scholarly journals Global research trend in the treatment of the new Coronavirus diseases (COVID-19): bibliometric analysis

2020 ◽  
Author(s):  
Maxime Descartes Mbogning Fonkou ◽  
Abdourahamane Yacouba
Keyword(s):  
Randomized Clinical Trials ◽  
Treatment Options ◽  
The United States ◽  
Progressive Increase ◽  
Medical Problem ◽  
Research Trend ◽  
Publication Type ◽  
Medical Virology ◽  
New Treatment ◽  
Number Of Publications

AbstractThe Coronavirus 2019 (COVID-19) pandemic has caused worldwide concern and has become a major medical problem. Vaccines and therapeutics are important interventions for the management of this outbreak. This study aims to used bibliometric methods to identify research trends in the domain of therapeutics and vaccines to cure patients with COVID-19 since the beginning of the pandemic.The Web of Science Core Collection database was retrieved for articles on therapeutic approaches to coronavirus disease management published between January 1, 2020 and May 20, 2020. Identified and analyzed the data included title, corresponding author, language, publication time, publication type, research focus.A total of 1569 articles on coronavirus therapeutic means from 84 countries were published in 620 journals. We note the remarkable progressive increase in the number of publications related to research on therapies and vaccines for COVID-19. The United States provided the largest number of articles (405), followed by China (364). Journal of Medical Virology published most of them (n = 40). 1005 (64.05%) were articles, 286 (18.23%) were letters, 230 (14.66%) were reviews. The terms “COVID- 19” or “SARS-CoV-2” or “Coronavirus” or “hydroxychloroquine” or “chloroquine” or “2019-nCOV” or “ACE2” or “treatment” or “remdesivir” or “pneumonia” were most frequently used, as shown in the density visualization map. A network analysis based on keyword co-occurrence revealed five distinct types of studies: clinical, biological, epidemiological, pandemic management, and therapeutics (vaccines and treatments).COVID-19 is a major disease that has had an impact on international public health at the global level. Several avenues for treatment and vaccines have been explored. Most of them focus on older drugs used to treat other diseases that have been effective for other types of coronaviruses. There is a discrepancy in the results obtained from the studies of the drugs included in this study. Randomized clinical trials are needed to evaluate older drugs and develop new treatment options.

Global research trend in the treatment of the new Coronavirus diseases (COVID-19) : bibliometric analysis. (Preprint)

2020 ◽  
Author(s):  
Maxime Descartes Mbogning Fonkou ◽  
Abdourahamane YACOUBA
Keyword(s):  
Randomized Clinical Trials ◽  
Treatment Options ◽  
The United States ◽  
Progressive Increase ◽  
Medical Problem ◽  
Research Trend ◽  
Publication Type ◽  
Medical Virology ◽  
New Treatment ◽  
Number Of Publications

BACKGROUND The Coronavirus 2019 (COVID-19) pandemic has caused worldwide concern and has become a major medical problem. Vaccines and therapeutics are important interventions for the management of this outbreak. OBJECTIVE This study aims to used bibliometric methods to identify research trends in the domain of therapeutics and vaccines to cure patients with COVID-19 since the beginning of the pandemic. METHODS The Web of Science Core Collection database was retrieved for articles on therapeutic approaches to coronavirus disease management published between January 1, 2020 and May 20, 2020. Identified and analyzed the data included title, corresponding author, language, publication time, publication type, research focus. RESULTS A total of 1569 articles on coronavirus therapeutic means from 84 countries were published in 620 journals. We note the remarkable progressive increase in the number of publications related to research on therapies and vaccines for COVID-19. The United States provided the largest number of articles (405), followed by China (364). Journal of Medical Virology published most of them (n=40). 1005 (64.05%) were articles, 286 (18.23%) were letters, 230 (14.66%) were reviews. The terms "COVID- 19" or "SARS-CoV-2" or "Coronavirus" or "hydroxychloroquine" or "chloroquine" or "2019-nCOV" or "ACE2" or "treatment" or "remdesivir" or "pneumonia" were most frequently used, as shown in the density visualization map. A network analysis based on keyword co-occurrence revealed five distinct types of studies: clinical, biological, epidemiological, pandemic management, and therapeutics (vaccines and treatments). CONCLUSIONS COVID-19 is a major disease that has had an impact on international public health at the global level. Several avenues for treatment and vaccines have been explored. Most of them focus on older drugs used to treat other diseases that have been effective for other types of coronaviruses. There is a discrepancy in the results obtained from the studies of the drugs included in this study. Randomized clinical trials are needed to evaluate older drugs and develop new treatment options.

scholarly journals MAPPING THE FIELD: A BIBLIOMETRIC ANALYSIS OF EMPLOYEE VOICE

2021 ◽  
Vol 4 (13) ◽  
pp. 01-21
Author(s):  
Jen Ling Gan ◽  
Aqilah Yaacob
Keyword(s):  
Bibliometric Analysis ◽  
The United States ◽  
Employee Voice ◽  
Research Trend ◽  
Voice Behavior ◽  
Vos Viewer ◽  
The Future ◽  
Author Keywords ◽  
Number Of Publications ◽  
Global Research

Objective: There is limited literature that discussed the trend of ‘employee voice’. Hence, this bibliometric analysis is aimed to evaluate the global research growth to retrieve and analyze the publication on ‘employee voice’. The bibliometric analysis is used to search the database of Scopus from the oldest publication in 1986 to the recent publication in 2019. The objectives were to evaluate the trend of ‘employee voice’ research, details of co-authorship, leading institutions and countries, top scholars, and leading author keywords. Methodology: This study used VOS Viewer 1.6.11 to analyze and visualize the global research trend on ‘employee voice’ in analyzing the bibliographic data. Bibliometric maps were retrieved from VOS Viewer 1.6.11. Results: This study retrieved 443 journal articles from the Scopus database from 1986 to 2019. The publication’s trend revealed that the number of publications has been increasing steadily since 2005. The leading countries in ‘employee voice’ research are the United Kingdom and the United States. Among the fifteen leading universities, five of them were from the world’s top 150 universities. Among the keywords, ‘voice behavior’ has the most linkage with ‘employee voice’, which indicated that employee voice is active in the business and management field compared to other fields such as nursing and psychology. According to the author keywords analysis, ‘promotive voice’ and ‘prohibitive voice’ were found to become a potential concerned area in the future as they started to receive attention in 2017. Implication: This paper can be beneficial for academicians, organizations, and business policymakers in understanding the global trend of ‘employee voice’ besides discovering the future directions and opportunities for future studies.

scholarly journals The State of Lupus Clinical Trials: Minority Participation Needed

2019 ◽  
Vol 8 (8) ◽  
pp. 1245
Author(s):  
Saira Z. Sheikh ◽  
Nicole I. Wanty ◽  
Joncel Stephens ◽  
Kristen D. Holtz ◽  
Sheryl McCalla
Keyword(s):  
Clinical Trials ◽  
African Americans ◽  
Symptom Severity ◽  
Quality Care ◽  
Treatment Options ◽  
The United States ◽  
Minority Populations ◽  
Healthcare Staff ◽  
Minority Participation ◽  
New Treatment

In the United States, the reported prevalence of lupus is 100,000 to 500,000 patients. Lupus disproportionately affects minority populations, including African Americans and Latinos, and the associated health disparities are substantial. Women are at a higher risk of lupus than men and lupus prevalence is the highest in African Americans and Latinos compared to non-Hispanic whites. African Americans and Latinos also have increased disease symptom severity, experience more lupus-related complications, and have a two- to three-fold mortality rate compared to non-Hispanic Whites. Lupus clinical trials offer opportunities for quality care and can result in new treatment options, but African Americans and Latinos are underrepresented in clinical trials because of substantial patient- and provider-side barriers. In conjunction with the limited knowledge of clinical trials that potential participants may have, the healthcare staff approaching participants have limited time to adequately educate and explain the aspects of clinical trials. Indeed, ninety percent of clinical trials fail to meet their recruitment goals on time, so a multi-faceted approach is necessary to address the issue of low minority participation in clinical trials.

scholarly journals 1167. Trends in Multi-Drug-Resistant Gonorrhea, Gonococcal Isolate Surveillance Project, United States, 1987–2016

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S352-S352
Author(s):  
Sancta St. Cyr ◽  
Ellen Kersh ◽  
Hillard Weinstock ◽  
Elizabeth Torrone
Keyword(s):  
United States ◽  
Antimicrobial Susceptibility ◽  
Treatment Options ◽  
The United States ◽  
Drug Resistant ◽  
Appropriate Treatment ◽  
High Prevalence ◽  
Agar Dilution ◽  
Male Patients ◽  
New Treatment

Abstract Background Neisseria gonorrhoeae’s ability to develop resistance to antibiotics used for treatment and a limited development of new therapies have made this organism one of three urgent threat pathogens in the United States. We provide the first report of US trends in multi-drug-resistant (MDR) and extensively-drug-resistant (XDR) gonorrhea. Methods The Gonococcal Isolate Surveillance Project (GISP) monitors trends in antimicrobial susceptibility in N. gonorrhoeae in the United States. Antimicrobial susceptibility testing by agar dilution is performed on urethral isolates from male patients at participating STD clinics. Minimum inhibitory concentration (MIC) are used to identify isolates with resistance or reduced susceptibility using the following criteria: fluoroquinolones (ciprofloxacin [MIC ≥1.0 μg/mL]) and elevated MICs to cephalosporins (cefixime [MIC ≥0.25 μg/mL], ceftriaxone [MIC ≥0.25 μg/mL]) and macrolides (azithromycin [MIC ≥1.0 μg/mL before 2005 and ≥2.0 μg/mL 2005–2016]). In this analysis, MDR is defined as resistance or elevated MICs to ≥2 classes of antimicrobials; XDR as resistance or elevated MICs to ≥3 classes. This classification excludes penicillin and tetracycline due to their long history and high prevalence of gonococcal resistance. Results During 1987–2016, 159,445 isolates were collected through GISP. In 1998, the first MDR strains were identified. Although only 0.04% of isolates that year, these isolates showed elevated MICs to both cephalosporins and macrolides. By 2010, 1.0% of GISP isolates were MDR with elevated MICs or resistance to two of the cephalosporins, macrolides, or fluoroquinolones. In 2011, the proportion of isolates that were MDR peaked at 1.3%. In 2016, after minor fluctuations, 1.1% of GISP isolates were considered MDR. Only one occurrence of XDR, in 2011, has been seen in GISP. The strain was resistant to fluoroquinolones with elevated MICs to both cephalosporins and macrolides. Conclusion MDR and XDR gonorrhea have remained low over the past three decades; however, dual treatment with cephalosporins and macrolides is the last remaining recommended therapy for N. gonorrhoeae. Until new treatment options become available, a combination of surveillance and ensuring appropriate treatment are needed to delay further resistance. Disclosures All authors: No reported disclosures.

scholarly journals Surveillance and Treatment of Non-Muscle-Invasive Bladder Cancer in the USA

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Daniel A. Barocas ◽  
Denise R. Globe ◽  
Danielle C. Colayco ◽  
Ahunna Onyenwenyi ◽  
Amanda S. Bruno ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Treatment Options ◽  
Unmet Need ◽  
Patient Characteristics ◽  
The United States ◽  
Invasive Bladder Cancer ◽  
Muscle Invasive Bladder Cancer ◽  
The Usa ◽  
New Treatment ◽  
Muscle Invasive

Seventy percent of newly diagnosed bladder cancers are classified as non-muscle-invasive bladder cancer (NMIBC) and are often associated with high rates of recurrence that require lifelong surveillance. Currently available treatment options for NMIBC are associated with toxicities that limit their use, and actual practice patterns vary depending upon physician and patient characteristics. In addition, bladder cancer has a high economic and humanistic burden in the United States (US) population and has been cited as one of the most costly cancers to treat. An unmet need exists for new treatment options associated with fewer complications, better patient compliance, and decreased healthcare costs. Increased prevention of recurrence through greater adherence to evidence-based guidelines and the development of novel therapies could therefore result in substantial savings to the healthcare system.

virtual reality and augmented reality Applications in surgery：Analysis of the Scientific Literature (Preprint)

2021 ◽  
Author(s):  
Jin Lu ◽  
Yongqiang Xiao ◽  
Ye Zhou ◽  
Xiangdong Qi
Keyword(s):  
United States ◽  
Virtual Reality ◽  
Augmented Reality ◽  
Web Of Science ◽  
Scientific Literature ◽  
The United States ◽  
Research Trend ◽  
Related Field ◽  
H Index ◽  
Number Of Publications

BACKGROUND Background: Virtual reality (VR) and augmented reality (AR) have recently become popular research themes. However, there are no published bibliometric reports that have analyzed the corresponding scientific literature in relation to the application of these technologies in surgery. Our study aims to study the research trend on virtual reality and surgery, and compare the contribution of publications from different countries, institutions, journals and authors. OBJECTIVE We used a bibliometric approach to identify and analyze the scientific literature on virtual reality and surgery during 2001-2020 form Web of Science. GraphPad Prism 6, and VOSviewer software were used to collect and analyze the publication trend in related field, revealing the popular research topics, key authors, scientific institutions, countries, and journals. METHODS The Web of Science electronic database was searched to identify relevant papers on VR research in surgery. Basic publication and citation data were acquired using the “Analyze” and “Create Citation Report” functions of the database. Complete bibliographic data were exported to VOSviewer for further analyses. Visualization maps were generated to illustrate the recurring keywords and words mentioned in the titles and abstracts. RESULTS We identified a total of 3323 publications with citation frequency of 81919 times up to August 21, 2021. The United States accounted for the largest number of publications (30.575%), 31199 of total citations as well as the highest H-index (88). The sum of publications from China ranked the fifth, while the overall citations (3257) and H-index (29) ranked the eighth and the ninth, respectively. The paper published on Annals of Surgery in 2002 had been cited for 1759times, which was the most cited papers in related field. The “system research” seemed to be the hotspot in relevant scope. CONCLUSIONS The United States made the most outstanding contribution within this important field. There is a mismatch between the quantity and quality of publications from China. Latest progress can be tracked in Annals of Surgery. Augmented reality related researches may be hotspots in the near future.

scholarly journals Switching thrombopoietin receptor agonist treatments in patients with primary immune thrombocytopenia

2019 ◽  
Vol 10 ◽  
pp. 204062071983790 ◽  
Author(s):  
José R. González-Porras ◽  
Bertrand Godeau ◽  
Monica Carpenedo
Keyword(s):  
Immune Thrombocytopenia ◽  
Treatment Options ◽  
The United States ◽  
Term Treatment ◽  
Cross Resistance ◽  
Thrombopoietin Receptor ◽  
Long Term Treatment ◽  
Pharmacokinetic Properties ◽  
Primary Immune Thrombocytopenia ◽  
New Treatment

Primary immune thrombocytopenia (ITP) is a bleeding disorder that conventionally has been treated with steroids or other immunosuppressive treatments. The introduction of thrombopoietin receptor agonists (TPO-RAs), which increase platelet production, dramatically changed the treatment landscape for ITP by providing patients with well-tolerated, long-term treatment options. Two TPO-RAs, eltrombopag and romiplostim, have been approved in the United States and European Union for the treatment of ITP. Some patients do not benefit from the first TPO-RA they receive, so it is assumed that the alternate TPO-RA would have the same outcome. However, eltrombopag and romiplostim have distinct pharmacodynamic and pharmacokinetic properties and may have different tolerability and efficacy in individual patients with ITP. Published retrospective studies showed that >75% of patients who switched to the alternate TPO-RA maintained or achieved a response with the new treatment. Notably, most patients who switched due to lack of efficacy with the first TPO-RA responded to the alternate TPO-RA, which demonstrates an absence of cross-resistance between the two drugs. Therefore, switching to the alternate TPO-RA if the first TPO-RA fails to demonstrate a response should be considered before the use of a less-preferable option.

Global research production in glyphosate intoxication from 1978 to 2015: A bibliometric analysis

2016 ◽  
Vol 36 (10) ◽  
pp. 997-1006 ◽  
Author(s):  
SH Zyoud ◽  
WS Waring ◽  
SW Al-Jabi ◽  
WM Sweileh
Keyword(s):  
United States ◽  
The United States ◽  
Publication Type ◽  
Policy Makers ◽  
Document Type ◽  
H Index ◽  
Agricultural Industry ◽  
Research Production ◽  
Scopus Database ◽  
Number Of Publications

Background: Glyphosate (N-phosphonomethylglycine) has been used as a broad-spectrum herbicide that has been widely used in the agricultural industry and also available for home use. The main aim of this study is to present a general overview of glyphosate intoxication-related publications from its introducing since the early 1970s using bibliometric technique. Methods: On June 23, 2016, a literature search of the Scopus database was performed. We then extracted and analyzed the data using well-established qualitative and quantitative bibliometric indices: Publication year, affiliation, document type, country name, subject category, journal name, publishing language, and collaboration and citation patterns. Results: We recognized a total of 3735 publications on glyphosate published between 1973 and 2015. There were 875 publications related to glyphosate intoxication in the Scopus database published between 1978 and 2015. Articles (757) comprised 86.5% of the total publications, followed by reviews (41; 4.7%). Most publications were published in English (87.9%), followed by Portuguese (6.6%). The number of publications related to glyphosate intoxication increased from 44 in 1978–1987 up to 152 in 1996–2005 and then quadrupled in 2006–2015. The United States was the leading country with 180 documents representing 20.6%, followed by Brazil (120; 13.7%), Canada (78; 8.9%), Argentina (61; 7.0%), and France (57; 6.5%). The 85.6% of the publications was cited, and the average of citation per document was 17.13 with h-index of 55. Furthermore, the United States achieved the highest h-index of 33. Most of the global international collaborations are made with researchers from the United States, who collaborated with 23 countries/territories in 44 publications. Conclusions: The trends in global glyphosate-related research between 1978 and 2015 were evaluated by a bibliometric technique. Results showed that English was the leading publishing language, and the major publication type was original article. Findings showed that number of research publications related to glyphosate intoxication increased significantly in the last decade. The United States and Brazil are the two most productive countries in research on glyphosate intoxication. This study will be beneficial to policy makers by identifying areas that need greater investment and research funding to target appropriate agriculture sectors so as to improve glyphosate safety in a global setting.

scholarly journals A Global Research Trend on Organizational Citizenship Behaviour: A Bibliometric Analysis

2020 ◽  
Vol 2 (1) ◽  
pp. 55-71
Author(s):  
Jen Ling Gan ◽  
Halimah Mohd Yusof
Keyword(s):  
Bibliometric Analysis ◽  
Organizational Citizenship ◽  
The United States ◽  
Research Trend ◽  
Vos Viewer ◽  
Global Trend ◽  
Bibliographic Data ◽  
Author Keywords ◽  
Number Of Publications ◽  
Global Research

There are limited literatures that discussed on the trend of OCB. Hence, this bibliometric analysis is aimed to evaluate the global research growth to retrieve and analyse the publication on OCB. The bibliometric analysis is used to search the database of Scopus from the oldest publication in 1988 to the recent publication in 2019. The objectives were to evaluate the output of publications, co-authorship, leading countries and institutions, top authors, and co-occurrences of author keywords. This study used VOS Viewer 1.6.11 to analyse and visualise the global research trend on OCB in analysing the bibliographic data. Bibliometric maps were retrieved from VOS Viewer 1.6.11. This study retrieved 2, 356 journal articles from Scopus database from 1988 to 2019. The publication’s trend revealed that the number of publications has been increasing steadily since 2002. The leading countries in OCB research are the United States and China. Among the fifteen leading universities, five of them were from the world’s top 150 universities. Among the keywords, ‘commitment’ has the most link with OCB, which indicated that OCB is active in the management field compared to other fields such as nursing and psychology. This paper can be beneficial for academicians, organisations, and business policymakers in understanding the global trend of OCB besides discovering the future directions and opportunities for future studies.  

scholarly journals Visualizing the intellectual structure and recent research trends of diabetic retinopathy

2021 ◽  
Vol 14 (8) ◽  
pp. 1248-1259
Author(s):  
Li Xiao ◽  
◽  
Qi Liu ◽  
Jun Peng ◽  
Jun-Feng Yan ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
The United States ◽  
Research Trends ◽  
Intellectual Structure ◽  
Research Trend ◽  
Distribution Analysis ◽  
China National Knowledge Infrastructure ◽  
The Core ◽  
The Difference ◽  
Number Of Publications

AIM: To analyze the intellectual structure and recent research trends in diabetic retinopathy (DR) and unearth potential knowledge. METHODS: English DR publication included in this study was exported from the Web of Science Core Collection, and Chinese DR publication was exported from China National Knowledge Infrastructure from the establishment time of the database to 2019. CiteSpace and Microsoft Excel were used to visually analyze DR research, including analysis of the number of publications, highly cited publication analysis, spatial distribution analysis, and keyword co-occurrence analysis. RESULTS: A total of 23 795 English studies and 11 577 Chinese studies, including 2089 studies related to traditional Chinese medicine (TCM), were obtained. The data suggested the following: 1) The number of English and Chinese DR publications increased over time, and the growth rate of English publications was relatively fast. 2) The distribution of international scholars and institutions was close, while the distribution was scattered in China. Shanghai Jiao Tong University has the largest number of publications. Tien-Yin Wong was the core author with the largest number of publications. England and the United States are the core of international DR research cooperation. 3) Optical coherence tomography and risk factors are recent international research hot spots and trends. The difference is that TCM is a recent research trend under DR in China. CONCLUSION: DR has drawn an increasing amount of attention worldwide. The focus of research in this field has shifted from tertiary type DR treatment to secondary prevention strategies which focus on the screening and monitoring of disease progression. The advantages of TCM in the prevention of DR have attracted attention, and it is worth incorporating this with Western medicine to address this challenge.

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