scholarly journals A Comprehensive Review of the Nutraceutical and Therapeutic Applications of Red Seaweeds (Rhodophyta)

Life ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 19 ◽  
Author(s):  
João Cotas ◽  
Adriana Leandro ◽  
Diana Pacheco ◽  
Ana M. M. Gonçalves ◽  
Leonel Pereira
Keyword(s):  
Fatty Acids ◽  
Scientific Community ◽  
Point Of View ◽  
Red Seaweed ◽  
Bioactive Substances ◽  
Comprehensive Review ◽  
Red Seaweeds ◽  
Therapeutic Applications ◽  
Biomedical Interest ◽  
Advanced Applications

The red seaweed group (Rhodophyta) is one of the phyla of macroalgae, among the groups Phaeophyceae and Chlorophyta, brown and green seaweeds, respectively. Nowadays, all groups of macroalgae are getting the attention of the scientific community due to the bioactive substances they produce. Several macroalgae products have exceptional properties with nutraceutical, pharmacological, and biomedical interest. The main compounds studied are the fatty acids, pigments, phenols, and polysaccharides. Polysaccharides are the most exploited molecules, which are already widely used in various industries and are, presently, entering into more advanced applications from the therapeutic point of view. The focuses of this review are the red seaweeds’ compounds, its proprieties, and its uses. Moreover, this work discusses new possible applications of the compounds of the red seaweeds.

scholarly journals Red Seaweed Pigments from a Biotechnological Perspective

Phycology ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 1-29
Author(s):  
Marta V. Freitas ◽  
Diana Pacheco ◽  
João Cotas ◽  
Teresa Mouga ◽  
Clélia Afonso ◽  
...  
Keyword(s):  
State Of The Art ◽  
Scale Up ◽  
Point Of View ◽  
Red Seaweed ◽  
Biotechnological Applications ◽  
Biotechnological Potential ◽  
Red Seaweeds ◽  
Extraction And Purification ◽  
Blue Economy ◽  
Commercial Applications

Algae taxa are notably diverse regarding pigment diversity and composition, red seaweeds (Rhodophyta) being a valuable source of phycobiliproteins (phycoerythrins, phycocyanin, and allophycocyanin), carotenes (carotenoids and xanthophylls), and chlorophyll a. These pigments have a considerable biotechnological potential, which has been translated into several registered patents and commercial applications. However, challenges remain regarding the optimization and subsequent scale-up of extraction and purification methodologies, especially when considering the quality and quantity needs, from an industrial and commercial point of view. This review aims to provide the state-of-the-art information on each of the aforementioned groups of pigments that can be found within Rhodophyta. An outline of the chemical biodiversity within pigment groups, current extraction and purification methodologies and challenges, and an overview of commercially available products and registered patents, will be provided. Thus, the current biotechnological applications of red seaweeds pigments will be highlighted, from a sustainable and economical perspective, as well as their integration in the Blue Economy.

Using Published Trial Schematics to Assess a Brief (Spatial) History of Time: Questioning the Graphical Depiction of Experimental Procedures

2015 ◽  
Vol 3 (3-4) ◽  
pp. 317-322
Author(s):  
Benjamin J. Dyson
Keyword(s):  
Scientific Community ◽  
Point Of View ◽  
Spatial Representations ◽  
Spatial History ◽  
Spatial Expressions ◽  
History Of ◽  
Temporal Events ◽  
Alternative Routes ◽  
Bottom To Top ◽  
Representation Of Time

Trial schematics are ubiquitous within psychology journals articles and have the potential to inform how we think about time in space from a non-linguistic point of view. Graphical representations of trial schematics were used to compare the spatial representations of time used by the scientific community with the dominant spatial stereotypes for temporal events reported by the scientific community. From 294 observations, approximately 81% of trial schematics contained left-to-right and / or top-to-bottom representations of first-to-last events, consistent with the dominant Western spatial expressions of time. An initially counter-intuitive left-to-right but bottom-to-top spatial stereotype used in approximately 18% of schematics is discussed with respect to its potential perceptual origins. The complications that arise from the use of multiple spatial axes in the representation of time are highlighted and given the tendency for trial schematics to be informationally poor, alternative routes for the supply of thorough experimental detail are suggested.

scholarly journals Carotenoid Profiling of a Red Seaweed Pyropia yezoensis: Insights into Biosynthetic Pathways in the Order Bangiales

Marine Drugs ◽  
2018 ◽  
Vol 16 (11) ◽  
pp. 426 ◽  
Author(s):  
Jiro Koizumi ◽  
Naoki Takatani ◽  
Noritoki Kobayashi ◽  
Koji Mikami ◽  
Kazuo Miyashita ◽  
...  
Keyword(s):  
1H Nmr ◽  
Metabolic Pathways ◽  
Pyropia Yezoensis ◽  
Biosynthetic Pathways ◽  
Red Seaweed ◽  
Red Seaweeds ◽  
Natural Pigments ◽  
Photosynthetic Organisms ◽  
Metabolic Products ◽  
Β Carotene

Carotenoids are natural pigments that contribute to light harvesting and photo-protection in photosynthetic organisms. In this study, we analyzed the carotenoid profiles, including mono-hydroxy and epoxy-carotenoids, in the economically valuable red seaweed Pyropia yezoensis, to clarify the detailed biosynthetic and metabolic pathways in the order Bangiales. P. yezoensis contained lutein, zeaxanthin, α-carotene, and β-carotene, as major carotenoids in both the thallus and conchocelis stages. Monohydroxy intermediate carotenoids for the synthesis of lutein with an ε-ring from α-carotene, α-cryptoxanthin (β,ε-caroten-3’-ol), and zeinoxanthin (β,ε-caroten-3-ol) were identified. In addition, β-cryptoxanthin, an intermediate in zeaxanthin synthesis from β-carotene, was also detected. We also identified lutein-5,6-epoxide and antheraxanthin, which are metabolic products of epoxy conversion from lutein and zeaxanthin, respectively, by LC-MS and 1H-NMR. This is the first report of monohydroxy-carotenoids with an ε-ring and 5,6-epoxy-carotenoids in Bangiales. These results provide new insights into the biosynthetic and metabolic pathways of carotenoids in red seaweeds.

scholarly journals Comparison of Morphological, Antidiabetic and Antioxidant Properties of Goji Fruits

2020 ◽  
Vol 24 (1) ◽  
pp. 1-14
Author(s):  
Arleta Kruczek ◽  
Ireneusz Ochmian ◽  
Marcelina Krupa-Małkiewicz ◽  
Sabina Lachowicz
Keyword(s):  
Antioxidant Activity ◽  
Positive Impact ◽  
Antioxidant Properties ◽  
Total Content ◽  
Point Of View ◽  
Bioactive Substances ◽  
Health Promoting ◽  
Berry Fruits ◽  
North Western ◽  
Nitrite Content

AbstractThere is a growing public interest in fruits labeled as „superfood” (functional food). A “superfood” should have a high content of bioactive substances with a positive impact on human health. Seven different cultivars of goji berry fruits (Lycium chinense Mill.) grown in north-western Poland were evaluated for its physicochemical parameters, antidiabetic and antioxidant activity, and polyphenol content. The length of 1-year-old shoots ranged from 36 cm (‘Big Lifeberry’) to 82 cm (‘Korean Big’). Cultivars from the group of Big were characterized by the biggest fruits (17.3-24.2 mm) with the greatest weight of 100 fruits (96.7­122.1 g). ‘Big Lifeberry’ contained high amounts of L-ascorbic acid (408 mg 1000/g) and provitamin A (190 mg 1000/g) and showed high antidiabetic (α-amylase IC50=33.4 mg/mL; α-glucosidase IC50=9.9 mg/mL) and antioxidant activity (ABTS·+ 6.21 and FRAP 5.58 mmol T/100 g). ‘Big Lifeberry’ was also characterized by a high total content of polyphenols (43.64 mg 100/g). Furthermore, the nitrite content in all the cultivars tested was at a relatively low level. Among the examined cultivars, the most attractive one concerning the consumers’ point of view of the size, weight and high content of health-promoting compounds is ‘Big Lifeberry’.

scholarly journals A Comprehensive Review of the Composition, Nutritional Value, and Functional Properties of Camel Milk Fat

Foods ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2158
Author(s):  
Ibrahim A. Bakry ◽  
Lan Yang ◽  
Mohamed A. Farag ◽  
Sameh A. Korma ◽  
Ibrahim Khalifa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Milk Fat ◽  
Essential Fatty Acids ◽  
Saturated Fatty Acids ◽  
Camel Milk ◽  
Cow Milk ◽  
Comprehensive Review ◽  
Milk Fat Globules ◽  
Health Promoting ◽  
Nutritional Benefits

Recently, camel milk (CM) has been considered as a health-promoting icon due to its medicinal and nutritional benefits. CM fat globule membrane has numerous health-promoting properties, such as anti-adhesion and anti-bacterial properties, which are suitable for people who are allergic to cow’s milk. CM contains milk fat globules with a small size, which accounts for their rapid digestion. Moreover, it also comprises lower amounts of cholesterol and saturated fatty acids concurrent with higher levels of essential fatty acids than cow milk, with an improved lipid profile manifested by reducing cholesterol levels in the blood. In addition, it is rich in phospholipids, especially plasmalogens and sphingomyelin, suggesting that CM fat may meet the daily nutritional requirements of adults and infants. Thus, CM and its dairy products have become more attractive for consumers. In view of this, we performed a comprehensive review of CM fat’s composition and nutritional properties. The overall goal is to increase knowledge related to CM fat characteristics and modify its unfavorable perception. Future studies are expected to be directed toward a better understanding of CM fat, which appears to be promising in the design and formulation of new products with significant health-promoting benefits.

scholarly journals Fatty acids in intramuscular fat of Ile de France lambs in two different production systems

2018 ◽  
Vol 61 (4) ◽  
pp. 395-403
Author(s):  
Milan Margetín ◽  
Marta Oravcová ◽  
Jana Margetínová ◽  
Róbert Kubinec
Keyword(s):  
Fatty Acids ◽  
Gas Chromatography ◽  
Linoleic Acid ◽  
Production System ◽  
Production Systems ◽  
Intramuscular Fat ◽  
Point Of View ◽  
Longissimus Dorsi ◽  
Fa Composition ◽  
Long Chain

Abstract. The fatty acid (FA) composition in the intramuscular fat (IMF) of the musculus longissimus dorsi (MLD) of Ile de France purebred lambs in two different production systems in Slovakia was evaluated using gas chromatography. In the first production system, lambs and ewes were assigned to pasture without access to concentrates (P). In the second system, lambs and ewes were confined indoors with hay/silage and access to concentrates (S). An analysis of variance with the following factors was employed: production system, sex, and production system–sex interactions. The proportions of arachidonic, eicosapentaeonic, docosapentaeonic, and docosahexaenoic FAs, i.e. long-chain polyunsaturated FA (PUFA), were significantly higher in P lambs (1.83, 0.82, 0.92, 0.29 g 100 g−1 FAME, respectively) than in S lambs (0.45, 0.14, 0.30, 0.09 g 100 g−1 FAME, respectively). The proportions of conjugated linoleic acid (CLA), n-6 PUFA, n-3 PUFA, and essential FA (linoleic and α-linolenic) were also significantly higher in P lambs (2.10, 8.50, 4.55, and 8.80 g 100 g−1 FAME, respectively) than in S lambs (0.65, 3.27, 1.50, and 3.64 g 100 g−1 FAME, respectively). The proportions of palmitic acid and myristic acid as important individual saturated FAs (SFA) were significantly higher in S lambs (28.51 and 8.30 g 100 g−1 FAME, respectively) than in P lambs (21.80 and 5.63 g 100 g−1 FAME, respectively). The proportion of all SFAs was also significantly higher in S lambs (57.87 g 100 g−1 FAME) than in P lambs (48.70 g 100 g−1 FAME). From a nutrition and human health point of view (i.e. higher proportions of PUFA, CLA, and essential FAs and lower proportions of SFAs), meat from P lambs was found to be more favourable and would be more highly recommended for consumption.

scholarly journals Aurones: A Golden Resource for Active Compounds

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 2
Author(s):  
Ilaria Mazziotti ◽  
Giovanni Petrarolo ◽  
Concettina La Motta
Keyword(s):  
Functional Properties ◽  
Scientific Community ◽  
Recent Literature ◽  
Biological Pathways ◽  
Point Of View ◽  
Drug Candidates ◽  
The Past ◽  
Comprehensive Picture ◽  
Functional Point ◽  
Chemical Strategies

Deemed as poorly represented in nature, aurones have been often overlooked by researchers compared to other members of the flavonoid superfamily. However, over the past two decades, they have been reassessed by the scientific community, who are increasingly appreciating their ability to modulate several biological pathways. This review summarizes the recent literature on this class of compounds, which has been analyzed from both a chemical and a functional point of view. Original articles, reviews and editorials featured in Pubmed and Scifinder over the last twenty years have been taken into account to provide the readers with a view of the chemical strategies to obtain them, their functional properties, and their potential of technological use. The resulting comprehensive picture aims at raising the awareness of these natural derivatives as effective drug candidates, fostering the development of novel synthetic analogues.

scholarly journals CONVENTIONAL AND CONSENSUAL CONCEPTIONS OF SCIENTIFIC KNOWLEDGE NATURE

2020 ◽  
pp. 7-26
Author(s):  
Сергей Александрович Лебедев ◽  
Сергей Николаевич Коськов
Keyword(s):  
Scientific Knowledge ◽  
Scientific Community ◽  
A Priori ◽  
Scientific Work ◽  
Point Of View ◽  
Main Subject ◽  
Pure Experience ◽  
Classical Philosophy ◽  
The One ◽  
Methodology Of Science

В статье излагается содержание двух базовых концепций неклассической философии и методологии науки: конвенционалистской и консенсуалистской теории природы научного знания и научной истины. Каждая из них является альтернативой двум основным парадигмам классической философии и методологии науки: эмпиризму (позитивизму) и рационализму. С точки зрения конвенционализма научное знание не есть ни описание чистого опыта, ни его обобщение. Но оно не является также и результатом некой априорной интуиции и чистого разума. Согласно конвенционализму научное знание - это система доказательной информации, исходные принципы которой имеют характер условных, конвенциональных истин. Отсюда следует, что любая истина в науке не категорична, а условна и имеет форму «если, то». Консенсуалистская концепция природы научного знания возникла в философии науки второй половины XX в. Она была, с одной стороны, обобщением конвенционализма, а с другой - его отрицанием. Если в конвенционализме основным субъектом научного познания является отдельный ученый, то в консенсуалистской эпистемологии таким субъектом является социальный субъект - научное сообщество. Научное познание имеет принципиально коллективный характер как в плане его получения в силу разделения научного труда, так и в плане его легитимации и оценки. Последние операции всегда являются результатом консенсуса научного сообщества. The article examines the content of two basic conceptions of non-classical philosophy and methodology of science: the conventionalist and consensual theory of the nature of scientific knowledge. Each of them is an alternative to the two main paradigms of classical philosophy and the methodology of science: empiricism (positivism) and rationalism. From the point of view of conventionalism, scientific knowledge is neither a description of pure experience nor a generalization of it. But it is also not the result of some a priori intuition and pure reason. According to conventionalism, scientific knowledge is a system of evidence-based information, the initial principles of which have the character of conditional, conventional truths. It follows that any truth in science is not categorical, but conditional and has the form «if, then». The consensual concept of the nature of scientific knowledge emerged in the philosophy of science of the second half of the twentieth century. It was, on the one hand, a generalization of conventionalism; on the other, a negation of it. If in conventionalism the main subject of scientific knowledge is an individual scientist, then in consensual epistemology such a subject is a social subject - the scientific community. Scientific knowledge has a fundamentally collective character, both in terms of its acquisition by virtue of the division of scientific work, and in terms of its legitimization and evaluation. The latest operations are always the result of a consensus of the scientific community.

Smart Mesoporous Nanomaterials With Improved Therapeutic Applications

2018 ◽  
pp. 431-447 ◽  
Author(s):  
Sandhya Sanand ◽  
Anshika Tyagi ◽  
Sandeep Kumar ◽  
Gautam Kaul
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Surface Modifications ◽  
Chemotherapeutic Agents ◽  
Point Of View ◽  
Site Specific ◽  
Comprehensive Review ◽  
Post Synthesis ◽  
New Generation ◽  
Toxic Drugs

Nanomaterials have revolutionized the drug delivery and therapeutic industry due to their unique physical characteristics, which render them extremely manipulative at nano-scale. One such category of nanomaterials is mesoporous silica nanoparticles. Due to their small size and rigid honeycomb-like structure, they are highly conducive for packaging of drugs, dyes, antibodies, etc. In addition, they show excellent biocompatibility. These new generation nanomaterials can be further functionalized by incorporating surface modifications, thus increasing their acceptability as carriers for drugs and molecules. In this chapter, a brief and comprehensive review covering various aspects of the recent advancements in synthesis of mesoporous nanomaterials and post-synthesis strategies for functionalization has been presented. Further, it also sheds light on how efficiently these smart nano-carriers are involved in transport and site-specific delivery of highly toxic drugs, like chemotherapeutic agents for cancer treatment, and their biocompatibility evaluation from a biosafety point of view.

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