scholarly journals Ketogenic Diet Against Liver Tumor

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 338-338
Author(s):  
Jacquelyne Motta ◽  
Luciano Lobo ◽  
Donadao Fabiola
Keyword(s):  
Blood Glucose ◽  
Side Effects ◽  
Ketogenic Diet ◽  
Liver Tumor ◽  
Case Reports ◽  
The Body ◽  
Ultrasound Images ◽  
Alternative Source ◽  
Glucose Levels ◽  
Funding Sources

Abstract Objectives Report my experience in treating two liver tumor patients with ketogenic diet KD protocol as monotherapy. In addition to the two patients who enrolled in this study, I also reviewed findings from 10 other patients, including 2 patients from case reports. Methods The ketogenic diet consists of high fat foods, foods that contain an adequate amount of protein, and a very low amount of carbohydrates. Normally, the body gets its main source of energy (sugar) from carbs. However, the ketogenic diet deprives the body of glucose, inducing a state of “ketosis.” During ketosis, the body is forced to break down stored fat instead of sugar to produce an alternative source of energy. Results The two patients who enrolled in my KD pilot study were monitored with twice daily measurements of blood glucose and ketones. Within 30 days of initiating the KD blood glucose levels declined to low-normal levels and blood ketones were elevated. Results of ultrasound images indicated that tumors has gone 1 year after KD. One patient exhibited significant clinical improvements during the study. All of these patients was treated using KD as monotherapy. No major side effects due to KD have been reported in any of these patients. They continued the ketogenic diet remaining free of disease progression. Conclusions I conclude that: 1. KD is safe and without major side effects; 2. ketosis can be induced using customary foods; 3. treatment with KD may be effective in controlling the progression of some liver cancer cells; 4. Maybe we can manipulate our own biological system a little bit or activate something we already have in place in order to more effectively combat cancer. Funding Sources DoTerra Science.

Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat

MEDISAINS ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 19
Author(s):  
Fairuz Fairuz ◽  
Hasna Dewi ◽  
Humaryanto Humaryanto
Keyword(s):  
Blood Glucose ◽  
Side Effects ◽  
Type I Diabetes ◽  
Langerhans Cell ◽  
Diabetic Rat ◽  
Type I ◽  
Antidiabetic Effect ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results:  A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.

scholarly journals Non-Invasive Determination of Blood Glucose Levels by Optical Waveguide

2021 ◽  
Author(s):  
Mohsen Askarbioki ◽  
Mojtaba Mortazavi ◽  
Abdolhamid Amooee ◽  
Saeid Kargar ◽  
Mohammad Afkhami-Ardekani ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Optical Waveguide ◽  
Interstitial Fluid ◽  
Evanescent Waves ◽  
The Body ◽  
Statistical Population ◽  
Glucose Levels ◽  
Non Invasive ◽  
Blood Glucose Levels

Objective: Today, there are various non-invasive techniques available for the determination of blood glucose levels. In this study, the level of blood glucose was determined by developing a new device using near-infrared (NIR) wavelength, glass optical waveguide, and the phenomenon of evanescent waves. Materials and Methods: The body's interstitial fluid has made possible the development of new technology to measure the blood glucose. As a result of contacting the fingertip with the body of the borehole rod, where electromagnetic waves are reflected inside, evanescent waves penetrate from the borehole into the skin and are absorbed by the interstitial fluid. The electromagnetic wave rate absorption at the end of the borehole rod is investigated using a detection photodetector, and its relationship to the people's actual blood glucose level. Following precise optimization and design of the glucose monitoring device, a statistical population of 100 participants with a maximum blood glucose concentration of 200 mg/dL was chosen. Before measurements, participants put their index finger for 30 seconds on the device. Results: According to this experimental study, the values measured by the innovative device with Clark grid analysis were clinically acceptable in scales A and B. The Adjusted Coefficient of Determination of the data was estimated to be 0.9064. Conclusion: For future investigations, researchers are recommended to work with a larger statistical population and use error reduction trends to improve the accuracy and expand the range of measurements.

scholarly journals Euglycemic Diabetic Ketoacidosis in Pregnancy: A Case Report and Review of Current Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Johnny F. Jaber ◽  
Matthew Standley ◽  
Raju Reddy
Keyword(s):  
Blood Glucose ◽  
Diabetic Ketoacidosis ◽  
Case Reports ◽  
Anion Gap ◽  
Fetal Mortality ◽  
Glucose Levels ◽  
Elevated Glucose ◽  
High Doses ◽  
Euglycemic Diabetic Ketoacidosis ◽  
In Pregnancy

Diabetic ketoacidosis (DKA) in pregnancy is associated with high fetal mortality rates. A small percentage of DKA occurs in the absence of high glucose levels seen in traditional DKA. Prompt recognition and management is crucial. We report a case of a 30-year-old pregnant woman with type 1 diabetes mellitus admitted with euglycemic DKA (blood glucose <200 mg/dL). Initial laboratory testing revealed a severe anion gap acidosis with pH 7.11, anion gap 23, elevated β-hydroxybutyric acid of 9.60 mmol/L, and a blood glucose of 183 mg/dL—surprisingly low given her severe acidosis. The ketoacidosis persisted despite high doses of glucose and insulin infusions. Due to nonresolving acidosis, her hospital course was complicated by spontaneous intrauterine fetal demise. Euglycemia and severe acidosis continued to persist until delivery of fetus and placenta occurred. It was observed that the insulin sensitivity dramatically increased after delivery of fetus and placenta leading to rapid correction of ketoacidosis. This case highlights that severe ketonemia can occur despite the absence of severely elevated glucose levels. We discuss the mechanism that leads to this pathophysiologic state and summarize previously published case reports about euglycemic DKA in pregnancy.

Risperidone in the treatment of psychoses in the elderly: a case report series

2002 ◽  
Vol 17 (2) ◽  
pp. 96-103 ◽  
Author(s):  
R. Bullock ◽  
S. Libretto
Keyword(s):  
Side Effects ◽  
Elderly Patients ◽  
Negative Symptoms ◽  
Case Reports ◽  
Antipsychotic Agents ◽  
The Elderly ◽  
The Body ◽  
Continuous Treatment ◽  
Atypical Antipsychotic Agents

SummaryRisperidone is one of the newer atypical antipsychotic agents, which combines potent serotonin and dopamine receptor antagonism. It shows efficacy against the positive and negative symptoms of schizophrenic psychoses and other psychotic conditions, and has a low propensity to cause extrapyramidal side effects. The aim of these case reports in elderly patients is to provide the benefit of personal experience with risperidone to the body of published literature and to demonstrate the types of patients that may benefit from treatment. These cases were compiled retrospectively from data collected on referral and during routine hospital appointments. This series covers four main areas of concern when treating the elderly: low-maintenance dosing minimising the likelihood of adverse events; successful treatment of patients previously uncontrolled and experiencing side effects with other antipsychotics; the possibility of intermittent rather than continuous treatment; and the benefits to patients, carers and the health services. At low doses, risperidone is an effective and well-tolerated treatment for psychoses in elderly patients that improves the quality of life for both patients and their caregivers.

scholarly journals Assessment of Blood Glucose and Electrolytes during Cardiopulmonary Bypass in Diabetic and Non-Diabetic Patients of Pakistan

2016 ◽  
Vol 8 (9) ◽  
pp. 159
Author(s):  
Muhammad Bilal ◽  
Abdul Haseeb ◽  
Mohammad Hassaan Khan ◽  
Akash Khetpal ◽  
Muhammad Saad ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Cardiopulmonary Bypass ◽  
Repeated Measures ◽  
Artery Bypass ◽  
The Body ◽  
Diabetic Patients ◽  
Blood Electrolytes ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

<p><strong>INTRODUCTION: </strong>Perioperative hyperglycemia has been shown to be related to higher levels of morbidity and mortality in patients on cardiopulmonary bypass (CPB) undergoing coronary artery bypass grafting (CABG), both diabetic and non-diabetic. Blood electrolytes, like sodium, potassium, calcium, and chloride play a very important role in the normal functioning of the body and can lead to a variety of clinical disorders if they become deficient. A minimal number of studies have been conducted on the simultaneous perioperative changes in both blood glucose and electrolyte levels during CPB in Pakistan. Therefore, our aim is to record and compare the changes in blood glucose and electrolyte levels during CPB in diabetic and non-diabetic patients.</p><p><strong>MATERIALS &amp; METHODS: </strong>This was a prospective, observational study conducted on 200 patients who underwent CABG with CPB, from October 2014 to March 2015. The patients were recruited from the Cardiac Surgery Ward, Civil Hospital Karachi after they complied with the inclusion criteria. Repeated-measures analysis of variance (ANOVA) was used to compare the trend of the changes perioperatively for the two groups.</p><p><strong>RESULTS: </strong>There was no significant difference in changes in blood glucose between the two groups (<em>P</em> = 0.62). The only significant difference detected between the two groups was for PaCO<sub>2</sub> (<em>P</em> = 0.001). Besides, further analysis revealed insignificant group differences for the trend changes in other blood electrolytes (<em>P</em> &gt; 0.05).</p><p><strong>CONCLUSION: </strong>Our findings highlighted that there is no significant difference in blood electrolytes changes and the increase in blood glucose levels between diabetic and non-diabetic patients.</p>

scholarly journals Aktivitas Antidiabetes Ekstrak Air-Etanol, n-Heksan, dan Etil Asetat Uwi Banggai (Dioscorea alata L.) Dengan Metode Induksi Aloksan Pada Mencit Jantan (Mus musculus)

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Khildah Khaerati ◽  
Delina Amini ◽  
Ihwan
Keyword(s):  
Blood Glucose ◽  
Ethyl Acetate ◽  
Ethyl Acetate Extract ◽  
Test Preparation ◽  
The Body ◽  
Hexane Extract ◽  
Dioscorea Alata ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Ethyl Acetate Extracts

Hyperglycemia is a condition of increased blood glucose levels caused by insufficient insulin enzymes produced to control blood sugar levels in the body. This study aimed to determine the activity of ethanol-water, nhexane, and ethyl acetate extracts of Dioscorea alata L. in reducing blood  glucose levels in hyperglycemia modeled mice that were given intraperitoneal alloxan induction. 25 white rats were divided into 5 groups of test animals. Each group consists of 5 mice. The first group was given 0.5% sodium carboxymethylcellulose solution as a placebo, the second group was given 0.65 mg/kg BW glibenclamide as a positive comparison group, the third group was given the suspension of ethanol-water extract, the fourth group was given n-hexane extract, and the fifth group was given ethyl acetate extract at a dose of 140 mg/kg BW. The test preparation was orally given within 14 days of testing. The test was measured as the initial blood glucose levels of mice after alloxan induction and after giving the test preparation suspension. The results of the qualitative analysis illustrate that the water-ethanol extract can reduce blood glucose levels by 31.39%, n-hexane extract by 51.11%, and ethyl acetate extract by 50.77%. The results of quantitative analysis using One Way ANOVA method showed that the water-ethanol, n-hexane, and ethyl acetate extracts significantly decreased the blood glucose levels of mice. The best antidiabetic activity was ethyl acetate extract with a decrease in rat blood glucose levels by 169 mg/kg BW.

scholarly journals GIVING RED RICE (ORIZA NIVARA) TO CHANGE GLUCOSE LEVELS IN DIABETES MELLITUS PATIENTS IN KENDARI CITY

2021 ◽  
Vol 3 (1) ◽  
pp. 38-44
Author(s):  
La Ode Ardiansyah ◽  
Nawawi Nawawi
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Brown Rice ◽  
Secondary Data ◽  
The Body ◽  
P Value ◽  
Red Rice ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Quasi Experimental

Background:Diabetes mellitus (DM) is a phenomenon which the body  cannot  produce insulin supply which is indicated by increasing blood glucose levels. Red Rice (Oriza nivara) contains flavonoid compounds which have antidiabetic abilities. It can  reduce blood glucose by increasing insulin secretion and preventing insulin resistance. This study aims to determine the effect of giving brown rice (Oriza nivara) to change   blood glucose levels in people with diabetes mellitus in Kendari City. Methods: This research method was carried out with a quasi-experimental design with pre-post test design for 1 week with primary and secondary data collection techniques. The respondents  were  determined by proportional random sampling. Respondents in this study were 33 people with DM. Result:The results of the study on checking blood glucose levels before and after giving brown rice (oriza nivara) within 1 week obtained P value = 0.000 <  alpha 0.05. Conclusion: there is a  significant  effect of giving brown rice (oriza nivara) on changes in blood glucose level in diabetes mellitus people  in Kendari City.

scholarly journals Blood glucose regulating hormones and their physiological and biochemical roles

2020 ◽  
pp. 44-49
Author(s):  
Maqsuduulah Mujtahid
Keyword(s):  
Nervous System ◽  
Blood Glucose ◽  
Normal Level ◽  
Endocrine System ◽  
The Body ◽  
Regulatory Mechanisms ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Multicellular Organisms ◽  
Physiological And Biochemical

Regulation and coordination of different body organs is important in multicellular organisms. Hormones and the nervous system participate in this synchronization. Hormones are the compounds and chemical messengers produced by cells, glands, or special tissues called the endocrine system and released into the bloodstream. In addition to the hormones, blood is consist of proteins, sugars, lipids, vitamins, etc. Blood sugar is glucose which produces energy in the body. Regular blood glucose levels vary at different ages and exceed 120-170 mg / dl. It is harmful and even fatal to increase or decrease it from the normal level, so the concentration of glucose dissolved in plasma was subject to tight regulation and various regulatory mechanisms were developed thereon. Hormones cortisol, glucagon, adrenaline, and glucocorticoids are the major regulators. These substances are tracked regularly to prevent blood glucose from rising and dropping. Insulin consists of hyperglycemia, as well as other hormones. The mechanism by which it affects the metabolism of the food (carbohydrates, lipids, proteins) prevents hypoglycemia in several respects.

scholarly journals PENGARUH ZUMBA TERHADAP KADAR GULA DARAH

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Novia P. I. Benaino ◽  
S. H. R. Ticoalu ◽  
Djon Wongkar
Keyword(s):  
Blood Glucose ◽  
Glucose Level ◽  
Physical Activities ◽  
T Test ◽  
The Body ◽  
Paired Sample ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test ◽  
Hands And Feet

Abstract: Glucose is the result of carbohydrate metabolism that is converted and absorbed by bloodstream and placed to several organs and body tissues that functions as the main source of energy for muscles, physical activities of the body, central nervous system and brain work. A normal glucose level value is maintained by the body in a narrow range which is about 70-120 mg/dl. Glucose that has formed in its use as an energy source requires physical activities and insulin to stimulate permeability of the fiber muscle. This research aims at finding the effect of zumba to the blood glucose levels. Method: This research is an experiment with a one group pre and post test design that fulfill the criteria such as normal body mass index (18,5-22,9), people with no exercise routine, no diabetes mellitus, no asthma, no heart disease, no broken bones on hands and feet, and not being injured in muscle joints. The research samples are twenty students of nursing program study batch 2013, Faculty of Medicine, Sam Ratulangi University. the blood glucose level is measured before and after zumba exercise. The data are analyzed by Paired Sample-T test using SPSS. Conclusion: Based on the research done on the twenty research subjects, the result shows that there is no significant change of blood glucose levels after the two-week zumba exercise. Keywords: zumba, blood glucose.     Abstrak: Gula darah adalah hasil metabolisme karbohidrat yang terkonversi kemudian terabsorbsi oleh aliran darah dan ditempatkan ke berbagai organ dan jaringan tubuh dengan fungsi sebagai sumber energi utama bagi otot, aktivitas fisik tubuh, sistem saraf pusat dan kerja otak. Nilai kadar glukosa normal dipertahankan oleh tubuh dalam suatu rentangan nilai yang sempit yaitu sekitar 70-120 mg/dl. Glukosa yang telah terbentuk dalam penggunaannya sebagai sumber energi memerlukan aktivitas fisik dan kerja insulin untuk merangsang permebealitas dari serabut otot.Penelitian ini bertujuan untuk mengetahui pengaruh zumba terhadap kadar gula darah. Metode: Penelitian ini bersifat eksperimental dengan rancangan one group pre and post test yang memenuhi kriteria-kriteria yaitu tidak rutin berolahraga, IMT normal (18,5-22,9), bukan penderita penyakit diabetes melitus, bukan penderita penyakit asma, bukan penderita penyakit jantung, bukan penderita patah tulang pada kaki dan tangan, tidak sedang mengalami cedera otot dan sendi. Sampel penelitian yaitu mahasiswi Program Studi Ilmu Keperawatan Fakultas Kedokteran angkatan 2013 Universitas Sam Ratulangi Manado yang berjumlah 20 orang. Kadar gula darah diperiksa sebelum dan sesudah zumba. Data dianalisis dengan Paired Sample T-test menggunakan SPSS. Simpulan: Berdasarkan penelitian yang telah dilakukan pada subjek penelitian diperoleh hasil yaitu tidak terjadi perubahan kadar gula darah yang bermakna setelah melakukan zumba selama dua minggu. Kata kunci: zumba, gula darah.

scholarly journals Body mass index and glucose variations during the night in free-ranging Artibeus planirostris (Chiroptera: Phyllostomidae)

2019 ◽  
Vol 36 ◽  
pp. 1-8 ◽  
Author(s):  
Luane Maria Melo Azeredo ◽  
Monique Silva Ximenes ◽  
Kleytone Alves Pereira ◽  
Maria Paula Aguiar Fracasso ◽  
Luiz Carlos Serramo Lopez
Keyword(s):  
Blood Glucose ◽  
Body Mass ◽  
Body Condition ◽  
The Body ◽  
Energy Reserve ◽  
Glucose Levels ◽  
Reproductive Phase ◽  
Condition Indices ◽  
Positive Correlations ◽  
Free Ranging

Body condition is an important measure to estimate the energy reserve of an organism. Scientists frequently use body condition indices (BCIs) with morphometric measures but direct measurements, such as blood glucose, seem to be more reliable. We observed oscillations in the body condition and glucose indexes of individuals of Artibeusplanirostris (Spix, 1823) during 13 nights in the field. We assume that if glucose levels are proportional to feeding state and body condition is a measure of energy reserve, blood glucose and BCI should be positively correlated and both are expected to increase during the night as the bats leave their diurnal roost to feed. To test this, we examined the relationship between blood glucose levels, BCI and reproductive phase of free flying male bats (n = 70) for 12 hours after sunset for 13 nights. Bats were captured in Reserva Biológica de Guaribas (Paraíba, Brazil) using mist nets. Blood glucose was analyzed with a portable glucometer. Supporting our assumptions, the number of hours after sunset and BCI presented significant positive correlations with glucose levels in A.planirostris. Reproductive phase did not present a significant correlation with any other variables. As we predicted, glucose level can be used as proxy for morphometric BCI and it can be measured with a simple portable glucometer. The increase both in glucose and BCI around the night can be explained by the efficient assimilation of nutrients present in fruits ingested by bats and the quick metabolism that increases the levels of glucose (an other nutrients) in blood, increasing the body mass.

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