scholarly journals Stress state and immunological status of young pigs

Author(s):  
M. V. Chornyi

The paper presents the results of studies on the effect of regrouping of piglets at different ages on the resistance of their organisms, immunological status, productive qualities and safety of young pigs. The work was performed at “Stas” LLC on large white breed pigs and their crossbreeds. For the experiment, three groups of piglets were formed from suckling sows — analogues. In the experiment 60 animals from birth up to two months of age were used, 20 animals in each experimental group. The control group of piglets was raised from birth up to 60 days of age in nests, and then they were moved to the rearing workshop; Experimental 1 group was kept up to 10 days old in nests, and then a one-time rearrangement was performed according to live weight. Piglets from experimental group 2 were regrouped according to live weight at 5, 10, 15, 21, 30 days of age. To assess the natural resistance of piglets due to the above groups, hematological, biochemical (total protein, protein fractions) methods, immunological (immunoglobulins of classes IgA, IgM, IgG), and natural resistance (bactericidal activity of blood serum) were used, serum lysozyme activity (LASK), phagocytic neutrophil activity (FAN), phagocytic index (FI), ethological, zootechnical, mathematical. To assess the natural resistance of piglets the following research methods were used: generally accepted zoo veterinary methods (live weight, morbidity, safety), hygienic (microclimate conditions, sanitary regime), hematological (morphological blood composition), biochemical (total protein, protein fractions), immunological (immunoglobulins of classes IgA, IgM, IgG), natural resistance (bactericidal activity of blood serum), ethological and mathematical methods. Results of work. It was found that when growing piglets, nesting, without moving, caused their growth and development without any noticeable physiological disturbances, both from the blood and ethology. In animals (Experimental-1 groups) which underwent a single regrouping in a 10 day reward, their lag in live weight by 12.65% was recorded, compared with the control, with two and three-time movement (Experimental-2) — by 16.10%. Their SSPs were 28% less and 14.7% lower than in the control piglets. Patients with symptoms of diarrhea were identified in the control: in 3–4 daily reimbursement — 1%, in Experimental-1 — 5%, Experimental-2 — 10–15%. The resistance of young animals to gastrointestinal diseases according to the Melenberg coefficient in the Experimental-2 group was 6.13–7.48, in control group it was 0.34, and the safety did not exceed 80.2%. According to the level of immune status, animals from Experimental-2 group were inferior: by BASK — by 25.15% (28 days of age), by LASK — by 7.56%, by FAN — by 10.7% compared with peers from Experimental-1 groups. By the number of eosinophils (Experimental-2 group), characterizing the stress state of piglets, their decrease was observed within 10–12 days, not more than 5 days — in animals from Experimental-1 group and up to 3 days — from control

2021 ◽  
Vol 291 ◽  
pp. 02007
Author(s):  
Elena Ulrikh ◽  
Olga Babich ◽  
Stanislav Sukhikh

During the study, it was found that an increase in the dose of sweet yellow clover extract from 0.5 to 2.5 mg/kg of live weight per day contributed to an increase in the number of: hemoglobin by 1.83 g/l (1.79%), leukocytes by 0.14 thousand 109/l (2.34%), total protein in blood serum of sheep by 0.43 g/l (0.7%), glucose in blood of sheep by 0.18 mmol/l (4.19%), calcium in blood of sheep by 0.14 mmol/l (5.32%), phosphorus in blood of sheep by only 0.08 mg/100 ml (1.6%), contributed to an increase in the live weight of sheep by 220 g (2.18%). In the control group, two sheep out of six got bronchitis. The percentage of sheep with bronchitis was 33.33%. After feed to the sheep different doses of sweet yellow clover extract, the sheep in groups I and II of the experimental groups had one sheep each (16.67%), while in groups III, IV and V there were no sheep with bronchitis. Thus, increasing the sweet yellow clover dosage in sheep’ diet reinforced their immunity. In the control group and in the first experimental group, one sheep out of six came down with dyspepsia. The percentage of sheep with dyspepsia was 16.67%. After feed to the sheep doses of sweet yellow clover extract, there were no dyspeptic diseases in sheep.


Author(s):  
S. Grikshas ◽  
N. Kulmakova ◽  
K. Spitsyna ◽  
A. Dar’in ◽  
T. Mittelshtein

Mycotoxins have been formed in feed are secondary metabolites of fungi and are quite stable substances that have teratogenic, mutagenic and carcinogenic effects. An effective way to combat mycotoxins in feed is the use of feed additives that adsorb toxins, prevent their absorption in the gastrointestinal tract of the animal and are excreted from the body. The infl uence of coconut enterosorbent Shelltic Es on fattening and meat qualities of young pigs has been studied. It has been found in the process of fattening that the highest feed digestibility was in pigs of the experimental group, in the diet of which enterosorbent has been added. The results of studies of the chemical composition and technological properties of pork have been provided. The positive eff ect of enterosorbent on precocity, absolute average daily gain of live weight and reduction of feed expenditures per 1 kg of gain has been revealed. In pigs from the experimental group the average thickness of the fat was higher and the area of the “muscle eye” was lower compared with animals of the control group, which indicates that higher rates of carcass yield have been obtained due to faster accumulation of fat tissue. The weight of internal organs of pigs indicates the intensity of metabolic processes in the body. In experimental animals the weight of the lungs was 0,1 kg lower, and the liver and heart were higher by 0,13 and 0,01 kg, respectively. Enterosorbent had no effect on the content of vitamins in the liver of pigs of the compared groups. The content of impurities of organochlorine toxicants and toxic elements in the meat and liver of animals of the experimental group was lower than that of control analogues. Therefore, the use of enterosorbent Shelltic Es promotes more active excretion of them from the body.


Author(s):  
A. S. Ivanova ◽  
N. V. Dunaeva

Increasing the production of pork meat requires careful work not only in terms of breeding, but also in the organization of complete feeding of animals, the correct selection of feed and feed additives containing the necessary nutrients. The purpose of the work was to analyze the use of premix in feeding young pigs on fattening. Two groups of fattening young pigs (Large White×Landrace) have been selected for the researches using the method of analogous groups, taking into account the breed, age, and live weight per 20 heads in each group with a live weight of 35 kg. Pigs of the control group have received the main economic diet, and animals of the experimental group have received an additional premix Khutorok at the rate of 10 g of premix per 1 kg of feed. The results have shown that the best age to reach 100 kg was in the experimental group of pigs – 215,8 days, which received premix with feed that characterizes their higher precocity by 36,3 days (P < 0,001) than in the control group of animals. The use of this premix had a positive impact on the livability of young animals, in the experimental group it was by 9,3 abs.% more than in the control group of animals. Thus, the best fattening traits have been possessed by young pigl of the experimental group have been received the premix Khutorok in their diet at the rate of 10 g of premix per 1 kg of feed. The obtained data indicate the feasibility of using the premix Khutorok in the feeding pigs for fattening.


Author(s):  
L. Bondarenko

The immune system is central to ensuring the consistency of the body's homeostasis. The state of the body's natural resistance is determined by a set of non-specific protective mechanisms. Lymphocytes and phagocytes are actively involved in maintaining immunity. Lymphocytes recognize the antigens of pathogenic microorganisms, and phagocytes absorb and destroy the pathogens themselves. During the weaning of piglets from sows there is a decrease in the protective forces of their body. During this period, the natural resistance of the piglets is reduced due to the stressful situation caused by changing conditions of confinement, the transition to full feed and lack of sows. The immune system of weaning pigs is relatively weak, so when exposed to environmental and technological stressors, they become susceptible to various diseases. The use of probiotic drugs stimulates the activity of the immune system, prevents stress and immunodeficiency. One of these probiotics is the probiotic of domestic production Protecto-active. It w observed the the influence of the probiotic Protecto-active on the indices of nonspecific resistance of the young pigs organism to the growth. An increase in bactericidal activity of blood serum by 12.10% (P <0.05) and lysozyme activity of blood in the piglets of the experimental group was increased by 3.71% compared to control, which indicates the activation of the body's defenses and the increase in adaptive capacity. An important step in the study of the influence of the probiotic Protekto-active on the state of the immune system is to determine the phagocytic activity of neutrophils, phagocytic index and phagocytic number. In the experimental group of piglets that were fed the probiotic Protecto-active, we found an increase in leukocyte phagocytic activity by 9.0% (P <0.001), a phagocytic index by 51.7% (P<0.001) and a phagocytic number by 24.8% ( P <0.01) compared with the control group. Thus, using a probiotic Protecto-active, all indicators of phagocytosis increase: the number of phagocytes increases, their ability to capture microorganisms and increases their digestive capacity, it increases the bacterial and lysozyme activity of blood serum, which is positively reflected in the immunobiosity. Key words: probiotic, phagocytosis, phagocytic index, phagocytic number, phagocytic activity of leukocytes, cellular immunity, piglets


Author(s):  
S. I. Nikolaev ◽  
O. V. Korneeva ◽  
V. V. Shkalenko ◽  
A. K. Karapetyan ◽  
L. A. Syuliev

The experiment has been carried out on a crossbred stock of young pigs in the period 2015–2017 under the conditions of JSC CHC “Krasnodonskoe” in the Ilovlinsky district in the Volgograd region. The purpose of the research was to study the effectiveness of the effect of the anti-stress drug Feed-Food Magic Antistress Mix in intensive pig rearing on the productive traits and quality of the products obtained, as well as the estimated economic indicators. In order to conduct a scientific and economic experiment at the age of 60 days young pigs were divided into 2 experimental groups (control and experimental) according to the principle of pair analogs. Each group contained 25 heads. The difference between the control and experimental groups was that the animals in the control group have received the main diet, and the experimental group has received the anti-stress drug Feed-Food Magic Antistress Mix in addition to the main diet. In the experimental group of pigs when this drug was administered in the age 180 days the live weight parameter was higher than in the control group by 1,55 kg. Clinical indicators of young pigs were within the physiological norm. The pre-slaughter weight in the experimental group has increased by 4,86 % compared to the control group. Due to the use of an anti-stress drug the slaughter weight of animals in the experimental group has increased by 6,69 %. In comparison with the control group the slaughter yield in the experimental group has increased by 1,18 %, in which this indicator was at the level of 67,62 %. The morphological composition of carcasses in animals of the experimental group was also improved. Meat yield has increased by 0,95 %. The yield of fat and bones has decreased by 0,59 and 0,36 %. The weight of internal organs was also superior in the experimental group of pigs. Due to the use of the anti-stress drug the level of profitability in the experimental group of animals has increased by 11,69 %.


2021 ◽  
Vol 6 (1) ◽  
pp. 64-70
Author(s):  
Andrei Frolkin ◽  
Haidar Valitov ◽  
Aleksandr Varakin ◽  
Valentina Kornilova

The purpose of the research is to increase the effectiveness of the supplement Reasil on the growth of milk-fed calves. For the scientific and economic experience, three groups of calves were formed (control, 1 and 2 experi-enced). Groups of animals of 10 heads were formed according to the principle of analogues. The indicators of live weight, growth and blood of calves were studied after Reasil use in a diet: Reasil HumicVet as a liquid form, and Reasil Humic Health – reduced to powder. In the experiment, animals of a black-and-white breed were used. The Reasil feeding in the diet contributed to an increase in the live weight of milk-fed calves in the 1-st and the 2-nd experimental groups at two months of age by 5.65 and 5.48 kg (or by 7.4 and 7.2%), respectively, compared to the indicator of the control group analogues. The average daily growth of calves of the experimental groups exceeded this indicator of control animals by 96 and 82 g, respectively. The blood of calves of the 1st and 2nd experimental groups, showed that hematoglobin was higher by 15.7 and 11.4%, red blood cells – by 16.5 and 15.1%, and the alkaline reserve – by 5.2%, compared with blood of calves from the control group, which indicates the activation of metabolic processes in the body. The total protein amount in the blood serum of animals from the experimental groups increased by 8.4 and 5.9% respectively, compared to the tests of calves from the control group. The albu-min content of animals of the 1st experimental group tested was higher by 5.3%; from the 2nd experimental group there was no significant difference compared to the control. The number of gamma-globulins in the blood of ani-mals of the experimental groups increased, which indicates an increase in defense reaction of animals. The con-tent of calcium in the blood serum of calves from the experimental groups was higher by 8.3 and 5.9%, phosphorus – by 4.8 and 2.4%, which indicates a more effective use of these mineral elements.


Author(s):  
I.I. Okulova ◽  
◽  
I.A. Domsky ◽  
Yu.A. Berezina ◽  
Z.N. Beltyukova ◽  
...  

The use of «Arkusit» at a dose of 20 μg / kg of body weight indicates a beneficial effect on the factors of nonspecific resistance of the silver-black fox. The concentration of alkaline phosphatase in the blood serum in the experimental group decreased by 1.8 times (P <0.001), the ALT index - by 1.2 (P <0.05). The concentration of glucose in the experimental group increased 2 times (P <0.05) compared with the control group. In animals of the experimental group, the lysozyme activity of blood serum increased 1.3 times (P <0.05), the OPR reaction and the phagocytic index - 1.4 times (P <0.05), the bactericidal activity of blood serum - 1.8 times (P <0.05). «Arcusit» stimulates the synthesis of gamma globulins, increases the opsonophagocytic, bactericidal activity of blood serum. Thus, the analysis of experimental data indicates that the drug «Arcusit» has a pronounced immunostimulating effect, providing the activation of factors of nonspecific resistance of the body of the silver-black fox.


Author(s):  
L. Gamko ◽  
M. Badyrkhanov

The purpose of the researches was to study the influence of different doses of smectic kizelgur and calf skim milk replacer in the recipes of compound feed for young pigs under the conditions of industrial pork production technology. The experimental part of the work has been performed under the conditions of the pig complex of LLC “BMPK” in the Karachevsky area in the Bryansk region. The research materials were compound feed for young pigs on fattening in the inclusion of different doses of smectic kizelgur. The infl uence of feeding compound feed with different doses of smectic kizelgur and calf skim milk replacer to young pigs on productivity, digestibility of nutrients and use of nitrogen, morphological and biochemical parameters of blood, fattening and meat traits of young pigs has been studied. Effective recipes for feeding compound feeds to young pigs prepared with the inclusion of different doses of smectic kizelgur and calf skim milk replacer have been identified. The data have been obtained from the first experiment of young pigs when them fed compound feed with different doses of smectic kizelgur; it has been followed that at the end of fattening the biggest live weight of gilts had in the 4th experimental group fed compound feed, which included 3 % smectic kizelgur. The influence of the additive on changes in live weight and daily gains when adding smectic kizelgur to compound feed in doses of 1,5 and 2,0 % was less, but the trend to increase these indicators over the period of fattening has remained. In the second experiment young pigs have been fed by compound feed, which included different doses of smectic kizelgur and calf skim milk replacer the average daily gain in live weight was higher in the 3rd experimental group, where they fed compound feed with the addition of 2,5 % smectic kizelgur and 2,5 % calf skim milk replacer by 2,2 %, than in the control group. The highest efficiency has been also obtained in the 3rd experimental group, where the monetary revenue has been received by 2160 rubles more in comparison with the control group of pigs.


2021 ◽  
Vol 32 ◽  
pp. 04004
Author(s):  
Marina Slozhenkina ◽  
Ivan Gorlov ◽  
Alexei Miroshnik ◽  
Dmitriy Nikolaev

The article presents an analysis of the use of antibiotic therapy in pig breeding and offered an alternative to them in the form of prebiotic supplements. Studies were conducted on the effect of probiotic drugs on the body of large white pigs in the farm-breeding plant Named after Lenin of Surovikinsky District of Volgograd Region and lasted until 180 days of age. For the experiment, 2 groups of Large White piglets of 2 months of age were formed. Each experimental group consisted of 15 pigs. Animals of the control group received standart farm animal diet (SD), analogs of the first experimental group SD + mixture of dietary supplements “LactuVet-1” and “Chlorelact” at a dosage of 0.2 mg / kg of live weight each. Deep studies were conducted on the effect of probiotic supplements to live weight gain, natural resistance, immunoglobulin reactivity, and slaughter indicators of piglets. Superiority of pigs from the experimental group in almost all the studied indicators over the peers of the control group was established.


Author(s):  
V. V. Bondarenko

The research was conducted on two groups–analogues of young pigs of large white breed with 10 pigs each. Weaned piglets at the age of 28 days were fed with the protein–vitamin mineral supplement «Minaktyvit» – starter in the amount of 25% of grain feed (33 days), while young pigs in growing were given the protein–vitamin mineral supplement «Minaktyvit» – grower in the amount of 15% (50 days) and those in fattening the protein–vitamin mineral supplement «Minaktyvit» – finisher in the amount of 10% (62 days). The control group received protein–vitamin mineral supplement. At the end of growing with the live weight of 100 – 110 kg a control slaughter was carried out and samples of stomach, small and large intestines for laboratory tests were picked out. Studies have shown that feeding of young pigs with the protein–vitamin mineral supplement «Minaktyvit» increases the average daily gains by 95 g or 15.68%, while their level is 701 g in the experimental group of animals and 606 g in the control one. The protein–vitamin mineral supplement «Minaktyvit» incredibly affected the morphological parameters of the stomach in the experimental group of pigs. However, the thickening of the walls by 4.3%, 5% and 10.9% respectively is observed in cardiac, fundic and pyloric areas of the experimental group, compared to the control one. The thickening of the walls in stomach areas under the influence of feed factor is associated with increasing of the mucosa thickness. Mucosa increased by 0.1 mm in the cardiac area, 0.36 mm in fundic and 0.53 mm in the pyloric one. The change in the structure of the investigated jejunum is observed while consuming the protein–vitamin mineral supplement «Minaktyvit» in the diet. The wall thickness increased by 17.57% (P < 0.05), including the thickening of mucosa by 16.7% and that of serous–muscular shell by 18.8%. No significant difference in the structure of the colon in the experimental group of animals was determined.


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