The effectiveness of physical exercise interventions in the management of neuropsychiatric symptoms in dementia patients: a systematic review

2021 ◽  
pp. 1-14
Author(s):  
Komanthi Kouloutbani ◽  
Fotini Venetsanou ◽  
Alexandra Markati ◽  
Konstantinos E. Karteroliotis ◽  
Antonios Politis

ABSTRACT Background: The management of neuropsychiatric symptoms (NPS) in patients with dementia is a major challenge. Since no effective therapy has been found to date and drug treatments are associatedwith significant side effects, there seems to be a pressing need for alternative non-pharmacological interventions. Objectives: The current study aims to investigate and compare the effect of different types of physical exercise on the NPS. Methods: A systematic review of the literature was conducted according to the PRISMA guidelines. Five databases (SCOPUS, PubMed, SPORT Discus, Web of science and ScienceDirect) were searched using the appropriate algorithm. What was sought out was randomized control trials (RCTs) that applied physical activity interventions with specific characteristics (type, frequency, intensity, and duration) in patients with dementia or mild cognitive impairment, studied the effect of exercise on their NPS and compared this effect with a control group that did not follow an exercise program. Results: From 512 articles, 13 studies were included in this review, involving a total of 1,925 patients. The results were analyzed and synthesized according to the type of exercise applied – aerobic exercise, multidimensional interventions and muscular strength training programs. In particular, the results showed that repetitive aerobic exercise three to five times a week had a positive effect on NPS, whereas multidimensional interventions combining different types of exercise did not appear to be as effective. Strength training programs have been found to significantly reduce depression symptoms and behavioral problems in demented patients with mobility problems. Conclusions: There is clear evidence that physical activity and especially aerobic exercise may be effective in the management of NPS. However, it is necessary to apply specific practical recommendations and specially designed programs to incorporate physical exercise into the daily routine of these patients.

Author(s):  
Francesco Negrini ◽  
Alessandro de Sire ◽  
Stefano Giuseppe Lazzarini ◽  
Federico Pennestrì ◽  
Salvatore Sorce ◽  
...  

BACKGROUND: Activity monitors have been introduced in the last years to objectively measure physical activity to help physicians in the management of musculoskeletal patients. OBJECTIVE: This systematic review aimed at describing the assessment of physical activity by commercially available portable activity monitors in patients with musculoskeletal disorders. METHODS: PubMed, Embase, PEDro, Web of Science, Scopus and CENTRAL databases were systematically searched from inception to June 11th, 2020. We considered as eligible observational studies with: musculoskeletal patients; physical activity measured by wearable sensors based on inertial measurement units; comparisons performed with other tools; outcomes consisting of number of steps/day, activity/inactivity time, or activity counts/day. RESULTS: Out of 595 records, after removing duplicates, title/abstract and full text screening, 10 articles were included. We noticed a wide heterogeneity in the wearable devices, that resulted to be 10 different types. Patients included suffered from rheumatoid arthritis, osteoarthritis, juvenile idiopathic arthritis, polymyalgia rheumatica, and fibromyalgia. Only 3 studies compared portable activity trackers with objective measurement tools. CONCLUSIONS: Taken together, this systematic review showed that activity monitors might be considered as useful to assess physical activity in patients with musculoskeletal disorders, albeit, to date, the high device heterogeneity and the different algorithms still prevent their standardization.


2021 ◽  
pp. 111672
Author(s):  
Sandra Aires Ferreira ◽  
Angelica Miki Stein ◽  
Natã Gomes de Lima Stavinski ◽  
Denilson de Castro Teixeira ◽  
Marcos Roberto Queiroga ◽  
...  

Author(s):  
Mehrnoosh Esmailiyan ◽  
Atefeh Amerizadeh ◽  
Sahar Vahdat ◽  
Rumi Iqbal Doewes ◽  
Yamuna Sundram

2019 ◽  
Vol 1 (2) ◽  
pp. 30
Author(s):  
Niswan Helja Batubara ◽  
Nova Sylviana ◽  
Hasrayati Agustina ◽  
Hadaral Hudanul Qolbi

Cardiovascular diseases is one of the non-communicable diseases that has been the leading cause of death compared to other causes. Actually, cardiovascular diseases can be prevented with avoiding the risk factors and lifestyle improvements such as doing physical exercise. Useful physical exercise according to according to The American College of Cardiology/American Heart Association (ACC/AHA) is a moderate intensity aerobic exercise conducted 30 minutes in time for 5 days a week. This research aims to study the effects of moderate intensity aerobic exercise on macroscopic conditions, histopathologic features of the myocardium of mice. This research using 35 male balb/c mice devided to 3 groups (control, physical activity, exercise). Variables in this research included duration of physical activity and exercise, macroscopic conditions, histopathologic features of the myocardium of balb/c mice. After 10 and 28 days of exposure, the heart were harvested. The macroscopic conditions, histopathologic features of the myocardium were examined. The weight of heart in physical activity group was greater than control group (p=0.009). Similarly, the weight of heart exercise group was also greater compared to control group (p=0.013). The histopathologic features in physical activity and physical exercise groups showed pathological features of myocardial infarction (p=0.242). While in the control group did not show pathological features. Aerobic physical activity moderate intensity increase the risk of pathological condition of heart in the form of myocardial infarct through the macroscopic conditions and histological features of myocardium. Meanwhile, exercise with moderate intensity affect the physiological hypertrophy of the myocardium.


2020 ◽  
pp. 140349482091753
Author(s):  
Satu Mänttäri ◽  
Juha Oksa ◽  
Sirpa Lusa ◽  
Eveliina Korkiakangas ◽  
Anne Punakallio ◽  
...  

Aims: The potential benefits of workplace physical activity (PA) interventions are in improving both health and important workplace outcomes. Despite the differences in PA level between physically strenuous and inactive work, the literature reporting the effectiveness of the interventions does not usually differentiate physically active and inactive jobs. The aim of the current study was therefore to collect and synthesise research evidence on workplace PA interventions to promote work ability specifically among workers in physically strenuous jobs by means of a scoping review. Methods: The databases Medline, Cochrane Central and Scopus were used to identify interventions to promote work ability by increasing PA among workers in physically strenuous jobs. An iterative method was used to obtain an overview of the study elements and to extract details on the study design, sample, intervention, outcomes and effectiveness. Results: A total of 47 studies evaluating eight categories of interventions were found. Out of these, 18 reported significant effects on work ability. Positive results came from a range of different interventions, including aerobic exercise, strength training, combined aerobic exercise and strength training, stretching, yoga, consultation and tailored physical exercise programmes. Conclusions: Few interventions were effective in promoting work ability by increasing PA among workers in physically strenuous jobs. In particular, trials based on the demands of work, multimodal interventions and applying wearable technology are needed.


Author(s):  
Ellen Bentlage ◽  
Achraf Ammar ◽  
Daniella How ◽  
Mona Ahmed ◽  
Khaled Trabelsi ◽  
...  

Diminished volumes of habitual physical activity and increased sedentary levels have been observed as a result of COVID-19 home-confinement. Consequences of inactivity, including a higher mortality rate and poorer general health and fitness, have been reported. This systematic review aimed to provide practical recommendations for maintaining active lifestyles during pandemics. In May 2020, two electronic databases (PubMed; Web of Science) were used to search for relevant studies. A total of 1206 records were screened by two researchers. Thirty-one relevant studies were included in this systematic review, in which the methodological quality was assessed. With regard to six studies, which explicitly dealt with physical activity during COVID-19, the evidence level is classified by three articles to level II, and in the other three to level VI. Regarding the physical activity recommendations in these papers, three of them were classified to a medium, and the same number to a weak evidence base. Of the 25 papers which refer to other pandemics and/or isolation situations, one was classified to evidence level I, four were ranged to level II, three to level III, one to level V, and the others to level VI. This systematic review revealed that reduced physical activity levels are of serious concern during home confinement in pandemic times. The recommendations provided by many international organizations to maintain active lifestyles during these times mainly target the general population, with less consideration for vulnerable populations (e.g., older adults, people with health issues). Therefore, personalized and supervised physical activity programs are urgently needed, with the option to group-play physical activity programs (e.g., exergames). These can be assisted, delivered, and disseminated worldwide through information and communication technology solutions. If it is permitted and safe, being active outside in daylight is advised, with an effort level of mild to moderate using the rating of perceived exertion scale. Relaxation techniques should be integrated into the daily routine to reduce stress levels. On the evidence base and levels of the included articles in this review, the results need to be interpreted with caution. Given that policies are different across regions and countries, further research is needed to categorize recommendations according to different social-distancing scenarios.


2021 ◽  
Vol 79 (5) ◽  
pp. 447-456
Author(s):  
Dayanne Christine Borges Mendonça ◽  
Denise Rodrigues Fernandes ◽  
Salma Soleman Hernandez ◽  
Fernando Diákson Gontijo Soares ◽  
Karina de Figueiredo ◽  
...  

ABSTRACT Background: Neuropsychiatric symptoms are disorders frequently seen in Alzheimer's disease. These symptoms contribute to reduction of brain reserve capacity and, in addition, they present unfavorable implications, such as: poor prognosis for the disease, increased functional decline, increased burden on the caregiver and institutionalization. This scenario makes neuropsychiatric symptoms one of the biggest problems in Alzheimer's disease, and gives rise to a need for treatments focused on improving these symptoms. Sow progress in drug trials has led to interest in exploring non-pharmacological measures for improving the neuropsychiatric symptoms of Alzheimer's disease, such as physical exercise. Objective: To ascertain the effect of exercise on the neuropsychiatric symptoms of Alzheimer's disease and its implications. Methods: This was a systematic review of effective longitudinal research, conducted by searching for articles in the PubMed, Web of Science, CINAHL and Scopus electronic databases, from 2009 to 2019. Studies in which the sample consisted of elderly people aged 65 years old or over with a diagnosis of Alzheimer's disease were included. Initially 334 articles were identified. After exclusions, 21 articles remained to be read in full. From these, five articles fitted the eligibility criteria, and a further two articles were added through manual searches in the references of the articles found. Results: Out of the seven articles analyzed in this review, five studies revealed that physical exercise had a positive effect on the neuropsychiatric symptoms of Alzheimer's disease. Conclusion: This systematic review indicated that physical exercise is a favorable non-pharmacological means for attenuating the neuropsychiatric symptoms of elderly people with Alzheimer's disease, with special attention to aerobic exercises.


Author(s):  
Yunkyeong Nam

A case study was conducted in order to track the human brain adapts to changing demands by physical exercise. Reaction time and amplitude discrimination capacity of the individual were measured with the Brain Gauge to monitor brain activity before and after aerobic exercise. The objective of the study was to determine if there were short-term and/or long-term effects of aerobic exercise.  The data suggests that there are short-term effects and some improvements in performance on the tasks when comparing metrics obtained after exercise to before exercise.  For this individual, aerobic exercise was a regular part of daily routine, there was no long-term effect detected over the relatively short duration of the study.


2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Luciana Costa Melo ◽  
Jaime Dativo-Medeiros ◽  
Carlos Eduardo Menezes-Silva ◽  
Fabiano Timbó Barbosa ◽  
Célio Fernando de Sousa-Rodrigues ◽  
...  

Background. Type 2 diabetes mellitus (T2DM) is a serious disease associated with high morbidity and mortality. Scientific findings showed that physical exercise is an option for treatment of these patients. This study’s objective is to investigate the effects of supervised aerobic and/or resistance physical training on inflammatory markers in subjects with T2DM.Methods. A systematic review was conducted on four databases, MEDLINE, CENTRAL, LILACS, and Scopus, and manual search from 21 to 30 November 2016. Randomized clinical trials involving individuals diagnosed with T2DM, who have undergone supervised training protocols, were selected in this study.Results. Eleven studies were included. Studies that evaluated control group versus aerobic exercise reported controversial results about the effectiveness of physical training in modifying C-reactive protein (CRP) and cytokine levels. The only variable analyzed by the six studies in comparison to the control group versus resistance exercise was CRP. This protein showed no significant difference between groups. Between the two modes of exercise (aerobic and resistance), only one study demonstrated that aerobic exercise was more effective in reducing CRP.Conclusion. The evidence was insufficient to prove that aerobic or resistance exercise improves systemic levels of inflammatory markers in patients with T2DM.


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