Manganese Levels in Plant-based Diets May Exceed U.S. Dietary Recommendations-an Examination of the Ornish and DASH Diets (P24-011-19)
Abstract Objectives Manganese (Mn) is a dietary mineral critical for life, yet high levels of Mn can lead to symptoms of toxicity. The Mn content in food varies considerably and is most concentrated in plant-based foods, whole grains, legumes, nuts, etc. The adult adequate intake (AI) for Mn is 1.8 mg/day for women and 2.3 mg/day for men while the tolerable upper intake level (UL) is 11 mg/day for men and women. Mn absorption and bioavailability of Mn is affected by an individual's nutrition status and dietary factors. When Fe status is low Fe absorption is enhanced, subsequently increasing Mn absorption as well. Increasing evidence in support of the heart health benefits of plant-based diets has led to a rise in medically prescribed modern diets such as the Ornish diet. By design, this and other plant-based diets have a higher propensity to include Mn-rich foods. It is hypothesized that the average Mn content of the plant-based, Ornish diet will be significantly higher than that of the omnivorous Dietary Approaches to Stop Hypertension (DASH) diet. The objective of this research study is to assess the Mn levels in medically prescribed diets and compare them to current dietary standards. Methods The Mayo Clinic offers a three-day sample DASH diet menu (www.mayoclinic.org) and the Ornish diet has a three-day sample menu (www.ornish.com) complete with quantified ingredients available in the USDA National Nutrient Database. An assessment of the prescribed diets included quantifying Mn, iron (Fe), and energy (kcal). A trained researcher then manually downloaded and tabulated the nutrient profile for each ingredient. Daily values for kcal, Mn, and Fe were calculated and compared against each other and the Dietary Reference Intakes. Results The Ornish diet contained an average daily Mn content exceeding the UL, 11.5 mg/day, while the average daily Mn of the DASH diet was 7.5 mg/day. These values did not differ significantly (P = 0.125). Conclusions Both diets were significantly higher in Mn than the AI's and the Ornish diet demonstrated Mn levels higher than the UL and the DASH diet. This may indicate that people following a medically-prescribed, plant-based diet have an intake that exceeds the UL for Mn. Future research is needed to determine if the AI for Mn, which is based on typical consumption, is in need of an update, and if there are any risks or concerns for those following a plant-based diet. Funding Sources none.