a p-value of 0.450 and 0.026, respectively after two weeks of intervention. Meanwhile, cupping pressure of 540 mbar decreased the mean of SBP and DBP with a p-value of 0.006 and 0.057, respectively. Tests of within-subjects resulted in the p-value of 0.250 (SBP) and 0.176 (DBP) after two weeks of intervention. There were no significant differences in SBP and DBP between the intervention group and the control group.Conclusion: The cupping pressure between 400 mbar and 540 mbar could reduce blood pressure; however, the cupping pressure of 540 mbar yielded greater effect in decreasing blood pressure than the 400 mbar. Negative air vacuum pressure loads on cupping to decrease blood pressure should be considered between 400 to 540 mbar, and further studies are needed.

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Alcohol consumption and cardiorespiratory fitness in five population-based studies

European Journal of Preventive Cardiology ◽

10.1177/2047487317738594 ◽

2017 ◽

Vol 25 (2) ◽

pp. 164-172 ◽

Cited By ~ 9

Author(s):

Sebastian E Baumeister ◽

Jonas D Finger ◽

Sven Gläser ◽

Marcus Dörr ◽

Marcello RP Markus ◽

...

Keyword(s):

Alcohol Consumption ◽

Oxygen Uptake ◽

Cardiorespiratory Fitness ◽

Polynomial Regression ◽

Population Based ◽

Peak Oxygen Uptake ◽

Heavy Episodic Drinking ◽

P Value ◽

Independent Population ◽

Average Alcohol

Background Poor cardiorespiratory fitness is a risk factor for cardiovascular morbidity. Alcohol consumption contributes substantially to the burden of disease, but its association with cardiorespiratory fitness is not well described. We examined associations between average alcohol consumption, heavy episodic drinking and cardiorespiratory fitness. Design The design of this study was as a cross-sectional population-based random sample. Methods We analysed data from five independent population-based studies (Study of Health in Pomerania (2008–2012); German Health Interview and Examination Survey (2008–2011); US National Health and Nutrition Examination Survey (NHANES) 1999–2000; NHANES 2001–2002; NHANES 2003–2004) including 7358 men and women aged 20–85 years, free of lung disease or asthma. Cardiorespiratory fitness, quantified by peak oxygen uptake, was assessed using exercise testing. Information regarding average alcohol consumption (ethanol in grams per day (g/d)) and heavy episodic drinking (5+ or 6+ drinks/occasion) was obtained from self-reports. Fractional polynomial regression models were used to determine the best-fitting dose-response relationship. Results Average alcohol consumption displayed an inverted U-type relation with peak oxygen uptake ( p-value<0.0001), after adjustment for age, sex, education, smoking and physical activity. Compared to individuals consuming 10 g/d (moderate consumption), current abstainers and individuals consuming 50 and 60 g/d had significantly lower peak oxygen uptake values (ml/kg/min) (β coefficients = −1.90, β = −0.06, β = −0.31, respectively). Heavy episodic drinking was not associated with peak oxygen uptake. Conclusions Across multiple adult population-based samples, moderate drinkers displayed better fitness than current abstainers and individuals with higher average alcohol consumption.

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Prevalence and Associated Factors of Hypertension among Adults in Rural Uttarakhand: A Community Based Cross Sectional Study

Current Research in Nutrition and Food Science Journal ◽

10.12944/crnfsj.6.2.22 ◽

2018 ◽

Vol 6 (2) ◽

pp. 481-490

Author(s):

Vinita Thapliyal ◽

Karuna Singh ◽

Anil Joshi

Keyword(s):

Blood Pressure ◽

Waist Circumference ◽

High Blood Pressure ◽

Rural Areas ◽

Nutrition Transition ◽

Population Based ◽

P Value ◽

Sample Population ◽

Community Based ◽

Cross Sectional

India is in a state of transition epidemiological, economic, and demographic and nutrition transition. And all these transitions are leading to non communicable diseases like obesity, hypertension and insulin resistance. The study was aimed to estimate the Prevalence of hypertension and its associated risk factors among adults of rural Uttrakhand. It is a cross sectional community based study. Survey was conducted in rural areas of Uttrakhand, to make a sample size of 300 adults (18-45yr), using WHO STEPS questionnaire. Waist Circumference, Blood pressure, Body Mass Index of the participants was calculated. P value < 0.05 was considered significant. In the sample population based on systolic BP, 61.3% were non-hypertensive, 29.7% were pre-hypertensive and 9% were hypertensive. Based on diastolic BP, 43.3% were non-hypertensive, 32.7% were pre-hypertensive and 24% were hypertensive. Subjects with hypertension and pre-hypertension have higher BMI and waist circumference. A high prevalence rate of pre-hypertension and hypertension was depicted in rural areas of Uttrakhand region.4.8% of the female participants had systolic high blood pressure compared to the 11.9% of the male participants. On the other hand, 21.8% of the female participants had diastolic high blood pressure compared to the over 25% of the male participants.

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Oral nifedipine versus intravenous labetalol in hypertensive urgencies and emergencies of pregnancy: a randomized clinical trial

Obstetric Medicine ◽

10.1258/om.2012.120010 ◽

2012 ◽

Vol 5 (4) ◽

pp. 171-175 ◽

Cited By ~ 6

Author(s):

B Sathya Lakshmi ◽

Papa Dasari

Keyword(s):

Blood Pressure ◽

Repeated Measures ◽

Hypertensive Crisis ◽

P Value ◽

Chi Square ◽

Mixed Anova ◽

Arterial Blood ◽

Chi Square Test ◽

Time Required ◽

Group Effects

Background: Hypertensive crisis is an important cause of maternal and perinatal morbidity and mortality. Aim: To compare the efficacy of oral nifedipine and intravenous labetalol. Materials and methods: One hundred women with hypertensive crisis were randomized to receive either oral nifedipine 10 mg or intravenous labetalol 20 mg. Oral nifedipine was given 10 mg stat followed by 10 mg every 30 minutes up to a maximum of 50 mg. Intravenous labetalol was given 20 mg stat followed by 40 mg 30 minutes later then two more doses of 80 mg every 30 minutes up to a maximum of 220 mg. The primary outcome was the number of doses required to achieve target blood pressure (BP) and time required to reduce the mean arterial pressure by 25%. Secondary outcomes analysed included additional drugs required, resurgence of hypertensive crisis. Data were analysed using repeated measures analysis of variance (ANOVA), mixed ANOVA, unpaired t-test and chi square test and P value ≤0.05 was considered significant. Results: Systolic (SBP), diastolic (DBP) and mean arterial blood pressure (MAP) were lower than baseline at all time points of follow-up in both nifedipine and labetalol groups ( P < 0.01). P < 0.05 by repeated measures ANOVA for overall trend of changes in SBP, DBP and MAP for within-group effects in both nifedipine and labetalol groups and P < 0.05 by mixed ANOVA for between-group effects during entire observation period. The magnitude of fall in SBP, DBP and MAP was greater in the labetalol group compared with the nifedipine group ( P < 0.05). Target BP was achieved in 90% in the nifedipine group and 92% in the labetalol group. Maternal and fetal adverse effects were infrequent. Conclusion: Both oral nifedipine and intravenous labetalol are effective in the treatment of hypertensive crisis. Intravenous labetalol may have benefits because it is more effective in reducing the SBP, DBP and MAP to target levels with a lower number of doses.

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Is a single bout of exercise also a viable tool for blood pressure management in African and Asian populations? The HYPE2X trial protocol and design

European Journal of Preventive Cardiology ◽

10.1093/eurjpc/zwab061.150 ◽

2021 ◽

Vol 28 (Supplement_1) ◽

Author(s):

M Bersaoui ◽

SM Baldew ◽

J Toelsie ◽

R Buys ◽

VA Cornelissen

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Repeated Measures ◽

Vascular Function ◽

Blood Pressure Monitoring ◽

Handgrip Strength ◽

P Value ◽

Isometric Handgrip ◽

Asian Populations ◽

Response To Exercise

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Current national and international guidelines recommend exercise as the first line treatment (class IA recommendation) for hypertension. These guidelines are based on research performed in predominantly Caucasian populations, yet the potency of exercise for lowering blood pressure (BP) is less studied in non-Caucasian populations. It is well-known that a great variability exists in the response to pharmacological antihypertensive treatments among ethnic groups. However, it is not clear whether this variability is also present regarding the BP response to exercise. The ‘Hypertension, Ethnicity and Exercise’ (HYPE²X ) trial will i) investigate whether a short bout of isometric strength or endurance exercise lowers blood pressure in African and Asian populations; ii) evaluate and compare differences in acute response to exercise between the Africans and Asians, and iii) increase our understanding on mechanisms related to blood pressure responses to exercise in these non-Caucasian populations. Methods and analyses A randomized controlled crossover trial will be conducted in 60 adults of African (n = 30; 50% female) or Asian (n = 30, 50% female) origin, ≥ 18 years. Healthy individuals with high to normal blood pressure (SBP: 130 – 139 mmHg or and DBP: 85 – 89 mmHg) or grade I hypertension (grade 1, SBP: 140 – 159 mmHg or DBP: 90 – 99 mmHg) will be recruited at outpatient clinics in Suriname between November 2020 – February 2021. Patients will complete three experimental sessions in a randomized order: a 30 minute walking/running bout at 40-60% of heart rate reserve; an isometric handgrip session at 30% of maximal handgrip strength and a sitting control session. (See Figure 1). Measurements will be performed before and immediately after each session. The primary outcome is daytime blood pressure measured by means of 24h blood pressure monitoring. Secondary outcomes include office BP, autonomic function (heart rate variability), cardiac function (left ventricle function), vascular function (pulse wave velocity and flow-mediated dilation) and the renin-angiotensin aldosterone system (plasma renin and aldosterone levels). Analyses will be performed using mixed models for repeated measures. A two-tailed p-value <0.05 will be considered statistically significant. Conclusion It is anticipated that the HYPE²X trial will contribute to a better understanding of the response of non-Caucasians to lifestyle interventions, in particular exercise therapy. Abstract Figure 1. Flowchart of the RCOT

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Abstract P273: Longitudinal Association Between Body Weight Change and 6-year Change of Blood Pressure in Japanese Men

Circulation ◽

10.1161/circ.135.suppl_1.p273 ◽

2017 ◽

Vol 135 (suppl_1) ◽

Author(s):

Shin-ya Nagasawa

Keyword(s):

Blood Pressure ◽

Body Weight ◽

Repeated Measures ◽

Estimating Equation ◽

Repeated Measures Analysis ◽

Longitudinal Association ◽

Drinking Status ◽

Physical Examinations ◽

The Right ◽

Adjusted Model

Objective: Overweight is associated with increases in the risks of hypertension and cardiovascular disease. However, long-term and especially repeated measures analysis about relationship between body weight (BW) change and blood pressure (BP) change is only a little. We investigate the longitudinal relationship between BW change and years-long change of BP in a prospective cohort study. Participants: A total of 2546 male employees aged 25-53 years without use of antihypertensive drug in a metal products factory in Japan. Measurements: The BP was annually measured once in the right arm after 5 min of rest in a seated position, by well-trained nurses using a standard mercury sphygmomanometer from 2003 (baseline) to 2009. Physical examinations and information on lifestyle and use of medicine were annually measured or confirmed during the same period. The associations between difference of BW from 2003 to 2008 and 6-years change of systolic and diastolic BP from 2003 to 2009 were analyzed with generalized estimating equation models. Covariates in full adjusted model were age, body mass index, and smoking and drinking status in baseline. Results: Mean ± standard deviation (SD) of age, height, and BW in 2003 was 39.3 ± 8.0 years, 170.6 ± 6.0 cm, and 68.2 ± 9.9 kg, respectively. Mean ± SD of BW in 2008 was 68.8 ± 10.2 kg. Mean ± SD of systolic and diastolic BP in 2003 were 119.7 ± 14.6 and 74.3 ± 11.3 mmHg, respectively. Systolic and diastolic BP in 2009 were 120.5 ± 15.1 and 76.4 ± 10.9 mmHg, respectively. In full adjusted model, 1 kg increase of BW in 5 years was significantly associated with 0.17 mmHg higher systolic BP ( P = 0.024) and 0.113 mmHg diastolic BP ( P = 0.012) in 6 years. Conclusions: Beyond relevant covariates, increasing BW significantly elevated both systolic and diastolic BP.

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THE EFFECTIVENESS OF DIETS PROGRAM FOR PREECLAMPSIA ON BLOOD PRESSURE CONTROL AMONG PREGNANT WOMEN IN SOUTH TANGERANG

Nurse and Health: Jurnal Keperawatan ◽

10.36720/nhjk.v10i1.232 ◽

2021 ◽

Vol 10 (1) ◽

pp. 89-98

Author(s):

Aanisah Zahran ◽

Irma Nurbaeti

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Pregnant Women ◽

Diastolic Blood Pressure ◽

Repeated Measures ◽

Pressure Control ◽

P Value ◽

Measure Blood Pressure ◽

Eta Squared ◽

The Mean

Background: Preeclampsia is one of three causes of death for pregnant women, contributed to about 27% of maternal mortality in Indonesia. One of intervention that can be made for pregnant women to handling preeclampsia is diet for preeclampsia. Objectives: The purpose this study was to investigate the effectiveness of diets program for preeclampsia on decreasing blood pressure in pregnant women. Methods: A pre-experimental design with one group pretest – posttest was carried out. Population was all pregnant women who experience preeclampsia in Public Health Center in Ciputat South Tangerang. Twenty pregnant women who met criteria and completed the intervention were included in this study by using purposive sampling. Researcher explained the program diet and participants received program diets for preeclampsia in the form of a food list table, and fill in a table of food they consumed every day. Sphygmomanometer to measure blood pressure was used. Data collection with measure blood pressure was performed three times, before intervention, two weeks after diet program and one month after diet program. Repeated Measures ANOVA was applied to analysis with α = 0.05. Results: The mean scores of Systolic blood pressure was 147.06; 143.81; 140.38 in first, second and third collection, respectively. Systolic blood pressure in pregnant women with preeclampsia significantly decreased within two weeks after intervention (F = 31.30; p-value = 0.0001; Eta Squared= 0.676). The mean score of diastolic blood pressure was 102.31, 99.00 and 91.56 respectively. Diastolic blood pressure within two weeks after intervention decreased (F= 19.05; p-value= 0.0001; Eta Squared= 0.560). Conclusion: Diets Programs for Preeclampsia could decrease both systole and diastole blood pressure. The recommendation for pregnant women who have Preeclampsia is to manage preeclampsia diets regularly. Keywords: Blood pressure, diets program, preeclampsia, pregnant.

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Mobile-Friendly Dashboards to Display Associations Between Cited-by and Similar Journals on Mobile Health Research: A Bibliometric Study (Preprint)

10.2196/preprints.11771 ◽

2018 ◽

Author(s):

Tsair-Wei Chien ◽

Hsien-Yi Wang ◽

Yang Shao ◽

Willy Chou

Keyword(s):

Social Network ◽

Mobile Health ◽

Health Research ◽

Similarity Criteria ◽

Network Density ◽

Deep Insight ◽

Density Indices ◽

The Subject ◽

The Given ◽

Insight Into

BACKGROUND Researchers often spend a great deal of time and effort retrieving related journals for their studies and submissions. Authors often designate one article and then retrieve other articles that are related to the given one using PubMed’s service for finding cited-by or similar articles. However, to date, none present the association between cited-by and similar journals related to a given journal. Authors need one effective and efficient way to find related journals on the topic of mobile health research. OBJECTIVE This study aims (1) to show the related journals for a given journal by both cited-by and similarity criteria; (2) to present the association between cited-by and similarity journals related to a given journal; (3) to inspect the patterns of network density indices among clusters classified by social network analysis (SNA); (4) to investigate the feature of Kendall's coefficient(W) of concordance. METHODS We obtained 676 abstracts since 2013 from Medline based on the keywords of ("JMIR mHealth and uHealth"[Journal]) on June 30, 2018, and plotted the clusters of related journals on Google Maps by using MS Excel modules. The features of network density indices were examined. The Kendall coefficient (W) was used to assess the concordance of clusters across indices. RESULTS This study found that (1) the journals related to JMIR mHealth and uHealth are easily presented on dashboards; (2) a mild association(=0.14) exists between cited-by and similar journals related to JMIR mHealth and uHealth; (3) the median Impact Factor were 3.37 and 2.183 based on the representatives of top ten clusters grouped by the cited-by and similar journals, respectively; (4) all Kendall’s coefficients(i.e., 0.82, 0.89, 0.92, and 0.75) for the four sets of density centrality have a statistically significant concordance (p < 0.05). CONCLUSIONS SNA provides deep insight into the relationships of related journals to a given journal. The results of this research can provide readers with a knowledge and concept diagram to use with future submissions to a given journal in the subject category of Mobile Health Research. CLINICALTRIAL Not available

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Patterns of Alcohol Consumption in the PURE Poland Cohort Study and Their Relationship with Health Problems

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18084185 ◽

2021 ◽

Vol 18 (8) ◽

pp. 4185

Author(s):

Katarzyna Zatońska ◽

Piotr Psikus ◽

Alicja Basiak-Rasała ◽

Zuzanna Stępnicka ◽

Maria Wołyniec ◽

...

Keyword(s):

Cohort Study ◽

Alcohol Consumption ◽

Rural Areas ◽

Urban Areas ◽

Level Of Education ◽

Adult Participants ◽

Frequent Consumption ◽

Urban And Rural Areas ◽

Socio Demographic Factors ◽

High Level

(1) Background: Alcohol is a leading risk factor of premature morbidity and mortality. The objective of this study was to investigate the patterns of alcohol consumption in the PURE Poland cohort study baseline. (2) Methods: A Polish cohort was enrolled in the baseline study in 2007–2010. The study group consisted of 2021 adult participants of urban and rural areas from the Lower Silesia voivodeship in Poland (747 men and 1274 women). (3) Results: In the overall study population, 67.3% were current drinkers, 10.3% were former drinkers, and 22.4% were abstainers. Current use of alcohol products was more prevalent in men (77.2%), people living in urban areas (73.0%), and people with a higher level of education (78.0%). The percentage of current drinkers decreased with increasing age (from 73.4% in 30- to 44-year-olds to 48.8% in participants aged 64 and more). The majority of participants (89.2%) declared a low level of alcohol intake. The chance of high level of intake of alcohol was four times higher in men than in women (OR 4.17; CI 1.64–10.6). The majority of participants (54.6%) declared most frequent consumption of low-alcohol drinks (beer, wine) and 21% declared most frequent consumption of spirits. Current drinkers had almost 1.5-fold higher odds of diabetes and cardiovascular diseases (CVD) than never drinkers (OR 1.49, CI 1.03–2.17; OR 1.66, CI 1.27–2.18, respectively). Former drinkers had higher odds for hypertension and CVD than never drinkers (1.73, CI 1.05–2.85; OR 1.76, CI 1.22–2.53, respectively). (4) Conclusions: In our cohort study, we observed several socio-demographic factors differentiating the patterns of alcohol consumption. The preventive programs should focus predominantly on men, people aged <45 years, and those with a higher level of education.

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Using syndromic measures of mortality to capture the dynamics of COVID-19 in Java, Indonesia, in the context of vaccination rollout

BMC Medicine ◽

10.1186/s12916-021-02016-2 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Bimandra A. Djaafara ◽

Charles Whittaker ◽

Oliver J. Watson ◽

Robert Verity ◽

Nicholas F. Brazeau ◽

...

Keyword(s):

Rural Areas ◽

Vaccination Campaign ◽

Control Measures ◽

Additional Insight ◽

Short Term ◽

If Current ◽

Vaccine Impact ◽

Potential Impact ◽

The Impact ◽

Insight Into

Abstract Background As in many countries, quantifying COVID-19 spread in Indonesia remains challenging due to testing limitations. In Java, non-pharmaceutical interventions (NPIs) were implemented throughout 2020. However, as a vaccination campaign launches, cases and deaths are rising across the island. Methods We used modelling to explore the extent to which data on burials in Jakarta using strict COVID-19 protocols (C19P) provide additional insight into the transmissibility of the disease, epidemic trajectory, and the impact of NPIs. We assess how implementation of NPIs in early 2021 will shape the epidemic during the period of likely vaccine rollout. Results C19P burial data in Jakarta suggest a death toll approximately 3.3 times higher than reported. Transmission estimates using these data suggest earlier, larger, and more sustained impact of NPIs. Measures to reduce sub-national spread, particularly during Ramadan, substantially mitigated spread to more vulnerable rural areas. Given current trajectory, daily cases and deaths are likely to increase in most regions as the vaccine is rolled out. Transmission may peak in early 2021 in Jakarta if current levels of control are maintained. However, relaxation of control measures is likely to lead to a subsequent resurgence in the absence of an effective vaccination campaign. Conclusions Syndromic measures of mortality provide a more complete picture of COVID-19 severity upon which to base decision-making. The high potential impact of the vaccine in Java is attributable to reductions in transmission to date and dependent on these being maintained. Increases in control in the relatively short-term will likely yield large, synergistic increases in vaccine impact.

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