scholarly journals Evaluation of Burden and Anxiety in Caregivers of Patients with Pediatric Celiac Disease in the COVID-19 Pandemic

2021 ◽  
Author(s):  
Ibrahim Hakan Bucak ◽  
Gokhan Tumgor ◽  
Habip Almis ◽  
Sumeyye Kose ◽  
Cagla Nur Dogan ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Chronic Disease ◽  
Caregiver Burden ◽  
Beck Anxiety Inventory ◽  
Study Group ◽  
Zarit Burden Interview ◽  
Anxiety Levels ◽  
First Time

Abstract Background Anxiety and caregiver burden increase among caregivers for individuals with chronic disease. The purpose of this study was to compare the anxiety levels and caregiver burden among caregivers for cases with pediatric celiac disease (CD) before and during the COVID-19 pandemic. Materials The Zarit Burden Interview (ZBI) and the Beck Anxiety Inventory (BAI) were applied to 29 parents caring for pediatric CD patients in January 2020, when COVID-19 cases had not yet been seen in Turkey. The study was designed prospectively. The scales were also reapplied to the same study group online during the COVID-19 pandemic (May 2020). The results were then compared. Results Parents caring for 29 cases of pediatric CD; 21 mothers (72.4%), six fathers (20.7%), and two aunts (6.9%) took part in the study. Mean ZBI scores before and during the COVID-19 pandemic were 27.51 ± 14.12 (8–73) and 38.68 ± 10.95 (21–57), respectively (p < 0.01). Mean BAI scores before and during the COVID-19 pandemic were 13.27 ± 7.65 (1–27) and 23.48 ± 12.40 (2–48), respectively (p < 0.01). Conclusion Increased anxiety and caregiver burden among caregivers of pediatric CD cases during the COVID-19 pandemic were identified for the first time in the literature in this study.

scholarly journals Vitamin D Status and Its Role in First-Time and Recurrent Urinary Tract Infections in Children: A Case-Control Study

Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 419
Author(s):  
Carmen Muntean ◽  
Maria Săsăran
Keyword(s):  
Vitamin D ◽  
Urinary Tract ◽  
Case Control Study ◽  
Case Control ◽  
Study Group ◽  
Recurrent Utis ◽  
Vitamin D Levels ◽  
Tract Infections ◽  
First Time ◽  
Control Study

Vitamin D has emerged as a key factor in innate immunity. Its involvement in the pathogenesis of urinary tract infections (UTIs) has gained a lot of attention recently. The objective of this study is to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and first-time or recurrent UTIs in children. A prospective, case-control study was conducted on 101 pediatric patients, who were divided into two groups: 59 patients with UTIs and 42 age-matched healthy controls. Serum 25(OH)D was determined in each child and expressed in ng/mL. Vitamin D presented significantly lower values in study group subjects than in healthy controls (p < 0.01). Moreover, a significantly higher prevalence of vitamin D insufficiency and deficiency was found in children with UTIs (p < 0.01). Patients with recurrent UTIs presented significantly lower levels of vitamin D than those with first-time UTIs (p = 0.04). Urinary tract abnormalities did not seem to exercise an additional effect upon vitamin D levels within the study group. In conclusion, first-time and recurrent UTIs are associated with lower vitamin D levels. Further studies are necessary to validate our findings, as well as future longitudinal research regarding efficacy of vitamin D supplementation in children with UTIs.

scholarly journals The Prevalence of Anti-Zein Antibodies: A Comparative Study between Celiac Disease and Irritable Bowel Syndrome

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 649
Author(s):  
Luis Alberto Sánchez-Vargas ◽  
Karina Guadalupe Hernández-Flores ◽  
Francisco Javier Cabrera-Jorge ◽  
José María Remes-Troche ◽  
Job Reyes-Huerta ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Celiac Disease ◽  
Gastrointestinal Disorder ◽  
Newly Diagnosed ◽  
Disease Group ◽  
Immune Mediated ◽  
Healthy Control ◽  
Gliadin Peptides ◽  
Irritable Bowel ◽  
First Time

Celiac disease (CD) is a chronic immune-mediated enteropathy triggered by exposure to dietary gluten in genetically predisposed individuals. In contrast, irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder affecting the large intestine, without an autoimmune component. Here, we evaluated the prevalence of IgA and IgG antibodies to maize zeins (AZA) in patients with CD and IBS. Using an in-house ELISA assay, the IgA and IgG anti-zein antibodies in the serum of 37 newly diagnosed CD (16 biopsy proved and 21 serological diagnosis) and 375 IBS patients or 302 healthy control (HC) subjects were measured. Elevated levels of IgA AZA were found in CD patients compared with IBS patients (p < 0.01) and HC (p < 0.05). CD patients had the highest prevalence (35.1%), followed by IBS (4.3%) and HCs (2.3%) (p < 0.0001). IgG AZA antibodies were not found in any CD patients, IBS patients, or HC subjects. A significant positive correlation was found between IgA AZA with IgA anti-gliadin (AGA, r = 0.34, p < 0.01) and IgA anti-deaminated gliadin peptides (DGP, r = 0.42, p < 0.001) in the celiac disease group. Taken together, our results show for the first time a higher prevalence of AZA IgA antibodies in newly diagnosed CD patients than in IBS patients, confirming a biased immune response to other gliadin-related prolamins such as maize zeins in genetically susceptible individuals.

scholarly journals Introduction and feeding practices of solid food in preterm infants born in Salzburg!

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Edda Hofstätter ◽  
Verena Köttstorfer ◽  
Patricia Stroicz ◽  
Sebastian Schütz ◽  
Lorenz Auer-Hackenberg ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Preterm Infants ◽  
Complementary Feeding ◽  
Study Group ◽  
Early Weaning ◽  
Structured Interviews ◽  
Term Infants ◽  
The Mean ◽  
The Difference

Abstract Background It is shown that meeting the increased nutritional demand of preterm infants from birth is not only important for survival but essentially contributes to the infants` overall development and long-term health. While there are established guidelines for weaning term infants, evidence regarding preterm infants is scarce and less precise. The aim of this study was to identify the current practices on introducing solids to preterm infants amongst caregivers in Salzburg and determine potential reasons for early weaning. Methods Altogether 68 infants born between 24 0/7 and 36 6/7 weeks were recruited and detailed structured interviews with the caregivers were conducted at 17 weeks corrected age. Weight, height and head circumference were collected. Results 52% of the study group received solids before the recommended 17 weeks corrected age. For this group the mean age being 13.77 ± 1.11 weeks corrected age. Premature introduction of solids significantly correlates with exclusively and early formula-feeding. 34% were weaned due to recommendation by their paediatrician. 23% of the preterm infants even received solids before 12 weeks corrected age, putting them at risks for developing obesity, celiac disease and diabetes. Conclusions This study shows the necessity for clear guidelines regarding the introduction of complementary feeding in preterm infants as well as the importance of their implementation. Caregivers should receive information on this topic early enough and they should fully understand the difference between chronological and corrected age.

International Wool Study Group

1950 ◽  
Vol 4 (3) ◽  
pp. 545-546
Keyword(s):  
World Trade ◽  
Study Group ◽  
Wool Production ◽  
The World ◽  
Intergovernmental Collaboration ◽  
First Time

The International Wool Study Group met at London from November 7 to 9, 1949. The meeting noted that world wool production had increased slightly since the war to a point where it was equal to prewar production. The group for the first time decided to release for publication its report on the world wool situation and reports on the wool situation in member countries, unless requested otherwise; On the basis of review it was decided that no immediate problems called for intergovernmental collaboration in world trade of wool; although it was recognized that the problem of surplus stocks which had led to the establishment of the group in 1946 had largely disappeared, it was felt that the group would prove a useful means for the improvement of wool statistics and a useful body to which world wool problems could be referred.

scholarly journals Xanthoma Disseminatum In a Pair of Blind, Deaf Male Twins

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Naveed Natanzi ◽  
David Peng ◽  
Eli Ahdoot ◽  
Sandra Ghatan ◽  
Amy Reinstandler ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Langerhans Cell ◽  
Unknown Etiology ◽  
Inheritance Pattern ◽  
Mucous Membranes ◽  
First Time ◽  
Xanthoma Disseminatum

Xanthoma disseminatum (XD) is a rare normolipemic histiocytic disorder of non-Langerhans cell origin characterized by erythematous to tan/brown papules in flexor surfaces. Considered a generally benign, chronic disease of unknown etiology, XD typically affects the skin, mucous membranes, and less commonly, other organs. To date, there has been no typical or consistent inheritance pattern described, nor has it ever been considered as a component of any known syndrome. We describe, for the first time, two cases of XD in a pair of blind and deaf twin brothers.

scholarly journals Adaptation, linguistic and clinimetric validation of the Bangla version of Zarit Burden Interview

2016 ◽  
Vol 9 (4) ◽  
pp. 181 ◽  
Author(s):  
Farzana Rabin ◽  
Jhunu Shamsun Nahar ◽  
Mohammad S. I. Mullick ◽  
Helal Uddin Ahmed ◽  
Nafia Farzana
Keyword(s):  
Factor Analysis ◽  
Exploratory Factor Analysis ◽  
Caregiver Burden ◽  
Primary Diagnosis ◽  
Validity And Reliability ◽  
Zarit Burden Interview ◽  
Eigen Values ◽  
Diagnosis Of Dementia ◽  
Highly Correlated ◽  
Test Retest Reliability

<p>The aim of this study was to develop a culturally adapted and validated Bangla version of Zarit Burden Interview  (ZBI-B) questionnaire for use in Bangla speaking caregiver of patient with dementia. This study was conducted on 100 caregivers related to consecutively attending outpatients with a previously established primary diagnosis of dementia, according to DSM-IV criteria. Validity and reliability were evaluated by comparing with the caregiver burden inventory (CBI). An exploratory factor analysis with the principle component with varimax rotation was used to detect the factorial structure in observed measurements. To attain the best-fitting structure and the correct number of factors, the following criteria were used: Eigen values &gt;1.0, factor loadings &gt;0.30. The Cronbach’s alpha value was 0.847 for test and 0.839 retest. The intra-class correlation for the test-retest reliability was 0.89. The ZBI score was highly correlated with the CBI score (Pearson’s correlation coefficient, r=0.909, P=.001). From the exploratory factor analysis six factors comprising 20 items were extracted with Eigen values higher than 1.00 accounting for 69% of the total item variance. In conclusion, ZBI-B is valid, reliable and useful for use in clinical contexts and in future studies that could lead to a better understanding of caregiver burden in dementia.</p>

scholarly journals Application Research of Perioperative Clinical Pathway Based on Accelerated Rehabilitation Surgery Strategy in Patients with ERCP

2021 ◽  
Vol 5 (4) ◽  
pp. 113-118
Author(s):  
Xing Yang
Keyword(s):  
Clinical Pathway ◽  
Reference Group ◽  
Anxiety And Depression ◽  
Study Group ◽  
Application Research ◽  
Clinical Nursing ◽  
Accelerated Rehabilitation ◽  
Postoperative Time ◽  
First Time ◽  
Better Than

Objective: To explore the effects of perioperative clinical pathway of accelerated rehabilitation surgery strategy in patients undergoing cholangiopancreatography (ERCP). Methods: Randomly selected 40 patients undergoing ERCP from our hospital which is People’s Hospital, Jingjiang City, for research, and divided the patients into two groups. The 20 patients who were given conventional education methods were set as the reference group, and the 20 patients who were given perioperative clinical pathway care with accelerated rehabilitation surgery strategies were the research group, where the clinical nursing effect of the two groups was statistically compared. Results: According to clinical observation and statistics, the study group’s postoperative time to eat for the first time, time to get out of bed, hospitalization time, and surgical blood loss were better than those of the reference group, P<0.05; the anxiety and depression scores of the study group were lower than those after nursing in the reference group, P<0.05; the incidence of complications in the study group was lower than that in the reference group, and patient satisfaction was higher than that in the reference group, where both P<0.05. Conclusion: The application of perioperative clinical pathway care based on the strategy of accelerated rehabilitation surgery can achieve significant results in ERCP patients, which can effectively improve the surgical indicators of patients and reduce the risk of complications.

Factors emerging from the “Zarit Burden Interview” and predictive variables in a UK sample of caregivers for people with dementia

2018 ◽  
Vol 30 (11) ◽  
pp. 1671-1678 ◽  
Author(s):  
Kerry Johanna Smith ◽  
Catriona George ◽  
Nuno Ferreira
Keyword(s):  
Caregiver Burden ◽  
Experiential Avoidance ◽  
Protective Factor ◽  
Adult Child ◽  
Direct Impact ◽  
Zarit Burden Interview ◽  
People With Dementia ◽  
Health And Social Care ◽  
The Future ◽  
Positive Aspects Of Caregiving

ABSTRACTBackground:Caring for persons with dementia (PWD) can create “caregiver burden,” which is associated with negative outcomes for caregivers and PWD. The ZBI (Zarit Burden Interview) is a widely used unitary measure of caregiver burden. However, recent research has found caregiver burden to be multi-dimensional. The purpose of this study was to explore the factor structure of the ZBI within a sample of UK caregivers. A secondary aim was to identify variables that predicted burden dimensions found.Methods:A total of 110 unpaid community caregivers of PWD completed the ZBI. They also completed the EACQ (Experiential Avoidance in Caregiving Questionnaire), DEX (Dysexecutive Questionnaire), PACS (Positive Aspects of Caregiving Scale), and a demographic questionnaire. ZBI data were analyzed via exploratory factor analysis (principal axis factoring). Relationships between burden factors and other variables were studied using Pearson correlations and multiple regression.Results:Analysis identified three burden factors, namely direct impact of caregiving, uncertainty around the future, and frustration/embarrassment. A direct impact of caregiving and frustration/embarrassment has been found previously. Uncertainty over the future is a new factor, which was predicted by adult-child caregiver role, highlighting that spouses and adult children are likely to have different burden experiences. Additionally, uncertainty over the future and frustration/embarrassment were inversely predicted by PACS, suggesting that being mindful of positive aspects of caregiving may function as a protective factor for burden.Conclusions:This study found caregiver burden to be multi-dimensional and uncovered a novel factor in uncertainty over the future, which warrants further exploration. Burden factors were associated with a range of modifiable variables that could be targeted within health and social care interventions to improve outcomes for caregivers and PWD.

Dimensionality of burden in Alzheimer caregivers: confirmatory factor analysis and correlates of the Zarit Burden interview

2014 ◽  
Vol 26 (9) ◽  
pp. 1455-1463 ◽  
Author(s):  
Sheung-Tak Cheng ◽  
Timothy Kwok ◽  
Linda C. W. Lam
Keyword(s):  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Exploratory Factor Analysis ◽  
Factor Structure ◽  
Caregiver Burden ◽  
Care Recipient ◽  
Factor Analyses ◽  
Confirmatory Factor Analyses ◽  
Zarit Burden Interview ◽  
Confirmatory Factor

ABSTRACTBackground:To investigate dimensions of caregiver burden through factor analysis of the Zarit Burden Interview (ZBI), and to examine predictors of different dimensions of burden.Methods:Confirmatory factor analyses were performed on 395 Hong Kong Chinese Alzheimer caregivers to examine whether several proposed factor structures fit the data well. Subsequently, participants were split into two roughly equal subsamples, for the purpose of identifying the most optimal factor structure through exploratory factor analysis in Sample A (n = 183) and an independent verification through confirmatory factor analysis in Sample B (n = 212). ZBI subscales representing the established factors were correlated with caregiver and care-recipient variables known to be associated with burden.Results:Confirmatory factor analyses showed that factor models reported elsewhere did not fit the data well. Subsequently, exploratory factor analysis in Sample A suggested a 4-factor structure. After dropping three items due to poor factor loadings, the 4-factor structure was found to fit the data moderately well in Sample B. The four factors tapped personal strain, captivity, self-criticism, and loss of control. However, self-criticism was basically unrelated to the other three factors and showed a rather different pattern of correlations with caregiver and care-recipient variables. Self-criticism was more common among child caregivers and those who did not live with the care-recipient and was less involved in day-to-day care, yet feeling obligated and close to the care-recipient.Conclusions:The dimensions of caregiver burden may be culturally specific. More research is needed to examine cultural considerations in measuring caregiver burden.

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