scholarly journals Study on the Epidemiology of Typhoid Fever

1927 ◽  
Vol 27 (1) ◽  
pp. 14-31 ◽  
Author(s):  
I. J. Kligler

A study was made of the available statistical data bearing on the epidemiology of typhoid in Palestine. It apears from this analysis that:1. The typhiod epidemicity is not due to a single source such as contaminated water or food. The seasonal prevalence of the disease corresponds with the normal seasonal incidence of typhiod, and is, therefore, in the nature of a contact infection.2. There is no striking difference in age, sex or race susceptibility. In Tel Aviv the age group 5–14 shows a lower incidence than the corresponding age group in Jerusalem or the higher age group 15–29 in Jerusalem and Tel Aviv. There is, however, no difference in susceptibility between the age group 15–29 in Jerusalem and that in Tel Aviv.3. From a graphic comparisos, the calculation of the coefficient of correlation of the limited experience (six years), and a comparison of the prevalence of the disease in the immigrant and indigenous population, there appears to be a significant correlation between the net population increment and epidemicity. These results, if confirmed by a longer experience, are in accord with those obtained in the remarkable mice experiments conducted by the English and American investigators.4. Although, at the beginning, the morbidity and mortality is higher in the immigrant group, there is an evident tendency at equalisation, and in the second year the incidence in the indigenous population is the same as that among the immigrants.5. The above results indicate the path of control: (a) every immigrant, particularly those between the ages 5–29, should be properly vaccinated against typhoid. By raising the resistance of the new population, the possibility of epidemics among them, and consequently later among the resident population, will be averted; (b) the reduction of endemic typhoid can be brought about by reducing the dosage of the infectious microbes. This can only be brought about by concentration of effort on the early detection and isolation of cases and the vaccination of all contacts. These two measures would seem to offer a prompt and relatively simple solution to the typhoid problem in Palestine.

2021 ◽  
pp. 004947552110174
Author(s):  
Karen Melissa Ordoñez Díaz ◽  
Juan José Gutiérrez Paternina

Invasive infections due to Neisseria meningitidis in Colombia are unusual in newborns, in contrast to infections due to Plasmodium vivax which is one of the main pathogens related to the presentation of fever in this age group, especially in the indigenous population. We report a case of co-infection of these two microorganisms in a child.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xinjun Li ◽  
Kristina Sundquist ◽  
Jan Sundquist ◽  
Asta Försti ◽  
Kari Hemminki

AbstractChildhood acute lymphoblastic leukemia (ALL) has an origin in the fetal period which may distinguish it from ALL diagnosed later in life. We wanted to test whether familial risks differ in ALL diagnosed in the very early childhood from ALL diagnosed later. The Swedish nation-wide family-cancer data were used until year 2016 to calculate standardized incidence ratios (SIRs) for familial risks in ALL in three diagnostic age-groups: 0–4, 5–34 and 35 + years. Among 1335 ALL patients diagnosed before age 5, familial risks were increased for esophageal (4.78), breast (1.42), prostate (1.40) and connective tissue (2.97) cancers and leukemia (2.51, ALL 7.81). In age-group 5–34 years, rectal (1.73) and endometrial (2.40) cancer, myeloma (2.25) and leukemia (2.00, ALL 4.60) reached statistical significance. In the oldest age-group, the only association was with Hodgkin lymphoma (3.42). Diagnostic ages of family members of ALL patients were significantly lower compared to these cancers in the population for breast, prostate and rectal cancers. The patterns of increased familial cancers suggest that BRCA2 mutations could contribute to associations of ALL with breast and prostate cancers, and mismatch gene PMS2 mutations with rectal and endometrial cancers. Future DNA sequencing data will be a test for these familial predictions.


PEDIATRICS ◽  
1966 ◽  
Vol 37 (2) ◽  
pp. 392-392
Author(s):  
THOMAS E. CONE

This is a timely, concise, eminently practical, thoughtfully, even tenderly, written 28 page report of a recent WHO Expert Committee meeting on the health problems of adolescence. The members and the consultants to the Committee deftly summarize the major worldwide trends affecting our adolescent population. The size of this population is staggering; in the age group 15-19 years alone there are already 300 million adolescents in the world, and there seems every likelihood that these numbers will increase rapidly during the next decade.


2019 ◽  
Vol 147 (11-12) ◽  
pp. 683-687
Author(s):  
Marija Mladenovic ◽  
Nedeljko Radlovic ◽  
Zoran Lekovic ◽  
Biljana Vuletic ◽  
Vladimir Radlovic ◽  
...  

Introduction/Objective. The classic type of celiac disease (CD) is most common in children under two years of age. The aim of this study was to investigate whether breastfeeding, particularly breastfeeding during gluten introduction, and timing of gluten introduction, influence the onset of CD at this age. Methods. We retrospectively analyzed medical records of 93 children, 40 in the first and 53 in the second year, with a classic CD diagnosed at the University Children?s Hospital, Belgrade between 2000 and 2010. The diagnosis of CD was based on the criteria of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) from 1989. Results. Duration of breastfeeding reduced the onset of the CD in the first year p = 0.039 (OR = 1.43 95% CI 1.019?1.899). Also, breastfeeding at the time of gluten introduction significantly delayed the age at diagnosis (F = 1.671, t = 2.39, p = 0.029). The timing of gluten introduction did not affect the age of occurrence of CD in these group of children. Conclusion. Longer breastfeeding, and breastfeeding at the time of gluten introduction, postponed the onset of classic CD in patients up to two years. The association between the occurrence of CD and the time of introduction of gluten in this age group of patients has not been established.


2020 ◽  
Vol 3 (2) ◽  
pp. 43-45
Author(s):  
Sridhara Reddy ◽  
Gurunadh Satyanarayana Velamakanni ◽  
Shailesh Mogra

ABSTRACT Aim To estimate the prevalence of ocular morbidity among primary school children in Delhi area. Materials and methods This was a descriptive cross-sectional study. The study was conducted among primary school children of age group 5–12 years in Delhi area. A total of 1,100 school-going children were evaluated. After questionnaire administration, visual acuity, examination of anterior and posterior segment structures of the eyes of the children were carried out. For the statistical analysis, children were divided into three groups: group I (5–7 years), group II (8–10 years), and group III ((<12 years) based on age. Results A total of 1,100 school children (625 boys and 475 girls) participated in the study. A total of 282 (25.6%) children had visual impairment and 315 (28.6%) children had ocular morbidities. The common ocular morbidities identified were refractive error 25.6%, color vision defective 0.9%, convergence defect 1.8%, and squint 0.2%. The older age group (8–10 years) had a higher prevalence of refractive error, especially myopia, compared to the younger age group (5–7 years) and group ((<12 years) (p < 0.001). Conclusion A high prevalence of ocular morbidity among school children of age group 8–10 years was observed. Refractive errors were the most common ocular disorders. This study emphasized that a simple school visual screening program is effective for the early detection of ocular problems. How to cite this article Reddy S, Velamakanni GS, Mogra S. Prevalence Study of Ocular Morbidity among Primary School Children in Delhi Area. J Med Acad 2020;3(2):43–45.


2021 ◽  
pp. 83-88
Author(s):  
Natalia SIUDZIŃSKA

The complexity of word-formation in Slavic languages, especially in the Polish language, makes it very difficult for Polish speaking children and bilingual children to learn, especially when the second language is not Slavic. In this article I would like to concentrate on the linguistic problems in the context of learning word-formation by bilingual children aged 5-9 who live in Ireland and who learn Polish and English at the same time. I would like to juxtapose their level of word formation competence with those children who are Polish language speakers living in Poland and who are in the same age group (5-9). The research described below concerns the category of feminine gender words. The linguistic data used for the description were collected during the fieldwork research carried out with the group of thirty bilingual children. The results of the research allowed to establish the differences in the linguistic development of monolingual and bilingual children and to indicate the factors that determine the acquisition of word-formation competences. This type of research will help teachers and other specialists (psychologists, speech therapists) working with such children to better assess the language skills of bilingual children. They also allow to estimate the scale of difficulties that Polish children returning from emigration will encounter.


RELC Journal ◽  
2016 ◽  
Vol 47 (3) ◽  
pp. 349-362 ◽  
Author(s):  
Anna C-S Chang ◽  
Sonia Millett

This study investigates the effects on developing L2 listening fluency through doing extended listening-focused activities after reading and listening to audio graded readers. Seventy-six EFL university students read and listened to a total of 15 graded readers in a 15-week extensive listening programme. They were divided into three groups (Group 5, n = 30; Group 10, n = 20; Group 15, n =26) according to the number of post-listening-focused activities they completed. Another group who did not receive extensive listening served as the control group (Group 0, n =39). All participants were given a pre-test containing teacher-developed tests and a full-length simulated Test of English for International Communication (TOEIC) listening test. Similar tests were repeated at the end of the programme. The study addresses the effect size of improvement that students made from listening to audio graded readers and doing post-listening-focused activities, the degree to which students progressed on their TOEIC listening test, and the transferring effect from narrative-type input to conversational-type listening. Results show that the effect size was very small, medium, and very large on the listening improvement for Group 5, Group 10 and Group 15 respectively. On their post-TOEIC tests, Groups 5, 10 and 15 made approximately 2, 9 and 16 points out of 100 respectively. Finally, only Group 15 demonstrated some transfer effect from narrative to conversational input type of listening. This study also discussed the reasons low-level learners need to read many more texts to see more significant improvement.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Vivek Verma ◽  
Ashwani Kumar Mishra ◽  
Anju Dhawan ◽  
Dilip C. Nath

Abstract Background Shannon’s index is one of the measures of biodiversity, which is intended to quantify both richness and evenness of the species/individuals in the ecosystem or community. However, application of Shannon’s index in the field of substance use among the street children has not been done till date. Methods This paper is concerned with methods of estimating Shannon’s diversity index (SDI), which can be used to capture the variation in the population due to certain characteristics. Under the consideration that the probability of abundance, based on certain characteristics in the population, is a random phenomenon, we derive a Bayesian estimate in connection with Shannon’s information measure and their properties (mean and variance), by using a probability matching prior, through simulation and compared it with those of the classical estimates of Shannon. The theoretical framework has been applied to the primary survey data of substance use among the street children in Delhi, collected during 2015. The measure of diversity was estimated across different age profiles and districts. Results The results unrevealing the diversity estimate for street children corresponding to each region of Delhi, under both the classical and Bayesian paradigms. Although the estimates were close to one another, a striking difference was noted in the age profile of children. Conclusions The Bayesian methodology provided evidence for a greater likelihood of finding substance-using street children, belonging to the lower age group (7-10, maximum Bayesian entropy-3.73), followed by the middle (11-14) and upper age group (15-18). Moreover, the estimated variance under the Bayesian paradigm was lesser than that of the classical estimate. There is ample scope for further refinement in these estimates, by considering more covariates that may have a possible role in initiating substance use among street children in developing countries like India.


2004 ◽  
Vol 50 (1) ◽  
pp. 57-61 ◽  
Author(s):  
M. Divizia ◽  
R. Gabrieli ◽  
D. Donia ◽  
A. Macaluso ◽  
A. Bosch ◽  
...  

Three different studies are reported concerning the environmental pollution caused by viruses in Albania. The first study describes an outbreak of gastroenteritis in the capital city, involving 2,722 children attending the Paediatric Unit of Tirana Hospital. The age group with the highest morbidity was 0-5 years, with 89.5%; no fatalities were recorded during the outbreak. Rotavirus was detected in 26/28 faecal samples by RT-PCR, although astrovirus, adenovirus and calicivirus were also present. The second study describes an outbreak of hepatitis A virus involving the city of Lac. Two hundred cases were recorded, with the highest incidence in the age-group 5-9 years. Phylogenetic analysis of the VP1/2A region showed the presence of a unique sequence: genotype IA. Rotavirus was identified in drinking-water samples collected during the outbreak. The third study describes the prevalence of HAV and HEV in 202 sera randomly collected from 12 different cities in Albania. HAV showed a high incidence (66.2%), whereas none was positive for HEV. The genomic analysis of the VP1/2A junction revealed the presence of only one genotype (IA) with few point mutations and just two amino acid substitutions at codons 22 and 34. Additionally, two potential antigenic variants were detected, the first at position 46 of VP3 and the second at position 23 of VP1.


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