scholarly journals Determinants of health-related quality of life in patients with fracture of the axis vertebrae

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andzelina Wolan-Nieroda ◽  
Andrzej Maciejczak ◽  
Mariusz Drużbicki ◽  
Agnieszka Guzik

AbstractThe study is designed to evaluate quality of life and functional performance in patients with type II and III odontoid fracture treated with anterior odontoid screw fixation. We investigated the relationship between quality of life and: (1) the range of axial rotation of the cervical spine, (2) neck pain intensity, and (3) level of disability in these patients. The study involved 60 patients operated on for type II and III fractures with the use of direct osteosynthesis of the dens. Quality of life and functional performance were assessed using SF-36 Questionnaire and Neck Disability Index (NDI). The range of axial rotation was examined with the use of the Zebris ultrasound system while the intensity of pain with the use of the VAS Visual Analog Pain Scale. The subjects’ quality of life was poorer with respect to the mental dimension (32.3%) compared to the physical dimension (22.7%). Based on the NDI survey, the rate representing the patients’ functioning in daily life amounted to 13.7% which reflects mild limitations in functional abilities. It was shown that the range of axial rotation (both to the right and the left) was not related to the degree of disability of patients as measured by the NDI questionnaire. The model of regression was statistically significant for overall quality of life (F = 48.24 p < 0.001), as well as physical dimension (F = 45.1 p < 0.001). Quality of life indicators in SF-36 are decreased in patients operated for type II and III odontoid fracture and the mental dimension of the quality of life is significantly poorer than the physical one. More than half of the patients operated for type II and III odontoid fracture regained normal functioning, as assessed with the NDI questionnaire.

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Romy Lauche ◽  
Holger Cramer ◽  
Claudia Hohmann ◽  
Kyung-Eun Choi ◽  
Thomas Rampp ◽  
...  

Introduction. Cupping has been used since antiquity in the treatment of pain conditions. In this pilot study, we investigated the effect of traditional cupping therapy on chronic nonspecific neck pain (CNP) and mechanical sensory thresholds.Methods. Fifty CNP patients were randomly assigned to treatment (TG,n=25) or waiting list control group (WL,n=25). TG received a single cupping treatment. Pain at rest (PR), pain related to movement (PM), quality of life (SF-36), Neck Disability Index (NDI), mechanical detection (MDT), vibration detection (MDT), and pressure pain thresholds (PPT) were measured before and three days after a single cupping treatment. Patients also kept a pain and medication diary (PaDi, MeDi) during the study.Results. Baseline characteristics were similar in the two groups. After cupping TG reported significantly less pain (PR: −17.9 mm VAS, 95%CI −29.2 to −6.6; PM: −19.7, 95%CI −32.2 to −7.2; PaDi: −1.5 points on NRS, 95%CI −2.5 to −0.4; allP<0.05) and higher quality of life than WL (SF-36, Physical Functioning: 7.5, 95%CI 1.4 to 13.5; Bodily Pain: 14.9, 95%CI 4.4 to 25.4; Physical Component Score: 5.0, 95%CI 1.4 to 8.5; allP<0.05). No significant effect was found for NDI, MDT, or VDT, but TG showed significantly higher PPT at pain-areas than WL (in lg(kPa); pain-maximum: 0.088, 95%CI 0.029 to 0.148, pain-adjacent: 0.118, 95%CI 0.038 to 0.199; bothP<0.01).Conclusion. A single application of traditional cupping might be an effective treatment for improving pain, quality of life, and hyperalgesia in CNP.


2017 ◽  
Vol 41 (S1) ◽  
pp. S475-S475
Author(s):  
E. Kostadinova ◽  
A. Anita

AimApproximately 30–60% of the stroke survivors suffers from depression. This, together with the physical changes after stroke may lead to a decline in their quality of life (QOL). The aim of this paper was to analyse the incidence of post-stroke depression, associated risk factors and its influence on the QOL.Material and methodsWe carried out a prospective study on stroke patients during a period of 6months. We excluded patients with dysphasia and aphasia. For each patient, we collected socio-demographic characteristics as well as clinical and therapeutic data. We used the Hamilton Depression Scale to screen for anxiety and depression, the SF-36 scale to assess the quality of life and modified Rankin scale (mRS) to measure the degree of disability.ResultsWe included 155 men and 143 women with stroke, with mean age of 58.15 years. Out of 298 analysed patients, depression was present in 147 (49.3%). Associated risk factors were hypertension, female gender and severity of stroke (P < 0.05). The mean score of the SF-36 was 52.18. Impaired QOL was found in 221 (74.1%) and mRS > 3 was found in 169 (57.1%) of the patients. Impaired mental component of QOL significantly correlated with the presence of depression (P < 0.05) and anxiety (P < 0.05). The severe degree of disability had a significant negative impact on all areas of QOL.ConclusionImportant effect after stroke is occurrence of depression which affects the QOL and functional outcome. All stroke patients should be evaluated for depression through regular interviews with them and their families or caregivers. Adequate antidepressant treatment should be given, in order to improve the QOL and physical rehabilitation.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2021 ◽  
pp. 00068-2021
Author(s):  
Aparna Balasubramanian ◽  
Robert J. Henderson ◽  
Nirupama Putcha ◽  
Ashraf Fawzy ◽  
Sarath Raju ◽  
...  

In Chronic Obstructive Pulmonary Disease (COPD), anaemia is associated with increased morbidity, but the relationship between haemoglobin over its entire observed range and morbidity is poorly understood. Such an understanding could guide future therapeutic targeting of haemoglobin in COPD management. Leveraging the COPDGene® study, we conducted a cross-sectional analysis of haemoglobin from COPD participants, examining symptoms, quality of life, functional performance, and acute exacerbations of COPD (AECOPD). Haemoglobin was analysed both as a continuous variable and categorized into anaemia, normal haemoglobin, and polycythaemia groups. Fractional polynomial modelling was used for continuous analyses; categorical models were multivariable linear or negative binomial regressions. Covariates included demographics, comorbidities, emphysema, diffusing capacity, and airflow obstruction. From 2539 participants, 366(14%) were identified as anaemic and 125(5%) as polycythaemic. Compared to normal haemoglobin, anaemia was significantly associated with increased symptoms (CAT score: p=0.006, mMRC: p=0.001), worse quality of life (SGRQ score: p<0.001, SF-36 General Health: p=0.002, SF-36 Physical Health: p<0.001), decreased functional performance (6MWD: p<0.001), and severe AECOPD (p=0.01), while polycythaemia was not. Continuous models however demonstrated increased morbidity at both ends of the haemoglobin distribution (p<0.01 for mMRC, SGRQ, SF-36 Physical Health, 6MWD, and severe AECOPD). Evaluating interactions, both diffusing capacity and haemoglobin were independently associated with morbidity. We present novel findings that haemoglobin derangements towards either extreme of the observed range are associated with increased morbidity in COPD. Further investigation is necessary to determine whether haemoglobin derangement drives morbidity or merely reflects systemic inflammation and whether correcting haemoglobin towards the normal range improves morbidity.


2020 ◽  
Vol 11 (6) ◽  
pp. 753-764
Author(s):  
Tannaz Ahadi ◽  
◽  
Gholam Reza Raissi ◽  
Maryam Hosseini ◽  
Simin Sajadi ◽  
...  

Purpose of the study: Pelvic floor muscles dysfunction is one of the most important etiologies of coccydynia, therefore, manual therapies have been proposed as the first line of treatment. The purpose of this study was to investigate the effect of biofeedback as a new approach in the treatment of coccydynia. Methods: Thirty women were randomized into two groups. Both groups were injected with corticosteroid. One group received pelvic floor muscle exercises plus biofeedback while the other only performed exercises. Patient’s pain was measured using Visual Analogue Scale (VAS) in the first visit and after 1, 2 and 6 months of follow-up as well as Dallas pain and SF-36 quality of life questionnaires before and 2 months after the treatment. Results: Pain had improved significantly after 1, 2 and 6 months in both groups compared to the baseline. However, the amount of change was not different between the groups at any time interval. The results were the same for Dallas pain scale and SF-36 quality of life questionnaire. Conclusion: Adding biofeedback to pelvic floor muscle exercises did not lead to any further improvement in management of chronic coccydynia. Further studies with larger sample sizes may show the effect of biofeedback more clearly.


Author(s):  
Carlos Barbosa Torres ◽  
Sixto Cubo Delgado ◽  
Florencio Vicente Castro

Abstract.SIMULATION OF SYMPTOMS IN PATIENTS WITH FIBROMYALGIAIn this paper we find a study about the variable of simulation of symptoms in fibromyalgia syndrome regarding to other psychological variables such as quality of life, depression, anxiety as well as gradation of pain. The study was performed with 40 patients, all diagnosed with fibromyalgia by the criteria of the American Rheumatology Association. The instruments used were the Structured Inventory of Malingered Symptomatology (SIMS), the Graded Chronic Pain Scale and SF-36 Health Survey (SF-36v2). The results show that there is a relationship between the simulation of symptoms and chronic pain but not with quality of life. The simulation of symptoms in patients with fibromyalgia is a very complex phenomenon that depends on several methods of control among which it is possible to emphasize the use of screening like the SIMS supported with important physical and psychological examinations by experts.Key words: Fibromyalgia, chronic pain, symptom simulation.Resumen.En el presente trabajo encontramos un estudio sobre la variable simulación de síntomas en pacientes con fibromialgia en relación con otras variables psicológicas como calidad de vida, depresión y ansiedad al igual que la gradación del dolor. El estudio se realizó con un total de 40 pacientes todos diagnosticados con fibromialgia por los criterios de la Asociación Americana de Reumatología. Los instrumentos utilizados fueron, el Inventario Estructurado de Simulación de síntomas (SIMS), el Graded Chronic Pain Scale y el SF-36 Health Survey (SF-36v2) o Cuestionario autogestionado de Salud SF-36. Los resultados expuestos muestran que existen relación entre la simulación de síntomas dolor crónico pero no con la calidad de vida. La simulación de síntomas en pacientes con fibromialgia es un fenómeno muy complejo que depende de varios métodos de control entre los que cabe destacar la utilización de screening como el SIMS apoyados con importantes exámenes físicos y psicológicos por expertos.Palabras clave: Fibromialgia, dolor crónico, simulación de síntomas.


2016 ◽  
Vol 29 (3) ◽  
pp. 589-596 ◽  
Author(s):  
Grazielle Cordeiro Aguiar ◽  
Samira Gonçalves Rocha ◽  
Gisele Aparecida da Silva Rezende ◽  
Marcela Rêgo do Nascimento ◽  
Paula Luciana Scalzo

Abstract Introduction: Osteoarthritis (OA), the most common form of arthritis, is considered the main cause of pain and disability in the elderly. Objective: To evaluate the effect of systematic muscle strength training on functional performance and quality of life in individuals with knee OA. Methods: Subjects with knee OA (n = 27, 46 - 76 years) completed the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Medical Outcomes Short-Form 36-item Health Survey (SF-36), and visual analog scale (VAS) questionnaires, musculoskeletal assessments, and 10-repetition maximum and timed 10-meter walk tests both before and after training. The training consisted of an exercise resistance program and stretches for 12 weeks (three sessions of 80 each per week). Results: Twenty-two subjects completed the training. Reduced overall scores and WOMAC physical function indicated improved functional performance (p < 0.001) as well as increased gait speed (p < 0.001). The perception of pain decreased after training, as evidenced by the VAS, WOMAC pain domain, and SF-36 scores (p < 0.001). Quality of life improvements occurred primarily in the areas of pain, functional capacity, and SF-36 physical aspects. No change in body mass index was noted (p = 0.93). Conclusion: Our results indicate that the combination of resistance training for the quadriceps, gluteus, and abdominal muscles could be a viable alternative to improving functionality and quality of life in patients with knee OA. However, more studies are necessary to confirm our findings.


2021 ◽  
Author(s):  
Zainab Abdulameer Abdulrasol

Primary dysmenorrhea (PD) is a painful menstrual flow in the absence of any pelvic pathology where pain is spasmodic in character and felt mostly in the lower abdominal area. PD considered as common problem in females at reproductive age, it’s directly affects the quality of life (QoL). The main objective of this study is to find out the relationship between PD and QoL of among female students. Descriptive correlational study design carried out on (145) female students, purposive sampling, and their ages between (18–25) years, participants were selected from four faculties at the University of Babylon. Numeric rating pain scale (11-point scale) was used for assessing pain intensity, QoL has been assessed by the SF-36 health survey (SF-36). Data have been collected by using a structured interview as method of data collection and using questionnaire as study tool. Data were processed and analyzed by using SPSS version (25). The findings of the present study revealed that (62.1%) of respondents reported as severe primary dysmenorrhea. The greatest proportion of female students with fair QoL and (17.9%) with poor QoL. The study’s finding finds out a negative significant correlation between PD intensity and overall QoL scale at P ≤ 0.05 (r = − 0.642, P = 0.000).


2021 ◽  
Vol 29 (3) ◽  
pp. 549-560
Author(s):  
Carlos Barbosa-Torres ◽  
Sixto Cubo-Delgado

The objective of the study was to analyze how the brain shaping provided by the sensorimotor rhythm protocol (SMR), applied on somatosensory areas, affects pain, sleep and the quality of life in women with fibromyalgia. Thirty-seven women with fibromyalgia who received an SMR protocol in 20 sessions participated and were evaluated before and after treatment. The data showed an increase in the amplitude of the SMR (p= .026) and a decrease in the amplitude of the theta band (p= .011) in the somatosensory cortex after the application of therapy, which caused an increase in the SMR/theta ratio (p= .048). In addition, the scores on the Chronic Pain Scale (p= .002), the Pittsburgh Sleep Quality Index (p= .001), and the SF-36 Health Survey (p= .000) improved significantly. The SMR protocol applied to the somatosensory cortex favors the shaping of SMRs, which has an impact on stimulating the inhibition of the central nervous system of patients with fibromyalgia, improving symptoms such as pain, sleep, and quality of life.


Neurosurgery ◽  
2020 ◽  
Author(s):  
Suzanne McIlroy ◽  
Jordan Lam ◽  
Muhammad Faheem Khan ◽  
Asfand Baig Mirza ◽  
Jerry Ajayi Philip ◽  
...  

Abstract BACKGROUND Type II odontoid fractures are a common cervical fracture in older people. Lower osseous-union rates are reported in those treated conservatively compared to surgically; however, the clinical relevance of a nonunion is unknown. OBJECTIVE To compare pain, disability, and quality of life in older people following conservative management of type II odontoid fractures demonstrating osseous-union and nonunion. METHODS Electronic records were searched from 2008 to 2018 for adults ≥65 yr with type II odontoid fracture, managed in a semi-rigid collar. Clinical and demographic data were retrieved from electronic patient notes. Surviving patients were invited to complete questionnaires to assess pain, disability, and quality of life. Ethical approval was granted. RESULTS A total of 125 patients were identified: 36 (29%) demonstrated osseous-union, 89 (71%) had nonunion, of which 33 (40%) had radiological instability. Mean age at fracture was 84 yr (osseous-union 83 yr; nonunion 84 yr). A total of 53 had deceased (41 nonunion). Median length of survival was 77 mo for osseous-union vs 50 mo for nonunion; P = .02. No patient developed myelopathy during the follow-up period. Questionnaire response rate was 39 (58%). There were no statistically significant differences between the groups in terms of pain, disability, or quality of life (P &gt; .05). Both groups reported mild disability and pain but low quality of life. CONCLUSION Management with a semi-rigid collar in older people with type II odontoid fracture is associated with low levels of pain and disability without statistically significant differences between those demonstrating osseous-union or stable or unstable nonunions. Conservative management appears to be a safe treatment for older people with type II fractures.


Author(s):  
G. N. Chuprуna

We studied the quality of life (QoL) in patients with multiple sclerosis (MS) with the SF-36 compared to the control groups and in terms of comorbidity, as well as to determine the correlation between QoL and the degree of disability, the level of severity of fatigue, depression, pain, disorders of cognitive functions. The study involved 205 MS patients with different forms of course and 157 people made up the control group. Evaluated the clinical and demographic characteristics of the patients with MS due to comorbidity, determines the level of disability (EDSS), severity of pain (VAS), the severity of fatigue (FSS), depression (BDI-II), cognitive impairment (MMSE), quality of life ( SF -36 One or more concomitant disease was detected in 102 (49.3%) patients with MS, there was no co-morbidities in 105 (50.7%) patients with MS. It has been found that in patients with MS I and II groups QoL were significantly lower compared with controls both the individual scales, and by generalized indicators. Also found that during the correlation analysis between QoL and data EDSS, FSS, BDI-II, VAS and MMSE in patients with MS I and II the closest correlations were observed between the indices of quality of life and EDSS, and the least close - between QoL and MMSE. The most informative in establishing correlations between QoL and data EDSS, FSS, BDI-II, VAS and MMSE in patients with MS I and II according to our information was the scale of VT and generalized indicators MH and PH, and the least informative - the scale of GH. Also, it was found that the maximum reduction of generalized QoL in patients with MS group II (relative to the average for the group II) was associated with policomorbidity.  


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