scholarly journals Lifestyle Behavioral Factors and Integrative Successful Aging Among Puerto Ricans Living in the Mainland United States

2020 ◽  
Author(s):  
Michelle A Lee-Bravatti ◽  
H June O’Neill ◽  
Renee C Wurth ◽  
Mercedes Sotos-Prieto ◽  
Xiang Gao ◽  
...  
Keyword(s):  
Puerto Rican ◽  
Successful Aging ◽  
Puerto Ricans ◽  
Health Study ◽  
Physical Domain ◽  
Lifestyle Behaviors ◽  
Behavioral Factors ◽  
Definition Of ◽  
Psychosocial Domain

Abstract Background Few studies have assessed multidimensional models for predicting successful aging that incorporate both physical and cognitive-psychosocial elements among minority populations. This study aimed to establish a comprehensive lifestyle behavioral factors (cLBF) score and an integrative successful aging (ISA) score and explore their associations among older Puerto Rican adults. Methods Data were assessed from 889 adults (45–75 years) participating in the longitudinal (baseline and 2-year follow-up) Boston Puerto Rican Health Study. Higher cLBF score (range 0–10) indicates healthier behaviors (nonsmoking, lack of sedentarism, physical activity, high diet quality, and adequate sleep). The physical domain score of ISA included 8 components (functional impairment, hypertension, diabetes, cancer, cardiovascular disease, respiratory disease, arthritis, osteoporosis) and ranged 0–11. The cognitive-psychosocial domain of ISA included 5 components (cognitive impairment, depressive symptoms, social support, perceived stress, and self-rated health) and ranged 0–10. The sum of both domains comprised the ISA score, ranging 0–21. Higher scores of ISA and its domains indicate more successful aging. Results At 2 years, the mean ± SD of cLBF score was 4.9 ± 1.8, and ISA was 10.1 ± 3.3. In multivariable-adjusted models, cLBF score was significantly and positively associated with 2-year change in overall ISA (β [95% CI]: 0.15 [0.07, 0.24] points), in physical domain (0.09 [0.04, 0.13] points), and in cognitive-psychosocial domain (0.08 [0.02, 0.14] points). Conclusions Maintaining healthier lifestyle behaviors may contribute to successful aging through both physical and cognitive-psychosocial domains. The results support using a multidimensional definition of successful aging in Puerto Ricans and evaluating it in other populations.

scholarly journals Neighborhood socioeconomic context and change in allostatic load among older Puerto Ricans: The Boston Puerto Rican health study

2015 ◽  
Vol 33 ◽  
pp. 1-8 ◽  
Author(s):  
Marcia P. Jiménez ◽  
Theresa L. Osypuk ◽  
Sandra Arevalo ◽  
Katherine L. Tucker ◽  
Luis M. Falcon
Keyword(s):  
Puerto Rican ◽  
Allostatic Load ◽  
Puerto Ricans ◽  
Health Study ◽  
Socioeconomic Context

scholarly journals Influence of Type II Diabetes and High Depressive Symptoms on the Likelihood for Developing Activities of Daily Living (ADL) Disability and Mortality in Older Puerto Ricans

2017 ◽  
Vol 29 (6) ◽  
pp. 1079-1095 ◽  
Author(s):  
Brian Downer ◽  
Michael Crowe ◽  
Kyriakos S. Markides
Keyword(s):  
Depressive Symptoms ◽  
Activities Of Daily Living ◽  
Puerto Rican ◽  
Type Ii Diabetes ◽  
Daily Living ◽  
Psychiatric Treatment ◽  
Puerto Ricans ◽  
Elderly Health ◽  
Adl Disability

Objective: To examine the development of activities of daily living (ADL) disability and mortality according to diabetes and high depressive symptoms among Puerto Rican adults aged 60 and older. Method: Data came from Wave I and Wave II of the Puerto Rican Elderly: Health Conditions Study ( n = 3,419). Logistic regression was used. Using insulin and receiving psychiatric treatment were proxy measures of disease severity for diabetes and depressive symptoms, respectively. Results: High depressive symptoms at baseline were associated with developing ADL disability (OR = 2.21; 95% CI = [1.68, 2.91]). Diabetes at baseline was associated with mortality at follow-up (OR = 1.72; 95% CI = [1.34, 2.19]). Baseline diabetes was associated with developing ADL disability but only for those who reported using insulin (OR = 1.69; 95% CI = [1.08, 2.61]). Participants with comorbid diabetes and high depressive symptoms had the highest odds for developing ADL disability and mortality. Discussion: Diabetes and high depressive symptoms are risk factors of developing ADL disability and mortality for older Puerto Ricans.

Prospective Study of Plant-Based Dietary Patterns and Diabetes in Puerto Rican Adults

2021 ◽  
Author(s):  
Ashley C Flores ◽  
Christopher Heron ◽  
Jung In Kim ◽  
Bryan Martin ◽  
Laila Al-Shaar ◽  
...  
Keyword(s):  
Puerto Rican ◽  
Dietary Patterns ◽  
Diabetes Management ◽  
Depressive Symptomatology ◽  
Plasma Concentrations ◽  
Cox Proportional Hazards ◽  
Hypoglycemic Agents ◽  
Health Study ◽  
Dietary Index

ABSTRACT Background Vegetarian-type dietary patterns have been associated with reducing the risk of developing diabetes and may function as an effective strategy for diabetes management. Objectives We aimed to examine the associations between adherence to plant-based diet indices and the risk of developing diabetes in the Boston Puerto Rican Health Study. Methods Puerto Rican adults (n = 646), aged 45–75 y and free of diabetes at baseline, were included. Dietary intake was assessed via a validated FFQ. Three plant-based dietary indices were calculated: an overall plant-based diet index (PDI), a healthful plant-based diet index (hPDI), and an unhealthful plant-based diet index (uPDI). Incident diabetes was defined as fasting plasma glucose ≥ 126 mg/dL (7.0 mmol/L), glycated hemoglobin ≥ 6.5% (48 mmol/mol), or use of hypoglycemic agents during follow-up. Cox proportional hazards were used to evaluate associations between the dietary patterns and incidence of diabetes, adjusting for potential confounders, such as age, sex, socioeconomic status, lifestyle factors, obesity, total energy intake, depressive symptomatology, and plasma concentrations of lipids. Results During a mean of 4.2 y of follow-up, we identified 134 diabetes cases. After adjustment for covariates, higher hPDI was associated with lower risk of developing diabetes (adjusted HR for the highest compared with the lowest tertile: 0.54; 95% CI: 0.31, 0.94; P-trend = 0.03). In contrast, the PDI and uPDI were not significantly associated with the risk of diabetes (P-trend > 0.3 for both). Conclusions The healthful plant-based dietary index, but not the total plant-based dietary index, was inversely associated with diabetes risk. These findings suggest that the quality of plant-based diets must be considered when recommending plant-based diets for the prevention of diabetes. This trial was registered at clinicaltrials.gov as NCT01231958.

Abstract P014: Life’S Simple 7 And Fibroblast Growth Factor 23: The Boston Puerto Rican Health Study.

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Chinedu C Ochin ◽  
Sherman Bigornia ◽  
Mahdi O Garelnabi ◽  
Katherine L Tucker
Keyword(s):  
Puerto Rican ◽  
Fasting Glucose ◽  
Fibroblast Growth Factor 23 ◽  
Left Ventricular ◽  
Health Study ◽  
Life’S Simple 7 ◽  
Life's Simple 7 ◽  
Fgf 23 ◽  
Group 1

Introduction: FGF-23 is a phosphatouric hormone which also serves as a plasma biomarker that mediates pathologic cardiac remodeling, such as left ventricular hypertrophy or myocardial fibrosis, and is associated with increased cardiovascular mortality. However, limited evidence is available on lifestyle-related factors associated with circulating concentration of this emerging cardiovascular risk factor. Objective: Our aim was to measure the association between the American Heart Association’s Life’s Simple 7 (LS7) and circulating FGF-23 concentration among Puerto Rican adults. Methods: Data are from Boston Puerto Rican Health Study (BPRHS) participants (mean age 56.2 years, 77% female) at baseline and at approximately 8-y follow-up (n=410). LS7 was calculated at baseline and includes 4 physiological (BMI, total cholesterol, blood pressure, and fasting glucose) and 3 behavioral factors (smoking, physical activity, and diet). Each component was categorized using a constituent scoring system (ideal=2; intermediate=1; Poor=0) and these were summed to calculate the total LS7 score. Participants were categorized into 5 LS7 groups as follows: 1) score 1-4 (n=105), 2) 5 (n=76), 3) 6 (n=89), 4) 7 (n=69), and 5) 8-12 (n=71). Fasting plasma FGF-23 concentration at 8-y follow-up was measured by ELISA. Associations between baseline LS7 score and 8-y FGF-23 were assessed using ANCOVA, adjusted for age and sex (model 1), and additionally for history of cardiovascular disease and poverty-income-ratio (model 2). Results: Relative to participants in LS7 group 1 (2.98 ± 1.09 mg/dL), those in groups 5 (1.63 ± 1.12 mg/dL, p=0.0001) had significantly lower FGF-23 concentration (model 1, P-trend=0.0001). After considering additional confounders, FGF-23 concentration among LS7 group 5 (1.69 ± 1.12 mg/dL, p=0.0007) remained significantly lower than in group 1 (2.95 ± 1.09 mg/dL). The p-trend across categories was also significant at p=0.0007. In additional analyses, LS7 components for smoking (ideal vs. poor, 2.07 ± 1.10 mg/dL vs. 2.87 ± 1.10 mg/dL, p=0.01) and fasting glucose (ideal vs. poor, 2.03 ± 1.07 mg/dL vs. 2.90 ± 1.09 mg/dL, p=0.004), but no other components, were associated with FGF-23 concentration. Conclusions: Optimal LS7 status was associated with lower 8-y mean plasma FGF-23 concentration. Efforts to target LS7 components, particularly smoking and glucose control, may improve FGF-23 concentration among Puerto Rican adults.

Flowing through My Veins

2017 ◽  
Author(s):  
Isar P. Godreau
Keyword(s):  
Nineteenth Century ◽  
Puerto Rico ◽  
Puerto Rican ◽  
Puerto Ricans ◽  
National Pride ◽  
Cultural Policies ◽  
Puerto Rican Culture ◽  
The 1950S ◽  
Definition Of

This chapter discusses how the scripts of blackness developed in tandem with discourses of race mixture that supported populist forms of governance and cultural policies in the 1940s and 1950s. The biological definition of Puerto Ricans as a mixture of three races—the Taíno, the Spanish, and the African—had been circulating since the nineteenth century in both criollo and U.S. writings about Puerto Rico, but before the 1950s, this was not institutionally constructed as an object of national pride. It was after the 1950s that the ideology of race mixture was taken up as a populist State discourse and implemented through the Institute of Puerto Rican Culture. Indeed, race mixture became a central part of the state's cultural program of development and modernization for Puerto Rico.

scholarly journals Serum Vitamin D and Depressive Symptomatology among Boston-Area Puerto Ricans

2020 ◽  
Vol 150 (12) ◽  
pp. 3231-3240 ◽  
Author(s):  
Neha Sahasrabudhe ◽  
Jong Soo Lee ◽  
Tammy M Scott ◽  
Laura Punnett ◽  
Katherine L Tucker ◽  
...  
Keyword(s):  
Vitamin D ◽  
Puerto Rican ◽  
Depressive Symptomatology ◽  
Puerto Ricans ◽  
Sensitivity Analyses ◽  
Longitudinal Analyses ◽  
Cross Sectional ◽  
Baseline Serum ◽  
Vitamin D Supplement

ABSTRACT Background Low vitamin D status, assessed using serum 25-hydroxyvitamin D [25(OH)D] concentration, has been associated with depression, but research among minority populations, such as Puerto Ricans is limited. We examined the association between serum 25(OH)D and self-reported depressive symptomatology across 3 waves of follow-up in a cohort of Puerto Rican adults residing in Massachusetts. Objectives We evaluated the cross-sectional and longitudinal associations between serum 25(OH)D and self-reported depressive symptoms in the Boston Puerto Rican Health Study (BPRHS) cohort. Methods Participants of the BPRHS were evaluated for depressive symptoms using the Center for Epidemiologic Studies Depression Scale (CES-D). Serum 25(OH)D was measured at baseline (n = 1434), year 2 (n = 1218), and year 5 (n = 914). We categorized serum 25(OH)D concentration as sufficient (≥20 ng/mL), insufficient (12 to <20 ng/mL), and deficient (<12 ng/mL). Multivariable linear regression was used for cross-sectional analyses at baseline, and repeated measures mixed effects modeling was used over 3 waves of follow-up for longitudinal analyses. We conducted sensitivity analyses in vitamin D supplement nonusers and participants with complete data on baseline serum 25(OH)D and CES-D at all 3 visits. Results Serum 25(OH)D concentration was not associated with CES-D score in cross-sectional analysis [β = −0.85; 95% CI: −2.80, 1.10 for deficient compared with sufficient 25(OH)D; P-trend = 0.59] or in longitudinal analyses over 5 y [β = −0.41; 95% CI: −1.95, 1.13 for deficient compared with sufficient 25(OH)D; P-trend = 0.93]. Results were similar in sensitivity analyses restricted to vitamin D supplement nonusers (n = 1371) and in analyses conducted in participants with complete measures of baseline serum 25(OH)D and CES-D score at all 3 visits (n = 887) [β = −0.12; 95% CI: −1.98, 1.74 for deficient compared with sufficient 25(OH)D; P-trend = 0.93]. Conclusions We did not observe a significant association between serum 25(OH)D and depressive symptomatology in the BPRHS cohort.

scholarly journals Gut Microbiota Metabolites and Cardiometabolic Risk Among Older Puerto Ricans: Findings from the Boston Puerto Rican Health Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1378-1378
Author(s):  
Shilpa Bhupathiraju ◽  
Megu Baden ◽  
Danielle Haslam ◽  
Liming Liang ◽  
Clary Clish ◽  
...  
Keyword(s):  
High Risk ◽  
Gut Microbiota ◽  
Puerto Rican ◽  
Cardiometabolic Risk ◽  
Puerto Ricans ◽  
Conditional Logistic Regression ◽  
Health Study ◽  
Future Research ◽  
High Risk Population ◽  
Cross Sectional

Abstract Objectives Puerto Ricans are the second-largest Hispanic sub-group and have high rates of type 2 diabetes (T2D). Yet, there is limited understanding of the molecular pathways that contribute to cardiometabolic risk in this high-risk group. We hypothesized that circulating gut microbiota metabolites, which have been linked to T2D risk in non-Hispanic whites, are associated with a higher T2D likelihood and cardiometabolic risk markers among older Puerto Ricans. Methods We developed a case-control study within the Boston Puerto Rican Health Study (BPRHS) with 275 prevalent T2D cases and 275 age and sex matched controls (mean age = 58.1 y, 71% female). We used LC/MS to measure baseline plasma gut microbiota metabolites (L-carnitine, betaine, choline, trimethylamine oxide [TMAO], and betaine: choline). We used conditional logistic regression to model the likelihood of prevalent T2D for each standard deviation (SD) increase in metabolites. Among controls free of T2D, we examined cross-sectional and prospective (2-year) linear associations (β [SD]) between metabolites and glycemia and dyslipidemia measures. Results After multivariable adjustment, significant differences in T2D likelihood [OR (95% CI)] were observed for each SD increase in L-carnitine [0.78 (0.62–0.99)], choline [1.33 (1.05–1.68)], betaine: choline [0.69 (0.54–0.88)], and TMAO [1.32 (1.04–1.67)]. We replicated findings for L-carnitine and betaine: choline in the WHI metabolomics study. Among BPRHS controls, cross-sectionally, higher betaine was associated with lower HOMA-IR (−9.97 [3.02]), insulin (−9.78 [2.83]), triglycerides (−11.4 [2.54]), and higher HDL-C (2.05 [0.65]). Prospectively, higher betaine and betaine: choline were associated with lower HOMA-IR (betaine −11.5 [3.63], betaine: choline −9.57 [3.68]), insulin (betaine −9.21 [3.27], betaine: choline −8.01 [3.31]), and glucose (betaine −2.17 [0.74], betaine: choline −1.58 [0.76]) concentrations, while higher choline was prospectively associated with higher triglycerides (5.17 [2.09]). No associations were seen between L-carnitine, TMAO, and cardiometabolic markers among controls. Conclusions Plasma betaine, choline, and betaine: choline may be markers of cardiometabolic risk in this high-risk population. Future research should examine dietary and lifestyle correlates of betaine and choline. Funding Sources NIH.

scholarly journals Untargeted Metabolomics and Cognitive Function in the Boston Puerto Rican Health Study (OR32-03-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Natalia Palacios ◽  
Jong Soo Lee ◽  
Tammy Scott ◽  
Katherine Tucker
Keyword(s):  
Amino Acid ◽  
Cognitive Function ◽  
Puerto Rican ◽  
Puerto Ricans ◽  
Separation Distance ◽  
Partial Least Square ◽  
Least Square ◽  
Health Study ◽  
Food Component ◽  
The Mean

Abstract Objectives We sought to determine the metabolic signature associated with poor vs good cognition in a cohort of Boston-area Puerto Ricans. Methods We studied 638 participants the Boston Puerto Rican Health Study (BRPHS), a prospective Boston-area cohort study of Puerto Ricans, with comprehensive metabolite profiling (>700 metabolites) at baseline and a concurrent assessment of global cognitive function. Cognition was assessed at baseline using a comprehensive cognitive battery from which a global cognitive score was derived. Our analysis focused on 638 annotated metabolites that had reported values in ≥80% of the participants. We performed univariate linear regression analyses to identify metabolites significantly associated with global cognitive score.To examine whether these metabolites could then discriminate between the low from (<=1SD below the mean, N = 85) the high (>=1SD above the mean, N = 99) cognition groups, and to identify metabolites that could best discriminate between low and high cognition groups, we conducted partial least square discrimination analysis (PLS-DA). We used separation distance as the test statistic and plotted the scores of the first two partial least square components to inspect the separation of cases from controls. We also identified metabolites contributing most strongly to the separation (VIP > 1). Results 113 metabolites were significantly associated with cognitive function in univariate analyses. In PLS-DA analyses using these 113 metabolites. when plotting the first two PLS components, there was a clear separation between the low and high cognition groups and controls (Figure 1) (permutation test based on separation distance p-value 0.012) (Figure 1). 23 metabolites had a Variable Importance in Projection (VIP) scores > 1. The metabolites with the highest VIP scores and elevated in the low relative to the high cognition group included cystathionine (amino acid and downstream metabolite of homocysteine), quinate (xenobiotic/food component, component medication used to treat malaria) and p-cresol-glucuronide (amino acid). (Table 1). Conclusions In this cross sectional study of Boston Area Puerto Ricans, we observed a separation between high and low cognitive function groups in the Boston Puerto Rican study based on metabolomic profiles. Funding Sources This work was supported by the National Institutes of Health. Supporting Tables, Images and/or Graphs

scholarly journals Prospective Relations Between the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean Diet (MeDS) Scores and Self-Report Arthritis Among Puerto Rican Adults

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 49-49
Author(s):  
Kelsey Mangano ◽  
Sabrina Noel ◽  
Xiyuan Zhang ◽  
Katherine Tucker
Keyword(s):  
Puerto Rican ◽  
Fixed Effects ◽  
Self Report ◽  
Dietary Quality ◽  
Health Study ◽  
Multiple Time ◽  
Dash Score ◽  
Logistic Regression Models ◽  
Time Points

Abstract Objectives To investigate the prospective associations of DASH and MeDS with self-reported arthritis across three time points [baseline, 2y and 6y follow-up] among Puerto Rican older adults. Methods Data are from the Boston Puerto Rican Health Study, a prospective cohort of Puerto Rican adults aged 45 to 75 y. Individuals were included if they presented with diet and arthritis data at minimum 2/3 visits (n = 1210). Dietary quality indices (DASH and MeDS) were derived from dietary data assessed by FFQ. Participants self-reported arthritis. Generalized linear mixed modeling was used to estimate multivariable hierarchical logistic regression models, accounting for multiple time points (baseline, 2y and 6y). Models were adjusted for smoking, alcohol, physical activity, sex, estrogen, education, diabetes (y/n), BMI, and age. Results Among participants with data at all timepoints (n = 958), the mean time from baseline to last follow-up was 6.2 ± 0.97y. Mean age was 63 ± 7y (range 49–81y at follow-up), 72% were women, mean BMI was 31 ± 6 kg/m2, DASH score 24.0 ± 4.3 (10–37), and MeDS 5.0 ± 1.2 (0–9). MeDS was not predictive of arthritis at follow-up in crude (fixed effects estimate: −0.016, P = 0.70) nor adjusted (−0.016, P = 0.73) models. DASH score was inversely associated with arthritis in crude models (0.032, P = 0.01); but was no longer significantly associated after controlling for confounders, including age (0.013, P = 0.39). Age was significantly associated with DASH score in final models (fixed effects estimate: 0.08, P &lt; 0.001). However, no significant interaction of DASH score with age was observed (P = 0.31). Conclusions The current results do not support a prospective association between MeDS or DASH score with self-reported arthritis among Puerto Rican adults. Previous studies suggest higher dietary quality is protective of arthritis, particularly in younger cohorts (&lt;55y). Future studies are needed to determine if early intervention with DASH is more predictive of arthritis onset. Funding Sources P01 AG023394, P50 HL105185, R01 AG027087. SEN is supported by K01 AR067894.

scholarly journals The association between metabolic syndrome and successful aging- using an extended definition of successful aging

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0260550
Author(s):  
Yi-Hsuan Lin ◽  
Jeng-Min Chiou ◽  
Ta-Fu Chen ◽  
Liang-Chuan Lai ◽  
Jen-Hau Chen ◽  
...  
Keyword(s):  
Older Adults ◽  
Metabolic Syndrome ◽  
Successful Aging ◽  
Density Lipoprotein ◽  
Community Dwelling ◽  
University Hospital ◽  
Time Interaction ◽  
Definition Of ◽  
Community Dwelling Older Adults

Objectives To examine the association between metabolic syndrome (MetS) and successful aging among community-dwelling older adults. Methods Adults aged ≥ 65 years who participated in the senior health checkup program at National Taiwan University Hospital during 2011–2013 were recruited (N = 467 at baseline). The participants were followed after 4 years and 6 years. MetS was assessed at baseline. Successful aging was evaluated at baseline, 4-year follow-up, and 6-year follow-up. We adopted an extended definition of successful aging, which was defined as three major domains: physiological, psychological, and sociological and economic domains. Generalized linear mixed models were used to assess the association between MetS and successful aging adjusting for time (follow-up years), age, sex, years of education, alcohol consumption and MetS×time interaction term. Results The mean age of the study population was 72.9 (SD 5.5) years. The absence of baseline MetS had a positive effect on the probability of successful aging over six years. The absences of abdominal obesity, hyperglycemia, reduced high-density lipoprotein cholesterol, and hypertension were associated with the physiological successful aging. The absence of hypertension was the most significant predictor of physiological successful aging [aOR (95% CI) = 2.76 (1.67–4.58), p<0.001]. Significant increased trend was found in the overall and physiological successful aging across MetS status (No MetS, pre MetS, MetS; Ptrend <0.001). Conclusions We found that MetS is a risk factor of successful aging among community-dwelling older adults. Public health policy should aim at avoidance of MetS in order to facilitate successful aging in older population.

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