scholarly journals Relationships Between Salivary Cortisol Slope and Neuropsychiatric Symptoms in Persons Living With Dementia

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 437-437
Author(s):  
Fanghong Dong ◽  
G Adriana Perez ◽  
Nancy Hodgson ◽  
Yeji Hwang

Abstract While a flatter diurnal cortisol slope has been related to poor health outcomes in healthy populations, little is known about this relationship in persons living with dementia (PLWD). The purpose of this study was to examine the association between diurnalcortisol slope and neuropsychiatric symptoms in PLWD. Secondary data analysis was conducted using baseline data from the Healthy Patterns Study (N=168). Diurnal cortisol slope was calculated using the difference between changes in salivary cortisol from 30 minutes after awakening to bedtime. Spearman rho coefficients were used. Flatter cortisol slope was associated with the presence of symptoms of agitation (r=-0.191, p=0.013) and disinhibition (r=-0.168, p=0.03). Steeper cortisol slope was related to a more severe level of anxiety symptoms (r=0.36, p=0.009) and higher frequency of insomnia (r=0.292, p=0.011). We found that cortisol slope was associated with neuropsychiatric symptoms in PLWD. Future research is needed to examine the mechanisms underlying the relationships.

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 436-437
Author(s):  
Nancy Hodgson ◽  
Fanghong Dong

Abstract Circadian rhythm disturbances (CRD) are commonly seen in people living with dementia. A clear understanding of the role of CRD in dementia etiology will be beneficial by exploring the exogenous factors (externally influence the duration of sleep hours, such as light/dark cycles) and endogenous factors (internal biological rhythm, such as diurnal cortisol pattern). This symposium will apply a chronobiological approach to study exogenous and endogenous factors that influence circadian rhythm and their effects on sleep and neuropsychiatric symptoms in persons living with dementia (PLWD). Four paper presentations will use secondary data analysis of data from the Healthy Patterns Clinical Trial (NCT03682185), a randomized controlled trial of a home-based activity intervention designed to improve circadian rhythm disorders in PLWD. We will first describe the circadian rhythm pattern reflected by endogenous factors (salivary cortisol), then examine salivary cortisol (endogenous) and white light intensity (exogenous) and on subjective sleep and neuropsychiatric symptoms (including depression) in PLWD, respectively. In session 1, we will present cortisol diurnal rhythm pattern in PLWD using a cross-sectional design. In session 2, we will discuss the relationship between salivary cortisol indicators and depressive symptoms. In session 3, we focus on the association between diurnal cortisol slope and neuropsychiatric symptoms using the baseline data. In session 4, we describe the association between evening white light exposure and subjective sleep. The discussant will describe how these findings build on our understanding the nature of circadian rhythm disturbance in dementia and inform future research and treatment approaches.


2020 ◽  
Vol 8 (T1) ◽  
pp. 570-573
Author(s):  
Meita Veruswati ◽  
Al Asyary ◽  
Rony Darmawansyah Alnur ◽  
Guspianto Guspianto

BACKGROUND: In anticipation of coronavirus disease (COVID)-19’s transmission peak, Eid-al-Fitr homecoming (mudik) has officially been banned by the Indonesian government interlocal but not local in welcoming this religious Muslim celebration. This local Mudik is held by traveling among regional provinces and is still allowed by each local government, including Java, which has the highest transmission of COVID-19 in Indonesia. AIM: This study aims to present the difference between COVID-19 status before and during local Mudik on Java during Ramadhan with the implementation of large-sale social distancing applied in Jakarta, Indonesia. METHODS: This research was employed by secondary data analysis that was obtained from surveillance data from related authorities, including the Ministry of Health and all local governments of Java, which consisted of four provinces and Jakarta. Incidence and suspect statuses of COVID-19, which were examined in the study, were presented in daily rates with before and during local Mudik in four provinces: Jawa Barat, Yogyakarta, Banten, and Jawa Tengah. RESULTS: The number of positive confirmed patients differed significantly with before and during local Mudik (p < 0.05; mean difference = −/negative values). CONCLUSION: This study’s findings showed that the local Mudik increased the number of COVID-19 cases in four provinces in Java, which these provinces were designated as Mudik destinations by travelers coming from Jakarta during the end of Ramadhan season.


2019 ◽  
Vol 4 (1) ◽  
pp. 127-136
Author(s):  
Pandoyo Pandoyo

This study aims to estimate the effect of CAR, LDR, BOPO, and NPL on profitability (ROA) in rural banks in West Java Province for the period of 2012-2016. Data was collected from secondary data and data analysis using multiple linear regression. The results showed that: only BOPO proved to have a negative and significant effect on ROA. While other variables, namely CAR and NPL have a positive but not significant effect, and NPL has a negative effect but not significant to ROA. The results of the study provide practical implications for management to pay attention to BOPO as the main predictor of ROA. Suggestions for future research are explained in the article. Keywords: CAR, LDR, BOPO, NPL, ROA


2019 ◽  
Vol 27 (2) ◽  
pp. 207-225
Author(s):  
Suhartono Suhartono ◽  
Achmad Tjahjono

The purpose of this study is: to test whether there are differences in financial performance between Savings and Loans Cooperatives and Sharia Financing (KSPPS) and Conventional Savings and Loans Cooperatives (KSP) by comparing 5 (five) variables, namely: Liquidity, Solvency, Economic Rentability, Asset Growth , and Member Growth. This study uses secondary data with a total of 10 (ten) Cooperatives with details of 5 (five) Savings and Loan Cooperatives and Shari’ah Financing (KSPPS) and Conventional Savings and Loans Cooperatives (KSP) of 5 (five) with observation periods between 2013 - 2017. The statistical analysis method used is the two average differences used to test the difference in performance of the two data groups with 5 (variables) measured. The results showed that the variable Liquidity, Solvabolity, Asset Growth, and Member Growth there was no difference in performance between Savings and Loans Cooperatives and Sharia Financing (KSPPS) with Conventional Savings and Loans Cooperatives (KSP). While the Economic Rentability variable shows a difference, namely KSPSS has better performance than KSP. The limitations of this study are the shorter observation time and the small number of samples. While suggestions can be given for future research is that more research samples can be added, research variables can also be added and the research area can be expanded.


2017 ◽  
Vol 5 (2) ◽  
pp. 34
Author(s):  
Sarah Meilita Indrani ◽  
Hernawan Hadi

<p>Abstract<br />This  article  aims  to  determine  online  arbitration  conformity  with  the  legal  system  in  Indonesia  and to determine about the application of online arbitration in Indonesia as one of the alternative dispute resolution business. In this article also contains the online arbitration procedure and also contains about weaknesses and advantages online arbitration as a means of dispute resolution business.This article is an empiric legal research. The location of the research at the BANI Arbitration Center, Jakarta. The specification of this article is the descriptive reserach, which is a research meant to give descriptions concerning research results accompanied by the analysis of the prevailing law. The article approach in this study is the approach of legislation and qualitative approach. This type of article data used include primary and  secondary data.  Source of  research  data collection  techniques  used  is  field  study  and literature study. Data analysis technique used in this research is qualitative data analysis technique.The result showed that online arbitration does not conflct with the Act No. 30 of 1999 about Arbitration and Alternative Dispute Resolution. While about the application of online arbitration actually have not been applied in Indonesia, it’s just that the online arbitration procedure is the same thing with the conventional arbitration procedure, the difference in online arbitration conduct online using internet network.</p><p>Keywords:  Online  Arbitration,  Act  No.  30  of  1999 about Arbitration and Alternative Dispute Resolution, BANI Arbitration Center</p><p>Abstrak<br />Artikel ini bertujuan untuk mengetahui kesesuaian arbitrase online dengan sistem hukum di Indonesia dan untuk mengetahui penerapan arbitrase online di Indonesia sebagai salah satu cara penyelesaian sengketa bisnis. Dalam artikel ini juga berisikan mengenai prosedur daripada arbitrase online serta kelebihan dan kelemahan arbitrase online sebagai cara penyelesaian sengketa bisnis. Artikel ini merupakan penelitian hukum empiris. Lokasi penelitian yaitu di Badan Arbitrase Nasional Indonesia, Jakarta. Spesifikasi artikel ini adalah penelitian deskriptif, yaitu penelitian yang dimaksudkan untuk memberikan gambaran tentang hasil penelitian disertai analisa mengenai peraturan perundang-undangan yang berlaku. Pendekatan artikel dalam penelitian ini adalah pendekatan perundang-undangan dan pendekatan kualitatif. Jenis data  artikel  yang  digunakan  meliputi  data  primer  dan  data  sekunder.  Teknik  pengumpulan  sumber data penelitian yang digunakan yaitu studi lapangan dan studi kepustakaan. Teknik analisis data yang digunakan dalam penelitian ini adalah teknik analisis data kualitatif. Hasil penelitian menunjukkan bahwa arbitrase online tidak bertentangan dengan Undang-Undang Nomor 30 Tahun 1999 tentang Arbitrase dan Alternatif  Penyelesaian  Sengketa. Sedangkan untuk penerapan dari arbitrase online itu sendiri <br />sebenarnya belum diterapkan di Indonesia, hanya saja prosedur untuk melakukan arbitrase online sama hal nya dengan prosedur arbitrase konvensional, perbedaannya pada arbitrase online dilakukan secara online dengan menggunakan jaringan internet.</p><p>Kata kunci: Arbitrase Online, Undang-Undang Nomor 30 Tahun 1999 tentang Arbitrase dan Alternatif Penyelesaian Sengketa, Badan Arbitrase Nasional Indonesia</p>


2019 ◽  
Vol 58 (5) ◽  
pp. 564-570
Author(s):  
Zachary Willis ◽  
Delesha Miller Carpenter ◽  
Robyn Sayner ◽  
Betsy L. Sleath

Children with asthma are exposed to antibiotics more frequently than their peers. The quality of provider-patient discussion about antibiotics is unknown. In this secondary data analysis, we reviewed existing transcripts of audiotaped adolescent asthma visits using a standardized coding sheet to analyze the quality of communication about antibiotics. Of 539 transcripts, we identified 12 discussions about antibiotics. No patient or parent requested antibiotics. In most cases, discussion was limited to assessment of drug allergies and preferred formulation. In 5 cases (42%), the prescribed antibiotic was not named. We propose a set of communication elements that should be included whenever antibiotics are prescribed, classified into ( a) Essential, such as the drug name and dosing schedule; ( b) Encouraged, such as expected response to therapy; or ( c) Situational, such as discussion of alternatives to antibiotics. Future research should further explore the quality of antibiotic-related conversations among different groups of providers and patients.


Author(s):  
Julia Söhnholz

Abstract: This article explores West-African modes of mobilisations confronting the externalisation of European borders. At the hands of a secondary data analysis, this article critically examined the most recent publications in relation to this topic, guided by the following research question: How do West-African modes of mobilisations challenge EU mobility regimes? This research identified governments, local organisations, (potential) migrants, expelled migrants, media, academia and writers and transnational social movements as relevant actors with different modes of action. This research suggests that there are multiple West-African modes of mobilisations that challenge EU mobility regimes, confront the problematisation of non-sedentary lifestyles and see mobility as a strategy and a solution for a bottom-up process of globalisation and as an inherent part of West-African mobile societies; existing next to African modes of mobilisations that have become part of EU mobility regimes. The objective of this research is to promote future research by increasing the visibility and political agency of the transformative possibilities of African modes of mobilisations.


2021 ◽  
Vol 10 (3) ◽  
pp. 119-146
Author(s):  
Dora M. Y. Tam ◽  
Tracy Smith-Carrier ◽  
Siu Ming Kwok ◽  
Don Kerr ◽  
Juyan Wang

Through a secondary data analysis of administrative data of the Ontario Disability Support Program (ODSP) between 2003 and 2013, we aim to understand the interlocking challenges encountered by newcomers with disabilities in Canada that contribute to this population’s financial hardship. Our findings show that newcomers with disabilities on ODSP were more likely to have post-secondary education, to be older adults, to be married, common-law, and to be female who were divorced, separated, or widowed as compared to Canadian-born recipients, who were more likely to be less educated, younger, single and male. The ratio of Canadian-born to newcomer recipients on the ODSP was high between 2003 and 2013, indicating that the latter were under-represented on the program. Implications for this under-representation support future research to examine the full integration and participation of newcomers with disabilities in Canada.


2021 ◽  
Vol 3 (2) ◽  
pp. 206-212
Author(s):  
Andyanita Hanif Hermawati ◽  
Eka Puspitasari ◽  
Deny Yusnia Milasari

Hemoglobin is the main component of red blood cells, a conjugated protein that functions to transport oxygen and carbon dioxide. Hemoglobin examination can be done using a hematology analyzer and spectrophotometry. This study aims to determine the data analysis whether there is a difference in hemoglobin levels using a hematology analyzer and spectrophotometry in pregnant women. The method used is Literature Review; the nature of this research is descriptive. The population of this research is health journals that have been through screening, namely journals of differences in hemoglobin levels using a hematology analyzer and spectrophotometry in pregnant women. In this study, the data used are secondary data and data analysis using qualitative data. The results of the evaluation of the study by the Literature Review with hemoglobin levels in pregnant women at Hermina Hospital, Surakarta, showed that the average hemoglobin level of 30 samples of pregnant women using a hematology analyzer was below normal, namely 10.3 gr/dL and normal hemoglobin level is 12.80 gr/dL. The hemoglobin level using spectrophotometry and hematology analyzer on the sample was immediately checked, the results of the hemoglobin levels were 12.98 gr/dL and 11.70 g/dL, respectively. The hemoglobin level showed that the average hemoglobin before being given Fe-Folate with orange water was 11.71 g/dL. The conclusion of this study is the difference in hemoglobin levels is not much different, so there is no difference between the spectrophotometry and the hematology analyzer


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