Lower Fatigue in Fit and Positive Women with Fibromyalgia: The al-Ándalus Project

Pain Medicine ◽  
2019 ◽  
Vol 20 (12) ◽  
pp. 2506-2515 ◽  
Author(s):  
Fernando Estévez-López ◽  
María Rodriguez-Ayllon ◽  
Alberto Soriano-Maldonado ◽  
Pedro Acosta-Manzano ◽  
Víctor Segura-Jiménez ◽  
...  

Abstract Objective To analyze 1) the independent association of physical fitness, positive affect, and negative affect with the different dimensions of fatigue (general fatigue, physical fatigue, reduced activity, reduced motivation, and mental fatigue) and 2) whether the interactions of physical fitness, positive affect, and negative affect were associated with fatigue over and above the independent association. Design Cross-sectional study in 420 women with fibromyalgia. Setting Fibromyalgia associations from southern Spain. Methods Physical fitness was measured by performance-based tests, and questionnaires were used to measure positive affect, negative affect, and different dimensions of fatigue (general fatigue, physical fatigue, reduced activity, reduced motivation, and mental fatigue). Age, body mass index, and current pain level were included as potential confounders in all analyses. Results Physical fitness was independently associated with general fatigue, physical fatigue, and reduced activity (all P ≤ 0.02). Positive affect was independently associated with all fatigue dimensions (all P < 0.001). Negative affect was independently associated with general fatigue, physical fatigue, reduced motivation, and mental fatigue (all P ≤ 0.04). The interaction of overall physical fitness and positive affect was related to general fatigue and physical fatigue (all P ≤ 0.02). Women with fibromyalgia with higher levels of overall physical fitness and positive affect showed the lowest general fatigue and physical fatigue. Conclusions In women with fibromyalgia, positive affect was independently and consistently associated with all dimensions of fatigue. The combination of higher levels of overall physical fitness and positive affect might serve as a buffer against general and physical fatigue in women with fibromyalgia.

2019 ◽  
Vol 7 (1) ◽  
pp. 77-85 ◽  
Author(s):  
Sophie D van der Linden ◽  
Karin Gehring ◽  
Geert-Jan M Rutten ◽  
Willem J Kop ◽  
Margriet M Sitskoorn

Abstract Background Fatigue is a common symptom in patients with brain tumors, but comprehensive studies on fatigue in patients with meningioma specifically are lacking. This study examined the prevalence and correlates of fatigue in meningioma patients. Methods Patients with grade I meningioma completed the Multidimensional Fatigue Inventory (MFI-20) before and 1 year after neurosurgery. The MFI consists of 5 subscales: General Fatigue, Physical Fatigue, Mental Fatigue, Reduced Motivation, and Reduced Activity. Patients’ scores were compared with normative data. Preoperative fatigue was compared with postoperative fatigue. Correlations with sex, age, education, tumor hemisphere, preoperative tumor volume, antiepileptic drugs (AEDs), symptoms of anxiety/depression, and self-reported cognitive complaints were explored. Results Questionnaires were completed by 65 patients preoperatively, and 53 patients postoperatively. Of 34 patients, data from both time points were available. Patients had significantly higher fatigue levels on all subscales compared to normative values at both time points. Mean scores on General Fatigue, Physical Fatigue, and Mental Fatigue remained stable over time and improvements were observed on Reduced Motivation and Reduced Activity. Preoperatively, the prevalence of high fatigue (Z-score ≥ 1.3) varied between 34% for Reduced Motivation and 43% for General Fatigue/Mental Fatigue. The postoperative prevalence ranged from 19% for Reduced Activity to 49% on Mental Fatigue. Fatigue was associated with cognitive complaints, anxiety and depression, but not with education, tumor lateralization, tumor volume, or AEDs. Conclusion Fatigue is a common and persistent symptom in patients with meningioma undergoing neurosurgery. Findings emphasize the need for more research and appropriate care targeting fatigue for meningioma patients.


2021 ◽  
Author(s):  
Dandan Zhang ◽  
Qian Wu ◽  
Xixi Gu ◽  
Zhifeng Gu ◽  
Chen Dong ◽  
...  

Abstract Purpose Few studies have assessed fatigue of meningioma patients. The purpose of this study was to explore the prevalence, severity, and risk factors of multidimensional fatigue, as well as the impact on health-related quality of life (HRQoL) in Chinese meningioma patients newly diagnosed. Methods This cross-sectional study included 120 Chinese meningioma patients recruited from Affiliated Hospital of Nantong University from January 2020 to February 2021. Data were collected before surgery, including demographic, clinical and psychological characteristics, as well as fatigue scores, based on completion of the Multidimensional Fatigue Inventory (MFI-20). Spearman correlation and multiple linear regression were used to analyze the data. Results The results demonstrated that a high prevalence of severe fatigue for each dimension: general fatigue (33.3%), physical fatigue (27.5%), reduced activity (28.3%), reduced motivation (12.5%), mental fatigue (11.7%), and total fatigue (23.3%). Headache and anxiety were predictors of general fatigue. Depression was an independent predictor of physical fatigue. Karnofsky Performance Status (KPS) score and depression independently predicted reduced activity. Depression and Epworth Sleepiness Scale (ESS) score were risk factors predicting reduced motivation, while KPS score and anxiety predicted mental fatigue. Importantly, comorbidity, KPS score, headache, depression, sleep disturbances, and ESS score could predict total fatigue. Furthermore, MFI-20 scores in all dimensions were negatively correlated with Short Form 36 Health Survey (SF-36) scores in all dimensions. Conclusion Our findings indicate that meningioma patients newly diagnosed are frequently affected by fatigue, potentially contributing to impair HRQoL. For patients with risk factors of fatigue, targeted interventions are advised in order to decrease fatigue and improve HRQoL.


2021 ◽  
Author(s):  
Dandan Zhang ◽  
Qian Wu ◽  
Xixi Gu ◽  
Zhifeng Gu ◽  
Chen Dong ◽  
...  

Abstract Purpose Few studies have assessed fatigue of meningioma patients. The purpose of this study was to explore the prevalence, severity, and risk factors of multidimensional fatigue, as well as the impact on health-related quality of life (HRQoL) in Chinese meningioma patients newly diagnosed. Methods This cross-sectional study included 120 Chinese meningioma patients recruited from Affiliated Hospital of Nantong University from January 2020 to February 2021. Data were collected before surgery, including demographic, clinical and psychological characteristics, as well as fatigue scores, based on completion of the Multidimensional Fatigue Inventory (MFI-20). Spearman correlation and multiple linear regression were used to analyze the data. Results The results demonstrated that a high prevalence of severe fatigue for each dimension: general fatigue (33.3%), physical fatigue (27.5%), reduced activity (28.3%), reduced motivation (12.5%), mental fatigue (11.7%), and total fatigue (23.3%). Headache and anxiety were predictors of general fatigue. Depression was an independent predictor of physical fatigue. Karnofsky Performance Status (KPS) score and depression independently predicted reduced activity. Depression and Epworth Sleepiness Scale (ESS) score were risk factors predicting reduced motivation, while KPS score and anxiety predicted mental fatigue. Importantly, comorbidity, KPS score, headache, depression, sleep disturbances, and ESS score could predict total fatigue. Furthermore, MFI-20 scores in all dimensions were negatively correlated with Short Form 36 Health Survey (SF-36) scores in all dimensions. Conclusion Our findings indicate that meningioma patients newly diagnosed are frequently affected by fatigue, potentially contributing to impair HRQoL. For patients with risk factors of fatigue, targeted interventions are advised in order to decrease fatigue and improve HRQoL.


2018 ◽  
Vol 4 (1) ◽  
pp. 00079-2017 ◽  
Author(s):  
Todd M. Tartavoulle ◽  
Aryn C. Karpinski ◽  
Andrew Aubin ◽  
Benzi M. Kluger ◽  
Oliver Distler ◽  
...  

Pulmonary hypertension is a potentially fatal disease. Despite pharmacological advances in pulmonary hypertension, fatigue remains common in patients with pulmonary hypertension.A convenience sample of 120 participants at an international patient conference completed the Multidimensional Fatigue Inventory (MFI)-20 scale. Data on New York Heart Association Functional Class, body mass index, oxygen use and medication type/use were also collected.There was a high prevalence of “severe” to “very severe” fatigue for each dimension: General Fatigue (60%), Physical Fatigue (55.8%), Reduced Activity (41.7%), Reduced Motivation (32.5%) and Mental Fatigue (27.5%). The mean±sd overall MFI-20 score was 58±5.1. Dimensions with the highest averaged levels were General Fatigue (13.40±3.61), Physical Fatigue (13.23±3.67) and Reduced Activity (11.33±4.16). Body mass index correlated with higher fatigue scores. Phosphodiesterase inhibitor plus endothelin receptor antagonist combination negatively predicted General Fatigue, Physical Fatigue, Reduced Motivation and Reduced Activity. Triple therapy was a significant predictor of General Fatigue, Physical Fatigue and Reduced Activity. There were no significant predictors of Mental Fatigue.Multidimensional fatigue is common and severe in patients with pulmonary hypertension. Phosphodiesterase inhibitor plus endothelin receptor antagonist combination resulted in lower scores in most fatigue dimensions. Comprehensive assessment of fatigue should be considered in the clinical care of patients with pulmonary hypertension and clinical research to develop formal interventions that target this disabling symptom.


2017 ◽  
Vol 14 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Ivan S.K. Thong ◽  
Gabriel Tan ◽  
Mark P. Jensen

AbstractObjectivesChronic pain is a significant problem worldwide and is associated with significant elevations in negative affect, depressive symptoms, sleep problems, and physical dysfunction. Positive affect could potentially buffer the impact of pain on patient functioning. If it does, then positive affect could be directly targeted in treatment to benefit individuals with chronic pain. The purpose of this study was to test for such moderating effects.MethodsThis was a cross-sectional study, we administered measures of pain intensity, depressive symptoms, sleep problems, pain interference, and positive and negative affect to 100 individuals with chronic back or knee pain in a single face-to-face assessment session.ResultsThe associations between pain intensity and negative affect, and between pain intensity and depressive symptoms were moderated by positive affect. This moderation effect was explained by the fact that participants with low positive affect evidenced strong associations between pain intensity and both depression and negative affect; participants with high positive affect, on the other hand, evidenced weak and non-significant associations between pain intensity and both depression and negative affect. Positive affect did not moderate the associations between pain intensity and either sleep problems or pain interference.ConclusionThe findings are consistent with the possibility that positive affect may buffer the impact of pain intensity on negative affect and depressive symptoms. Longitudinal and experimental research is needed to determine the potential benefits of treatments that increase positive affect on negative affect and depressive symptoms in chronic pain populations.ImplicationsThe study findings suggest the possibility that “positive psychology” interventions which increase positive affect could benefit individuals with chronic pain by reducing the impact of pain on negative outcomes. Research to test this possibility is warranted.


2003 ◽  
Vol 11 (2) ◽  
pp. 265-274 ◽  
Author(s):  
Glenn V. Ostir ◽  
Jiska Cohen-Mansfield ◽  
Suzanne Leveille ◽  
Stefano Volpato ◽  
Jack M. Guralnik

This study investigated whether positive or negative affect has an independent association with exercise self-efficacy. Participants (N= 324) age 75-85 were classified as high or at-risk performers, and three exercise-self-efficacy items (scored 1-10) were assessed. For at-risk performers, positive affect was significantly associated with confidence in the ability to perform strength and flexibility (b= 0.83,SE= 0.23,p= .001) and aerobic exercise (b= 0.59,SE= 0.28,p= .04) and with the perception that exercise would not worsen preexisting symptoms (b= 0.73,SE= 0.24,p= .001). Among high performers, nonsignificant associations were found for positive and negative affect and exercise-self-efficacy. For at-risk performers, higher positive affect was associated with an increased odds ratio of 2.72 for scoring 10 on the muscle strength and flexibility item, 4.08 on the aerobic item, and 2.94 on the item assessing preexisting symptoms. The results suggest that improving at-risk older adults’ positive affect might increase their participation in exercise.


2021 ◽  
Author(s):  
Sanne Preuter ◽  
Bastian Jaeger ◽  
Marielle Stel

Deceiving others is generally viewed as immoral. However, most people lie on a daily basis. This paper examines the psychological consequences for the liars themselves, as they are participating in what is generally perceived as immoral behavior. More specifically, this paper focuses on the effects of self-centered and other-oriented lying on the liar’s self-esteem and affect. We tested 1) if lying, in comparison to telling the truth, lowers liars’ self-esteem and positive affect and 2) if these effects are stronger for self-centered than other-oriented lying, as self-centered lying is generally seen as more immoral. In total, three cross-sectional and one longitudinal studies were conducted (N = 783). Results showed that lying decreased people’s self-esteem and increased negative affect, regardless of the type of lie. Furthermore, lying on a given day decreased people’s self-esteem compared to their self-esteem on the previous day and to their average level of self-esteem.


2021 ◽  
Vol 12 ◽  
Author(s):  
Gregory N. Bratman ◽  
Gerald Young ◽  
Ashish Mehta ◽  
Ihno Lee Babineaux ◽  
Gretchen C. Daily ◽  
...  

Mounting evidence shows that nature contact is associated with affective benefits. However, the psychological mechanisms responsible for these effects are not well understood. In this study, we examined whether more time spent in nature was associated with higher levels of positive affect in general, and lower levels of negative affect and rumination in general. We also conducted a cross-sectional mediation analysis to examine whether rumination mediated the association of nature contact with affect. Participants (N = 617) reported their average time spent in nature each week, as well as their general levels of positive and negative affect, and the degree to which they typically engaged in rumination in daily life. We then used structural equation modeling to test our hypotheses. Our results support the hypothesis that nature contact is associated with general levels of affect, and that rumination mediates this association for negative affect, and marginally mediates this association for positive affect.


2009 ◽  
Vol 7 (2) ◽  
pp. 207-211 ◽  
Author(s):  
Maria E. Carlsson

ABSTRACTObjectives:The relatives’ burdens in palliative care are considerable and may cause fatigue. The overall aim of this study was to gain a greater understanding of fatigue in relatives of patients cared for in palliative care settings.Methods:This study has a descriptive, comparative, and cross-sectional design. The sample consisted of relatives of all patients cared for in palliative care settings in Uppsala County during a specific day. Relatives completed a questionnaire consisting of the Multidimensional Fatique Inventory (MFI-20) and questions from the Karolinska Sleepiness Scale (KSS) and Karolinska Sleep questionnaire (KSQ).Results:Relatives (n = 56) scored high on every dimension on the MFI-20 scale. Two significant negative correlations were found to exist between age and fatigue, with younger relatives reporting more mental fatigue (p < .01) and more reduced activity (p < .01) than older relatives. Relatives of patients in institutional care had higher values concerning mental fatigue (p < .01) and reduced motivation (p < .05). Relatives of mostly bedridden patients were significantly more tired but did not have significantly less motivation than relatives of mostly ambulatory patients.Significance of results:The findings imply that fatigue is highly prevalent in relatives of patients in palliative care. The sample in this study scored higher in comparison with norm values and also in comparison with relatives of patients with end-stage renal disease. Their scores were similar to those of cancer patients undergoing radiotherapy.


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