scholarly journals 270 Efficacy of Bacillus subtilis and Bacillus licheniformis (BioPlus2B®) on sow lactation performance, litter growth, nursery performance and health of pigs challenged with PRRS virus post-wean

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 94-95
Author(s):  
Steve P Lerner ◽  
Sage R Becker ◽  
Scott A Dee ◽  
Steve J Kitt ◽  
Mark J Bertram ◽  
...  

Abstract Probiotics have been shown to support normal growth and immune function in pigs in challenging environments. A commercial probiotic (BioPlus2B®) containing two microbial species (Bacillus subtilis and Bacillus licheniformis) was tested to determine its effect on lactation of sows, pre-weaning performance of litters, and post-weaning performance of pigs challenged with PRRS virus. Sows (n = 120) were fed to meet or exceed NRC 2018 requirements and divided into two treatment groups: control and BioPlus2B®. BioPlus2B® was fed daily at an equivalent of 1.6 x 109CFU/kg and daily feed intake was recorded. Production practices were closely monitored in order to reduce the risk of bacteria cross-contamination between treatment groups and to maintain responsible animal welfare practices. By 24 hours post-farrow, piglets were cross-fostered within treatment group and subsequently weighed. They were weighed again on day 17. Upon weaning at approximately 21 days, piglets from each treatment group were separated into one of three BSL2 rooms and allocated to one of 36 pens per treatment for a 28-day growth study. The treatment group was fed BioPlus2B® daily at 1.1 x 109CFU/kg. At seven days post-wean, pigs were infected IM with 2 x 103.5 TCID 50 of the PRRS virus. Sow, litter, or pen was considered the experimental unit except for birth and wean weights. Sows that consumed BioPlus2B® daily birthed heavier piglets, consumed more feed throughout lactation, and tended to wean heavier pigs than Control sows. Pigs that consumed BioPlus2B® post-wean resulted in greater ADG, ADG:ADFI, and reduced mortality after PRRS infection. Data is expressed as least square means ±SEM. Values at P< 0.05 are considered significantly different while values between 0.05< P≤0.10 are considered a trend. In summary, feeding a defined probiotic supports optimal performance of sows and litters and effective immune responses of pigs challenged with respiratory disease.

Author(s):  
Adam Redhead ◽  
Fur Fatin Inazlina Noor Azman ◽  
Anis Izzaty Nasaruddin ◽  
Thien Vu ◽  
Fernanda Santos ◽  
...  

Salmonella is the leading cause of bacterial foodborne zoonoses in humans. Thus, the development of strategies to control bacterial pathogens in poultry is essential. Peanut skins, a considerable waste by-product of the peanut industry is discarded and of little economic value. However, peanut skins contain polyphenolic compounds identified that have antimicrobial properties. Hence, we aim to investigate the use of peanut skins as an antibacterial feed additive in the diets of broilers to prevent the proliferation of Salmonella Enteritidis (SE). One hundred sixty male hatchlings (Ross 308) were randomly assigned to, (1) PS: peanut skin diet without SE inoculation (2) PSSE: peanut skin diet and SE inoculation 3) CON: control diet without SE inoculation (4) CONSE: control diet with SE inoculation. Feed intake and body weights were determined at week 0 and 5. On days 10 and 24 post hatch, 3 birds/pen (24 total) from each treatment group were euthanized and the liver, spleen, small intestine, and ceca were collected. The weights of the liver, spleen and ceca were recorded. Organ invasion was determined by counting SE colonies. Each pen served as an experimental unit and was analyzed using a t-test. Performance data was analyzed in a completely randomized design using a general linear mixed model to evaluate differences. There were no significant differences ( P > 0.05) in weekly average pen body weight, total feed consumption, bird weight gain and feed conversion ratio between the treatment groups. There were no significant differences in SE CFU/g for fecal, litter or feed between treatment groups CONSE and PSSE. However, for both fecal and litter, the PSSE treatment group tended (P ≤0.1) to have a lower Salmonella CFU/g compared to the CONSE treatment group. The results indicate that peanut skins may have potential application as an antimicrobial feed additive to reduce the transmission or proliferation of SE in poultry environments or flocks.


2019 ◽  
Vol 17 (1) ◽  

Background: Commercial broiler is a rapidly growing sector in Bangladesh. The broilers are supplied with the balanced ration prepared from a number of ingredients which are not available uniformly throughout the years. On the other hands, manufactured feeds are costly and inconvenient for the rural farmers. This study is undertaken to use unconventional feed ingredients aiming to decrease the broiler production cost. Method: A total of ninety-nine day- old broiler chicks (Hubbard) of either sex were used in this study in 3 treatment groups to assess processed unconventional feed item (shoti, blood meal, poultry dropping and molasses) on growth and profitability upon rearing for 60 days. Broilers were reared in dip litter system and were fed ad libitum on conventional and unconventional diet dividing into 3 treatment diets namely, treatment diet 1 (T1: Conventional as control), treatment diet 2 (T2: unconventional with blood meal and shoti), and treatment diet 3 (T3: unconventional with blood meal, shoti, poultry droppings and molasses) throughout the trial period. Treatment group 1 (T1) was used as control. Results: Broilers fed on control diet (conventional feed) achieved higher (P<0.01) body weight, while the broilers offered diets with the highest amount of unconventional feed had the lowest body weight. Increased (P<0.01) feed intake was observed during 21days and 49 days of age when broilers fed diets with the supplementation, but no significant differences were found among the groups in terms of feed consumption during 33 day of age. FCR differed significantly (P<.01) throughout the trial period with the broilers fed diets without supplementation of unconventional feed item had the superior FCR than the others. Mortality rate was 6.06%,9.09%, and 9.09% in treatment group I, treatment group II, and treatment group III respectively while live weights, feed conversion and feed consumption was unaffected by all the dietary groups with/without incorporation of unconventional feed item up to day 60 days of age. Statistically significant (P<0.01) decreased live weight was observed among the treatment groups in 60-day-old birds. Productivity and cost-benefit analysis were performed. Conclusion: Use of unconventional feed ingredients in broiler production greatly reduces the feed cost with little hampering the growth rate and hence, it is profitable for the farmers.


Author(s):  
O. Merzlyakova ◽  
V. Rogachyev ◽  
V. Chegodaev

The efficiency of introducing probiotics based on strains of Bacillus subtilis, Bacillus licheniformis and their consortium in the amount of 150 g/t of feed into the diets of laying quails has been studied. The experiment lasting 182 days has been carried out on four groups of quails with 30 heads in each. The quails have been housed in the broiler battery in compliance with the required microclimate conditions. Quails of all groups have been received the main diet (compound feed) developed taking into account their age and physiological characteristics. The quails of the 1st, 2nd and 3rd experimental groups in addition to the main diet received probiotics (150 g/t compound feed) based on strains Bacillus subtilis, Bacillus licheniformis and their consortium, respectively. It has been found that feeding the laying quails of the consortium of strains Bacillus subtilis and Bacillus licheniformis had the most significant positive impact on their productive performance, it allowed to increase egg production by 7,81 %, egg laying intensity by 5,0 %, egg mass yield by 9,77 %, while reducing feed expenditures for 10 eggs by 13,35 %. The yield of hatching eggs has been increased by 7,03 %, hatchability of chickens from laid and fertilized eggs by 8,33 and 8,35 %, brooding waste decreased by 21,74 %. Hematological parameters of quails during the whole experiment were within the physiological norm. The economic effect calculated on the basis of data on the cost of compound feed, probiotics and the cost of sold eggs of quail laying was 14,56 % in the 3rd experimental group (in relation to the control group).


2020 ◽  
Vol 5 (2) ◽  
pp. 309-318
Author(s):  
Ihwan Ihwan ◽  
◽  
Rahmatia Rahmatia ◽  
Khildah Khaerati ◽  

Teratogenic is an abnormal development on embryo and is the cause of congenital defect or birth defect. This study aims to determine the effect of the addition of Dioscorea alata L. ethanol extracts to the embryo development on pregnant mice whose given orally to 24 mice which divided to 4 treatment groups, they are the normal group (NG) with NaCMC 0.5%; 28 mg/KgBB treatment group; 35 mg/KgBB; 42 mg/Kg BB. The addition of Dioscorea alata L ethanol extracts was done on the sixth day until the 15th day of pregnancy. On the 18th day of pregnancy, Laparaktomi was done to the pregnant mice and the embryo was taken out of the uterus. The observation was done to the fetus numbers, weight weighing of the fetus's body, dan length measurement of the fetus's body. Another observation is the observation of the external organ defect of the embryo. The study results that the addition of Dioscorea alata L ethanol extracts with various doses have no significant effect (P>0.5) to the mice external fetus development. On the examination of the fetus, we can conclude that Dioscorea alata L ethanol extracts don’t give any effect that may cause the defect of the fetus’ external organ.


2019 ◽  
Vol 8 (6) ◽  
pp. 823
Author(s):  
Hsiao-Fen Hsu ◽  
Chia-Chan Kao ◽  
Ti Lu ◽  
Jeremy C. Ying ◽  
Sheng-Yu Lee

The current study explored the differences in the effectiveness of first and second generation long-acting injections and orally administered antipsychotics in reducing the rehospitalization rate among patients with schizophrenia receiving home care services in a medical center in Southern Taiwan. Longitudinal data between 1 January 2006, and 31 December 2015, were collected retrospectively. Patients were classified into three treatment groups: First generation antipsychotic (FGA) long-acting injection (LAI), second generation antipsychotic long-acting injection (SGA) (LAI), and oral antipsychotics. The primary outcomes were the rehospitalization rate and the follow-up time (duration of receiving home care services) until psychiatric rehospitalization. A total of 78 patients with schizophrenia were recruited. The average observation time was about 40 months. The oral treatment group tended to be older with a higher number of female patients and a lower level of education. The FGA treatment group tended to have a higher frequency and duration of hospitalization before receiving home care services. We found no significant differences in the follow-up time or psychiatric rehospitalization rate after receiving home care services among the three treatment groups. We propose that oral and LAI antipsychotics were equally effective when patients received home care services. Our results can serve as a reference for the choice of treatment for patients with schizophrenia in a home care program.


1999 ◽  
Vol 1999 ◽  
pp. 176-176
Author(s):  
A.R. Peters ◽  
L.A. Dwyer ◽  
A. Dawson ◽  
P.A. Canham ◽  
J.D. Mackinnon

The problem of seasonal infertility in pigs has been recognised for many years. The infertility complex can may be manifested by increased returns to service, prolonged weaning to oestrus intervals and decreased litter size. The purpose of this trial was to evaluate the effects of Buserelin treatment on fertility in sows and gilts during the seasonally infertile period.A total of 1231 mixed parity sows and gilts from five outdoor herds in East Anglia were randomly assigned to one of three treatment groups. Any sows not presented for service at first post weaning oestrus were excluded. All sows and gilts judged to be in adequate health and condition to be kept in a commercial breeding herd were included. Group C sows and gilts were given no treatment. Group R1 sows and gilts were injected i.m. with 8μg Buserelin (2.0ml Receptal; Hoechst Roussel Vet UK Ltd) on the day of service.


Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1581
Author(s):  
Artur Rybarczyk ◽  
Elżbieta Bogusławska-Wąs ◽  
Alicja Dłubała

The objective of the study was to determine the effects of probiotic bacteria Bacillus licheniformis and Bacillus subtilis on microbiological properties of feed mixtures and on the digestive tract content as applicable to production traits and carcass characteristics of fatteners. The experiment was performed on 83,838 fatteners from four successive (insertions) productions in two groups. From the seventy eighth day of age till marketing to the slaughter plant, the pigs were supplied with BioPlus YC probiotic (Chr. Hansen) in the amount of 400 g/t. The preparation contained a complex of probiotic bacteria Bacillus licheniformis DSM 5749, and Bacillus subtilis DSM 5750 spores in a 1:1 ratio. From the fourth insertion, after reaching a body weight of approximately 112 kg, 60 fatteners were selected from each group to measure carcass quality and half of them for meat quality evaluation. Moreover, microbiological analyses in feed and colon were performed. The study showed that BioPlus YC probiotics supplementation resulted in a significantly higher count of B. subtilis and B. licheniformis in the feed, a higher count of B. subtilis, B. licheniformis and LAB, as well as a lower count of Enterobacteriaceae, Enterococcus, Clostridium and Bacillus sp. in the mucosa and in the colorectal content of the test pigs. Our work has shown that supplementation with the BioPlus YC probiotic had a positive effect on the production traits of pigs mainly by reducing mortality (2.83%, p = 0.010), lowering feed conversion ratio—FCR (2.59 kg/kg, p = 0.013), better average daily gain—ADG (0.95 kg/day, p = 0.002) and shorter fattening period (77.25 days, p = 0.019) when compared to the control group (4.19%; 2.79 kg/kg; 0.89 kg/day; 92.8 days, respectively). The addition of the specific Bacillus bacteria did not influence carcass and meat characteristics of the test fatteners.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 137-138
Author(s):  
Morgan T Thayer ◽  
Jacob A Richert ◽  
Karissa N Rulon ◽  
Matthew D Asmus ◽  
Daniel B Jones ◽  
...  

Abstract Forty-seven sows and their progeny were used to determine if feeding gestating and lactating sows a Bacillus licheniformis direct-fed microbial (DFM), an organic acid blend of medium chain and short chain fatty acids (OA), or in combination improves sow lactation feed and water intake, litter growth, and subsequent reproductive performance. On approximately d80 of gestation, sows were fed one of four diets in a 2 x 2 factorial design: 1) gestation control (CON; 0.55% SID Lysine), 2) CON with DFM (1.6x109 CFU/kg of complete feed), 3) CON with 0.4% OA, 4) CON with both DFM and OA. Dietary treatments were also fed throughout lactation (1.00% SID Lysine) starting on approximately d112 of gestation when sows entered farrowing facility. There was a tendency (P = 0.079) for DFM to decrease the amount of sow body weight loss in lactation by approximately 6% compared to sows not consuming the DFM, likely related to DFM sows numerically (P = 0.124) consuming 8.4% more feed during d7-14 of lactation. Sows fed the OA diets had fewer mummies/litter (P = 0.038) compared to diets not containing OA. Sows fed diets with the DFM gave birth to lighter pigs born alive (P = 0.003) compared to non-DFM fed sows, and a tendency for an interaction (P = 0.092) existed where feeding OA+DFM lessened the decrease in born alive BW. There was an interaction tendency (P = 0.133) where sows fed DFM returned to estrus 22 hours sooner than CON, but only 8 hours sooner when sows were fed the OA+DFM diet. In conclusion, feeding a Bacillus licheniformis DFM to sows may decrease pig born alive weight but reduce sow BW loss through 6.4% more lactation feed intake, quickening the return to estrus. Feeding the OA alone or in combination did not improve sow reproductive and litter growth performance in this study, and may require a larger sample size.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 347-348
Author(s):  
Kelsey Schubach ◽  
Bruno I Cappellozza ◽  
Marcos Renato Burim ◽  
André Velasco ◽  
Fernando Sagrado ◽  
...  

Abstract Alternatives that alleviate stress-related responses and improve performance of the beef cattle herd are imperative and deserve further investigation. In previous trials, administration of the bovine appeasing substance (BAS) has improved performance of newly-weaned and feedlot received beef animals, as well as reduced the risk of dark, firm, and dry (DFD) cuts in carcass obtained from Bos indicus cattle. Therefore, this study was designed to evaluate the effects of BAS administration at castration on pre-conditioning performance of crossbred beef animals. On day 0, 390 crossbred Angus × Nellore animals were ranked by initial shrunk BW (255 ± 21.1 kg) and assigned to receive or not (CON) 5 mL/head of BAS (SecureCattle; Nutricorp, Araras, SP, Brazil) immediately before castration. From d 0 to 30, animals within treatments were maintained in 2 feedot pens with a minimum distance (300 m) to avoid contact between treatment groups and received a grass hay-based diet (70:30 roughage:concentrate ratio) ad libitum. On day 30, animals were individually weighed following 16 hours of feed and water restriction. Hence, a descriptive analysis was performed to evaluate pen dry matter intake (DMI) and feed efficiency (FE). Animal was considered the experimental unit and all data were analyzed using the PROC MIXED procedure of SAS (version 9.4; SAS Inst. Inc., Cary, NC). Bovine appeasing substance administration at castration improved ADG and BW change (P &lt; 0.0001) compared with CON cohorts (0.983 vs. 1.155 kg/d and 29.5 vs. 34.6 kg for ADG and BW change, respectively). Total DMI was similar among treatments when reported as kg/d (6.70 vs. 6.75 kg) or % of BW (2.48 vs. 2.48%), whereas FE was dramatically improved in BAS-administered animals (146 vs. 172 g/kg for CON and BAS, respectively). In summary, BAS administration improved performance of crossbred beef animals for 30 days post-castration.


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