scholarly journals Constitutional factors of autarcesis of the Orenburg goats

2021 ◽  
Vol 282 ◽  
pp. 03016
Author(s):  
S.V. Nikitina
Keyword(s):  
Blood Serum ◽  
Bactericidal Activity ◽  
White Blood Cells ◽  
Lysozyme Activity ◽  
Lytic Activity ◽  
Humoral Factors ◽  
Group Breeding ◽  
Winter Time ◽  
Summer Time ◽  
Experimental Group

The paper shows the results of a comparative assessment of the seasonal and age patterns of autarcesis in Orenburg goats. Intact healthy goats were studied as control groups: 1st experimental group - breeding male goats (n=10), 2nd group – breeding female goats (n=10), 3rd experimental group - gimmer hogs (n=10), and 4th experimental group - young wethers (n = 10). The autarcesis is marked by humoral factors, for example, indicators of the bactericidal activity of the blood serum, lysozyme activity, and beta-lytic activity (thrombodefensin activity). The investigations have shown that the maximum values of the bactericidal activity of the blood serum were found in the autumn and winter times in the experimental groups. Their values were 73,75±1,07 %, 78,28±0,85 %, 65,89±1,16 %, and 71,16±0,71 %, respectively. The minimum values are determined in spring and summer. A similar pattern was found in the study of beta-lytic activity in the autumn-winter time, but the highest values were observed in the animals of the experimental group of 9.43±0.12% and 9.86±0.15 %, respectively. The decrease in the bactericidal activity of the blood and the beta-lytic activity in the summer time was recompensed by the values of lysozyme activity. Thus, the highest immunological indices were found in summer time. The highest values of white blood cells were found in the blood of the gimmer hogs and young wethers. Meanwhile, the studied indicators did not overstep the limits of the physiological standard. The data obtained are suggested to be used in breeding work for the reproduction of animals with a high level of autarcesis.

scholarly journals THE EFFECT OF «ARCUSIT» ON BIOCHEMICAL AND IMMUNOLOGICAL PARAMETERS BLOOD SERA IN SILVER-BLACK FOX (SILVER-BLACK FOX)

2021 ◽  
Vol 247 (3) ◽  
pp. 192-197
Author(s):  
I.I. Okulova ◽  
◽  
I.A. Domsky ◽  
Yu.A. Berezina ◽  
Z.N. Beltyukova ◽  
...  
Keyword(s):  
Experimental Data ◽  
Blood Serum ◽  
Bactericidal Activity ◽  
Lysozyme Activity ◽  
The Body ◽  
Phagocytic Index ◽  
Control Group ◽  
Immunological Parameters ◽  
Nonspecific Resistance ◽  
Experimental Group

The use of «Arkusit» at a dose of 20 μg / kg of body weight indicates a beneficial effect on the factors of nonspecific resistance of the silver-black fox. The concentration of alkaline phosphatase in the blood serum in the experimental group decreased by 1.8 times (P <0.001), the ALT index - by 1.2 (P <0.05). The concentration of glucose in the experimental group increased 2 times (P <0.05) compared with the control group. In animals of the experimental group, the lysozyme activity of blood serum increased 1.3 times (P <0.05), the OPR reaction and the phagocytic index - 1.4 times (P <0.05), the bactericidal activity of blood serum - 1.8 times (P <0.05). «Arcusit» stimulates the synthesis of gamma globulins, increases the opsonophagocytic, bactericidal activity of blood serum. Thus, the analysis of experimental data indicates that the drug «Arcusit» has a pronounced immunostimulating effect, providing the activation of factors of nonspecific resistance of the body of the silver-black fox.

scholarly journals The cell protection of weated pigs for probiotics

2020 ◽  
pp. 111-119
Author(s):  
L. Bondarenko
Keyword(s):  
Immune System ◽  
Blood Serum ◽  
Phagocytic Activity ◽  
Lysozyme Activity ◽  
The State ◽  
Natural Resistance ◽  
Phagocytic Index ◽  
Control Group ◽  
Stressful Situation ◽  
Experimental Group

The immune system is central to ensuring the consistency of the body's homeostasis. The state of the body's natural resistance is determined by a set of non-specific protective mechanisms. Lymphocytes and phagocytes are actively involved in maintaining immunity. Lymphocytes recognize the antigens of pathogenic microorganisms, and phagocytes absorb and destroy the pathogens themselves. During the weaning of piglets from sows there is a decrease in the protective forces of their body. During this period, the natural resistance of the piglets is reduced due to the stressful situation caused by changing conditions of confinement, the transition to full feed and lack of sows. The immune system of weaning pigs is relatively weak, so when exposed to environmental and technological stressors, they become susceptible to various diseases. The use of probiotic drugs stimulates the activity of the immune system, prevents stress and immunodeficiency. One of these probiotics is the probiotic of domestic production Protecto-active. It w observed the the influence of the probiotic Protecto-active on the indices of nonspecific resistance of the young pigs organism to the growth. An increase in bactericidal activity of blood serum by 12.10% (P <0.05) and lysozyme activity of blood in the piglets of the experimental group was increased by 3.71% compared to control, which indicates the activation of the body's defenses and the increase in adaptive capacity. An important step in the study of the influence of the probiotic Protekto-active on the state of the immune system is to determine the phagocytic activity of neutrophils, phagocytic index and phagocytic number. In the experimental group of piglets that were fed the probiotic Protecto-active, we found an increase in leukocyte phagocytic activity by 9.0% (P <0.001), a phagocytic index by 51.7% (P<0.001) and a phagocytic number by 24.8% ( P <0.01) compared with the control group. Thus, using a probiotic Protecto-active, all indicators of phagocytosis increase: the number of phagocytes increases, their ability to capture microorganisms and increases their digestive capacity, it increases the bacterial and lysozyme activity of blood serum, which is positively reflected in the immunobiosity. Key words: probiotic, phagocytosis, phagocytic index, phagocytic number, phagocytic activity of leukocytes, cellular immunity, piglets

scholarly journals РЕЗИСТЕНТНІСТЬ І ПРОДУКТИВНІСТЬ КРОЛІВ ПРИ ВИКОРИСТАННІ ПРОБІОТИКА «ЕВІТАЛІЯ» В УМОВАХ НОРМАТИВНОГО МІКРОКЛІМАТУ

2016 ◽  
Vol 18 (2(66)) ◽  
pp. 192-197
Author(s):  
N.V. Cherny ◽  
V.V. Kulak
Keyword(s):  
Blood Serum ◽  
Average Daily Gain ◽  
Live Weight ◽  
Lysozyme Activity ◽  
The Body ◽  
Immunological Parameters ◽  
Humoral Factors ◽  
Regulatory Climate ◽  
Cellular Factors ◽  
Definition Of

The influence of probiotic «Evitaliya» hematological, biochemical and immunological parameters of the giant white rabbits in terms of regulatory climate. The studies were performed on young rabbits from birth until 120 days of age, two groups of animals. Experienced groups asked the drug twice a day for 25 ml per head from birth to 30 days of age, and then 50 ml on the head (from 31 – to 90– day age). To assess the effect of the probiotic on the body of the rabbit used hygienic methods of research (definition of temperature and humidity, bacterial obremenjenosti air, light); clinical (body temperature, pulse rate and respiration); hematological (erythrocytes, hemoglobin, leukocytes); immunological (bactericidal and lysozyme activity of blood serum, phagocytes index, phagocytes activity of neutrophils (FAN); livestock (live weight and SSP), statistical.Studies found that the use of rabbits with probiotic ferment «Evitaliya» in doses of 25 ml per head and 50 ml / head twice a day for 5 days with breaks of 10 the bottom, contribute to the activation of redox processes in the intestine and the body as a whole, stimulation of humoral and cellular factors of protection, the intensive growth. The studies revealed the following:– increased in the blood of rabbits (age 10–30–60 days) red blood cell count 8.8 – 9.2%, leucocytes – 4,7 – 5,1%, the concentration of hemoglobin – 5.3 – 7.1 per cent– increased humoral factors of protection up to: bactericidal activity of blood serum – to 36.46,0 ± 0.38 – of 55.15 ± 0.40 percent, lysozyme activity of blood serum to 36.14 ± 0.79 – 40.18 ± 0.83;– cellular factors of protection: the phagocytes index from 17 to 19,8%, phagocytes activity of neutrophils – 10.1 – 11.4 per cent;– manifested stimulating effect on live weight and average daily gain from the use of probiotic «Evitaliya».

scholarly journals Productivity and resistance of pigs under the action of immunostimulants

2017 ◽  
Vol 19 (79) ◽  
Author(s):  
N. V. Chorniy ◽  
O. S. Machula ◽  
V. V. Voronyak ◽  
V. P. Lyasota ◽  
O. P. Reshetnichenko
Keyword(s):  
Blood Serum ◽  
B Lymphocytes ◽  
Live Weight ◽  
The Body ◽  
Control Group ◽  
Average Weight ◽  
Large White ◽  
Immunological Parameters ◽  
Humoral Factors ◽  
Experimental Group

The aim of the work was to study the influence of stimulant drugs – the regenerating biological stimulant (RBS) and Imunolac on the immunological state and productive qualities of piglets. RBS is a complex of organic compounds of animal tissue that stimulates nonspecific immunity and increases the protective functions of the body. Imunolac is a preparation of enzymatic hydrolysis of the cell wall of Lactobacillus, activating the cellular and humoral factors of non-specific animal resistance. To achieve this goal, the following tasks were set: to find out the microclimate condition and sanitary regime in the boxes in which the experimental animals were kept; – to study the influence of immunostimulating drugs on the growth and intensity of the test pigs, their safety; to study the dynamics of immunological parameters (circulating immune complex (CIC), T-and B-lymphocytes), the content of immunoglobulins (Jg G, Jg M and Jg A) while using RBS and Imunolac. The research was carried out in the pedigree plant «Stepnoy» of the Zaporozhye region on pigs of the Large white breed × Landras. Piglets of the control group were injected with 0.9% sodium chloride solution at a dose of 1 ml/head. During the experiment, the microclimate was monitored for temperature, relative humidity, air speed, carbon dioxide, ammonia, air contamination with microflora. Cellular indices were determined from the ratio of neutrophils to E. coli according to VG Gostivu, 1956, bactericidal activity of blood serum (BASK) – according to the method of O.V. Smirnova and TA. Kuzmenoy, 1966, lysozyme activity of blood serum (LASK) according to V. Dorofeychuk, 1968. The content of T lymphocytes was determined according to M. Jondal, 1973, B-lymphocytes – according to N.S. When piglets were grown at the temperature lower than 3,5–8 °C, humidity – by 5–8% higher, the parameters of NH3 and CO2 higher by 0.8–1.2%, the contamination microflora was twice as much as recommended by the sanitary norms the genetic productive potential of the animals is not fully realized, while – the highest daily average weight gain was in the pigs, which were injected intramuscularly with RBS growth stimulant. They exceeded the animals from the control group on the 20th and 30th days of the experiment – by 24.3% and 14.4%, live weight – by 15.3% (P < 0.05). The growth rate in the animals that were injected with imunolac was less expressed; the diseases with the symptoms of dyspepsia and bronchopneumonia were registered in 5–10% of the pigs from the experimental groups that received RBS and imunolac that is 10–12 times less as compared to the control group; in the pigs from the experimental group 1, the BASK was at the level of the average values of 56.52 ± 2.03%, from the experimental group 2 – 59.48 ± 1.80%, by 5.2% higher (P < 0.05); LASK indices in the animals of the experimental group tended to increase but the differences were not trustworthy (P < 0.5); the cell indices of resistance in the pigs that received RBS were higher: the phagocytic activity of blood serum – by 4.3% (P < 0.05), phagocytic number – by 9.7% (P <0.05); the highest concentration of immunoglobulin of class Jg G (21.82 ± 0.3 mg/ml) was revealed in the animals that received RBS preparations, the concentration of the above immunoglobulins was slightly below – 19.86 ± 0.18 mg/ml in the pigs that received imunolac (0–1). For immunoglobulins of class Jg M and Jg A, the fluctuations  between the experimental groups were within the limits of 2.23 ± 0.01 and 2.36 ± 0.09 mg/ml.

THE STATE OF INNATE IMMUNITY IN NORMOTROPHIC PIGLETS IN THE EARLY POSTNATAL PERIOD

1970 ◽  
pp. 65-69
Author(s):  
A. G. Shakhov ◽  
S. V. Shabunin ◽  
L. Yu. Sashnina ◽  
M. Yu. Zheynes ◽  
Yu. Yu. Vladimirova ◽  
...  
Keyword(s):  
Bactericidal Activity ◽  
Total Protein ◽  
White Blood Cells ◽  
Postnatal Period ◽  
Lysozyme Activity ◽  
Immune Defense ◽  
Nonspecific Immunity ◽  
Age Related ◽  
Nbt Test ◽  
Existence Conditions

The article presents the dynamics of changes in the performance of hematological, biochemical, humoral and cellular components of nonspecific immunity in normotrophic piglets from its birth to weaning from sows. The age-related changes in the performance in all the components of nonspecific immunity in piglets, connected with the adaptation of the organism to the new existence conditions and the activation of the duties of their organs and systems, have been established. In the hematological component, the changes were manifested by a higher content of white blood cells and lymphocytes in piglets, starting from the daily age and in the following terms of cultivation, relative to such before intake of colostrum. For the biochemical state of piglets before intake of colostrum, the most definitive were low total protein, but high albuminous and high nitrogen oxide, essential to the adaptation of animals to new existence conditions, Hypoglobulinemia. In piglets, starting from the daily age, the total protein, globulins, and especially gamma globulins, promoting the humoral defense, are increased, and the albuminous is decreased. The humoral performance of non-specific defense for piglets before colostrum intake is characterized by a low activity of the complement system, which increases up to 14 days-age, followed by its thereafter decrease. Serum bactericidal activity is decreased on the 22nd, and lysozyme activity - on the 26th day of age. From the daily age and in the days following, neutrophil phagocytic activity; stimulated NBT test, and phagocyte reserve number exceeded like that before intake of colostrum. Absorbtivity of neutrophils and spontaneous NBT test increased only in daily age piglets. The lowest level of nonspecific immune defense in piglets during the last week of the suckling period, manifested by a decrease of the bactericidal activity, of lysozyme activity, and of complementary activity of blood serum, of monocytes, and of gamma-globulins, is due to a decrease in sow productivity.

scholarly journals Stress state and immunological status of young pigs

2019 ◽  
pp. 95-98
Author(s):  
M. V. Chornyi
Keyword(s):  
Stress State ◽  
Blood Serum ◽  
Bactericidal Activity ◽  
Total Protein ◽  
Live Weight ◽  
Natural Resistance ◽  
Control Group ◽  
Immunological Status ◽  
Young Pigs ◽  
Experimental Group

The paper presents the results of studies on the effect of regrouping of piglets at different ages on the resistance of their organisms, immunological status, productive qualities and safety of young pigs. The work was performed at “Stas” LLC on large white breed pigs and their crossbreeds. For the experiment, three groups of piglets were formed from suckling sows — analogues. In the experiment 60 animals from birth up to two months of age were used, 20 animals in each experimental group. The control group of piglets was raised from birth up to 60 days of age in nests, and then they were moved to the rearing workshop; Experimental 1 group was kept up to 10 days old in nests, and then a one-time rearrangement was performed according to live weight. Piglets from experimental group 2 were regrouped according to live weight at 5, 10, 15, 21, 30 days of age. To assess the natural resistance of piglets due to the above groups, hematological, biochemical (total protein, protein fractions) methods, immunological (immunoglobulins of classes IgA, IgM, IgG), and natural resistance (bactericidal activity of blood serum) were used, serum lysozyme activity (LASK), phagocytic neutrophil activity (FAN), phagocytic index (FI), ethological, zootechnical, mathematical. To assess the natural resistance of piglets the following research methods were used: generally accepted zoo veterinary methods (live weight, morbidity, safety), hygienic (microclimate conditions, sanitary regime), hematological (morphological blood composition), biochemical (total protein, protein fractions), immunological (immunoglobulins of classes IgA, IgM, IgG), natural resistance (bactericidal activity of blood serum), ethological and mathematical methods. Results of work. It was found that when growing piglets, nesting, without moving, caused their growth and development without any noticeable physiological disturbances, both from the blood and ethology. In animals (Experimental-1 groups) which underwent a single regrouping in a 10 day reward, their lag in live weight by 12.65% was recorded, compared with the control, with two and three-time movement (Experimental-2) — by 16.10%. Their SSPs were 28% less and 14.7% lower than in the control piglets. Patients with symptoms of diarrhea were identified in the control: in 3–4 daily reimbursement — 1%, in Experimental-1 — 5%, Experimental-2 — 10–15%. The resistance of young animals to gastrointestinal diseases according to the Melenberg coefficient in the Experimental-2 group was 6.13–7.48, in control group it was 0.34, and the safety did not exceed 80.2%. According to the level of immune status, animals from Experimental-2 group were inferior: by BASK — by 25.15% (28 days of age), by LASK — by 7.56%, by FAN — by 10.7% compared with peers from Experimental-1 groups. By the number of eosinophils (Experimental-2 group), characterizing the stress state of piglets, their decrease was observed within 10–12 days, not more than 5 days — in animals from Experimental-1 group and up to 3 days — from control

scholarly journals NATURAL RESISTANCE AND DEVELOPMENT OF EGG-TYPE REPAIR YOUNG CHICKS

2021 ◽  
Vol 246 (2) ◽  
pp. 132-136
Author(s):  
А.А. Menkova ◽  
◽  
V.N. Shilov ◽  
Е.М. Tsygankov ◽  
◽  
...  
Keyword(s):  
Blood Serum ◽  
Phagocytic Activity ◽  
Lysozyme Activity ◽  
Natural Resistance ◽  
Poultry Farm ◽  
Immune Protection ◽  
Poultry House ◽  
Blood Neutrophils ◽  
And Control ◽  
Experimental Group

Blood and lymph make up the circulatory link of the bird's immune system. It is necessary to note the humoral factor of immune protection-lysozyme. The purpose of scientific research is to study the level of natural resistance and development of egg-type chickens after aerosol application of the disinfectant Argodez. Research and production experiments were conducted in the conditions of the poultry farm "snow", Bryansk region, p. Voucher. Aerosol disinfection was performed in the poultry house before settling in with day-old chickens. Test shop were treated once Arcadetm of 0.01%, the rate of 2 ml/m3, and control Desalina - f - 5 ml/m3., with the generator cold fog IGEBA -UNIPRO-5. At the age of 24 hours, two groups of egg - type chickens, the Lohmann-brown cross, were formed using the method of analogous groups. Blood was taken from the underwing vein and by decapitation, before feeding, at the daily, 30-day, 60-day age. Bactericidal, lysozyme, and phagocytic activity of blood serum was determined according to generally accepted methods. Control weighing of chickens of both groups was performed on days 30 and 60 of the study. A significant increase in phagocytic activity of blood neutrophils was found in the experimental group of chickens on the 30th-21.40 % and 60th day of research-25.40 %, as well as a tendency to increase the bactericidal activity of blood serum by 1.90 % and 7.90 % and the lysozyme activity of blood serum by 8.46 % and 9.17 %. It was also found to increase safety by age periods. The highest safety was observed at the age of 1-30 days and was 99.50 %, then 30-60 – 99.10 %.

scholarly journals Nonspecific reactivity of the rabbits organism when exposed to cysticercosis

2019 ◽  
Vol 21 (94) ◽  
pp. 132-135
Author(s):  
Y. V. Duda
Keyword(s):  
Blood Serum ◽  
Bactericidal Activity ◽  
Immune Complexes ◽  
Research Group ◽  
Phagocytic Activity ◽  
Lysozyme Activity ◽  
Circulating Immune Complexes ◽  
Control Group ◽  
E Coli ◽  
Test Culture

One of the actual rabbits breeding problem is the reduction of their resistance, which is caused by the spread of individual invasive diseases, especially cysticercosis, which is caused by the larval Cysticercus pisiformis stage of the mature cestode Taenia pisiformis. The study was conducted on 38 male rabbits age 3–4 months, weighing 3.5–4.0 kg of the Californian breed, selected by analogy. Animal were separated into two groups: healthy animals (control group) and sick animals (research group). After blood collection, slaughter was conducted and the presence of cysticercus cysts was visually determined in the organisms of the rabbits. Control animals received a balanced standard granular feed and water without limit; research group in addition to the standard granulated feed with water received flaccid hay. The animals were kept in mesh single-tier cages in the room, according to the current veterinary and sanitary standards. The definition of phagocytic activity of neutrophils was carried out with the addition of standardized to 2500000000/ml suspension of daily culture of E. coli 055K59№3912/41. The bactericidal activity of blood serum was determined by the method Smirnova A.V. and Kuzmina T.A. in relation to the E. coli microbial test-culture 055K59№3912/41. The serum lysozyme activity was determined by the Nephelometric method using the Dorofachuk V.G. method to the microbial test culture Micrococcus luteus ATSS9341. Circulating immune complexes were determined using polyethylene glycol in borate buffer (pH 8.4). It was found that in blood of sick animals phagocytic activity is lower than in blood of healthy ones (respectively, 41.82 ± 1.51% versus 47.38 ± 1.10%, P < 0.01). The main cells involved in phagocytosis are leukocytes, in particular neutrophils and eosinophils. A low indicator of phagocytic activity shows depressed phagocytosis in the organism of animals suffering from cysticercosis of rabbits. The phagocytic number in the blood of rabbits of the experimental group was significantly lower by 0.51 units (P < 0.05) as compared to the control group and correlated with the index of phagocytic activity. An important element of immunity are indicators of bactericidal and lysozyme activity of blood serum. Low bactericidal activity of serum by 12.88% (P < 0.01) and lysozyme activity in rabbits with Cysticercus pisiformis also indicates a weakening of the factors of nonspecific natural resistance of the organism. Analyzing the level of circulating immune complexes, we found a high level of medium (9.14 ± 0.40 vs 5.58 ± 0.50) and small (9.21 ± 1.35 vs 4.64 ± 0.68) CIC for cysticercosis, respectively, 1.64 (P < 0.01) and 1.98 times (P < 0.001) against the control. This indicates the inhibition of the immunobiological activity in the organism of rabbits as a result of the combination of specific antibodies with the products of the exchange of helminths.

scholarly journals Adaptation of the status of non-specific resistance of the ducks organism in stress conditions inclusion in the ration of probiotical additives

2018 ◽  
Vol 20 (87) ◽  
pp. 32-37 ◽  
Author(s):  
V.G. Stoyanovskyy ◽  
A.О. Krogh ◽  
I.A. Kolomiіets
Keyword(s):  
Body Weight ◽  
Blood Serum ◽  
Bactericidal Activity ◽  
Immune Complexes ◽  
Specific Resistance ◽  
Lysozyme Activity ◽  
The Body ◽  
Circulating Immune Complexes ◽  
Control Group ◽  
Technological Stress

The article deals with the question of adaptation of the ducks organism during industrial cultivation for action of stress. The complex of successive stage reactions, caused by the functioning of stress-implementing systems, arise in the body of the poultry in response to the influence of destabilizing factors and aimed at neutralizing these factors, preservation of homeostasis. Increasing the influence of technological stress factors leads to a decrease in the immune status of the duck organism. The study of the effectiveness of incorporating into the diet ducks harmless feed additives, which contributes to the normalization of the course of adaptive-compensatory reactions in their body during the critical periods of postnatal ontogenesis and can serve as anti-stress prevention in conditions of industrial growth of this species of poultry remains relevant. The purpose of the work is to find out the implementation of an adaptation syndrome in the system of indices of non-specific resistance of the body of ducks when it is included in the diet of the biologically active feed supplement «Primix Bionorm K» and supplements «Biovir». The experiment was conducted on clinically healthy young ducks of the Pekin breed of egg production line. In the 270-day age, all three groups of ducks were modeled experimental technological stress in the form of prolonged transport. From 240 to 270 days of age, ducks additionally fed the additive «Primix Bionorm K» and was pouring with water an additive «Biovir». The material for research was blood, which was taken until morning feeding after slaughter on 240 days of life (to stress), 270 days of life (stage of anxiety), at 273 and 285 days (stages of resistance). Adaptation of the state of non-specific resistance of the duck of the control group to the control group under conditions of stress in the anxiety stage is characterized by an increase of 17.3% (Р < 0.05) of the value of the bactericidal activity of the blood serum, a decrease of 8.5% of the value of lysozyme activity of the blood serum, by 9.3% of phagocytic activity against the background of growth on 8.7% of the number of circulating immune complexes compared to 240-day-old poultry. At the stage of resistance there is a decrease in the amount of blood serum bactericidal activity by 17.3% (Р < 0.05), an increase in the activity of lysozyme in blood serum by 8.5%, and the number of immune complexes by 20.7% (Р < 0.05), with the stabilization of the studied parameters at the later stages of the development of a stress reaction. In these periods, a decrease in the body weight of control group ducks was set at 5.7 – 6.8%. Feeding of the additive «Primix Bionorm K» during the period of the implementation of the stress syndrome has a positive effect on the indices of the cellular and humoral level of nonspecific resistance in the form of an increase in the amount of bactericidal activity of the serum on 38.2% (P < 0.05), an increase in the activity of phagocytosis by 15.1% (P < 0.05), phagocytic index – by 36.1% (P < 0.05) with a decrease in the number of circulating immune complexes by 15.5%. The presentation of the additive «Biovir» causes an increase in the level of bactericidal and lysozyme activity of the blood serum on 47.3% (P < 0.01) and 18.7% (P < 0.05). The use of additives can reduce the negative effect of transport stress in the duck body, increase nutrient uptake, as indicated by an increase in the body weight of experimental birds in the average by 7.1–10.5% (P < 0.05) during the development of the adaptive syndrome.

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

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