scholarly journals Application Research of Perioperative Clinical Pathway Based on Accelerated Rehabilitation Surgery Strategy in Patients with ERCP

2021 ◽  
Vol 5 (4) ◽  
pp. 113-118
Author(s):  
Xing Yang

Objective: To explore the effects of perioperative clinical pathway of accelerated rehabilitation surgery strategy in patients undergoing cholangiopancreatography (ERCP). Methods: Randomly selected 40 patients undergoing ERCP from our hospital which is People’s Hospital, Jingjiang City, for research, and divided the patients into two groups. The 20 patients who were given conventional education methods were set as the reference group, and the 20 patients who were given perioperative clinical pathway care with accelerated rehabilitation surgery strategies were the research group, where the clinical nursing effect of the two groups was statistically compared. Results: According to clinical observation and statistics, the study group’s postoperative time to eat for the first time, time to get out of bed, hospitalization time, and surgical blood loss were better than those of the reference group, P<0.05; the anxiety and depression scores of the study group were lower than those after nursing in the reference group, P<0.05; the incidence of complications in the study group was lower than that in the reference group, and patient satisfaction was higher than that in the reference group, where both P<0.05. Conclusion: The application of perioperative clinical pathway care based on the strategy of accelerated rehabilitation surgery can achieve significant results in ERCP patients, which can effectively improve the surgical indicators of patients and reduce the risk of complications.

2021 ◽  
Vol 5 (6) ◽  
pp. 79-83
Author(s):  
Guixia Jiang

Objective: To study the clinical nursing effect of early rehabilitation nursing on stroke patients with hemiplegia in neurology department. Methods: Stroke patients with hemiplegia treated in our hospital from March 2018 to March 2020 were selected for the present study. Twenty patients in each group were divided into two groups by random number table method, either in experimental group or control group. Routine nursing was used in the control group, while early rehabilitation nursing was carried out in the experimental group. The clinical nursing effect of the two groups of patients was compared. Results: After nursing, the neurological function of the patients was significantly improved (P < 0.05), the improvement of the experimental group was better than that of the control group (P < 0.01), the daily activities of the patients in the experimental group were significantly improved, and the score of the experimental group was higher than that of the control group (P < 0.05). After nursing, anxiety and depression scores in the experimental group were significantly lower than those in the control group (P < 0.05), and the recovery of limb function in the experimental group was better than that in the control group (P < 0.05). Conclusion: The implementation of early rehabilitation nursing measures plays an important role in the recovery of stroke patients with hemiplegia by promoting the recovery of neurological function, improving the psychological state of patients, and promoting the recovery of limbs.


Trauma ◽  
2021 ◽  
pp. 146040862110261
Author(s):  
Arham Qureshi ◽  
Edward Dickenson ◽  
Peter Wall

Introduction Approximately 16% of the world’s burden of disease is attributable to traumatic injury. Psychological symptoms, including post-traumatic stress disorder (PTSD), are prevalent in this population and impact recovery from physical injury. Nevertheless, mental health has not been considered to the same degree as physical health. Psychological interventions are used widely as treatments for PTSD. Methods Systematic searches of computerised databases were conducted. Randomised controlled trials of psychological treatments for PTSD following major physical civilian trauma were included. The main outcome measure was clinician-assessed symptoms of PTSD (CAPS), with findings for anxiety and depression also reported. Included studies data were extracted and entered using RevMan 5.3 software. Quality assessments were performed, and data were analysed for summary effects. Results 10 studies were included. With regard to CAPS <6 months, individual CBT did significantly better than usual care/wait list (SMD (95% CI) = −1.24 [−1.82, −0.67]) and non-CBT treatments (SMD (95% CI) = −1.32 [−2.64, −0.04]). Non-CBT treatments were not significantly better than usual care/wait list (SMD (95% CI) −1.40 [−2.91, 0.11]). CBT was superior to usual care/wait list for reducing depressive (SMD (95% CI) −0.67 [−0.98, −0.37]) and anxiety (SMD (95% CI) −0.70 [−1.22, −0.18]) symptoms both in the shorter and longer term. Conclusion Individual CBT was superior to wait list/usual care, and there was limited evidence for non-CBT treatments in reducing clinician and self-rated PTSD, depressive and anxiety symptoms in the shorter term; however, the latter comparison was based on few studies with small sample sizes. Longer-term effects of treatments remain uncertain. There is a need for adequately powered RCTs investigating PTSD treatments following major physical civilian trauma in the longer term. There was considerable heterogeneity in the studies, so care must be taken in interpreting the results of this review.


Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 419
Author(s):  
Carmen Muntean ◽  
Maria Săsăran

Vitamin D has emerged as a key factor in innate immunity. Its involvement in the pathogenesis of urinary tract infections (UTIs) has gained a lot of attention recently. The objective of this study is to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and first-time or recurrent UTIs in children. A prospective, case-control study was conducted on 101 pediatric patients, who were divided into two groups: 59 patients with UTIs and 42 age-matched healthy controls. Serum 25(OH)D was determined in each child and expressed in ng/mL. Vitamin D presented significantly lower values in study group subjects than in healthy controls (p < 0.01). Moreover, a significantly higher prevalence of vitamin D insufficiency and deficiency was found in children with UTIs (p < 0.01). Patients with recurrent UTIs presented significantly lower levels of vitamin D than those with first-time UTIs (p = 0.04). Urinary tract abnormalities did not seem to exercise an additional effect upon vitamin D levels within the study group. In conclusion, first-time and recurrent UTIs are associated with lower vitamin D levels. Further studies are necessary to validate our findings, as well as future longitudinal research regarding efficacy of vitamin D supplementation in children with UTIs.


Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 741
Author(s):  
Zheng Wang ◽  
Ge Yang ◽  
Biao Ren ◽  
Yuan Gao ◽  
Xian Peng ◽  
...  

The infection of Enterococcus faecalis and its interacting microorganisms in the root canal could cause persistent apical periodontitis (AP). Antibacterial root canal sealer has favorable prospects to inhibit biofilms. The purpose of this study was to investigated the antibacterial effect of root canal sealer containing dimethylaminododecyl methacrylate (DMADDM) on persistent AP in beagle dogs for the first time. Persistent AP was established by a two-step infection with Enterococcus faecalis and multi-bacteria (Enterococcus faecalis, Lactobacillus acidophilus, Actinomycesnaeslundii, Streptococcus gordonii). Root canal sealer containing DMADDM (0%, 1.25%, 2.5%) was used to complete root canal filling. The volume of lesions and inflammatory grade in the apical area were evaluated by cone beam computer tomography (CBCT) and hematoxylin-eosin staining. Both Enterococcus-faecalis- and multi-bacteria-induced persistent AP caused severe apical destruction, and there were no significant differences in pathogenicity between them. DMADDM-modified sealer significantly reduced the volume of periapical lesion and inflammatory grade compared with the control group, among them, the therapeutic effect of the 2.5% group was better than the 1.25% group. In addition, E.faecalis-induced reinfection was more sensitive to the 2.5% group than multi-bacteria reinfection. This study shows that root canal sealer containing DMADDM had a remarkable therapeutic effect on persistent AP, especially on E. faecalis-induced reinfection.


1998 ◽  
Vol 11 (1) ◽  
pp. 551-551
Author(s):  
N. Zacharias ◽  
M.I. Zacharias ◽  
C. de Vegt ◽  
C.A. Murray

The Second Cape Photographic Catalog (CPC2) contains 276,131 stars covering the entire Southern Hemisphere in a 4-fold overlap pattern. Its mean epoch is 1968, which makes it a key catalog for proper motions. A new reduction of the 5687 plates using on average 40 Hipparcos stars per plate has resulted in a vastly improved catalog with a positional accuracy of about 40 mas (median value) per coordinate, which comes very close to the measuring precision. In particular, for the first time systematic errors depending on magnitude and color can be solved unambiguously and have been removed from the catalog. In combination with the Tycho Catalogue (mean epoch 1991.25) and the upcoming U.S. Naval Observatory CCD Astrograph Catalog (UCAC) project proper motions better than 2 mas/yr can be obtained. This will lead to a vastly improved reference star catalog in the Southern Hemisphere for the final Astrographic Catalogue (AC) reductions, which will then provide propermotions for millions of stars when combined with new epoch data. These data then will allow an uncompromised reduction of the southern Schmidt surveys on the International Celestial Reference System (ICRS).


Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 298
Author(s):  
Yefen Zhu ◽  
Yanlei Kang ◽  
Ling Zhu ◽  
Kaxi Yu ◽  
Shuai Chen ◽  
...  

Canagliflozin (CG) was a highly effective, selective and reversible inhibitor of sodium-dependent glucose co-transporter 2 developed for the treatment of type 2 diabetes mellitus. The crystal structure of CG monohydrate (CG-H2O) was reported for the first time while CG hemihydrate (CG-Hemi) had been reported in our previous research. Solubility and dissolution rate results showed that the solubility of CG-Hemi was 1.4 times higher than that of CG-H2O in water and hydrochloric acid solution, and the dissolution rates of CG-Hemi were more than 3 folds than CG-H2O in both solutions. Hirshfeld surface analysis showed that CG-H2O had stronger intermolecular forces than CG-Hemi, and water molecules in CG-H2O participated three hydrogen bonds, forming hydrogen bond networks. These crystal structure features might make it more difficult for solvent molecules to dissolve CG-H2O than CG-Hemi. All these analyses might explain why the dissolution performance of CG-Hemi was better than CG-H2O. This work provided an approach to predict the dissolution performance of the drug based on its crystal structure.


1950 ◽  
Vol 4 (3) ◽  
pp. 545-546

The International Wool Study Group met at London from November 7 to 9, 1949. The meeting noted that world wool production had increased slightly since the war to a point where it was equal to prewar production. The group for the first time decided to release for publication its report on the world wool situation and reports on the wool situation in member countries, unless requested otherwise; On the basis of review it was decided that no immediate problems called for intergovernmental collaboration in world trade of wool; although it was recognized that the problem of surplus stocks which had led to the establishment of the group in 1946 had largely disappeared, it was felt that the group would prove a useful means for the improvement of wool statistics and a useful body to which world wool problems could be referred.


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