Comparison of Two Conjunctival Incision Techniques in Strabismus Operations: Analysis of the Patient Population in 2008, 2010 – 2014

Author(s):  
Svenja Froelich ◽  
Arne Viestenz ◽  
Timm Bredehorn-Mayr

Abstract Background Until 2010, the Halle university hospital used the limbal approach in strabismus operations to open the conjunctiva, as first described by Harms in 1949. In 2010, this was changed the to a modified radial incision technique, as inspired by the fornix incision of Harms and the “minimally invasive strabismus surgery” (MISS) technique of D. S. Mojon. The indication is the reduction in complications and protection of the conjunctiva. Methods A retrospective analysis was performed of cases between 2008 and March 2014 was performed, including a total of 258 patients. 109 patients were treated with the limbal approach and 149 patients with the radial cut. The following aspects were included for comparison: the medium-term control of the squint angle after three months, intra- and postoperative number of complications, duration of the operations. A survey collected the reasons for not taking part in follow-up checks and the alignment of these patients. To compare binary variables, the chi-square-test was used and to compare average terms the unpaired t test, with a level of significance of 0.05%. Results The results of the postoperative square angles were comparable to both each other as to the literature. The number of complications was kept low in both techniques. The duration of the operations under the radial incision technique was clearly higher. However, throughout the observed years the duration of operations turned out to have decreased. The reasons for not taking part in controls were diverse and the alignment of these patients was high, regardless of the incision technique. Conclusions The limbal approach was a well-proven method to open the conjunctiva. After changing to the radial incision technique, there was never a negative influence on the results of the surgeries or the rate of complications. The duration of the operations was extended. Superiority of the new technique was not shown. It could however be an alternative, as it spares the conjunctiva and permits glaucoma operations.

2020 ◽  
Vol 5 (5) ◽  
pp. 01-04
Author(s):  
Stella Onwubiko

Background: Glaucoma is an emerging vision-threatening disease requiring a life-long management protocol with regular surveillance. Aim: To explore the factors associated with and reasons for loss to follow-up among glaucoma patients. Methods: All adult glaucoma patients who attended Bridget medical Centre (BMC) Eye hospital, Enugu during a two-year period (2016 – 2018) were identified via the medical records. Those who had missed an appointment by at least 12 months were reached via their cellular phones to ascertain their reasons. Information on their socio-demographic and clinical characteristics was retrieved from their records. Data was analyzed using SPSS version 21. Chi-square test was done to identify the factors associated with loss to follow-up. The level of significance was at p< 0.05. Results: A total of 113 patients had glaucoma. They were mainly males, 67(59.3%), retirees with a mean age of 62.0±2SD years. Ninety-four (83.2%) participants were lost to follow-up. The main reasons were forgetfulness, 33(41.2%), and have not noticed any problem in vision, 20(25.0%). Male gender, advanced age, tertiary education, retiree, normal visual acuity, moderate/advanced stage, IOP of less than 21mmHg, more than 5 years of diagnosis and using more than one medication were associated with loss to follow-up. However, only Retiree and IOP of less than 21mmHg were statistically significant. Conclusion: The findings from this study emphasized the need for continual glaucoma education and appointment reminder, especially to Retirees with normal intraocular pressure.


2019 ◽  
Vol 7 (1) ◽  
pp. 1-6
Author(s):  
Ahmed Fathy Arafa ◽  
Nawras Maher Mostafa ◽  
Shady Ahmed Moussa

Many studies have explained temporomandibular joint (TMJ) sounds in children are frequent with TMJ disorder. In addition to multiple divergent findings are designed to evaluate the relationship between bruxism and TMJ disorder in children. Aim: study was designed and conducted to assess the possible relationship between bruxism and joint sounds in schoolchildren. Subjects and Methods: The sample comprised 60 schoolchildren participants between 6 to 10 years of age, of whom 30 children with bruxism as study group G1 and another 30 without bruxism as a control group G2 who were scheduled and randomly selected for treatment at (Outpatient Dental Clinics, Zagazig University Hospital). Examiner performed assessment who was blinded allocation of the groups. Assessment involved of (manual palpation, lateral and dorsal extra-auricular auscultation of TMJ by stethoscope for detecting of joint sounds, differentiating between joint sounds as a click/pop or crepitation) Three readings were performed on each participant. Collected data were checked, entered and statistically analyzed to test different variables by chi-square test with the level of significance (p< 0.05). Results: There were statistically significant association between joint sounds with regarding to bruxism and age, which showed the higher prevalence rates of joint sounds were found in children aged eight to ten years in comparison to those aged sex and seven years. However, there were statistically insignificant association between joints sounds and type in relation to gender. Conclusion: The bruxism in children may be associated with the symptoms of joint sounds with significant association regarding to age. Keywords: Bruxism; Temporomandibular Joint; Child; bruxism; TMJ sound


Author(s):  
Y. Cissoko ◽  
L. N. Sidibé ◽  
J. P. Dembele ◽  
A. A. Oumar ◽  
A. Traoré ◽  
...  

Accidental exposure to blood (AEB) constitutes a risk of transmission of blood-borne viruses including HIV, hepatitis B and hepatitis C virus especially amongst health workers. This study aims to describe accidental exposure to blood and post exposure management five years after it begin at the Hospital of Gao, since 2012 there is insurrection in this area making difficult to maintain health care system. This study will help to identify gaps to fill in order to improve the prevention of blood borne pathogen infection in this hospital. All cases of AEB declared at the Hospital from January 1st 2007 to December 31, 2011 have been enrolled. The sociodemographic profile of victims, the circumstances of the accident, the post exposure management and the follow up of subject have been registered. Data were entered and analyzed with the SPSS software. Chi square test was used with the level of significance p<0.05. During the 60 months of the study, an average of 124 workers were employed at the Hospital of Gao and 15 cases of accidental blood exposure were declared equal to an incidence density of 4.2 cases per 100 persons per year. Males were the most affected (60%). Nurses and lab technicians represent the majority of victims (53.3%). The most frequent type of accident was the injury by cannula needle sticks during intravenous injections (73.3%). Most of the cases received High Activity Antiretroviral Therapy (HAART) within a mean delay of 25 Hours from the accident, and the regiment (AZT/3TC/LPV/r) is predominantly used. HIV serology was done in 53.3% of subjects and revealed 1 positive case. Initial blood tests in all victims were normal. The HAART observance was worst among medical doctors (p < 0.001). No contaminations by HIV were detected after 6 months of follow up. The frequency of declared accidental exposures to blood at the Hospital of Gao is low. The post exposure management is facing a problem of observance of the treatment whenever it shows efficacy in all cases.


2021 ◽  
Vol 108 (Supplement_3) ◽  
Author(s):  
G Martínez Izquierdo ◽  
A R Arnaiz Pérez ◽  
E Escolano Fernández ◽  
M Merayo Álvarez ◽  
B Carrasco Aguilera ◽  
...  

Abstract INTRODUCTION Renal cell carcinoma (RCC) represents 3% of overall malignant neoplasms in adults. However, its aetiology has not been clearly established. Although surgery represents the cornerstone in treatment, recurrence postoperative rates are around 20-30%, what implies prognostic factors search must be mandatory in order to help to plan de follow-up and the different adjuvant therapy possibilities available in case they were necessary. MATERIAL AND METHODS A retrospective observational study was carried out in 110 patients who underwent radical nephrectomy between 2004 and 2018, with the aim of identifying possible prognostic factors of recurrence of RCC after these surgeries. Preoperative data (epidemiological, comorbidities and laboratory tests), surgical, pathological and variables related to follow-up were taken into account. A univariate and multivariate analysis were performed, using chi-square test and logistic regression, respectively. RESULTS The median follow-up time was 53.5 months (SD = 35.8), time in which 19 patients had a recurrence of RCC after radical nephrectomy (17.2%). Histopathological items such as the surgical piece size, the nodal and microvascular invasion, the renal sinus invasion and the presence of necrosis in the surgical piece were associated with RCC recurrence in the univariate analysis, while only the presence of necrosis in the surgical piece showed a significant result in the multivariate analysis (p = 0.004). CONCLUSIONS Histopathological analysis, highlighting the presence of necrosis in the histological sample, was proved to be the main risk factor of RCC recurrence.


Author(s):  
Olayinka Stephen Ilesanmi ◽  
Priscilla Onaopemipo Akosile ◽  
Aanuoluwapo Adeyimika Afolabi ◽  
Victor Okoliko Ukwenya

Abstract Background This study aimed to assess the level of trust in the COVID-19 risk communication efforts in Nigeria. Methods We conducted a descriptive cross-sectional study among community members aged 15 years and above in Ondo state in October, 2020. Data were collected using an interviewer-administered questionnaire. Data were analyzed using SPSS version 22. Descriptive statistics were summarized using frequencies. Trust was ranked from “1” implying “Low level of trust” to “7” denoting “High level of trust”. We conducted bivariate Chi-square test on respondents’ level of trust in the Nigeria Centre for Disease Control (NCDC) and socio-demographic characteristics. The level of significance was set at p<0.05. Results Among the 691 respondents, 244 (35.3%) were aged 21 to 29 years, and 304 (51.4%) used the NCDC to obtain COVID-19 knowledge. Overall, 205 (41.8%) had high level of trust in the NCDC. Furthermore, 51 (51.5%) individuals aged 30-39 years had high level of trust in the NCDC (ᵡ2=17.455, p= 0.001). Also, 114 (48.5%) persons who lived with children below 18 years had high level of trust in the NCDC (ᵡ2= 8.266, p= 0.004). Conclusion Policy makers should prioritize the involvement of young and educated persons in COVID-19 risk communication strategies.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Stefano Martina ◽  
Alessandra Amato ◽  
Paolo Faccioni ◽  
Alfredo Iandolo ◽  
Massimo Amato ◽  
...  

Abstract Background The present study aimed to investigate the patients’ perception of the dental practice during the COVID-19 outbreak, and whether the pandemic will affect the attendance of orthodontic patients at the dental practice. An online questionnaire, including the Patient Health Questionnaire-4 (PHQ-4), was submitted to Italian dental patients with items about their perceived risks when going to the dentist, concerns about continuing orthodontic treatment, and the onset of temporomandibular disorders (TMD). Data were analyzed with a chi-square test and logistic regression analysis. The level of significance was set at P < 0.05. Results A total of 1566 subjects completed the survey, including 486 who were under orthodontic treatment or who had a child in orthodontic treatment. A total of 866 participants (55.3%) thought the risk of contracting the COVID-19 infection was higher in a dental practice; this perception was associated with gender (women more than man), age (over 60 years old) and high levels of distress (P<0.001). However, 894 patients (57.1%) felt comfortable going back to the dentist. Most of the orthodontic patients (84%) would continue their treatment. After the lockdown, there was a slight increase in the frequency of TMD pain (356 versus 334). Conclusions Most of the participants believed that the dental practice is a place at greater risk of contracting COVID-19, even if they continue to go to the dentist. Gender, age, and the level of distress were associated with the increase in the fear of going to the dentist due to COVID-19. Because of the pandemic, 16% of patients undergoing orthodontic treatment would not return to the dental practice to continue their orthodontic treatment after the lockdown. The prevalence of TMD pain in the population increased due to the pandemic.


BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mei-Zhen Dai ◽  
Yi Qiu ◽  
Xing-Hong Di ◽  
Wei-Wu Shi ◽  
Hui-Hui Xu

Abstract Background Human papillomavirus (HPV) type 16 accounts for a larger share of cervical cancer and has been a major health problem worldwide for decades. The progression of initial infection to cervical cancer has been linked to viral sequence properties; however, the role of HPV16 variants in the risk of cervical carcinogenesis, especially with longitudinal follow-up, is not fully understood in China. Methods We aimed to investigate the genetic variability of HPV16 E6 and E7 oncogenes in isolates from cervical exfoliated cells. Between December 2012 and December 2014, a total of 310 single HPV16-positive samples were selected from women living in the Taizhou area, China. Sequences of all E6 and E7 oncogenes were analysed by PCR-sequencing assay. Detailed sequence comparison, genetic heterogeneity analyses and maximum-likelihood phylogenetic tree construction were performed with BioEdit Sequence Alignment Editor and MEGA X software. Data for cytology tests and histological diagnoses were obtained from our Taizhou Area Study with longitudinal follow-up for at least 5 years. The relationship between HPV16 variants and cervical carcinogenesis risk was analysed by the chi-square test or Fisher’s exact test. Results In this study, we obtained 64 distinct variation patterns with the accession GenBank numbers MT681266-MT681329. Phylogenetic analysis revealed that 98.3% of HPV16 variants belong to lineage A, in which the A4 (Asian) sublineage was dominant (64.8%), followed by A2 (12.1%), A1 (11.4%), and A3 (10.0%). The A4 (Asian) sublineage had a higher risk of CIN2+ than the A1–3 (European) sublineages (OR = 2.69, 95% CI = 1.04–6.97, P < 0.05). Furthermore, nucleotide variation in HPV16 E6 T178G is associated with the development of cervical cancer. Conclusion These data could provide novel insights into the role of HPV16 variants in cervical carcinogenesis risk in China.


2021 ◽  
Vol 2 (01) ◽  
pp. 50-60
Author(s):  
Yam Prasad Pandeya

Parental factors play vital role in academic attainment of their offspring. Motivation and counseling stimulate someone to take a desired course of action. This paper attempts to explore the perception of children towards their patents in support, involvement, counseling, and motivation on learning mathematics. This study employed survey research design of the quantitative approach. The total population of the study was90 students (15 students from each six schools) enrolled in Grade ix of Sindhuli district in 2019. The data were collected through self-structured questionnaire using three points-Likert scale items. Mean and standard deviation of each item were calculated and Chi-square test at 5% level of significance was used to test the hypothesis. The finding of this study shows that the parents of Sindhuli district are very conscious about the study of their children whatever their educational level. This study suggests that parent involvement is an inseparable component to promote mathematical achievement of their offspring.


2018 ◽  
Vol 12 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Rafael Thomazi ◽  
Liciana Vaz de Arruda Silveira ◽  
Paulo José Fortes Villas Boas ◽  
Alessandro Ferrari Jacinto

ABSTRACT Patients with dementia are commonly admitted to inpatient sectors. The aim of this study was to describe the frequency of dementia among elderly inpatients admitted to the Geriatrics Sector of a Brazilian Tertiary University Hospital, and to identify associations between dementia and clinical and sociodemographic factors. Methods: All patients admitted to the Geriatrics Sector of a public Brazilian university-hospital from March 1st 2014 to January 31st 2015 were assessed by geriatricians. The patients were divided into groups "with or without diagnosis of dementia". Univariate analysis was performed between these two groups using the Chi-Square Test, Student's t-test or the Mann-Whitney Test. Results: One hundred and three elderly inpatients, with a mean age of 82 (±7.9) years, were assessed. Overall, 74.7% had low educational level (<4 years), 66% used polypharmacy, 57.2% developed delirium during hospitalization and 59% were totally dependent for basic activities of daily living. The diagnosis of dementia was observed in 59 (57%) subjects. Conclusion: The frequency of dementia was high among the elderly inpatients evaluated. The association between dementia and certain clinical conditions, such as incontinence, delirium and use of psychoactive drugs, was in line with the medical literature.


2011 ◽  
Vol 44 (6) ◽  
pp. 657-660 ◽  
Author(s):  
Graça Maria de Castro Viana ◽  
Maria do Desterro Soares Brandão Nascimento ◽  
Aila de Menezes Ferreira ◽  
Érica Milena Fernandes Rabelo ◽  
João Arnaud Diniz Neto ◽  
...  

INTRODUCTION: One of the important current problems in HIV/AIDS infection is the establishment of epidemiological and laboratorial prognostic parameters during patient follow-up. This study aimed at analyzing the evolution of laboratory tests: CD4 lymphocyte count, viral load, hemoglobin (Hb), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the epidemiological variables sex and age as prognostic factors for survival in progression to death among AIDS patients. METHODS: A retrospective study was conducted using analysis of medical records, and prospective 24-month follow-up of patients with HIV/ AIDS attended at the President Vargas Hospital Outpatient Clinic, a reference center in HIV/ AIDS attendance in the State of Maranhão, Brazil. The study analyzed patients aged 10 to 60 years old, who manifested AIDS and who were not using antiretroviral therapy or had used it for less than 5 years. The Chi-square test was used for statistical analysis. RESULTS: The sample included 100 patients - 57 were current outpatients, and 43 had died. The variables viral load (p=0.726), ALT (p=0.314), sex (p=0.687), and age (p=0.742) were analyzed, and no evidence of association between them and worst prognosis was observed. CONCLUSIONS: A significant relation was verified between low Hb levels (p=0.000) and CD4 (p=0.000) and shorter survival.


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