Recovery of Aliphatic Fatty Acids from Red Seaweed Champia parvula (C. Agardh) and Its Antifungal Action

The red seaweed group (Rhodophyta) is one of the phyla of macroalgae, among the groups Phaeophyceae and Chlorophyta, brown and green seaweeds, respectively. Nowadays, all groups of macroalgae are getting the attention of the scientific community due to the bioactive substances they produce. Several macroalgae products have exceptional properties with nutraceutical, pharmacological, and biomedical interest. The main compounds studied are the fatty acids, pigments, phenols, and polysaccharides. Polysaccharides are the most exploited molecules, which are already widely used in various industries and are, presently, entering into more advanced applications from the therapeutic point of view. The focuses of this review are the red seaweeds’ compounds, its proprieties, and its uses. Moreover, this work discusses new possible applications of the compounds of the red seaweeds.

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Polysiphonia japonica Extract Attenuates Palmitate-Induced Toxicity and Enhances Insulin Secretion in Pancreatic Beta-Cells

Oxidative Medicine and Cellular Longevity ◽

10.1155/2018/4973851 ◽

2018 ◽

Vol 2018 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Seon-Heui Cha ◽

Hyun-Soo Kim ◽

Yongha Hwang ◽

You-Jin Jeon ◽

Hee-Sook Jun

Keyword(s):

Fatty Acids ◽

Insulin Secretion ◽

Fatty Acid ◽

Protective Effect ◽

Functional Food ◽

Pancreatic Beta Cells ◽

Cell Loss ◽

Transgenic Zebrafish ◽

Zebrafish Embryos ◽

Red Seaweed

Beta-cell loss is a major cause of the pathogenesis of diabetes. Elevated levels of free fatty acids may contribute to the loss of β-cells. Using a transgenic zebrafish, we screened ~50 seaweed crude extracts to identify materials that protect β-cells from free fatty acid damage. We found that an extract of the red seaweed Polysiphonia japonica (PJE) had a β-cell protective effect. We examined the protective effect of PJE on palmitate-induced damage in β-cells. PJE was found to preserve cell viability and glucose-induced insulin secretion in a pancreatic β-cell line, Ins-1, treated with palmitate. Additionally, PJE prevented palmitate-induced insulin secretion dysfunction in zebrafish embryos and mouse primary islets and improved insulin secretion in β-cells against palmitate treatment. These findings suggest that PJE protects pancreatic β-cells from palmitate-induced damage. PJE may be a potential therapeutic functional food for diabetes.

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Calliblepharis jubata Cultivation Potential—A Comparative Study between Controlled and Semi-Controlled Aquaculture

Applied Sciences ◽

10.3390/app10217553 ◽

2020 ◽

Vol 10 (21) ◽

pp. 7553

Author(s):

Glacio Souza Araujo ◽

João Cotas ◽

Tiago Morais ◽

Adriana Leandro ◽

Sara García-Poza ◽

...

Keyword(s):

Fatty Acids ◽

Food Industry ◽

Nutritional Value ◽

Human Consumption ◽

Growing Up ◽

Red Seaweed ◽

Biochemical Compounds ◽

Biological Compounds ◽

Primary Producer ◽

Cultivation Techniques

Calliblepharis jubata is an edible red seaweed and a carrageenan primary producer, considered native in Figueira da Foz (Portugal). C. jubata has the particularity of producing only one kind of carrageenan, the iota fraction. However, this seaweed is not yet valuable for the food industry or even for human consumption. In this work, we characterize important biochemical compounds of C. jubata growing up within different cultivation techniques and wild specimens. The aim of this work is to know if there are differences between the biological compounds of interest and identify the advantages for human consumption and the food industry. The results supported the nutritional value of the seaweed, where the ones from inshore cultivation (T) were more identical to the wild specimens (F), than the indoor C. jubata (A, B, C). The parameters analyzed were fatty acids, carbohydrates and carrageenan content.

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Seasonal Changes in the Nutritional Composition of Agarophyton vermiculophyllum (Rhodophyta, Gracilariales) from the Center of Portugal

Foods ◽

10.3390/foods10051145 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1145

Author(s):

Clélia Afonso ◽

Ana Patrícia Correia ◽

Marta V. Freitas ◽

Teresa Baptista ◽

Marta Neves ◽

...

Keyword(s):

Fatty Acids ◽

Environmental Conditions ◽

Seasonal Changes ◽

Nutritional Value ◽

Nutritional Composition ◽

Red Seaweed ◽

High Concentration ◽

Nutritional Profile ◽

Low Levels ◽

Comprehensive Study

Seaweeds exhibit high nutritional value due to a balanced concentration of proteins, vitamins and minerals, a high concentration of low digestibility polysaccharides, and reduced levels of lipids, many of which are n-3 and n-6 fatty acids. The species Agarophyton vermiculophyllum is no exception and, as such, a comprehensive study of the chemical and nutritional profile of this red seaweed was carried out for 1 year. Seasonal variations in moisture, ash, protein and amino acids content, crude fibers, ascorbic acid, agar, lipids, and the corresponding fatty acid profile, were analyzed. We found low levels of fatty acids and a high protein content, but also noticed interesting seasonal change patterns in these compounds. The present study gives insights on the environmental conditions that can lead to changes in the nutritional composition of this species, aiming, therefore, to bring new conclusions about the manipulation of environmental conditions that allow for maximizing the nutritional value of this seaweed.

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Effect of proteins from the red seaweed Hypnea musciformis (Wulfen) Lamouroux on the growth of human pathogen yeasts

Brazilian Archives of Biology and Technology ◽

10.1590/s1516-89132006000700008 ◽

2006 ◽

Vol 49 (6) ◽

pp. 915-921 ◽

Cited By ~ 21

Author(s):

Rossana Aguiar Cordeiro ◽

Valdirene Moreira Gomes ◽

Ana Fontenele Urano Carvalho ◽

Vânia Maria Maciel Melo

Keyword(s):

Candida Albicans ◽

Protein Fraction ◽

Inhibitory Action ◽

Red Seaweed ◽

Human Pathogen ◽

Hypnea Musciformis ◽

Glucanase Activity ◽

Antifungal Potential ◽

Antifungal Action ◽

Specific Activities

A protein fraction, rich in lectin, obtained from the red seaweed Hypnea musciformis by precipitation with ammonium sulfate (F40/70) was screened for chitinase and beta-1,3-glucanase activity and assessed for antifungal potential against the human pathogen yeasts Candida albicans and C. guilliermondii. The F40/70 fraction showed chitinase and beta-1,3-glucanase enzymes, with specific activities of 276.43 and 1880.7 Units.mg -1 protein, respectively. It was capable of inhibiting the growth of C. guilliermondii at the concentrations of 45, 100 and 450 µg protein.ml -1 but it showed only a discrete inhibition against C. albicans irrespective of the tested concentrations. The inhibitory action was shown to be fungistatic and the presence of the glycoprotein fetuin, for which the lectin in the fraction had affinity, abolished the antifungal action. The complete growth recovery following fetuin treatment indicated that chitinase and beta-1,3-glucanase were not involved in the growth inhibition of these yeasts.

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FATTY ACID COMPOSITION AND PROSTAGLANDIN CONTENT OF THE RED SEAWEED Gracilaria sp. FROM INDONESIA

Indonesian Aquaculture Journal ◽

10.15578/iaj.7.1.2012.49-54 ◽

2012 ◽

Vol 7 (1) ◽

pp. 49

Author(s):

Muhammad Ikbal Illijas ◽

Arifuddin Arifuddin ◽

Luqman Saleh ◽

Yutaka Itabashi

Keyword(s):

Fatty Acids ◽

Gas Chromatography ◽

Arachidonic Acid ◽

Fatty Acid Composition ◽

Fatty Acid ◽

Acid Composition ◽

Total Lipid ◽

Red Alga ◽

Red Seaweed ◽

Fatty Acids Composition

High content of polyunsaturated fatty acids (PUFAs) such as arachidonic and eicosapentaenoic acids are typical for the red alga. Analysis of fatty acid composition and prostaglandin content was conducted in the red alga Gracilaria sp. from Indonesia. Total lipid of the alga was extracted with CHCl3-MeOH (2:1, v/v). Analysis of the fatty acids composition was performed on gas chromatography (GC) equipped with omega wax column (30 m x 0,32 mm i.d., Supelco, PA, USA) and analysis of prostaglandins were carried out by HPLC on ODS column (Mightysil RP-18 GP, 250 mm x 4.6 mm, 5 μm). The content of fatty acids high for were palmitic acid (50%) and arachidonic acid (26.9%), whereas prostaglandin E2 was identified and found lower concentration (44.2 μg/gram total lipid).

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