Mesoporous carbon derived from vitamin B12: a high-performance bifunctional catalyst for imine formation

2016 ◽  
Vol 52 (3) ◽  
pp. 481-484 ◽  
Author(s):  
Bo Chen ◽  
Sensen Shang ◽  
Lianyue Wang ◽  
Yi Zhang ◽  
Shuang Gao
Keyword(s):  
Vitamin B12 ◽  
Organic Synthesis ◽  
Mesoporous Carbon ◽  
High Performance ◽  
Cross Coupling ◽  
Bifunctional Catalyst ◽  
The Self ◽  
Primary Amines ◽  
Vitamin B ◽  
First Time

Mesoporous carbon derived from natural vitamin B12 is applied for the first time in organic synthesis and exhibits exceptionally high dual activity for imine formation via the cross-coupling of alcohols with amines and the self-coupling of primary amines.

scholarly journals Estimation of vitamin B12 in plasma by High Performance Liquid Chromatography

2017 ◽  
Vol 12 (3) ◽  
pp. 251 ◽  
Author(s):  
Fahmida Hasnat ◽  
Habiba Akhter Bhuiyan ◽  
Mir Misbahuddin
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Vitamin B12 ◽  
High Performance ◽  
Plasma Sample ◽  
Video Clip ◽  
Deionized Water ◽  
Vitamin B ◽  
Blood Plasma Sample ◽  
Full Screen

<p>High performance liquid chromatography was used to develop and validate the detection of vitamin B<sub>12</sub> in blood plasma sample. The mobile phase consists of a mixture of 0.025% trifluroacetic acid in deionized water and 30% methanol. The mixture used was adjusted to pH 2.9 and the flow rate was adjusted to 0.5 mL/min. The separation was achieved using C18 column maintained at 30ºC temperature and detection of vitamin B<sub>12</sub> was conducted at maximum wavelength 230 nm.</p><p><strong>Video Clip of Methodology</strong>:</p><p>Estimation of vitamin B12 in plasma by HPLC: 4 min 29 sec   <a href="https://www.youtube.com/v/0eMxqsdDtlE">Full Screen</a>   <a href="https://www.youtube.com/watch?v=0eMxqsdDtlE">Alternate</a></p>

Nanosized LiNi1−xFexPO4embedded in a mesoporous carbon matrix for high-performance electrochemical water splitting

2015 ◽  
Vol 51 (87) ◽  
pp. 15815-15818 ◽  
Author(s):  
Shaojun Ma ◽  
Qing Zhu ◽  
Zhi Zheng ◽  
Wenlou Wang ◽  
Dongming Chen
Keyword(s):  
Water Splitting ◽  
Oxygen Evolution ◽  
Oxygen Evolution Reaction ◽  
Mesoporous Carbon ◽  
High Performance ◽  
Carbon Matrix ◽  
Highly Effective ◽  
Electrochemical Water Splitting ◽  
First Time ◽  
Electrochemical Oxygen

This work reports for the first time LiNi1−xFexPO4@C nanocomposites as highly effective catalysts for electrochemical oxygen evolution reaction (OER).

Recent developments in arylation of N-nucleophiles via Chan-Lam reaction: updates from 2012 onwards

2021 ◽  
Vol 17 ◽  
Author(s):  
Fahimeh Abedinifar ◽  
Mohammad Mahdavi ◽  
Elham babazadeh Rezaei ◽  
Mehdi Asadi ◽  
Bagher Larijani
Keyword(s):  
Organic Synthesis ◽  
Room Temperature ◽  
Cross Coupling ◽  
Recent Decade ◽  
Boronic Acids ◽  
Research Progress ◽  
Wide Range ◽  
Recent Developments ◽  
Comprehensive Survey ◽  
First Time

: ''Chan-Evans-Lam'' (CEL) reaction is the copper-mediated cross-coupling of N-nucleophiles with boronic acids that was independently reported in 1998 by Chan, Evans, and Lam for the first time. This reaction is accomplished at room temperature with a remarkably wide range of nucleophiles. In the recent decade, it has been particularly attractive as a convenient method for constructing the various C–N bonds in organic synthesis. Therefore, a comprehensive survey through all reported process was crucial. In this review, we summarized research progress about N-Arylation, based on the type of N-nucleophile involved in this reaction and catalysts from 2012 onwards.

Bio-inspired chitosan-heme-vitamin B12-derived Fe–Co bimetallic-doped mesoporous carbons for efficiently electro-activating oxygen

2019 ◽  
Vol 48 (7) ◽  
pp. 2338-2344 ◽  
Author(s):  
Zifan Ma ◽  
Longdi Xu ◽  
Luyao Liu ◽  
Luyao Wang ◽  
Xiaoying Zhang ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Mesoporous Carbon ◽  
Oxygen Electroreduction ◽  
Molecular Structures ◽  
Vitamin B ◽  
Mesoporous Carbons ◽  
Co Doped

Biomass-derived chitosan-heme-vitamin B12 with definitive molecular structures was converted to bimetallic Fe–Co-doped mesoporous carbon for efficient oxygen electroreduction.

scholarly journals Mesoporous Carbon of Carbonized Human Urine Waste: A Valuable Heterogeneous Catalyst for Chromene and Xanthene Derivative Synthesis

Catalysts ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1369
Author(s):  
T. A. J. Siddiqui ◽  
Shoyebmohamad F. Shaikh ◽  
Sushil S. Sangale ◽  
Siddheshwar D. Raut ◽  
Rajaram S. Mane ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Organic Synthesis ◽  
Human Urine ◽  
Mesoporous Carbon ◽  
Catalytic Performance ◽  
Morphology Evolution ◽  
One Pot ◽  
Simple Method ◽  
Crystalline Nature ◽  
First Time

Human urine is universal unused waste material that is regularly disposed of by the human body. We, for the first time, presented an economically beneficial, sustainable, and novel route to synthesize mesoporous human urine carbon (HUC)-containing heteroatoms, i.e., C, Na, Cl, N, S, and P, using a human urine waste. The as-synthesized HUC were envisaged for their structural elucidation, morphology evolution, crystal structure, functional bonding, and elemental composition analyses through various sophisticated technologies. The HUC catalyst had a moderately crystalline nature due to the graphitic phase of carbon with a particle size of 20–50 nm, which was successfully used to synthesizing chromenes, 1,8-di-oxo-octahydroxanthenes, and benzypyrazolylcoumarin and biscoumarin derivatives through a one-pot multicomponent reaction with 20 mg of catalyst in EtOH/H2O solvent. This eco-friendly and simple method offers numerous advantages such as easy purification, clean reaction, and excellent yield for organic synthesis. The HUC catalyst can be recycled ten times and reused multiple times after activation without affecting catalytic performance.

Superionic Lithium Intercalation through 2 nm x 2 nm Columns in the Crystallographic Shear Phase Nb18W8O69

2019 ◽  
Author(s):  
Kent Griffith ◽  
Clare Grey
Keyword(s):  
High Performance ◽  
Rate Capability ◽  
Block Size ◽  
Lithium Intercalation ◽  
Resonance Spectroscopy ◽  
Complex Metal Oxides ◽  
Battery Electrode ◽  
Crystallographic Shear ◽  
Battery Material ◽  
First Time

Nb18W8O69 (9Nb2O5×8WO3) is the tungsten-rich end-member of the Wadsley–Roth crystallographic shear (cs) structures within the Nb2O5–WO3 series. It has the largest block size of any known, stable Wadsley–Roth phase, comprising 5 ´ 5 units of corner-shared MO6 octahedra between the shear planes, giving rise to 2 nm ´ 2 nm blocks. Rapid lithium intercalation is observed in this new candidate battery material and 7Li pulsed field gradient nuclear magnetic resonance spectroscopy – measured in a battery electrode for the first time at room temperature – reveals superionic lithium conductivity. In addition to its promising rate capability, Nb18W8O69 adds a piece to the larger picture of our understanding of high-performance Wadsley–Roth complex metal oxides.

The Total Synthesis of Rhabdastrellic Acid A

2018 ◽  
Author(s):  
Yaroslav Boyko ◽  
Christopher Huck ◽  
David Sarlah
Keyword(s):  
Total Synthesis ◽  
Late Stage ◽  
Cross Coupling ◽  
Side Chains ◽  
General Strategy ◽  
Modular Approach ◽  
Linear Sequence ◽  
Generating Sequence ◽  
First Time

<div>The first total synthesis of rhabdastrellic acid A, a highly cytotoxic isomalabaricane triterpenoid, has been accomplished in a linear sequence of 14 steps from commercial geranylacetone. The prominently strained <i>trans-syn-trans</i>-perhydrobenz[<i>e</i>]indene core characteristic of the isomalabaricanes is efficiently accessed in a selective manner for the first time through a rapid, complexity-generating sequence incorporating a reductive radical polyene cyclization, an unprecedented oxidative Rautenstrauch cycloisomerization, and umpolung 𝛼-substitution of a <i>p</i>-toluenesulfonylhydrazone with in situ reductive transposition. A late-stage cross-coupling in concert with a modular approach to polyunsaturated side chains renders this a general strategy for the synthesis of numerous family members of these synthetically challenging and hitherto inaccessible marine triterpenoids.</div>

Microwave Assisted Organic Synthesis: Cross Coupling and Multicomponent Reactions

2013 ◽  
Vol 17 (5) ◽  
pp. 474-490 ◽  
Author(s):  
Amit Kumar Gupta ◽  
Neetu Singh ◽  
Krishna Nand Singh
Keyword(s):  
Organic Synthesis ◽  
Multicomponent Reactions ◽  
Cross Coupling ◽  
Microwave Assisted

Development of an HPLC-UV Method for Quantification of Stattic

2019 ◽  
Vol 15 (6) ◽  
pp. 568-573
Author(s):  
Soheil Sedaghat ◽  
Ommoleila Molavi ◽  
Akram Faridi ◽  
Ali Shayanfar ◽  
Mohammad Reza Rashidi
Keyword(s):  
High Performance ◽  
Accurate Method ◽  
Plasma Samples ◽  
Promising Target ◽  
Relative Standard ◽  
Dimerization Inhibitor ◽  
Oncogenic Protein ◽  
First Time ◽  
Transcription 3

Background: Signal transducer and activator of transcription 3 (STAT3), an oncogenic protein found constitutively active in many types of human malignancies, is considered to be a promising target for cancer therapy. Objective: In this study for the first time, a simple and accurate method has been developed for the determination of a STAT3 dimerization inhibitor called stattic in aqueous and plasma samples. Methods: A reverse-phase high-performance liquid chromatography (RP-HPLC) composed of C18 column as stationary phase, and the mixture of acetonitrile (60%) and water (40%) as mobile phase with a UV detection at 215 nm were applied for quantification of stattic. The developed method was validated by Food and Drug Administration (FDA) guideline. Results: The method provided a linear range between 1-40 and 2.5-40 µg mL-1 for aqueous and plasma samples, respectively, with a correlation coefficient of 0.999. The accuracy (as recovery) of the developed method was found to be between 95-105% for aqueous medium and 85-115% for plasma samples. The precision (as relative standard deviation) for aqueous and plasma samples was less than 6% and 15%, respectively. The sensitivity of the developed method based on FDA guideline was 1 µg mL-1 for aqueous and 2.5 µg mL-1 for plasma samples. Conclusion: These results show that the established method is a fast and accurate quantification for stattic in aqueous and plasma samples.

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