Morphometric analysis of myofibre development in the adductor femoris muscle of single and twin fetal lambs

2000 ◽  
Vol 12 (6) ◽  
pp. 329 ◽  
Author(s):  
S. A. McCoard ◽  
W. C. McNabb ◽  
S. W. Peterson ◽  
S. N. McCutcheon ◽  
P. M. Harris
Keyword(s):  
Sampling Site ◽  
Muscle Growth ◽  
Morphological Characteristics ◽  
Distal Region ◽  
Fetal Life ◽  
Cross Sectional ◽  
The Impact ◽  
Femoris Muscle ◽  
Selection Of

Cellular development of the adductor femoris muscle from twin and single fetuses was studied at 140 days gestation to evaluate the effect of moderate fetal growth retardation on myofibre development. Twin fetuses had lower bodyweights (13%) and disproportionately small adductor femoris muscle weights (22%) compared with single fetuses. Reduced muscle mass was associated with smaller myofibre cross-sectional areas (CSA) and lower DNA content (22%), indicative of fewer myonuclei and retarded myofibre hypertrophy. Myofibre number and the phenotypic maturation of the myofibres were similar between twins and singletons. These results indicate that even modest growth restriction during fetal life can negatively influence myofibre hypertrophy, highlighting the importance of fetal nutrition for muscle growth. Large muscles, such as the adductor femoris, have intrafascicularly terminating myofibres, which necessitates accurate sampling of the muscle when investigating possible perturbations in morphological characteristics (e.g. between singletons and twins). The second objective of the present study was to investigate the impact of the sampling site on the morphological parameters of the adductor femoris muscle. The apparent total myofibre number decreased from the proximal to the distal region of the adductor femoris muscle. The apparent number of slow-twitch fibres also decreased from the proximal to the medial region, but was not different between the medial and distal regions of the muscle. Similarly, myofibre CSA differed between the medial and distal regions. These results indicate that, particularly with large muscles, such as the adductor femoris, which has intrafascicularly terminating myofibres, single site sampling for the determination of morphological fibre characteristics may generate misleading results and that careful selection of the sampling area may be necessary.

Determination of integral indicators characterizing the possibility of accommodating the evacuated population in the territory of the Republic of Kazakhstan

2020 ◽  
pp. 154851292097028
Author(s):  
Yernar Zh Akimbayev ◽  
Zhumabek Kh Akhmetov ◽  
Murat S Kuanyshbaev ◽  
Arman T Abdykalykov ◽  
Rashid V Ibrayev
Keyword(s):  
Statistical Data ◽  
Armed Conflicts ◽  
Security Issues ◽  
Inaccurate Information ◽  
The Subject ◽  
The Republic ◽  
The Impact ◽  
Integrated Indicators ◽  
Selection Of

Studying the historical facts of past wars and armed conflicts and natural and man-made emergencies, today in the Republic of Kazakhstan one of the most important security issues is the preparation and organization of the evacuation of the population from possible dangerous zones, taking into account the emergence of new threats to the country’s security. The paper presents an algorithm for constructing universal scales of the distribution function of opportunities by types of support and rebuilding them into subject scales using display functions. The purpose of the paper is to determine the integral indicators characterizing the possibility of accommodation of the evacuated population and the impact on resources during relocation. On the subject scales of cities and districts of the region, indicators of the possibility of relocation of a certain amount of the evacuated population by types of support and indicators characterizing the impact on the district’s resources during resettlement of a certain amount of the evacuated population are determined. It was concluded that the use of integrated indicators allows the selection of areas to accommodate the evacuated population without the use of statistical data, in conditions of incomplete and inaccurate information. The presented method does not replace traditional methods based on classical methods of territory assessment by the level of life sustenance, but also allows their reasonable combination with the experience of specialists in this field, taking into account the incompleteness, uncertainty, and inconsistency of the initial data of the study area, which does not allow the application of existing methods.

scholarly journals Functional-semantic aspects of translation of psychological terminological phrases of English language

2020 ◽  
pp. 1-15 ◽  
Author(s):  
Elena Anatol'evna Balygina ◽  
Yuliya Vladimirovna Yarovikova ◽  
Tat'yana Viktorovna Ermolova ◽  
Oksana Aleksandrovna Krukovskaya
Keyword(s):  
English Language ◽  
Translation Process ◽  
Translation Strategy ◽  
Semantic Development ◽  
The Impact ◽  
Selection Of ◽  
The Way

Multiple scientific works are dedicated to studying the impact of linguistic factors upon the translation process. However, relevant remains the task of determining dependence of the translation strategy on the peculiarities of semantic development and functionality of terminological units. This article examines the functional-semantic aspects of translation of the adjective-substantive terminological phrases of English language that reflects the scientific notions of psychology. An attempt is made to develop the methods for translating terminological phrases that would consider syntagmatic aspects of interaction of the meanings of its components. Attention is focused on determination of the impact of peculiarities of terminological meaning of terminological phrase upon the choice of its conveying in translation. A conclusion is made that the translation process of terminological phrases from English to Russian are influenced by such factors, as the level of semantic closeness of terminological phrases and communicative significance of its adjective component. In conclusion, the author discusses strategies of selection of the way of translation of terminological phrases, taking into account the aforementioned factors.

The Determination of Stagnant Rate of Servo System Based on Adaptive Chatter Algorithm

2013 ◽  
Vol 860-863 ◽  
pp. 1787-1790
Author(s):  
Ting Zhao ◽  
Xiao Zhi Qiu ◽  
Ding Cai ◽  
Bao Hua Huang
Keyword(s):  
Dead Zone ◽  
Servo System ◽  
Signal Frequency ◽  
Determination Method ◽  
Dynamic Effects ◽  
Change Rate ◽  
The Dead ◽  
The Impact ◽  
Selection Of

The current determination of stagnant rate cannot eliminate the dynamic effects, especially the change rate of speed. Consider the problem of the current determination of stagnant rate, this work presents one determination method based on adaptive chatter algorithm .Simulation shows it can eliminate the impact of dynamics effectively. The method achieves the measurement online due to the signal of chatter can adapt to the dead zone of servo system. At last, the selection of the signal frequency is discussed.

scholarly journals Effect of single tube sections on the structural safety of Chinese solar greenhouse skeletons

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xingan Liu ◽  
Zhenkun Li ◽  
Lei Zhang ◽  
Yu Liu ◽  
Yiming Li ◽  
...  
Keyword(s):  
Material Selection ◽  
Selection Process ◽  
Load Condition ◽  
Structural Features ◽  
Structural Safety ◽  
Element Analysis ◽  
Cross Sectional ◽  
Single Tube ◽  
The Impact ◽  
Selection Of

AbstractIn recent years, the use of single-tube skeletons for the construction of Chinese solar greenhouses has increased. As a consequence, during the selection of the construction materials, the safety of these structures has become an important issue. The single tube section has various forms, but there is no scientific theory to guide the selection process. To the best of our knowledge, the scientific analysis of the impact of single pipe cross section on the safety of greenhouse skeleton has not been addressed so far. In this context, the finite element analysis software was used to calculate and analyze the stress elements, displacement of round tube, Ω tube, elliptic tube and square tube under the same load conditions. We used the Chinese Standard values as a reference and analyzed structural features of different sizes and thicknesses of the greenhouse steel skeleton sections under non-uniform snow load. The results showed that, under the same load condition, the maximum stress in the four skeleton materials was all located at the connection of the transverse tension bar and the front roof. In addition, under same load condition, the greenhouse skeleton with elliptic tube presented the smallest cross-sectional displacement between the different materials tested. The effect of increasing the size of the greenhouse frame was better than that of increasing the greenhouse material thickness. All this work will provide theoretical guidance to the material selection of this structure.

scholarly journals Progressive Poling of Large Area, High r33 Electro-Optic Polymer SEO100c

2021 ◽  
Vol 11 (17) ◽  
pp. 8108
Author(s):  
Michael Maurer ◽  
Evan Gawron ◽  
Christopher Middlebrook
Keyword(s):  
Extended Period ◽  
High Yield ◽  
Large Area ◽  
Device Structure ◽  
Poling Process ◽  
Electro Optic ◽  
Waveguide Modulator ◽  
The Impact ◽  
Selection Of

SEO100c, an EO-polymer, has been reported of having an r33 in excess of 100 pm/V. Experimental poling research was performed on rib waveguide modulator for device design and development. Reported is the determination of the impact that temperature and voltage have on the poling of a SEO100c waveguide device in order to maximize the r33 while avoiding damage to the device structure ensuring high yield in manufacture. The poling process is shown to have a nonlinear relationship between r33 and poling field aiding in the selection of achievable poling voltages for required r33 values. Device thermal stability is quantified and reported for the complete poling process and the impacts upon r33. Investigation into the possible relaxation of device r33 is measured over an extended period demonstrating desirable use within deployable devices.

Influence of varying degrees of malnutrition on IGF-I expression in the rat diaphragm

2003 ◽  
Vol 95 (2) ◽  
pp. 555-562 ◽  
Author(s):  
Michael I. Lewis ◽  
Hongyan Li ◽  
Zhi-Shen Huang ◽  
Manmohan S. Biring ◽  
Bojan Cercek ◽  
...  
Keyword(s):  
Muscle Protein ◽  
Muscle Growth ◽  
The Body ◽  
Diaphragm Muscle ◽  
Fiber Types ◽  
Mrna Levels ◽  
Adult Rats ◽  
Cross Sectional ◽  
Igf I ◽  
The Impact

This study evaluated the impact of varying degrees of prolonged malnutrition on the local insulin-like growth factor-I (IGF-I) system in the costal diaphragm muscle. Adult rats were provided with either 60 or 40% of usual food intake over 3 wk. Nutritionally deprived (ND) animals (i.e., ND60 and ND40) were compared with control (Ctl) rats fed ad libitum. Costal diaphragm fiber types and cross-sectional areas were determined histochemically. Costal diaphragm muscle IGF-I mRNA levels were determined by RT-PCR. Serum and muscle IGF-I peptide levels were determined by using a rat-specific radioimmunoassay. The body weights of Ctl rats increased by 5%, whereas those of ND60 and ND40 animals decreased by 16 and 26%, respectively. Diaphragm weights were reduced by 17 and 27% in ND60 and ND40 animals, respectively, compared with Ctl. Diaphragm fiber proportions were unaffected by either ND regimen. Significant atrophy of both type IIa and IIx fibers was noted in the ND60 group, whereas atrophy of all three fiber types was observed in the diaphragm of ND40 rats. Serum IGF-I levels were reduced by 62 and 79% in ND60 and ND40 rats, respectively, compared with Ctl. Diaphragm muscle IGF-I mRNA levels in both ND groups were similar to those noted in Ctl. In contrast, IGF-I concentrations were reduced by 36 and 42% in the diaphragm muscle of ND60 and ND40 groups, respectively, compared with Ctl. We conclude that the local (autocrine/paracrine) muscle IGF-I system is affected in our models of prolonged ND. We propose that this contributes to disordered muscle protein turnover and muscle cachexia with atrophy of muscle fibers. This is particularly so in view of recent data demonstrating the importance of the autocrine/paracrine system in muscle growth and maintenance of fiber size.

scholarly journals ‘Don’t play if you can’t win’: does economic inequality undermine political equality?

2019 ◽  
Vol 11 (3) ◽  
pp. 395-413 ◽  
Author(s):  
Armin Schäfer ◽  
Hanna Schwander
Keyword(s):  
Income Inequality ◽  
Voter Turnout ◽  
Economic Inequality ◽  
Political Equality ◽  
Local Data ◽  
Cross Sectional ◽  
Time Period ◽  
The Impact ◽  
The Relationship ◽  
Selection Of

AbstractIn this paper, we investigate whether income inequality negatively affects voter turnout. Despite some progress, the answer to this question is still debated due to methodological disagreements and differences in the selection of countries and time periods. We contribute to this debate by triangulating data and methods. More specifically, we use three kinds of data to resolve the question: first, we use cross-sectional aggregate data of 21 OECD countries in the time period from 1980 to 2014 to study the relationship between inequality and electoral participation. Second, we zoom in on the German case and examine local data from 402 administrative districts between 1998 and 2017. Focusing on within-country variation eliminates differences that are linked to features of the political system. Finally, we combine survey data with macro-data to investigate the impact of inequality on individual voting. This final step also allows us to test whether the effect of income inequality on voter turnout differs across income groups. Taken together, we offer the most comprehensive analysis of the impact of social inequality on political inequality to date. We corroborate accounts that argue that economic inequality exacerbates participatory inequality.

scholarly journals Genetic and genomic analyses of musculoskeletal differences between BEH and BEL strains

2013 ◽  
Vol 45 (20) ◽  
pp. 940-947 ◽  
Author(s):  
Arimantas Lionikas ◽  
Audrius Kilikevicius ◽  
Lutz Bünger ◽  
Caroline Meharg ◽  
Andrew M. Carroll ◽  
...  
Keyword(s):  
Body Weight ◽  
Soleus Muscle ◽  
Muscle Growth ◽  
Morphological Characteristics ◽  
Nucleotide Polymorphisms ◽  
Causative Gene ◽  
Muscle Weight ◽  
Cross Sectional ◽  
Fiber Number ◽  
Muscle Fiber Number

Berlin high (BEH) and Berlin low (BEL) strains selected for divergent growth differ threefold in body weight. We aimed at examining muscle mass, which is a major contributor to body weight, by exploring morphological characteristics of the soleus muscle (fiber number and cross sectional area; CSA), by analyzing the transcriptome of the gastrocnemius and by initiating quantitative trait locus (QTL) mapping. BEH muscles were four to eight times larger than those of BEL. In substrain BEH+/+, mutant myostatin was replaced with a wild-type allele; however, BEH+/+muscles still were two to four times larger compared with BEL. BEH soleus muscle fibers were two times more numerous ( P < 0.0001) and CSA was two times larger ( P < 0.0001) compared with BEL. In addition, soleus femoral attachment anomaly (SFAA) was observed in all BEL mice. One significant (Chr 1) and four suggestive (Chr 3, 4, 6, and 9) muscle weight QTLs were mapped in a 21-day-old F2 intercross ( n = 296) between BEH and BEL strains. The frequency of SFAA incidence in the F2 and in the backcross to BEL strain (BCL) suggested the presence of more than one causative gene. Two suggestive SFAA QTLs were mapped in BCL; however, their peak markers were not associated with the phenotype in F2. RNA-Seq analysis revealed 2,148 differentially expressed ( P < 0.1) genes and 45,673 single nucleotide polymorphisms and >2,000 indels between BEH+/+ and BEL males. In conclusion, contrasting muscle traits and genomic and gene expression differences between BEH and BEL strains provide a promising model for the search for genes involved in muscle growth and musculoskeletal morphogenesis.

The impact of the food-based and nutrient-based standards on lunchtime food and drink provision and consumption in secondary schools in England

2013 ◽  
Vol 16 (6) ◽  
pp. 1052-1065 ◽  
Author(s):  
Jo Nicholas ◽  
Lesley Wood ◽  
Clare Harper ◽  
Michael Nelson
Keyword(s):  
Secondary Schools ◽  
Fruit Juice ◽  
School Lunches ◽  
School Food ◽  
Cross Sectional ◽  
Nationally Representative ◽  
Food And Drink ◽  
The Impact ◽  
Energy And Nutrient Intake ◽  
Selection Of

AbstractObjectivesTo assess lunchtime provision of food and drink in English secondary schools and the choices and consumption of food and drink by pupils having school lunches, and to compare provision in 2011 with that in 2004.DesignCross-sectional data collected between October 2010 and April 2011. In each school, food and drink provision, including portion weights and number of portions of each item served at lunchtime, were recorded over five consecutive days. Caterers provided recipe information.SettingEngland.SubjectsA random selection of 5969 pupils having school lunches in a nationally representative sample of eighty secondary schools in England.ResultsCompared with 2004, significantly more schools in 2011 provided main dishes, vegetables and salads, water, fruit juice and other drinks on 4 or 5 d/week (P < 0·005). The number of schools offering items not permitted under the food-based standards for school food on 4 or 5 d/week fell significantly over time (P < 0·005), while the number not offering these items on any day increased significantly (P < 0·005). Meals eaten by pupils were well-balanced in relation to macronutrients.ConclusionsLunchtime food provision and consumption in secondary schools have improved considerably since 2004, following the introduction of new compulsory standards for school food in 2009. To maximise their energy and nutrient intake at lunchtime, pupils should be encouraged to select a full meal, and to take and eat more fruit and vegetables. Schools also need continued support to increase the micronutrient content of menus and recipes.

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