Link Between Anhedonia and Depression During Early Alcohol Abstinence: Gender Matters

2019 ◽  
Vol 55 (1) ◽  
pp. 71-77 ◽  
Author(s):  
G Petit ◽  
G Deschietere ◽  
G Loas ◽  
O Luminet ◽  
P de Timary

Abstract Aims The aim of the present study was to evaluate the relation between anhedonia and depression in alcohol use disorders (AUD) during detoxification: Is trait anhedonia measured at the beginning of detoxification predictive of depressive symptoms observed at the end? Does state anhedonia recover during detoxification as depression does? Gender differences that have been previously observed for depression in AUD were also explored. Methods 81 AUD inpatients were tested at T1 (day 1) and T2 (day 14–18) of withdrawal with the trait Physical Anhedonia Scale, the state anhedonia Snaith–Hamilton Pleasure Scale, the Beck depression inventory and the Spielberger State Anxiety Inventory and compared to 34 control participants, matched for age and gender. Results AUD patients scored significantly higher than controls on depression, anxiety and state and trait anhedonia when they just entered the detoxification unit. Depression, anxiety and state anhedonia decreased between T1 and T2 in AUD patients. In women, state anhedonia at T1 was predictive of depressive symptoms at T2 over and above anxiety and depression at T1. Conclusion In AUD, state anhedonia recovers during detoxification, concurrently to other affective-related symptoms. However, in women, trait anhedonia predicts the level of depression at the end of detoxification, above and beyond anxiety. This finding stresses the importance of addressing anhedonia in the treatment of AUD and emphasizes the need for targeted interventions within clinical settings in this gender. Clinical consequences are discussed.

Author(s):  
Éva Kállay ◽  
Alexandra Rebeca Mihoc

"The changes occurring in modern society can significantly influence individuals’ well-being, mental health and even personality traits such as narcissism and perfectionism. Since studies investigating age and gender differences in narcissism and perfectionism have produced mixed results, and the number of studies conducted in Romanian population is scarce, the main aims of this study were to investigate possible age and gender differences in narcissism, perfectionism and several mental-health indicators in a sample of healthy participants, as well as specific association patterns between these variables within each group of participants. Our sample included 465 millennials and 149 participants over 35 years of age. The results indicate that millennials reported significantly lower levels of narcissism and self-oriented perfectionism than the older generations, higher levels of depressive symptoms and lower levels of autonomy, environmental mastery, purpose in life, and self-acceptance. Female millennials reported lower levels of narcissistic traits and higher levels of socially-prescribed perfectionism, depressive symptoms, personal growth, and positive relations with others than male participants. Older females indicated significantly higher levels of depressive symptoms and loneliness than male participants. Regarding association patterns, in the group of millennial women narcissism was positively correlated with self-oriented, socially-prescribed perfectionism and subjective well-being, and negatively with loneliness, environmental mastery and purpose in life. In millennial males, we found significant positive correlations only between narcissism and subjective well-being and environmental mastery. Our findings may have important implications for the literature regarding millennials and can contribute to the interventions and prevention programs designed to improve their well-being. Keywords: millennials, narcissism, perfectionism, mental health indicators, age and gender differences "


2021 ◽  
Vol 12 ◽  
Author(s):  
Natacha Forthoffer ◽  
Alexis Tarrada ◽  
Hélène Brissart ◽  
Louis Maillard ◽  
Coraline Hingray

Purpose: Anxiety and depression are highly prevalent in patients with epilepsy (PWE), and these symptoms can even precede the onset of the pathology. We aimed to define the prevalence of anxiety and depressive symptoms at the time of the epilepsy diagnosis and the factors related to their presence in newly diagnosed adult patients.Methods: One hundred and twelve newly diagnosed patients were assessed, usually in the week after diagnosis. Patients were untreated at this time. We used the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E, cut-off ≥15) and the Generalized Anxiety Disorder 7-Item scale (GAD-7, cut-off >7). A semi-structured interview was conducted to collect sociodemographic and epilepsy data and patients' psychiatric history. We first compared patients with and without anxiety symptoms, then patients with and without depressive symptoms.Results: According to the GAD-7 scale, the prevalence of anxiety symptoms at the time of diagnosis was 35%. Patients with anxiety symptoms had significantly more psychiatric history (26%, p = 0.001) and more history of psychological trauma (51%, p = 0.003) than patients with no anxiety symptoms. According to the NDDI-E scores, the prevalence of depressive symptoms at the time of the diagnosis was 11%. Patients with depressive symptoms had significantly more psychiatric history (43%, p < 0.001) and more history of psychological trauma (65%, p = 0.007) than patients with no depressive symptoms. No difference between groups was found for other sociodemographic variables (age and gender), epilepsy characteristics (number of seizures prior to diagnosis, time from first seizure to diagnosis, type of epilepsy, and localization in focal epilepsy), or neurological comorbidities.Conclusions: Anxiety symptoms are common whereas depressive symptoms are less prevalent at the time of diagnosis. It appears essential to be aware of anxiety and depression in newly diagnosed epileptic patients. They should be screened and routinely monitored, especially those patients with a history of psychological trauma and/or psychiatric disorders. Longitudinal follow-up is required to identify whether these factors and anxiety and depression themselves have an impact on the future course of care.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Wei Liao ◽  
Zhicheng Luo ◽  
Yitan Hou ◽  
Ningning Cui ◽  
Xiaotian Liu ◽  
...  

Abstract Background This is a cross-sectional study to explore the age and gender specific association between obesity and depression in Chinese rural adults. Methods A total of 29,900 eligible participants from the Henan Rural Cohort Study were included. Standard anthropometric measurements were undertaken to obtain data on body mass index (BMI) and waist circumference (WC). The Patient Health Questionnaire-2 (PHQ-2) was utilized to discover depressive symptoms. Logistic regression was performed to explore the association between obesity (independent variable) and depressive symptoms (dependent variable). Results There were 1777 subjects with depressive symptoms, accounting for 5.94%. After multivariable adjustment, compared with normal weight group, the odds ratios (ORs) [95% confidence interval (CI)] for depressive symptoms in underweight, overweight and general obese groups were 1.41 (1.08–1.84), 0.87 (0.78–0.97) and 0.86 (0.74–0.99), respectively. Similarly, the OR (95% CI) of abdominal obesity group was 0.84 (0.76–0.93). Besides, there was linear decreasing trend of WC with depressive symptoms, but not BMI. Moreover, the inverse association between obesity and depressive symptoms was stronger in men and the elderly than that in women and the young. Conclusion Underweight was associated with a higher prevalence of depressive symptoms, which indicated that health care should pay attention to underweight as well as obesity, especially for women and the young. Clinical trial registration The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 2015-07-06.


2002 ◽  
Vol 24 (2) ◽  
pp. 63-67 ◽  
Author(s):  
Saint-Clair Bahls

OBJECTIVES: To assess, using the self-report questionnaire Children's Depression Inventory (CDI), the rate of depressive symptoms and its distribution by age and gender, in a sample of students. METHODS: Application of the CDI in 463 students, aged 10 to 17. RESULTS: The total mean score was 13.0 with a standard deviation of 7.0 (median = 12.0), for females the score was 14.4 with a standard deviation of 7.2 (median = 13.0) and for males it was 11.1 with a standard deviation of 6.2 (median = 10.0). Using the cut-off score of 19, 20.3% of the students had important indications of depressive symptoms. The age factor had no significance; however, there was a non-significant trend of increasing rates of depressive symptoms in the ages of 10 to 15 and a decreasing trend in the ages of 16 to 17. There was a statistically significant predominance of females above the cut-off score compared to males (72.3% versus 27.7%), with a ratio of 2.6 females for each male. CONCLUSIONS: These results suggest that adolescent students have a high level of depressive symptoms, with a clear predominance of females over males, and a probable period of onset concentrated between the ages of 12 and 15 years.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Philippe A. Melas ◽  
Malin Wirf ◽  
Helder André ◽  
Nitya Jayaram-Lindström ◽  
Aleksander A. Mathé ◽  
...  

AbstractAlcohol use disorders (AUD) often co-occur with anxiety and depressive disorders, and anxiety often drives relapse during alcohol abstinence. Optimal AUD pharmacotherapies may thus need to target both excessive alcohol intake and elevated anxiety. (−)-OSU6162 (OSU) is a monoamine stabilizer that attenuates alcohol-mediated behaviors in both preclinical and clinical settings. However, OSU’s effect on anxiety-like behavior following long-term drinking remains unknown. To this end, we utilized a genetic rat model that exhibits increased anxiety- and depression-like behaviors (Flinders Sensitive Line; FSL) and their controls (Flinders Resistant Line; FRL). Using the novelty suppressed feeding (NSF) test, we evaluated anxiety-like behaviors (1) at baseline, (2) following long-term voluntary drinking and after 24 h of alcohol deprivation, and (3) following OSU administration in the same animals. At baseline, FSL animals displayed significantly elevated anxiety-like characteristics compared to FRL. Compared to alcohol-naïve animals, long-term drinking significantly reduced anxiety-like behaviors in FSL, without any significant effects in FRL animals. Compared to vehicle, OSU administration significantly reduced anxiety-like behaviors in alcohol-naïve FSL and long-term drinking FRL animals. While there was no significant difference in alcohol intake between FSL and FRL, OSU attenuated alcohol intake in both strains. Conclusively, in addition to the compound’s previously identified ability to suppress alcohol-mediated behaviors, OSU may also possess anxiolytic properties, warranting further clinical evaluation in both AUD and anxiety disorder settings.


2012 ◽  
Vol 7 (1) ◽  
pp. 26 ◽  
Author(s):  
Carlos Montero Carretero ◽  
Juan A. Moreno-Murcia ◽  
Inmaculada González Ponce ◽  
Juan J. Pulido González ◽  
Eduardo M. Cervelló Gimeno

<p><strong><em>Aim</em></strong><strong>:</strong> The objective of this study was to analyze the psychometric properties of the Competitive State Anxiety Inventory-2 (CSAI-2) in Spanish judokas, and calculate differences in pre-competitive state anxiety due the sport level, age and gender. We analyze these relationships using a multidimensional anxiety perspective.</p><p><strong><em>Method: </em></strong>A sample of 128 judokas from amateur to high performance level participated in our study. The intensity and directional somatic anxiety, cognitive anxiety and self confidence of the CSAI-2 were measured.</p><strong><em>Results:</em></strong> The results show that the questionnaire administered showed acceptable psychometric properties, and there are differences in directional somatic and cognitive anxiety for age, and in intensity self confidence for sport level. The implications of these findings for the process of training and competition are discussed in the document.


2018 ◽  
Vol 17 (5) ◽  
pp. 311-327
Author(s):  
Gretchen Kurdziel ◽  
Leticia Y. Flores ◽  
Jenny Macfie

Adolescence is a time of significant change with social, cognitive, and emotional alternations, and growth of autonomy and identity. This is a single clinical case study that uses long-term psychodynamic psychotherapy with an adolescent female diagnosed with comorbid social anxiety and persistent depression. The treatment initially focused on addressing the patient’s self-esteem, perfectionism, and self-criticism. During the treatment it was revealed that the patient’s sexual and gender identity contributed to social anxiety and depressive symptoms, and the therapy conceptualized the role of these identities as contributing to social discomfort which perpetuated her depressive symptoms. Through accepting her budding sexual and gender identity, the patient successfully became more comfortable in social settings which ultimately alleviated her depressive symptoms. This treatment highlights the unique nature of working with an adolescent apart of the sexual and gender minority, and how these identities contributed to her experience of social anxiety and depression.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 985-985
Author(s):  
Betul Urganci

Abstract A growing body of research suggests that greater perceived partner responsiveness- the extent to which individuals feel cared for, understood, and validated by their romantic partner- leads to longer, healthier, and happier life in adulthood, yet little is known about possible moderating factors between responsiveness and well-being. Using a longitudinal design, the current study tested the moderating roles of age and gender in association between perceived partner responsiveness and depression symptoms. The data for the present study came from the National Survey of Midlife in the United States (MIDUS I and II) which is a longitudinal study on health and aging. A life span sample of 2856 married or cohabiting individuals (1402 Female, Mage= 47.16) completed measures of perceived partner responsiveness, depression, age, and gender in two waves (T1 and T2). The results showed that greater perceived partner responsiveness at T1 predicted lower depressive symptoms at T2 controlling for depressive symptoms at T1. This finding remained when controlling for potential confounders including demographics and health covariates. The moderation analysis demonstrated that participants’ age was not a significant moderator in the association between perceived partner responsiveness and depression. Yet, gender significantly was a significant moderator such that the association of perceived partner responsiveness and depression was significant for female but not for male participants. These findings can have implications for mental health and relational well-being.


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