scholarly journals Engaging the complexity of diet and healthy aging in humans

2021 ◽  
Author(s):  
Alistair M Senior ◽  
Véronique Legault ◽  
Francis B Lavoie ◽  
Nancy Presse ◽  
Pierrette Gaudreau ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin E ◽  
Nutrient Intake ◽  
Aging Process ◽  
Healthy Aging ◽  
Normal Variation ◽  
Blood Biomarkers ◽  
Future Studies ◽  
Nutritional Geometry ◽  
Analytical Approaches

Little is known about how normal variation in dietary patterns in humans affects the aging process, largely because both nutrition and the physiology of aging are highly complex and multidimensional. Here, we apply the nutritional geometry framework to data from 1560 older adults followed over four years to assess how nutrient intake patterns affect the aging process. Aging was quantified via blood biomarkers integrated to measure loss of homeostasis. Additionally, we extend nutritional geometry to 19 micronutrients. Salient results include benefits of intermediate protein and vitamin E intake. Broadly, we show that there are few simple answers of "good" or "bad" nutrients – optimal levels are generally intermediate, but dependent on other nutrients. Simpler linear/univariate analytical approaches are insufficient to capture such associations. We present an interactive tool to explore the results, and our approach presents a roadmap for future studies to explore the full complexity of the nutrition-aging landscape.

scholarly journals Can physical activity influence the effect of the COVID-19 vaccine on older adults?

2020 ◽  
Vol 22 ◽  
Author(s):  
Francisco José Gondim Pitanga ◽  
Cristiano Penas Seara Pitanga ◽  
Carmem Cristina Beck
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Immune Response ◽  
Aging Process ◽  
Elderly Population ◽  
The Elderly ◽  
Influenza Vaccines ◽  
Future Studies ◽  
Response Capacity ◽  
Opinion Article

Abstract Studies have shown reductions in the immune response capacity with the aging process (immunosenescence). Lifestyle factors (physical activity and diet) have been investigated as possible adjuvants to improve the effect of vaccines on the immune system in the elderly. The aim of this opinion article is to analyze studies on physical activity and the effect of influenza vaccines in an attempt to suggest that their results can also be found in future studies on physical activity and vaccines against COVID-19. Considering the results of the studies analyzed, it could be suggested that the practice of physical activity improves responses to the influenza vaccine. Thus, it could be assumed that, when transferring these findings to COVID-19, the importance of regular physical activity in the specific elderly population becomes extremely relevant during the COVID-19 pandemic.

Trends in Dietary Intake of Vitamins A, C, and E in German Children and Adolescents – Results of the DONALD Study

2003 ◽  
Vol 73 (5) ◽  
pp. 335-342 ◽  
Author(s):  
Alexy ◽  
Kersting ◽  
Sichert-Hellert
Keyword(s):  
Vitamin E ◽  
Nutrition Education ◽  
Time Trends ◽  
Nutrient Intake ◽  
Age Groups ◽  
Food Groups ◽  
Fortified Food ◽  
Vitamin Intake ◽  
Dietary Records ◽  
The Impact

Intake of vitamins A, C, and E was evaluated and age and time trends were assessed on the basis of 3-day weighed dietary records (n = 5121) of 2- to 18-year old boys (n = 417) and girls (n = 425) enrolled in the DONALD Study (Dortmund Nutritional and Anthropometric Longitudinally Designed Study) 1986–2001. Intake of vitamin A remains stable over time, intake of vitamin C increases linearly, and intake of vitamin E follows a nonlinear trend. Age trends of vitamins A and C (per MJ) were nonlinear with a minimum at the beginning adolescence, while intake of vitamin E (per MJ) increased linearly. Girls had higher nutrient densities but lower intakes expressed as percent of reference values. Fortified food in total had a higher impact on time trends of nutrient intake than other single food groups defined here. Our results point to the impact of the food industry on long-term nutrient intake, but also underline the necessity of nutrition education even in young age groups to improve vitamin intake.

Analysis of Self-Concept in Older Adults in Different Contexts

2004 ◽  
Vol 20 (4) ◽  
pp. 262-274 ◽  
Author(s):  
Manuel de Gracia Blanco ◽  
Josep Garre Olmo ◽  
María Marcó Arbonès ◽  
Pilar Monreal Bosch
Keyword(s):  
Older Adults ◽  
Nursing Home ◽  
Depressive Symptoms ◽  
External Validity ◽  
Aging Process ◽  
Well Being ◽  
Self Esteem ◽  
Self Concept ◽  
Self Perceptions ◽  
Discriminatory Capacity

Summary: Self-concept is a construct consisting of a group of specific self-perceptions that are hierarchically organized. Age-associated changes of self-concept are related to the individual's perception of the changes occurring throughout the aging process. The authors examined external validity and internal consistency of an instrument that has been developed to assess self-concept in older adults and examined self-concept's characteristics in two different contexts. Results confirm the multidimensionality of the scale and show a satisfactory external validity, indicating good discriminatory capacity. Findings support the hypothesis that older people who live in a nursing home have a poor self-esteem, self-concept, and psychological well-being and have a greater presence of depressive symptoms than people who live in their own home.

scholarly journals Comprehensive modeling of bloodstain aging by multivariate Raman spectral resolution with kinetics

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Ayari Takamura ◽  
Daisuke Watanabe ◽  
Rintaro Shimada ◽  
Takeaki Ozawa
Keyword(s):  
Spectral Resolution ◽  
Aging Process ◽  
Near Infrared ◽  
Biochemical Characterization ◽  
Forensic Analysis ◽  
Chemical Mechanism ◽  
Experimental Conditions ◽  
Spectral Components ◽  
Different Temperatures ◽  
Analytical Approaches

Abstract Blood, as a cardinal biological system, is a challenging target for biochemical characterization because of sample complexity and a lack of analytical approaches. To reveal and evaluate aging process of blood compositions is an unexplored issue in forensic analysis, which is useful to elucidate the details of a crime. Here we demonstrate a spectral deconvolution model of near-infrared Raman spectra of bloodstain to comprehensively describe the aging process based on the chemical mechanism, particularly the kinetics. The bloodstain spectra monitored over several months at different temperatures are decomposed into significant spectral components by multivariate calculation. The kinetic schemes of the spectral components are explored and subsequently incorporated into the developed algorithm for the optimal spectral resolution. Consequently, the index of bloodstain aging is proposed, which can be used under different experimental conditions. This work provides a novel perspective on the chemical mechanisms in bloodstain aging and facilitates forensic applications.

scholarly journals Multidirectional Overground Robotic Training Leads to Improvements in Balance in Older Adults

Robotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 101
Author(s):  
Lara A. Thompson ◽  
Mehdi Badache ◽  
Joao Augusto Renno Brusamolin ◽  
Marzieh Savadkoohi ◽  
Jelani Guise ◽  
...  
Keyword(s):  
Older Adults ◽  
Healthy Aging ◽  
Robotic System ◽  
Control Group ◽  
Support Surface ◽  
Training Methods ◽  
Robotic Training ◽  
Balance Confidence ◽  
Balance Ability ◽  
Abc Scale

For the rapidly growing aging demographic worldwide, robotic training methods could be impactful towards improving balance critical for everyday life. Here, we investigated the hypothesis that non-bodyweight supportive (nBWS) overground robotic balance training would lead to improvements in balance performance and balance confidence in older adults. Sixteen healthy older participants (69.7 ± 6.7 years old) were trained while donning a harness from a distinctive NaviGAITor robotic system. A control group of 11 healthy participants (68.7 ± 5.0 years old) underwent the same training but without the robotic system. Training included 6 weeks of standing and walking tasks while modifying: (1) sensory information (i.e., with and without vision (eyes-open/closed), with more and fewer support surface cues (hard or foam surfaces)) and (2) base-of-support (wide, tandem and single-leg standing exercises). Prior to and post-training, balance ability and balance confidence were assessed via the balance error scoring system (BESS) and the Activities specific Balance Confidence (ABC) scale, respectively. Encouragingly, results showed that balance ability improved (i.e., BESS errors significantly decreased), particularly in the nBWS group, across nearly all test conditions. This result serves as an indication that robotic training has an impact on improving balance for healthy aging individuals.

scholarly journals Breeder Diet Strategies for Generating Ttpa-Null and Wild-Type Mice with Low Vitamin E Status to Assess Neurological Outcomes

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Katherine M Ranard ◽  
Matthew J Kuchan ◽  
John W Erdman
Keyword(s):  
Animal Model ◽  
Vitamin E ◽  
Mouse Model ◽  
Wild Type ◽  
Future Studies ◽  
Neurological Outcomes ◽  
Transfer Protein ◽  
And Function ◽  
The Brain ◽  
Vitamin E Status

ABSTRACT Studying vitamin E [α-tocopherol (α-T)] metabolism and function in the brain and other tissues requires an animal model with low α-T status, such as the transgenic α-T transfer protein (Ttpa)–null (Ttpa−/−) mouse model. Ttpa+/− dams can be used to produce Ttpa−/− and Ttpa+/+mice for these studies. However, the α-T content in Ttpa+/− dams’ diet requires optimization; diets must provide sufficient α-T for reproduction, while minimizing the transfer of α-T to the offspring destined for future studies that require low baseline α-T status. The goal of this work was to assess the effectiveness and feasibility of 2 breeding diet strategies on reproduction outcomes and offspring brain α-T concentrations. These findings will help standardize the breeding methodology used to generate the Ttpa−/− mice for neurological studies.

Participatory development of the food literacy intervention “GUSTO” for older adults in Germany

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
F Zastrow ◽  
K Neher ◽  
H Hassel
Keyword(s):  
Older Adults ◽  
Focus Group ◽  
Focus Groups ◽  
Everyday Life ◽  
Healthy Aging ◽  
Participatory Approach ◽  
Target Group ◽  
Focus Group Discussions ◽  
Group Discussions ◽  
Food Literacy

Abstract Background Healthy aging is one of the major challenges currently faced by an aging population. Food literacy (FL) refers to the ability to apply knowledge and practical skills regarding healthy and sustainable nutrition into everyday life. The project “GUSTO” is sponsored by the Bavarian State Ministry of Health and Care and aims to contribute to enjoyable aging by developing the nutritional skills of people aged 65 and over. This community-based program comprises independent working groups of older adults guided by peer moderators. The FL intervention is developed in cooperation with the target group. Methods The nutritional situation of older adults was first established through a literature research. The results of this research were compared to the “self-perceived food literacy scale” by Poelman et al. (2018) and the “nutritional framework for literacy courses” by Johannsen et al. (2019). The resulting data provided a basis for focus group discussions carried out in six municipalities, supported by local practice partners. In six guided focus group discussions, a number of recurring themes were identified and summarized. Results The focus groups consisted of a total of 44 people between 62 and 88 years of age (average age: 73.1 ± 6.1 years). 22.7 % were men. The group discussions revealed resources used and barriers encountered in terms of FL and interests of older adults. It was evident that, due to the high density of information available, the participants found it difficult to identify reliable information and to implement it in their everyday life. At the request of the focus groups, topics such as the best before date and the use of food waste were added to the intervention. Conclusions Older adults find it challenging to identify reliable nutritional information and implement it in their everyday life. With the help of the participatory approach outlined in this study, target group-related issues can be identified and taken into account in the intervention. Key messages Older adults can be involved in the development of an FL intervention. A participatory approach allows target group-related issues and specific needs to be taken into account in the intervention.

scholarly journals A Qualitative Study toward Technologies for Active and Healthy Aging: A Thematic Analysis of Perspectives among Primary, Secondary, and Tertiary End Users

2021 ◽  
Vol 18 (14) ◽  
pp. 7489
Author(s):  
Margherita Rampioni ◽  
Adrian Alexandru Moșoi ◽  
Lorena Rossi ◽  
Sorin-Aurel Moraru ◽  
Dan Rosenberg ◽  
...  
Keyword(s):  
Older Adults ◽  
Qualitative Study ◽  
Information And Communication Technologies ◽  
Healthy Aging ◽  
Perceived Usefulness ◽  
Research Network ◽  
Political Agenda ◽  
User Centered Design ◽  
Sensing Technology ◽  
Care Systems

It is expected that, by 2050, people aged over 60 in 65 nations will constitute 30% of the total population. Healthy aging is at the top of the world political agenda as a possible means for hindering the collapse of care systems. How can ICT/sensing technology meet older people’s needs for active and healthy aging? This qualitative study carried out in Italy and Romania in 2020 involved 30 participants: older adults, caregivers, and stakeholders. Based on a user-centered design approach, this study aimed to understand which requirements of ICT/sensing technologies could match people’s needs of active and healthy aging. Findings highlighted that ICT/sensing technology needs to focus on six major themes: (1) learnability, (2) security, (3) independence, empowerment, and coaching values, (4) social isolation, (5) impact of habit, culture, and education variables, and (6) personalized solutions. These themes are consistent with the Active Aging framework and the factors that influence perceived usefulness and potential benefits among older adults. Consequently, this study shows how well-known, but still unresolved, issues affect the field of information and communication technologies (ICTs) to promote active and healthy aging. This suggests that the reinforcement of the public health system, especially considering the pandemic effect, requires a concrete and formidable effort from an interdisciplinary research network.

Psychometric evaluation of the healthy aging instrument in older adults

2021 ◽  
pp. 1-12
Author(s):  
Hilal Yildirim ◽  
Kevser Isik ◽  
Sıdıka Özlem Cengizhan
Keyword(s):  
Older Adults ◽  
Healthy Aging ◽  
Psychometric Evaluation

scholarly journals Visualization approaches to support healthy aging: A systematic review

2016 ◽  
Vol 23 (3) ◽  
pp. 600 ◽  
Author(s):  
Uba Backonja ◽  
Nai-Ching Chi ◽  
Yong Choi ◽  
Amanda K Hall ◽  
Thai Le ◽  
...  
Keyword(s):  
Older Adults ◽  
Health Behaviors ◽  
Healthy Aging ◽  
A Priori ◽  
Aging In Place ◽  
Future Research ◽  
Health Technologies ◽  
Data Visualizations ◽  
Informatics Tools

Background: Health technologies have the potential to support the growing number of older adults who are aging in place. Many tools include visualizations (data visualizations, visualizations of physical representations). However, the role of visualizations in supporting aging in place remains largely unexplored.Objective: To synthesize and identify gaps in the literature evaluating visualizations (data visualizations and visualizations of physical representations), for informatics tools to support healthy aging.Methods: We conducted a search in CINAHL, Embase, Engineering Village, PsycINFO, PubMed, and Web of Science using a priori defined terms for publications in English describing community-based studies evaluating visualizations used by adults aged ≥65 years.Results: Six out of the identified 251 publications were eligible. Most studies were user studies and varied methodological quality. Three visualizations of virtual representations supported performing at-home exercises. Participants found visual representations either (a) helpful, motivational, and supported their understanding of their health behaviors or (b) not an improvement over alternatives. Three data visualizations supported understanding of one’s health. Participants were able to interpret data visualizations that used precise data and encodings that were more concrete better than those that did not provide precision or were abstract. Participants found data visualizations helpful in understanding their overall health and granular data.Conclusions: Studies we identified used visualizations to promote engagement in exercises or understandings of one’s health. Future research could overcome methodological limitations of studies we identified to develop visualizations that older adults could use with ease and accuracy to support their health behaviors and decision-making.

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