Epidemiological and Biochemical Factors (Serum Ferritin and Vitamin D) Associated with Premature Graying Of Hair

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Nawres taher Alrgig ◽  
Nermeen Samy Abdel Fattah ◽  
Rania Mahmoud Elhusseiny
Keyword(s):  
Vitamin D ◽  
Serum Ferritin ◽  
Life Style ◽  
Serum Levels ◽  
Stressful Events ◽  
Stress Perception ◽  
Significant Difference ◽  
Sedentary Life ◽  
Sex Assessment ◽  
Sedentary Life Style

Abstract Background Premature graying of hair (PHG) is defined as graying of hair before the age of 20 years in Caucasians and before 30 years in Blacks. Several factors contribute to development of hair graying as genetics, environmental factors, life style and stressful events. Also, many biological markers were associated with development of hair graying as vitamin D, ferritin, vitamin B12 and many other electrolytes as calcium and magnesium. Aim of the study assess various epidemiological factors and biochemical variables (serum ferritin and vitamin D) associated with premature graying of hair. Patients and methods The current study included 75 premature hair graying patients, and 75 apparently healthy controls of matched age and sex. Assessment of epidemiological, clinical characteristics, estimation of serum levels of vitamin D and ferritin was done for included subjects. Results We detected positive correlation of sedentary life style, stress perception and family history with PHG development. No significant difference of vitamin D between the two groups, while low serum ferritin was significantly associated with PHG patients.

scholarly journals Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255335
Author(s):  
Melanie Ricke-Hoch ◽  
Elisabeth Stelling ◽  
Lisa Lasswitz ◽  
Antonia P. Gunesch ◽  
Martina Kasten ◽  
...  
Keyword(s):  
Prostaglandin E2 ◽  
B Cell ◽  
Life Style ◽  
Severe Disease ◽  
Serum Levels ◽  
Regular Exercise ◽  
Sedentary Life ◽  
Male Sex ◽  
Cox 2 ◽  
Sedentary Life Style

The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The present study finds that risk-factors for severe COVID-19 disease courses, i.e. male sex, older age and sedentary life style are associated with higher prostaglandin E2 (PGE2) serum levels in blood samples from unaffected subjects. In COVID-19 patients, PGE2 blood levels are markedly elevated and correlate positively with disease severity. SARS-CoV-2 induces PGE2 generation and secretion in infected lung epithelial cells by upregulating cyclo-oxygenase (COX)-2 and reducing the PG-degrading enzyme 15-hydroxyprostaglandin-dehydrogenase. Also living human precision cut lung slices (PCLS) infected with SARS-CoV-2 display upregulated COX-2. Regular exercise in aged individuals lowers PGE2 serum levels, which leads to increased Paired-Box-Protein-Pax-5 (PAX5) expression, a master regulator of B-cell survival, proliferation and differentiation also towards long lived memory B-cells, in human pre-B-cell lines. Moreover, PGE2 levels in serum of COVID-19 patients lowers the expression of PAX5 in human pre-B-cell lines. The PGE2 inhibitor Taxifolin reduces SARS-CoV-2-induced PGE2 production. In conclusion, SARS-CoV-2, male sex, old age, and sedentary life style increase PGE2 levels, which may reduce the early anti-viral defense as well as the development of immunity promoting severe disease courses and multiple infections. Regular exercise and Taxifolin treatment may reduce these risks and prevent severe disease courses.

scholarly journals Investigation of communication levels of university students doing sports and do not sportSpor yapan ve yapmayan üniversite öğrencilerinin iletişim düzeylerinin incelenmesi

2017 ◽  
Vol 14 (3) ◽  
pp. 2317
Author(s):  
Hasan Ulukan ◽  
Alper Kartal ◽  
Serkan Zengin ◽  
Engin Abanoz ◽  
Necmettin Parlak
Keyword(s):  
University Students ◽  
Communication Skills ◽  
Life Style ◽  
Male Students ◽  
Science Literature ◽  
Significant Difference ◽  
Package Program ◽  
Sedentary Life ◽  
Sedentary Life Style ◽  
Age Range

In the study conducted, it was aimed to examine the communication levels of university students doing sports and having sedentary life style. The study universe of the study consisted of  304 students in total of which 124 female students and 180 male students of Adnan Menderes University in 2015- 2016 education year.  Students having the habit of doing sports regularly were selected from  School of Physical Education and Sports and students having sedentary life style were selected  from Faculty of Communication and Faculty of Science- Literature. ''Scale for Evaluation of the Communication Skills'' was used in the determination of communication skills of the participants. Mann Whitney U test and Kruskal Wallis H Test  in SPSS 22.0 package program were utilized for statistical analysis of the data collected. At the end of the study, it was found that communication skills levels of students having the habit of doing sports regularly and students having sedentary life style did not show statistically significant difference according to gender, age range, status of doing sports regularly, place of living and type of high school graduated from (p>0.05). As a result, it can be said that socio-demographical features has no significant affect on communication skills.of students having the habit of doing sports regularly and students having sedentary life style.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetYapılan bu araştırmada spor yapan ve yapmayan üniversite öğrencilerinin iletişim düzeylerinin incelenmesi amaçlanmıştır. Araştırmaya 2015-2016 eğitim ve öğretim yılında Adnan Menderes Üniversitesi öğrencisi olan 124 kadın ve 180 erkek olmak üzere toplam 304 üniversite öğrencisi dâhil edilmiştir. Düzenli olarak spor yapma alışkanlığı bulunan öğrenciler Beden Eğitimi ve Spor Yüksekokulu’nda öğrenim gören öğrencilerden, spor yapma alışkanlığı bulunmayan öğrenciler ise İletişim Fakültesi ile Fen Edebiyat Fakültesi öğrencilerinden seçilmiştir. Araştırmaya katılan öğrencilerin iletişim becerilerinin tespit edilmesinde “İletişim Becerilerini Değerlendirme Ölçeği” kullanılmıştır. Araştırmada elde edilen verilerin istatistiksel analizlerinde SPSS 22.0 veri analiz programında Mann Whitney U analizi ile Kruskal Wallis H analizinden yararlanılmıştır. Araştırmanın sonunda spor yapma alışkanlığı bulunan ve bulunmayan üniversite öğrencilerinin sahip oldukları iletişim becerilerinin cinsiyet, yaş grubu, düzenli spor yapma durumu, yaşamlarının büyük çoğunluğunun geçtiği yerleşim yeri ve mezun oldukları lise türüne göre istatistiksel açıdan anlamlı farklılık göstermediği tespit edilmiştir (p>0.05). Sonuç olarak, düzenli olarak spor yapma alışkanlığı bulunan ve bulunmayan öğrencilerde sosyo-demografik özelliklerin iletişim becerisini etkilemediği söylenebilir.

Role of Panchakarma in the management of Hypothyroidism

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Dr.Suraj Kumbar ◽  
Dr.Lohith BA ◽  
Dr.Ashvinikumar M ◽  
Dr. Amritha R ◽  
Dr. Shameem Banu
Keyword(s):  
Metabolic Rate ◽  
Pituitary Gland ◽  
Life Style ◽  
The Body ◽  
Management Guidelines ◽  
Quality Of Food ◽  
Sedentary Life ◽  
Sedentary Life Style

We are in technical era where there is more of sedentary life style and stress along with this urbanization is affecting our quality of food and health. This is leading to many lifestyle disorders and hormonal imbalances in our body. Hypothyroidism one among the endocrinal disorder. Thyroid is an endocrinal gland secrets T3 and T4 hormones regulated by TSH which is secreted by Pituitary gland. These hormones have two major effects on the body, 1) To increase the overall metabolic rate in the body 2) To stimulate growth in children. Hypothyroidism is common health issue in India. The highest prevalence of hypothyroidism (13.1%) is noted in people aged 46-54yrs old. With people aged 18-35 yrs being less affected (7.5%). To prevent these hazards Panchakarma is beneficiary to maintain metabolic rate. Here an attempt is made to diagnose hypothyroidism in the light of Ayurveda and management guidelines through Panchakarma.

scholarly journals Role of vitamin D serum levels in prevention of primary and recurrent melanoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Lombardo ◽  
A. Vigezzi ◽  
G. Ietto ◽  
C. Franchi ◽  
V. Iori ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Levels ◽  
Mitotic Rate ◽  
Control Group ◽  
Healthy Population ◽  
Histological Subtype ◽  
Melanoma Diagnosis ◽  
Significant Difference ◽  
Tumour Location

AbstractPatients afflicted with melanoma show lower vitamin D serum levels (VDSL) than the healthy population. This hypothesis agrees with its well-known antiproliferative features. An observational study was carried out to collect VDSL in patients suffering from melanoma. Our aim was to identify a potential connection between low VDSL and the risk to incur melanoma. Furthermore, we studied the association between VDSL at the diagnosis of melanoma and other germane prognostic factors. The population held in regard was composed of 154 patients with a diagnosis of melanoma between 2016 and 2019. These patients were retrospectively collected from our follow-up storage. We compared VDSL to clinical and pathological parameters (age, sex, tumour location, Breslow’s depth, Clark’s level, histological subtype, ulceration, et aliqua). Moreover, we recruited a control group with negative melanoma history. Mean and median of VDSL were significantly lower in the melanoma group. Instead, we found a negative association between melanoma and VDSL > 30 ng/L (OR 0.11; p < 0.0001). No correlation between VDSL and both Breslow’s depth and Clark’s level was discovered, but the VDSL comparison between thin (depth ≤ 1 mm) and thick tumours (depth > 1 mm) revealed a statistically significant difference (21.1 ± 8.2 ng/L vs 17.8 ± 8.1; p = 0.01). Moreover, VDSL were significantly lower in melanomas with mitotic rate ≥ 1/mm2 (22.1 ± 8.3 ng/L; p < 0007). Nevertheless, no connection was found between VDSL and both ulceration and positive sentinel nodes (p = 0.76; p = 0.74). Besides, our study revealed no association between VDSL and histological subtype (p = 0.161). Lower VDSL correlate with thick and high mitotic rate tumours. Future prospective studies would investigate if appropriate upkeep of suitable VDSL can decrease the risk of primary and recurrent melanoma diagnosis.

scholarly journals A Comparison of Lipid Profile Between Sedentary and Non Sedentary Workers

1970 ◽  
Vol 22 (1) ◽  
pp. 10-14
Author(s):  
Iftekhar Mahmood ◽  
MM Rahman Khan ◽  
M Khalilur Rahman ◽  
MM Hoque Chowdhury
Keyword(s):  
Cardiovascular Disease ◽  
Life Style ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Epidemiological Studies ◽  
Control Group ◽  
Age Group ◽  
Sedentary Life ◽  
Bank Employees ◽  
Sedentary Life Style

In different epidemiological studies, an association between sedentary life style and incidence of cardiovascular diseases has been demonstrated. Dyslipidaemia is one of the important risk factors of cardiovascular disease. An association of dyslipidaemia with sedentary life style has been considered. This study was carried out among 50 sedentary workers (teachers, office staffs, bank employees) at Pabna District and 50 individuals with non-sedentary jobs matched for age group and sex for the control group to see the association. Body mass index (BMI), blood pressure (BP), plasma level of glucose, total cholesterol, low density lipoprotein (LDL), and triglycerides (Tgs) were found to be significantly higher whereas high density lipoprotein (HDL) was found to be significantly lower among the sedentary workers as compared with the control subjects. From the study, it appears that dyslipidaemia is more common in sedentary workers and the relative risk for cardiovascular disease is increased among them due to the sedentary nature of their jobs. DOI: 10.3329/taj.v22i1.5014 TAJ 2009; 22(1): 10-14

Prevalence of Hypertension and Associated Factors among Bank Workers in Harar Town, Eastern Ethiopia 2018

2020 ◽  
Vol 2 (3) ◽  
pp. 1-6
Author(s):  
Gosaye Teklehaymanot Zewde ◽  
Keyword(s):  
Risk Factor ◽  
Heart Disease ◽  
Life Style ◽  
Associated Factors ◽  
Study Participant ◽  
P Value ◽  
Eastern Ethiopia ◽  
Sedentary Life ◽  
Sedentary Life Style

Background: Hypertension clinically defined as a blood pressure of 140/90 mmHg or more on at least two readings on separated time. It is one of the most prevalent non communicable diseases and the most important preventable risk factor for premature death worldwide, due to heart disease and stroke. It is the most important modifiable risk factor for coronary heart disease, stroke, congestive heart failure, end stage renal disease and peripheral vascular diseases. Objective: To assess the prevalence of hypertension and its associated factors among bank workers in Harar town, Eastern Ethiopia 2018. Methods and material: Institutions based cross sectional study was conducted on 149 Bank workers in 6 governmental and 19 private banks which were found in Harar Town. Sample was allocated proportionately and study participant was selected by simple random sampling. Collected and checked data were entered in to Epi Data software version 3.02 and exported and analyzed using SPSS version 21. Descriptive statistics were used to determine prevalence such as frequency, percentage, mean and ratio. Both Bivariate and multiple logistic regressions were used to observe the association between the outcome variable and associated factors. P value less than 0.2 in Bivariate analysis was transferred to multivariate analysis and P value less than or equal to 0.05 was considered as level of statistically significance. Result: The prevalence of hypertension on this study was 27.5 %. Among study participant 6(4%) had diagnosed with hypertension and only 3 (2%) had on treatment and follow- up. 26(17.4%) bank workers BMI Was obsessed. In multivariable logistic regression analysis Age, Sedentary life style and BMI of bank workers had significant association with hypertension. Conclusion and recommendation: The prevalence of Hypertension in the study was 27.5% Age, Sedentary life style and BMI (Obesity) in this study was positively associated with higher odds of having hypertension. Regular blood monitoring, conducting physical exercise and reduction of Alcohol consumption and street Treatment care and follow-up strategy need to be maintained.

Review of concept of vihara with special reference to viharaja hetu of amlapitta.

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Ranibala Nemade
Keyword(s):  
Special Reference ◽  
Present Article ◽  
Life Style ◽  
Food Culture ◽  
Modern World ◽  
Great Contribution ◽  
Common Diseases ◽  
Equal Importance ◽  
Sedentary Life ◽  
Sedentary Life Style

The modern world is currently facing an epidemic of life style related diseases as a result of improper diet,sedentary life style and stress.Ayurveda has great contribution in prevention of the diseases as well as treatment of diseases.Ayurveda has given equal importance to Ahara and Vihara.All types of activities are included in Vihara.Vihara is a very broad concept.It has a key role in Swasthavrutta,Nidana and Chikitsa.The present article mainly focuses on the Nidana (Hetu-reason) aspect of Vihara as the Nidana Parivarjana is the prime treatment of any disease. Modern era’s changing lifestyle along with changing food culture has given birth to various diseases.Amlapitta is one of the most common diseases seen in the society.The disease Amlapitta is not directly mentioned in Bruhatrayi.Acharya Kashaypa was the first to describe Amlapitta as a disease.Viharaja  Hetu play important role in the pathogenesis of Amlapitta.

scholarly journals The levels of serum vitamin D and ferritn in Korean women with obesity and severe obesity

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Nan-Hee Kang ◽  
Ha-Neul Choi ◽  
Jung-Eun Yim
Keyword(s):  
Vitamin D ◽  
Serum Ferritin ◽  
Severe Obesity ◽  
Eating Habits ◽  
Serum Vitamin ◽  
Obese Group ◽  
Korean Women ◽  
Serum Vitamin D ◽  
Significant Difference ◽  
Severely Obese

AbstractIntroductionIn Korean women, the prevalence rate of severe obesity (BMI ≥ 30.0 kg/m2) increased from 2.8% in 2005 to 4.7% in 2015. It is reported that clinically severe obesity has more serious health problems than moderate obesity and creates additional challenges. Vitamin D was suggested a beneficial effect on inflammatory response, but serum ferritin was has been known as a biomarker of inflammation. The objective of this study is to compare the levels of vitamin D and ferritin in Korean women with moderate and severe obesity.Materials and Methods44 Korean women with obese and severely obese were recruited. The participants were classified as obese (BMI 25.0–29.9 kg/m2, n = 23) and severely obese (BMI ≥ 30.0 kg/m2, n = 21) group. The informed clinical data, including general information, anthropometric data, body composition, and blood analysis results, were obtained from the participants. Serum vitamin D [25(OH)D3] and ferritin were measured. Statistical analyses were performed using the SPSS Statistics for Windows version 24.0.ResultsThere was a difference in eating habits, severely obese group ate more irregularly and consumed more snacks than obese group. The levels of alanine aminotransferase, aspartate aminotransferase, hemoglobin Alc, total cholesterol, and triglyceride were not significantly different in obese and severely obese group. And, the levels of serum 25(OH)D3 and ferritin were almost normal and there was no significant difference between the two groups.ConclusionThis study showed that there is a difference in eating habits between obese group and severely obese group. The level of serum 25(OH)D3 was not declined while the level of serum ferritin was not elevated in Korean obese and severely obese women. This study has been performed with the limitation that the number of samples was not enough.

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