scholarly journals A one-year survey of nosocomial bacteraemia at a Danish university hospital

1986 ◽  
Vol 97 (3) ◽  
pp. 471-478 ◽  
Author(s):  
K. Eliasen ◽  
P. B. Nielsen ◽  
F. Espersen
Keyword(s):  
Staphylococcus Epidermidis ◽  
Foreign Bodies ◽  
University Hospital ◽  
Focus Of Infection ◽  
One Year ◽  
Tract Infections ◽  
Catheter Infections ◽  
Hospital Acquired ◽  
Intravenous Catheters ◽  
Overall Mortality

SUMMARYA 1-year prospective study of nosocomial bacteraemia was performed at Hvidovre Hospital with special reference to frequency, focus of infection and prognosis. All patients were examined clinically in order to confirm the bacteraemia. In total, 98 hospital-acquired bacteraemias were observed, giving an incidence rate of 0·28%. Bacteraemia due to Escherichia coli, Staphylococcus aureus and Staphylococcus epidermidis predominated. The overall mortality was 38%; 65% of the patients with S. aureus bacteraemia died, 25% due to the bacteraemia. The most common types of infection were urinary tract infections and intravenous catheter infections. Fifty-five of the bacteraemias were caused by foreign bodies, mostly urinary catheters and intravenous catheters, and in 14 cases the focus was unknown. The patient population was severely ill patients. We conclude that nosocomial bacteraemia occurs specially in severely ill patients often preceded by indwelling urinary or intravenous catheters. The patients seldom die due to the bacteraemia, but they die with concomitant bacteraemia.

HOSPITAL INFECTION IN SURGICAL DEPARTMENTS AT HUE UNIVERSITY HOSPITAL IN 2015

2016 ◽  
pp. 39-43
Author(s):  
Dinh Binh Tran ◽  
Dinh Tan Tran
Keyword(s):  
Surgical Site Infection ◽  
Surgical Intervention ◽  
University Hospital ◽  
Hospital Infections ◽  
Site Infection ◽  
Cross Sectional ◽  
Surgical Interventions ◽  
Hospital Acquired Infections ◽  
Tract Infections ◽  
Hospital Acquired

Objective: To study nosocomial infections and identify the main agents causing hospital infections at Hue University Hospital. Subjects and Methods: A cross-sectional descriptive study of 385 patients with surgical interventions. Results: The prevalence of hospital infections was 5.2%, surgical site infection was the most common (60%), followed by skin and soft tissue infections (35%), urinary tract infections (5%). Surgical site infection (11.6%) in dirty surgery. There were 3 bacterial pathogens isolated, including Staphylococcus aureus (50%), Pseudomonas aeruginosa and Enterococcusspp (25%). Conclusion: Surgical site infection was high in hospital-acquired infections. Key words: hospital infections, surgical intervention, surgical site infection, bacteria

scholarly journals Sepsis in a university hospital: a prospective study for the cost analysis of patients' hospitalization

2016 ◽  
Vol 50 (2) ◽  
pp. 302-308 ◽  
Author(s):  
Maynara Fernanda Carvalho Barreto ◽  
Mara Solange Gomes Dellaroza ◽  
Gilselena Kerbauy ◽  
Cintia Magalhães Carvalho Grion
Keyword(s):  
Severe Sepsis ◽  
Public Hospital ◽  
Epidemiological Data ◽  
University Hospital ◽  
Preventive Actions ◽  
Focus Of Infection ◽  
One Year ◽  
A Prospective Study ◽  
The Cost ◽  
Pulmonary Focus

Abstract OBJECTIVE To estimate the cost of hospitalization of patients with severe sepsis or septic shock admitted or diagnosed in the Urgent and Emergency sector at a university hospital and followed until the clinical outcome. METHOD An epidemiological, prospective, observational study conducted in a public hospital in southern Brazil for the period of one year (August 2013 to August 2014). Sepsis notification forms, medical records and data of the cost sector were used for the collection of clinical and epidemiological data. RESULTS The sample comprised 95 patients, resulting in a total high cost of hospitalization (R$ 3,692,421.00), and an average of R$ 38,867.60 per patient. Over half of the total value of the treatment of sepsis (R$ 2,215,773.50) was assigned to patients who progressed to death (59.0%). The higher costs were related to discharge, diagnosis of severe sepsis, the pulmonary focus of infection and the age group of up to 59 years. CONCLUSION The high cost of the treatment of sepsis justifies investments in training actions and institution of protocols that can direct preventive actions, and optimize diagnosis and treatment in infected and septic patients.

scholarly journals An evaluation of six-year Stenotrophomonas maltophilia infections in a university hospital

2020 ◽  
Vol 20 (3) ◽  
pp. 1118-1123
Author(s):  
Nevin Ince ◽  
Dilek Yekenkurul ◽  
Ayşe Danış ◽  
Emel Çalışkan ◽  
İdris Akkaş
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Stenotrophomonas Maltophilia ◽  
Bloodstream Infections ◽  
University Hospital ◽  
Invasive Procedures ◽  
Tract Infections ◽  
Rational Use Of Antibiotics ◽  
Resistance Rates ◽  
Hospital Acquired

Background: Stenotrophomonas maltophilia is a Gram-negative bacillus and opportunistic emergent pathogen causing hospi- tal-acquired infections (HAIs). Due to risk factors such as prolonged intensive care unit stay and invasive procedures, it has become one of the leading causes of HAIs. Objective: The aim of this study was to evaluate the epidemiology of S.maltophilia infections over a six-year period at Düzce University Hospital, Turkey. Methods: The incidence, clinical characteristics, antimicrobial susceptibility and outcomes of nosocomial S. maltophilia in- fections during this period were retrospectively analyzed. Results: During the study period, 67 samples obtained from 61 patients were identified. Pneumonias (82%) were the most common HAIs, followed by bloodstream infections (10.5%), urinary tract infections (3%), skin and soft tissue infections (3%) and surgical site infection (1.5%). Admission to intensive care, hospitalization exceeding 30 days, and previous use of broad-spectrum antibiotics constituted risk factors. Resistance to cotrimoxazole (6%) was lower than that to levofloxacin (18%). Conclusion: The most important risk factors for S.maltophilia infection in patients are previous exposure to antibiotics, pro- longed hospitalization and invasive procedures such as mechanic ventilation. Discharging patients as early as possible with the rational use of antibiotics may be effective in reducing S. maltophilia infections and resistance rates. Keywords: Stenotrophomonas maltophilia; hospital-acquired infections; epidemiology; risk factors.

scholarly journals Epidemiology, clinical relevance and prognosis of staphylococci in hospital-acquired postoperative intra-abdominal infections: an observational study in intensive care unit

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kévin Boussion ◽  
Nathalie Zappella ◽  
Nathalie Grall ◽  
Lara Ribeiro-Parenti ◽  
Grégory Papin ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clinical Outcomes ◽  
Clinical Characteristics ◽  
Tertiary Care ◽  
University Hospital ◽  
Coagulase Negative Staphylococci ◽  
One Year ◽  
Abdominal Infections ◽  
Hospital Acquired

AbstractThe pathogenic role of staphylococci in hospital-acquired postoperative intra-abdominal infections (HAIs) has never been evaluated. In a tertiary care university hospital, we assessed the clinical characteristics and outcomes of patients admitted to the intensive care unit for HAIs according to the presence of staphylococci (S-HAI) or their absence (nS-HAI) in peritoneal cultures. Patients with S-HAIs were compared to nS-HAIs patients. Overall, 380 patients were analyzed, including 87 (23%) S-HAI patients [29 Staphylococcus aureus (Sa-HAIs) and 58 coagulase-negative staphylococci (CoNS-HAIs)]. The clinical characteristics did not differ between the S-HAI and nS-HAI patients. Adequacy of empirical anti-infective therapy was achieved less frequently in the staphylococci group (54 vs 72%, respectively, p < 0.01). The 90-day (primary endpoint) and one-year mortality rates did not differ between these groups. The S-HAI patients had decreased rates of postoperative complication (p < 0.05). The adjusted analysis of the clinical outcomes reported a decreased frequency of surgical complications in the staphylococci group (OR 0.43, 95% CI [0.20–0.93], p = 0.03). While the trends toward decreased morbidity criteria were observed in S-HAI patients, the clinical outcomes were not different between the CoNS-HAI and Sa-HAI patients. In summary, our data are not substantial enough to conclude that staphylococci exhibit no pathogenicity in HAIs.

scholarly journals Identification and medical importance of coagulase-negative staphylococci species

1999 ◽  
Vol 117 (4) ◽  
pp. 175-178 ◽  
Author(s):  
Elaine Cristina Manini Minto ◽  
Cristiane Barelli ◽  
Roberto Martinez ◽  
Ana Lúcia da Costa Darini
Keyword(s):  
Staphylococcus Epidermidis ◽  
Antimicrobial Agents ◽  
University Hospital ◽  
Intravenous Catheter ◽  
Catheter Colonization ◽  
Coagulase Negative Staphylococci ◽  
Blood Samples ◽  
Medical Importance ◽  
The University ◽  
Intravenous Catheters

A total of 126 coagulase-negative staphylococci strains (CNS) were isolated from blood samples and from the intravenous catheters and cerebrospinal fluid of 103 patients admitted to the University Hospital of Ribeirão Preto. Staphylococcus epidermidis (68.2%), S. haemolyticus (11.1%) and S. hominis (3.2%) were the most frequent species. The last two CNS showed greater resistance to antimicrobial agents than S. epidermidis. CNS were the agents of infection in 10.7% of the patients and the agents of intravenous catheter colonization in 18.4% of the cases.

scholarly journals Respiracinio sincitinio viruso infekcijos aktualumas vaikų kardiochirurgijoje

2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Solveiga Umbrasaitė ◽  
Kęstutis Versockas
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Respiratory Syncytial Virus ◽  
Congenital Heart ◽  
Severe Form ◽  
University Hospital ◽  
Rsv Infection ◽  
Syncytial Virus ◽  
One Year ◽  
Tract Infections

Solveiga Umbrasaitė, Kęstutis VersockasVilniaus universiteto ligoninės Santariškių klinikos, Santariškių g. 2, LT-08661 VilniusEl paštas: [email protected] Įvadas / tikslas Respiracinis sincitinis virusas (RSV) yra dažniausia apatinių kvėpavimo takų infekcijos priežastis, ypač naujagimiams ir kūdikiams. Tarp vaikų, kuriems yra padidėjusi sunkios RSV infekcijos formos rizika, yra turinčių įgimtą širdies ydą. Ši rizika yra dar didesnė atliekant širdies operacijas. Šio tyrimo tikslas buvo išsiaiškinti, kiek yra infekuotų RSV vaikų tarp patenkančių į stacionarą operaciniam gydymui. Metodai ir rezultatai Specifiniai RSV imunoglobulinų testai buvo atlikti 32 vaikų grupėje (iš kurių 9 naujagimiai ir 23 kūdikiai). Teigiamų IgG antikūnų rasta 12 atvejų (41%), teigiamų IgM antikūnų – vienu. Išvados RSV infekuotų vaikų yra gana daug; dėl to tikslinga tęsti tyrimus. Kitas žingsnis būtų išsiaiškinti RSV infekcijos įtaką perioperacinei pacientų būklei ir pasyvios imunoprofilaktikos palivizumabu tikslingumą. Pagrindiniai žodžiai: respiracinis sincitinis virusas, įgimtos širdies ydos, imunoprofilaktika Relevance of RSV infection in children’s cardiac surgery Solveiga Umbrasaitė, Kęstutis VersockasVilnius University Hospital „Santariškių klinikos“, Santariškių str. 2, LT-08661 Vilnius, LithuaniaE-mail: [email protected] Background / objective Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections, especially in newborns and children under one year of age. Among children at a higher risk of a severe form of RSV infection are children with congenital heart disease. This risk is higher in case of heart operation.The purpose of this research was to reveal the incidence of RSV-infected patients among those admitted for surgical treatment. Methods and results Specific RSV immunoglobulin tests were performed for a group of 32 children (9 newborns and 23 infants). Positive IgG antibodies were found in 12 cases (41%) and positive IgM antibodies in one case. Conclusions The incidence of RSV-infected children is quite high; therefore, it is purposeful to continue research. The next step would be to reveal the influence of RSV infection on the perioperative condition of patients and the expediency of passive imunoprophylaxis with palivizumab. Key words: respiratory syncytial virus, congenital heart disease, imunoprophylaxis

Surveillance for Hospital-Acquired Infections on Surgical Wards in a Dutch University Hospital

2003 ◽  
Vol 24 (8) ◽  
pp. 584-590 ◽  
Author(s):  
Titia E. M. Kamp-Hopmans ◽  
Hetty E. M. Blok ◽  
Annet Troelstra ◽  
Ada C. M. Gigengack-Baars ◽  
Annemarie J. L. Weersink ◽  
...  
Keyword(s):  
Medical Center ◽  
University Hospital ◽  
Incidence Density ◽  
Gynecologic Surgery ◽  
Prospective Surveillance ◽  
Oncologic Surgery ◽  
Prevalence Survey ◽  
Hospital Acquired Infections ◽  
Tract Infections ◽  
Hospital Acquired

AbstractObjectives:To determine incidence rates of hospital-acquired infections and to develop preventive measures to reduce the risk of hospital-acquired infections.Methods:Prospective surveillance for hospital-acquired infections was performed during a 5-year period in the wards housing general and vascular, thoracic, orthopedic, and general gynecologic and gynecologic-oncologic surgery of the University Medical Center Utrecht, the Netherlands. Data were collected from patients with and without infections, using criteria of the Centers for Disease Control and Prevention.Results:The infection control team recorded 648 hospital-acquired infections affecting 550 (14%) of 3,845 patients. The incidence density was 17.8 per 1,000 patient-days. Patients with hospital-acquired infections were hospitalized for 19.8 days versus 7.7 days for patients without hospital-acquired infections.Prolongation of stay among patients with hospital-acquired infections may have resulted in 664 fewer admissions due to unavailable beds. Different specialties were associated with different infection rates at different sites, requiring a tailor-made approach. Interventions were recommended for respiratory tract infections in the thoracic surgery ward and for surgical-site infections in the orthopedic and gynecologic surgery wards.Conclusions:Surveillance in four surgical wards showed that each had its own prominent infection, risk factors, and indications for specific recommendations. Because prospective surveillance requires extensive resources, we considered a modified approach based on a half-yearly point-prevalence survey of hospital-acquired infections in all wards of our hospital. Such surveillance can be extended with procedure-specific prospective surveillance when indicated.

One-year all-cause mortality for 338 patients admitted with epistaxis in a large tertiary ENT centre

2019 ◽  
Vol 133 (06) ◽  
pp. 487-493 ◽  
Author(s):  
M J Corr ◽  
T Tikka ◽  
C M Douglas ◽  
J Marshall
Keyword(s):  
Risk Factors ◽  
Rating Scale ◽  
Performance Status ◽  
University Hospital ◽  
Retrospective Case ◽  
Large Teaching Hospital ◽  
All Cause Mortality ◽  
One Year ◽  
The One ◽  
Overall Mortality

AbstractObjectiveEpistaxis is the most common ENT emergency. This study aimed to assess one-year mortality rates in patients admitted to a large teaching hospital.MethodThis study was a retrospective case note analysis of all patients admitted to the Queen Elizabeth University Hospital in Glasgow with epistaxis over a 12-month period.ResultsThe one-year overall mortality for a patient admitted with epistaxis was 9.8 per cent. The patients who died were older (mean age 77.2 vs 68.8 years; p = 0.002), had a higher Cumulative Illness Rating Scale-Geriatric score (9.9 vs 6.7; p &lt; 0.001) and had a higher performance status score (2 or higher vs less than 2; p &lt; 0.001). Other risk factors were a low admission haemoglobin level (less than 128 g/dl vs 128 g/dl or higher; p = 0.025), abnormal coagulation (p = 0.004), low albumin (less than 36 g/l vs more than 36 g/l; p &lt; 0.001) and longer length of stay (p = 0.046).ConclusionThere are a number of risk factors associated with increased mortality after admission with epistaxis. This information could help with risk stratification of patients at admission and enable the appropriate patient support to be arranged.

scholarly journals Infectious morbidity and mortality in the infectious diseases department of the CHU Yalgado Ouédraogo in Burkina Faso in 2019

2021 ◽  
Vol 7 (1) ◽  
pp. 097-100
Author(s):  
Mamoudou Savadogo ◽  
Ismaël Diallo ◽  
K Apoline Sondo
Keyword(s):  
Infectious Diseases ◽  
Hiv Infection ◽  
Public Health Problem ◽  
University Hospital ◽  
Major Public Health Problem ◽  
Pulmonary Infections ◽  
Cross Sectional ◽  
Duration Of Hospitalization ◽  
One Year ◽  
Tract Infections

Introduction: Infectious diseases remain a major public health problem in developing countries. The objective of this study was to determine the epidemiological and clinical profile of infectious pathology in the infectious diseases department of CHU Yalgado Ouédraogo in Ouagadougou. Patients and method: This was a cross-sectional and retrospective study that took place in the infectious diseases department of the Yalgado Ouédraogo University Hospital from January 1, 2019 to December 31, 2019. Were included all patients hospitalized in the said service during the study period. For each patient retained sociodemographic, clinical and diagnostic data were collected. Results: In one year, 159 patients had been hospitalized in the infectious diseases department of the YO UHC. The mean age of the patients was 42±9 years with extremes of 15 and 80 years. The female sex was the most represented (55.5%) with a sex ratio of 0.8. The majority of patients (64%) came from the province of Kadiogo. The most frequently diagnosed infectious diseases were HIV infection (24%), pulmonary infections (21.8%), malaria (14%), dengue fever (9%), urinary tract infections (7.5%), meningitis (3.8%), typhoid fever (3%), rabies (3%), chicken pox (3%), tetanus (3.8%), toxoplasmosis (3.8%), and cutaneous leishmaniosis (3%). The signs of severity presented by our patients were dominated by dyspnea, severe anemia, and severe dehydration. The delay of consultation was 13.5 days and the average duration of hospitalization was 9.8 days, with a hospital mortality of 24%. Conclusion: HIV infection, malaria and pulmonary infections were the most frequent reasons for hospitalization. It is therefore important to strengthen the technical facilities of hospitals for early diagnosis and appropriate management of infectious pathology

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