ANTIDERMATOPHYTIC ACTIVITY OF GARLIC (ALLIUM SATIVUM) IN VITRO

1995 ◽  
Vol 34 (4) ◽  
pp. 278-279 ◽  
Author(s):  
PANKAJALAKSHMI V. VENUGOPAL ◽  
TARALAKSHMI V. VENUGOPAL
2017 ◽  
Vol 9 (2) ◽  
pp. 71
Author(s):  
Nurhasanah Nurhasanah ◽  
Fauzia Andrini ◽  
Yulis Hamidy

Shallot (Allium ascalonicum L.) has been known as traditional medicine. Shallot which has same genus with garlic(Allium sativum L.) contains allicin that is also found in garlic and has been suspected has fungicidal activity toCandida albicans. It is supported by several researches. Therefore, shallot is suspected has antifungal activity too.The aim of this research was to know antifungal activity of shallot’s water extortion againsts Candida albicans invitro. This was a laboratory experimental research which used completely randomized design, with diffusion method.Shallot’s water extortion was devided into three concentrations, there were 50%, 100% and 200%. Ketoconazole 2%was positive control and aquadest was negative control. The result of this research based on analysis of varians(Anova), there was significant difference between several treatments and was confirmed with Duncan New MultipleRange Test (DNMRT) p<0,05, there was significant difference between 100% shallot’s water extortion with othertreatments, but there was no significant difference between 50% shallot’s water extortion with 200% shallot’s. Theconclusion was shallot’s water extortion had antifungal activity againsts Candida albicans with the best concentration100%, but it was lower than ketoconazole 2%.


2021 ◽  
Vol 5 (3) ◽  
pp. 138
Author(s):  
AdiDharma Widjaya ◽  
MeinyFaudah Amin ◽  
Aryadi ◽  
BoediOetomo Roeslan

2012 ◽  
Vol 7 (43) ◽  
pp. 5792-5795 ◽  
Author(s):  
I Metwally E ◽  
E El Denary M ◽  
M K Omar A ◽  
Naidoo Y ◽  
H Dewir Y

Author(s):  
Shahid Khan ◽  
Neeta Raj Sharma

Objective: In vitro analysis of Allium sativum and Allium ampeloprasum was performed to evaluate their antifungal potential against Alternaria triticina (ITCC 5496), causative agent of leaf blight in wheat and Magnaporthe oryzae (ITCC 6808), causative agent of blast disease in rice.Methods: Ethanol extracts of A. ampeloprasum and A. sativum were prepared by crushing their bulb in liquid nitrogen and then immersing them in 90% ethanol and 100% ethanol separately. The antifungal activity test was determined by quantitative assay using 96-well microtiter plate and results were statistically analyzed using GraphPad Prism v. 5.03.Results: A. triticina and M. oryzae showed above 90% and 95% growth inhibition, respectively against the ethanol extracts of A. ampeloprasum. Conversely, growth inhibition of either fungus remained mostly below 35% against ethanol extracts of A. sativum at all tested concentrations.Conclusion: Ethanol extracts of A. ampeloprasum have relatively higher antifungal potential than ethanol extracts of A. sativum and could be considered as a natural alternative to chemical fungicides.Keywords: Allium sativum, Allium ampeloprasum, Alternaria triticina, Magnaporthe oryzae.


Kultivasi ◽  
2016 ◽  
Vol 15 (3) ◽  
Author(s):  
Y. Sholihin ◽  
Erni Suminar ◽  
Wieny Heriliya Rizky ◽  
G. G. Pitaloka
Keyword(s):  

Bawang putih merupakan komoditas penting di Indonesia. Indonesia merupakan negara terbesar pengimpor bawang putih. Permasalahan yang dihadapi dalam teknik produksi benih secara konvensional menjadi salah satu faktor pembatas tidak optimalnya pengembangan dan penyebaran benih tersebut. Produksi benih  in vitro dapat dijadikan sebagai metode alternatif dalam perbanyakan benih sumber kultivar unggul. Penelitian ini bertujuanuntuk mendapatkan komposisi kinetin dan GA3 terbaik pada media dasar MS untuk regenerasi eksplan meristemsecara in vitro.Penelitian dilaksanakan di Laboratorium Kultur JaringanBalai Pengembangan Benih Hortikultura dan Aneka Tanaman Pasir Banteng, Kecamatan Jatinangor, Kabupaten Sumedang, Provinsi Jawa Barat, yang berlangsung dari bulan April hingga Juli 2015. Eksplan yang digunakan adalah meristem bawang putih kultivar Tawangmangu. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 12 perlakuan dan 3 ulangan. Media yang digunakan adalah Murashige dan Skoog (MS) dengan penambahan zat pengatur tumbuh Kinetin (0,0 mg L-1; 1,5 mg L-1; 3,0 mg L-1; 4,5 mg L-1) dan GA3 (0,0 mg L-1; 0,5 mg L-1; 1,0 mg L-1).Perlakuan komposisi Kinetin dan GA3 pada media MS memberikan pengaruh nyata terhadap pertumbuhan bawang putih kultivar Tawangmangu in vitro, dan perlakuan yang terbaik diperoleh pada perlakuan 4,5 mg L-1 Kin + 1,0 mg L-1 GA3 untuk peubah jumlah daun, tetapi perlakuan media tanpa kinetinmemberikan pengaruh yang lebih baik terhadap tinggi tunas, jumlah akar, dan panjang akar pada pertumbuhan eksplan meristem bawang putih Kultivar Tawangmangu in vitro.Kata Kunci:Bawang Putih Kultivar Tawangmangu, Eksplan Meristem, GA3, In Vitro, Kinetin, Media MS


2019 ◽  
Vol 57 (3B) ◽  
pp. 9 ◽  
Author(s):  
Tien Cuong Nguyen ◽  
Thi Anh Phuong Chu ◽  
Hai Van Nguyen

ABSTRACT-QMFS2019Poultry production provides source of protein and contributes an important income for Vietnamese farmers. Among the poultry in Vietnam, ducks account for 27.3% of head of poultry and even 55.7% in Mekong Delta region. Along with the development of rearing ducks, bacterial, viral and fungal diseases occurring in the two last decades induced bad effect for poultry producer. Escherichia coli, Salmonella enterica, Streptococcal or Pasteurella act as major pathogenic bacteria in duck. The aims of this study were to investigate the antibacterial activity of garlic Allium sativum against E. coli, Staphylococcus aureus, Salmonella Typhimurium and to evaluate the effect of garlic on growth performance of duck from 1-28 old-days. The results indicated that fresh garlic and dried garlic powder showed inhibitory effect against pathogenic tested strains from 2% and 4% w/v, respectively. The inhibition zones and the minimal inhibitory concentration (MIC) values of garlic extract ranged from 11.3-28.3 mm and 0.02-0.2 g/ml, respectively. After 28 days of diet with garlic supplemented, D3 (2% of fresh garlic in water) showed significantly different in weight gain (WG), feed conversion ratio (FCR), protein efficiency ratio (PER), average daily weight (ADW); whereas, D2 (2% of garlic powder in basal diet) only possessed a difference significant in feed consumption (FC) compared to the D1 (control without garlic supplementation). The obtained results demonstrated the potential of garlic application in poultry production.


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11934
Author(s):  
Jiashun Chen ◽  
Fang Wang ◽  
Yexin Yin ◽  
Xiaokang Ma

Garlic (Allium sativum) is an essential vegetable that has been widely utilized as seasoning, flavoring, culinary and in herbal remedies. Garlic contains several characteristic organosulfur compounds, such as diallyl sulfide, allicin (diallyl thiosulphate), γ-glutamylcysteine, and S-allyl cysteine (alliin) and ajoene, which garlic has beneficial effects on inflammation, oxidative stress markers, hypertension, hyperlipidaemia and endothelial function in vitro or in animal model. These bioactive molecules are also playing pivotal role in livestock and fisheries production apart from its application in humans. Supplementation of animal feed with garlic and its related products is consistent with the modern agricultural concept of organic animal husbandry. This review compiles the information describing the effects of feeding garlic and its extracts on selected performance parameters in animals (chicken, rabbits, ruminants, pigs and fish). This review may provide reference for scientists and entrepreneurs to investigate the applications of feeds added with garlic and allicin by-products for the improvement of animal husbandry and aquatic production.


2021 ◽  
Vol 1 (1) ◽  
pp. 41-52
Author(s):  
Chioma E. Irozuru Irozuru ◽  
Janet O. Olugbodi ◽  
Uche Okuu Arunsi ◽  
Olusola Ladeji

Background: Allium cepa, Allium sativum, and Monodora myristica are commonly sourced food condiments in every household in Nigeria. In the present study, we investigated the phytochemical compositions, in vitro and in vivo antioxidant activity of these plants. Methods: The aqueous extracts from the A. cepa, A. sativum, and M. myristica were evaluated for phytochemical composition using standard protocols while the antioxidant activities were evaluated using the reducing power assay. Forty-five (45) Male Wistar rats (weighing 185±10 g) were divided into five groups (n=9) and were orally administered with 100 mg/kg BW each of A. sativum, M. myristica, A. cepa, and ascorbic acid while the control group received 0.5 mL/kg BW distilled water alone. Animals (n=3) from each group were sacrificed after the 20th, 25th, and 30th days of oral administration. The blood and tissue samples were collected for the analysis of biochemical parameters. Result: Our results revealed the presence of flavonoids, alkaloids, tannins, saponins, and terpenes in the plant extracts. A. sativum had the highest reducing power capacity followed by M. myristica and then A. cepa. The in vitro antioxidants activities demonstrated by the plant extracts were higher than that of ascorbic acid but less than butylated hydroxytoluene. In vivo antioxidant studies showed a marked increase (p<0.05) in the level of catalase with a concurrent decrease (p<0.05) in the levels of MDA and H2O2 in the liver and kidney of rats administered with aqueous extracts of the condiments compared to the normal control and ascorbic acid in the following order control < ascorbic acid < A. cepa < M. myristica < A. sativum. Conclusion: Based on these findings, we infer that the aqueous extracts of A. cepa, A. sativum, and M. myristica are rich in antioxidants and as a result could serve as promising novel functional foods and nutraceuticals


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