scholarly journals Exposure to Chinese famine in early life and the risk of sensory impairment in adulthood

2020 ◽  
pp. jech-2020-213775
Author(s):  
Hongguo Rong ◽  
Xiaozhen Lai ◽  
Elham Mahmoudi ◽  
Hai Fang
Keyword(s):  
Early Life ◽  
Late Childhood ◽  
Sensory Impairment ◽  
Fetal Period ◽  
Unexposed Group ◽  
Multi Stage ◽  
Sensory Impairments ◽  
Negative Effect ◽  
Famine Exposure ◽  
The Relationship

BackgroundStudies have shown that malnutrition in early life has a negative effect on midlife cognitive functions. Little is known, however, about the relationship between early-life malnutrition and visual, hearing or dual sensory impairments in adulthood. This study aims to investigate the association between exposure to the 1959–1961 Chinese famine in early life and sensory impairments in adulthood.MethodsA total of 6347 adults born between 1952 and 1964 surveyed in the 2015 China Health and Retirement Longitudinal Study were included in this study. The presence of sensory impairments was identified by self-reported assessment of visual and hearing functions. The associations between multi-stage early-life famine exposure and sensory functions were estimated using the multiple generalised linear model.ResultsCompared with the unexposed group, respondents exposed to famine in the fetal period and late childhood had a significantly higher risk of hearing impairment (OR 1.54, 95% CI 1.06 to 2.24; OR 1.75, 95% CI 1.23 to 2.50) and dual sensory impairments (OR 1.45, 95% CI 1.00 to 2.11; OR 1.55, 95% CI 1.09 to 2.21), respectively. Furthermore, in severely famine-affected areas, the early, mid and late childhood-exposed groups were more likely to have hearing and dual sensory impairments than the unexposed group. Those associations were not observed in less famine-affected areas. However, no significant association was found between famine exposure and visual impairment in early-life famine-exposed group.ConclusionExposure to Chinese famine in the fetal period and late childhood was linked to hearing and dual sensory impairments in adulthood.

The relationship between famine exposure during early life and ascending aorta dilatation in adults

2021 ◽  
pp. 1-29
Author(s):  
Yu-qing Huang ◽  
Lin Liu ◽  
Kenneth Lo ◽  
Yu-ling Yu ◽  
Chao-lei Chen ◽  
...  
Keyword(s):  
Early Life ◽  
Chinese Population ◽  
Ascending Aorta ◽  
Late Childhood ◽  
Cardiac Ultrasound ◽  
Multivariate Logistic Regression ◽  
Fetal Period ◽  
Famine Exposure ◽  
Aorta Dilatation ◽  
The Relationship

Abstract Background and aims: The relationship between exposure to famine in early life and the risk of ascending aorta dilatation (AAD) in adulthood is still unclear, therefore we aimed to examine the association in a Chinese population. Methods and results: We investigated the data of 2,598 adults that were born between 1,952 and 1,964 in Guangdong, China. All enrolled subjects were categorized into five groups: not exposed to famine, exposed during fetal period, and exposed during early, mid or late childhood. AAD was assessed by cardiac ultrasound. Multivariate logistic regression and interaction tests were performed to estimate the odds ratio (OR) and confidence interval (CI) on the association between famine exposure and AAD. There were 2,598 (943 male, mean age 58.3 ± 3.68 years) participants were enrolled, and 270 (10.4%) subjects with AAD. We found that famine exposure (OR=2.266, 95% CI: 1.477, 3.477, P=0.013) associated with elevated AAD after adjusting for multiple confounders. In addition, compared with the non-exposure group, the adjusted ORs for famine exposure during fetal period, early, mid or late childhood were 1.374 (95% CI: 0.794, 2.364, P=0.251), 1.976 (95% CI: 1.243, 3.181, P=0.004), 1.929 (95% CI: 1.237, 3.058, P=0.004) and 2.227 (95% CI: 1.433, 3.524, P<0.001), respectively. Subgroup analysis showed that the effect of famine exposure on the association with AAD was more pronounced in female, current smokers, people with BMI ≥24 kg/m2 and hypertensive patients. Conclusion: We observed that exposure to famine during early life was linked to AAD in adulthood.

scholarly journals The relationship between famine exposure in early life and ascending aorta dilatation in adulthood

2020 ◽  
Author(s):  
Yu-qing HUANG ◽  
Lin LIU ◽  
Kenneth Lo ◽  
Yu-ling YU ◽  
Chao-lei CHEN ◽  
...  
Keyword(s):  
Early Life ◽  
Ascending Aorta ◽  
Exposed Group ◽  
Late Childhood ◽  
Cardiac Ultrasound ◽  
Multivariate Logistic Regression ◽  
Famine Exposure ◽  
Aorta Dilatation ◽  
Stratified Analysis ◽  
The Relationship

Abstract BackgroundThe relationship between malnutrition and ascending aorta dilatation (AAD) is still unclear. Therefore, the aim of this study was to examine the association of exposure to the Chinese famine during early life with AAD in adulthood.MethodsWe investigated data of 2598 adults born between 1952 and 1964 from Guangdong, China. All enrolled subjects were divided into five groups: no exposed, fetal exposed, early, mid and late childhood exposed. AAD was assessed by cardiac ultrasound. Multivariate logistic regression and interaction tests were used to estimate the odds ratio (OR) and confidence interval (CI) between famine exposure and AAD.ResultsThere were 2598 (943 male, mean age 59.1 ± 3.65 years) participants were enrolled, among them consist of 270 (10.4%) subjects with AAD. Compared with no exposed group, the adjusted ORs for AAD widening from fetal-exposed, early, mid to late childhood exposed were 1.374 (95% CI: 0.794, 2.364, P = 0.251), 1.976 (95% CI: 1.243, 3.181, P = 0.004), 1.929 (95% CI: 1.237, 3.058, P = 0.004) and 2.227 (95% CI: 1.433, 3.524, P < 0.001), respectively. Stratified analysis showed that the effect of famine exposure on AAD was more pronounced in female, smokers, BMI ≥ 24 kg/m2 and hypertensive patients.ConclusionsWe observed that exposure to famine during early life was an independent risk factor for AAD in adulthood; this effect was not modified by gender, BMI, smoking, hypertension and diabetes.Yu-qing HUANG and Lin LIU are equally to this paper.

scholarly journals Famine Exposure During Early Life Increased the Risk of Ascending Aorta Dilatation in Adults

2020 ◽  
Author(s):  
Yu-qing HUANG ◽  
Lin LIU ◽  
Kenneth Lo ◽  
Yu-ling YU ◽  
Chao-lei CHEN ◽  
...  
Keyword(s):  
Risk Factor ◽  
Early Life ◽  
Independent Risk Factor ◽  
Ascending Aorta ◽  
Late Childhood ◽  
Multivariate Logistic Regression ◽  
Famine Exposure ◽  
Aorta Dilatation ◽  
Stratified Analysis ◽  
The Relationship

Abstract Background: The relationship between malnutrition and ascending aorta dilatation (AAD) is still unclear. Therefore, the aim of this study was to examine the association of exposure to the Chinese famine during early life with AAD in adulthood. Methods: We investigated data of 2598 adults born between 1952 and 1964 from Guangdong, China. All enrolled subjects were divided into five groups: no exposed, fetal exposed, early, mid and late childhood exposed. AAD was assessed by cardiac ultrasound. Multivariate logistic regression and interaction tests were used to estimate the odds ratio (OR) and confidence interval (CI) between famine exposure and AAD. Results: There were 2598 (943 male, mean age 59.1 ± 3.65 years) participants were enrolled, among them consist of 270 (10.4%) subjects with AAD. We found that famine exposure (OR=2.266, 95% CI: 1.477, 3.477, P=0.013), age, smoking, hypertension, elevated SBP, elevated BMI was an independent risk factor for AAD. In addition, compared with no exposed group, the adjusted ORs for AAD widening from fetal-exposed, early, mid to late childhood exposed were 1.374 (95% CI: 0.794, 2.364, P=0.251), 1.976 (95% CI: 1.243, 3.181, P=0.004), 1.929 (95% CI: 1.237, 3.058, P=0.004) and 2.227 (95% CI: 1.433, 3.524, P<0.001), respectively. Stratified analysis showed that the effect of famine exposure on AAD was more pronounced in female, smokers, BMI ≥24 kg/m2 and hypertensive patients. Conclusions: We observed that exposure to famine during early life was an independent risk factor for AAD in adulthood; this effect was not modified by gender, BMI, smoking, hypertension and diabetes.

scholarly journals Early-Life Exposure to the Chinese Great Famine and Later Cardiovascular Diseases

2021 ◽  
Vol 66 ◽  
Author(s):  
Zhenghe Wang ◽  
Yanhui Dong ◽  
Rongbin Xu ◽  
Xijie Wang ◽  
Yanhui Li ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Early Life ◽  
Matched Control ◽  
Longitudinal Survey ◽  
Control Group ◽  
Unexposed Group ◽  
Great Famine ◽  
Early Life Exposure ◽  
Exposed Infant ◽  
Famine Exposure

Objectives: This study aimed to examine the association between early life famine exposure and adulthood cardiovascular diseases (CVDs) risk.Methods: A total of 5,504 subjects were selected using their birthdate from national baseline data of the China Health and Retirement Longitudinal Survey to analyze the association between famine exposure in early life and CVDs risk in adulthood. CVDs was defined based on the self-reported doctor’s diagnosis.Results: The prevalence of CVDs in the unexposed group, fetal-exposed, infant-exposed, and preschool-exposed groups was 15.0%, 18.0%, 21.0%, and 18.3%, respectively. Compared with the unexposed group, fetal-exposed, infant-exposed and preschool-exposed groups had higher CVDs risk in adulthood (p &lt; 0.05). Compared with the age-matched control group, infancy exposed to famine had a significantly higher adulthood CVDs risk (OR = 1.52, 95% CI: 1.15, 2.01; p = 0.006). The association seems to be stronger among population with higher education level (Pinteraction = 0.043). Sensitivity analysis revealed consistent association between early-life famine exposure and adult CVDs risk.Conclusion: Early life exposed to the China great famine may elevate the risk of CVDs in adulthood.

scholarly journals Early-Life Exposure to the Chinese Famine and Risk of Cognitive Decline

2019 ◽  
Vol 8 (4) ◽  
pp. 484 ◽  
Author(s):  
Hongguo Rong ◽  
Xiaozhen Lai ◽  
Elham Mahmoudi ◽  
Hai Fang
Keyword(s):  
Cognitive Decline ◽  
Cognitive Performance ◽  
Early Life ◽  
Late Life ◽  
Cognitive Status ◽  
Word Recall ◽  
Long Term Effects ◽  
Negative Effects ◽  
Multi Stage ◽  
Famine Exposure

Previous studies on the Chinese famine suggested long-term effects of early-life famine exposure on health conditions. This study aims to investigate the association between exposure to the Chinese famine of 1959–1961 at different early-life stages and the risk of cognitive decline in adulthood. A total of 6417 adults born between 1952 and 1964 in the 2015 survey data of China Health and Retirement Longitudinal Study were included in this study. Cognitive performance was estimated through a series of comprehensive neuropsychological tests, including the Telephone Interview of Cognitive Status (TICS-10), word recall, and pentagon drawing. Multiple generalized linear model (GLM) was employed to detect the association between multi-stage early-life famine exposure and late-life cognitive performance. Compared with the unexposed group, respondents exposed to famine in the fetal period performed worse in the TICS (difference −0.52, 95% confidence interval (CI): −0.93 to −0.10), word recall (difference −0.46, 95% CI: −0.74 to −0.19), and general cognition (difference −1.05, 95% CI: −1.64 to −0.47). Furthermore, we also found negative effects of famine exposure on performance of word recall and pentagon drawing in the early (word recall difference −0.56, 95% CI: −1.00 to −0.11; pentagon drawing difference −0.76, 95% CI: −1.40 to −0.12), mid (word recall difference −0.46, 95% CI: −0.81 to −0.11; pentagon drawing difference −0.66, 95% CI: −1.16 to −0.16), and late (word recall difference −0.30, 95% CI: −0.55 to −0.04; pentagon drawing difference −0.75, 95% CI: −1.13 to −0.37) childhood-exposed groups. Early-life famine exposure in different stages is positively associated with late-life cognitive decline. Fetal famine exposure might affect the overall cognitive status in adulthood, and childhood famine exposure has potential adverse effects on visuospatial episodic memory.

scholarly journals Exposure to Famine During Early Life and Abdominal Obesity in Adulthood: Findings from the Great Chinese Famine During 1959–1961

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 903 ◽  
Author(s):  
Dan Liu ◽  
Dong-mei Yu ◽  
Li-yun Zhao ◽  
Hong-yun Fang ◽  
Jian Zhang ◽  
...  
Keyword(s):  
Abdominal Obesity ◽  
Urban Areas ◽  
Early Life ◽  
Healthy Lifestyle ◽  
Positive Association ◽  
Fetal Life ◽  
Cross Sectional ◽  
Famine Exposure ◽  
Nationally Representative ◽  
The Relationship

Undernutrition during early life may lead to obesity in adulthood. This study was conducted to examine the relationship between famine exposure during early life and the risk of abdominal obesity in adulthood. A total of 18,984 and 16,594 adults were surveyed in 2002 and 2010–2012 in two nationally representative cross-sectional surveys, namely China Nutrition and Health Survey, respectively. The risk of abdominal obesity was evaluated for participants born during 1956–1961 and compared with that of participants born during 1962–1964. The overall prevalence of abdominal obesity in adulthood showed a positive association with famine exposure during early life. The odds ratios of famine exposure were 1.31 (1.19–1.44) and 1.28 (1.17–1.40) in 2002 during fetal life and infancy and 1.09 (1.00–1.19) in 2012 during fetal life, respectively. The relationships between famine exposure and abdominal obesity across the famine exposure groups were distinct among females and those who lived in urban areas and were physical inactive (p < 0.05). Exposure to famine during early life was associated with increased risks of abdominal obesity in adulthood, which was partially alleviated by healthy lifestyle factors (e.g., physical activity).

Association of Exposure to Chinese Famine in Early Life with the Risk of Metabolic Syndrome in Adulthood

2020 ◽  
Vol 76 (2) ◽  
pp. 140-146 ◽  
Author(s):  
Yue Peng ◽  
Miaomiao Hai ◽  
Pengcheng Li ◽  
Yongjie Chen
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Early Childhood ◽  
Early Life ◽  
Lower Risk ◽  
Late Childhood ◽  
Fetal Life ◽  
Childhood Exposure ◽  
Study Results ◽  
Famine Exposure

Objective: To explore the association of famine exposure in early life with the risk of metabolic syndrome (MS) in the ­Chinese adults. Methods: Data were obtained from the wave 2009 of the China Health and Nutrition Survey. MS was identified when 3 or more of the following components happened: (1) waist circumference >90 cm in males or >85 cm in females; (2) fasting glucose ≥6.1 mmol/L; (3) systolic blood pressure ≥130 mm Hg/diabolic blood pressure ≥85 mm Hg; (4) fasting triglyceride ≥1.70 mmol/L; and (5) high-density lipids cholesterol <1.04 mmol/L. All participants were divided into 5 groups: no exposure, born after 1961; fetal life exposure, between 1959 and 1961; early childhood exposure, between 1956 and 1958; mid-childhood exposure, between 1953 and 1955; and late childhood exposure, between 1949 and 1952. A total of 2,080 subjects were included in this study. Results: In rural, famine exposure in fetal life and early childhood was associated with the lower risk of MS (p = 0.0491 and 0.0245; OR 0.583 and 0.703; and OR, 95% CI 0.341–0.998 and 0.517–0.956, respectively). But famine exposure in late childhood was associated with the higher risk of MS (p = 0.0140; OR 3.096; and OR, 95% CI 1.257–7.625). Famine exposure in early childhood was associated with the lower risk of MS (p = 0.0120; OR 0.633; and OR, 95% CI 0.443–0.904) in males. Conclusions: Famine exposure in mid- and late-childhood was associated with the higher risk of MS, especially in rural, males, and severe famine areas.

Self-Reported Sensory Impairments in Older Adults and their Association with Self-Rated Health and Mortality Outcomes

2021 ◽  
pp. 089826432110591
Author(s):  
Bernard A. Steinman ◽  
Jennifer Tabler ◽  
Casandra M. Mittlieder ◽  
Bremen Whitlock ◽  
Carrie E. Goodman
Keyword(s):  
Older Adults ◽  
Daily Living ◽  
Sensory Impairment ◽  
Medicare Beneficiaries ◽  
Self Rated Health ◽  
Sensory Impairments ◽  
Logistic Regressions ◽  
Nationally Representative ◽  
The Relationship ◽  
Health And Mortality

Objectives This study assessed the relationship between self-reported impairments of vision, hearing, and dual sensory impairment, and change in self-rated health/mortality status over a 5-year period. Methods Data came from the National Health and Aging Trends Study, a nationally representative survey of Medicare beneficiaries ages 65 and older. Analyses consisted of a series of ordinal logistic regressions stratified by sex. Results For both women and men, self-reported sensory impairments were not statistical predictors of self-rated health/mortality, when other dimensions of health, such as physical functioning, participation, and activities of daily living functioning were included in models. Discussion Understanding how self-reported sensory impairments impact self-rated health could assist in targeting rehabilitation strategies to older adults who experience sensory impairments.

scholarly journals The relationship between famine exposure during early life and body mass index in adulthood: A systematic review and meta-analysis

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192212 ◽  
Author(s):  
Jielin Zhou ◽  
Liangjian Zhang ◽  
Peng Xuan ◽  
Yong Fan ◽  
Linsheng Yang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Body Mass ◽  
Early Life ◽  
Meta Analysis ◽  
Famine Exposure ◽  
The Relationship

Investigation the relationship between test anxiety and emotional intelligence (EQ) in boys and girls of high schools of tehran city

2011 ◽  
Vol 26 (S2) ◽  
pp. 283-283
Author(s):  
M. Farahati ◽  
A. Mahdavian ◽  
S. Agahi
Keyword(s):  
Emotional Intelligence ◽  
High Schools ◽  
Test Anxiety ◽  
Cluster Sampling ◽  
Reverse Correlation ◽  
Multi Stage ◽  
Emotional Quotient Inventory ◽  
Negative Effect ◽  
The Relationship ◽  
Difficult Situations

IntroductionThe aim of this study is to investigation the relationship between test anxiety and emotional intelligence (EQ) in boys and girls of high schools of Tehran city.MethodsIn this study 100 boys and 100 girls were selected via multi stage cluster sampling from the mentioned high schools. The participants were asked to answer two questionnaires. The beck anxiety inventory and bar- on emotional quotient inventory were used to measure anxiety and emotional intelligence.ResultsThe result of this study suggested that test anxiety has a negative effect on EQ and therefore all EQ parameters have reverse correlation with amount of test anxiety. Such correlation was not seen between anxiety and phenomenon such as self expression, inter personal affairs and sympathy.ConclusionEmotional intelligence is defined as the awareness and ability to manage emotions in a healthy and productive manner, By providing a suitable educational environment in schools and families, we can help students learn how to control their emotions and thereby increase their EQ to be able to manage their emotions while encountering exams or other difficult situations in life.

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