scholarly journals Theoretical Prediction of Presupernova Neutrinos and Their Detection

2020 ◽  
Vol 70 (1) ◽  
pp. 121-145 ◽  
Author(s):  
C. Kato ◽  
K. Ishidoshiro ◽  
T. Yoshida
Keyword(s):  
Stellar Evolution ◽  
Massive Star ◽  
Current Status ◽  
Detection Techniques ◽  
The Core ◽  
Sn 1987A ◽  
Neutrino Detection ◽  
Points Of View ◽  
Remarkable Progress ◽  
Made In

More than 30 years have passed since the successful detection of supernova (SN) neutrinos from SN 1987A. In the last few decades, remarkable progress has been made in neutrino detection techniques, through which it may be possible to detect neutrinos from a new source, presupernova (pre-SN) neutrinos. They are emitted from a massive star prior to core bounce. Because neutrinos escape from the core freely, they carry information about the stellar physics directly. Pre-SN neutrinos may play an important role in verifying our understanding of stellar evolution for massive stars. Observation of pre-SN neutrinos, moreover, may serve as an alarm regarding an SN explosion a few days in advance if the progenitor is located in our vicinity, enabling us to observe the next galactic SN. In this review, we summarize the current status of pre-SN neutrino studies from both the theoretical and observational points of view.

scholarly journals Sexuality education in Europe – An assessment of the current state, challenges and good practice

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
L Brockschmidt ◽  
O Ivanova ◽  
E Ketting
Keyword(s):  
Teacher Training ◽  
Central Asia ◽  
Sexuality Education ◽  
Good Practice ◽  
Monitoring And Evaluation ◽  
Well Being ◽  
Legal Framework ◽  
Current Status ◽  
Remarkable Progress ◽  
Made In

Abstract Background Comprehensive sexuality education is a crucial factor for protecting the health and well-being of children and young people. A recent assessment, conducted by the Federal Centre for Health Education and the International Planned Parenthood Federation European Network (IPPF EN), gives an up-to-date overview of the current status of sexuality education (SE) in schools in 25 European and Central Asian countries. It further provides information on challenges and good practice in this field. Methods Pre-tested questionnaires were sent to representatives of governmental (Ministries of Health or Education) and nongovernmental organisations (IPPF member associations) in 25 countries in Europe and Central Asia. All representatives of the nongovernmental (25) and two-thirds of those in governmental organisations (16) responded. The questions were grouped under five themes related to SE: legal framework, status of implementation, barriers and opposition, youth-friendly sexual and reproductive health (SRH) services, and national data on adolescent SRH. Results In 15 of the 25 countries surveyed, a legal framework exists (law/ policy/ strategy) which supports SE in schools. In 11 countries, SE is mandatory in schools, and in 10 countries SE clearly has a comprehensive character. In most countries, SE is integrated into broader teaching subjects, e.g. biology or life skills education. A lack of teacher training and of monitoring and evaluation of SE programmes has been identified in the majority of countries. Conclusions In the past two decades, remarkable progress has been made in developing and implementing SE in the region. Nevertheless, further improvements are urgently needed, as differences between and within countries persist. These include the quality and the comprehensiveness of SE programmes, the monitoring and evaluation of these programmes and the development and implementation of teacher training. Key messages Remarkable progress has been made in implementing sexuality education in Europe and Central Asia. Nevertheless, further action is needed to reduce differences in implementation and quality between and within countries.

scholarly journals SUPERNOVA 1987A: CELEBRATING A SILVER JUBILEE

2013 ◽  
Vol 53 (A) ◽  
pp. 606-611
Author(s):  
Nino Panagia
Keyword(s):  
Neutron Star ◽  
Binary System ◽  
Massive Star ◽  
Core Collapse ◽  
Single Star ◽  
The Core ◽  
Sn 1987A ◽  
Supernova 1987A ◽  
Collapse Process

The story of the SN 1987A explosion is briefly reviewed. Although this supernova was somewhat peculiar, the study of SN 1987A has clarified quite a number of important aspects of the nature and the properties of supernovae, such as the confirmation of the core collapse of a massive star as the cause of the explosion, as well the confirmation that the decays 56Ni–56Co–56Fe at early times and 44Ti–44Sc at late times, are the main sources of the energy radiated by the ejecta. Still we have not been able to ascertain whether the progenitor was a single star or a binary system, nor have we been able to detect the stellar remnant, a neutron star that should be produced in the core collapse process.

Cosmic gamma-ray bursts from primordial stars: A new renaissance in astrophysics?

2015 ◽  
Vol 30 (28n29) ◽  
pp. 1545021
Author(s):  
Pascal Chardonnet ◽  
Anastasia Filina ◽  
Valery Chechetkin ◽  
Mikhail Popov ◽  
Andrey Baranov
Keyword(s):  
Nuclear Matter ◽  
Observational Data ◽  
Stellar Evolution ◽  
Physical Interpretation ◽  
Hot Spots ◽  
Massive Star ◽  
Gamma Ray ◽  
Gamma Ray Bursts ◽  
New Paradigm ◽  
The Core

The cosmic gamma-ray bursts are certainly an enigma in astrophysics. The “standard fireball” scenario developed during many years has provided a possible explanation of this phenomena. The aim of this work is simply to explore a new possible interpretation by developing a coherent scenario inside the global picture of stellar evolution. At the basis of our scenario, is the fact that maybe we have not fully understood how the core of a pair instability supernova explodes. In such way, we have proposed a new paradigm assuming that the core of such massive star, instead of doing a symmetrical explosion, is completely fragmented in hot spots of burning nuclear matter. We have tested our scenario with observational data like GRB spectra, lightcurves, Amati relation and GRB-SN connection, and for each set of data we have proposed a possible physical interpretation. We have also suggested some possible test of this scenario by measurement at high redshifts. If this scenario is correct, it tells us simply that the cosmic gamma-ray bursts are a missing link in stellar evolution, related to an unusual explosion.

Will Love Tear Us Apart: Adapting the Lyrical to the Ludic

CounterText ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 217-235
Author(s):  
Gordon Calleja
Keyword(s):  
Design Process ◽  
Game Design ◽  
Digital Games ◽  
Design Decisions ◽  
The Core ◽  
Lyrical Poetry ◽  
Insight Into ◽  
Made In

This paper gives an insight into the design process of a game adaptation of Joy Division's Love Will Tear Us Apart (1980). It outlines the challenges faced in attempting to reconcile the diverging qualities of lyrical poetry and digital games. In so doing, the paper examines the design decisions made in every segment of the game with a particular focus on the tension between the core concerns of the lyrical work being adapted and established tenets of game design.

‘To wise for a woman’

2018 ◽  
Author(s):  
Nicola Clark
Keyword(s):  
Marital Problems ◽  
The Core ◽  
The Family ◽  
Made In ◽  
The Way

While there were clear strategic aims in the way that marriages were made in the Howard dynasty during this period, the family was only unusual in that it operated at the very top of the aristocratic hierarchy and was therefore able to use marital alliances to successfully recover and bolster both status and finances. Where they were different, however, was in the experience of some of these women within marriage. By and large, the marriages made by and for members of the family, including women, seem to have been as successful as others of their class. However, three women close to the core of the dynasty experienced severe marital problems, even ‘failed’ marriages, almost simultaneously during the 1520s and 1530s. The records generated by these episodes tell us about the way in which the family operated as a whole, and the agency of women in this context, and this chapter therefore reconstructs these disputes for this purpose.

scholarly journals Diagnosis and Therapeutic Management of Liver Fibrosis by microRNA

2021 ◽  
Vol 22 (15) ◽  
pp. 8139
Author(s):  
Tomoko Tadokoro ◽  
Asahiro Morishita ◽  
Tsutomu Masaki
Keyword(s):  
Liver Fibrosis ◽  
Viral Infections ◽  
Primary Biliary Cholangitis ◽  
Medical Need ◽  
Key Factor ◽  
Complications Of Cirrhosis ◽  
And Control ◽  
Functional Rnas ◽  
Remarkable Progress ◽  
Made In

Remarkable progress has been made in the treatment and control of hepatitis B and C viral infections. However, fundamental treatments for diseases in which liver fibrosis is a key factor, such as cirrhosis, alcoholic/nonalcoholic steatohepatitis, autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis, are still under development and remain an unmet medical need. To solve this problem, it is essential to elucidate the pathogenesis of liver fibrosis in detail from a molecular and cellular perspective and to develop targeted therapeutic agents based on this information. Recently, microRNAs (miRNAs), functional RNAs of 22 nucleotides, have been shown to be involved in the pathogenesis of liver fibrosis. In addition, extracellular vesicles called “exosomes” have been attracting attention, and research is being conducted to establish noninvasive and extremely sensitive biomarkers using miRNAs in exosomes. In this review, we summarize miRNAs directly involved in liver fibrosis, miRNAs associated with diseases leading to liver fibrosis, and miRNAs related to complications of cirrhosis. We will also discuss the efficacy of each miRNA as a biomarker of liver fibrosis and pathology, and its potential application as a therapeutic agent.

scholarly journals Formation of GW190521 from stellar evolution: the impact of the hydrogen-rich envelope, dredge-up and 12C(α, γ)16O rate on the pair-instability black hole mass gap

2020 ◽  
Author(s):  
Guglielmo Costa ◽  
Alessandro Bressan ◽  
Michela Mapelli ◽  
Paola Marigo ◽  
Giuliano Iorio ◽  
...  
Keyword(s):  
Stellar Evolution ◽  
Reaction Rate ◽  
Primary Component ◽  
Mass Reduction ◽  
Black Hole Mass ◽  
Core Mass ◽  
The Core ◽  
Mass Gap ◽  
M Stars ◽  
The Impact

Abstract Pair-instability (PI) is expected to open a gap in the mass spectrum of black holes (BHs) between ≈40 − 65 M⊙ and ≈120 M⊙. The existence of the mass gap is currently being challenged by the detection of GW190521, with a primary component mass of $85^{+21}_{-14}$ M⊙. Here, we investigate the main uncertainties on the PI mass gap: the 12C(α, γ)16O reaction rate and the H-rich envelope collapse. With the standard 12C(α, γ)16O rate, the lower edge of the mass gap can be 70 M⊙ if we allow for the collapse of the residual H-rich envelope at metallicity Z ≤ 0.0003. Adopting the uncertainties given by the starlib database, for models computed with the 12C(α, γ)16O rate −1 σ, we find that the PI mass gap ranges between ≈80 M⊙ and ≈150 M⊙. Stars with MZAMS > 110 M⊙ may experience a deep dredge-up episode during the core helium-burning phase, that extracts matter from the core enriching the envelope. As a consequence of the He-core mass reduction, a star with MZAMS = 160 M⊙ may avoid the PI and produce a BH of 150 M⊙. In the −2 σ case, the PI mass gap ranges from 92 M⊙ to 110 M⊙. Finally, in models computed with 12C(α, γ)16O −3 σ, the mass gap is completely removed by the dredge-up effect. The onset of this dredge-up is particularly sensitive to the assumed model for convection and mixing. The combined effect of H-rich envelope collapse and low 12C(α, γ)16O rate can lead to the formation of BHs with masses consistent with the primary component of GW190521.

scholarly journals Contextualization of the Bioeconomy Concept through Its Links with Related Concepts and the Challenges Facing Humanity

2021 ◽  
Vol 13 (14) ◽  
pp. 7746
Author(s):  
Leire Barañano ◽  
Naroa Garbisu ◽  
Itziar Alkorta ◽  
Andrés Araujo ◽  
Carlos Garbisu
Keyword(s):  
Environmental Economics ◽  
Green Economy ◽  
Added Value ◽  
Economic Activities ◽  
Biological Resources ◽  
Beneficial Effects ◽  
The Core ◽  
Points Of View ◽  
Broad Interpretation ◽  
Shed Light

The concept of bioeconomy is a topic of debate, confusion, skepticism, and criticism. Paradoxically, this is not necessarily a negative thing as it is encouraging a fruitful exchange of information, ideas, knowledge, and values, with concomitant beneficial effects on the definition and evolution of the bioeconomy paradigm. At the core of the debate, three points of view coexist: (i) those who support a broad interpretation of the term bioeconomy, through the incorporation of all economic activities based on the production and conversion of renewable biological resources (and organic wastes) into products, including agriculture, livestock, fishing, forestry and similar economic activities that have accompanied humankind for millennia; (ii) those who embrace a much narrower interpretation, reserving the use of the term bioeconomy for new, innovative, and technologically-advanced economic initiatives that result in the generation of high-added-value products and services from the conversion of biological resources; and (iii) those who stand between these two viewpoints. Here, to shed light on this debate, a contextualization of the bioeconomy concept through its links with related concepts (biotechnology, bio-based economy, circular economy, green economy, ecological economics, environmental economics, etc.) and challenges facing humanity today is presented.

scholarly journals Implantable Thin Film Devices as Brain-Computer Interfaces: Recent Advances in Design and Fabrication Approaches

Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 204
Author(s):  
Yuhao Zhou ◽  
Bowen Ji ◽  
Minghao Wang ◽  
Kai Zhang ◽  
Shuaiqi Huangfu ◽  
...  
Keyword(s):  
Thin Film ◽  
High Resolution ◽  
Future Research ◽  
Nano Fabrication ◽  
Computer Interfaces ◽  
Continuous Progress ◽  
Open Mesh ◽  
Remarkable Progress ◽  
Thin Film Devices ◽  
Made In

Remarkable progress has been made in the high resolution, biocompatibility, durability and stretchability for the implantable brain-computer interface (BCI) in the last decades. Due to the inevitable damage of brain tissue caused by traditional rigid devices, the thin film devices are developing rapidly and attracting considerable attention, with continuous progress in flexible materials and non-silicon micro/nano fabrication methods. Therefore, it is necessary to systematically summarize the recent development of implantable thin film devices for acquiring brain information. This brief review subdivides the flexible thin film devices into the following four categories: planar, open-mesh, probe, and micro-wire layouts. In addition, an overview of the fabrication approaches is also presented. Traditional lithography and state-of-the-art processing methods are discussed for the key issue of high-resolution. Special substrates and interconnects are also highlighted with varied materials and fabrication routines. In conclusion, a discussion of the remaining obstacles and directions for future research is provided.

scholarly journals Developing an end-to-end simulation framework of supernova neutrino detection

2020 ◽  
Author(s):  
Masamitsu Mori ◽  
Yudai Suwa ◽  
Ken’ichiro Nakazato ◽  
Kohsuke Sumiyoshi ◽  
Masayuki Harada ◽  
...  
Keyword(s):  
Neutron Star ◽  
Neutrino Emission ◽  
Neutrino Detectors ◽  
Sn 1987A ◽  
Neutrino Detection ◽  
Time Simulation ◽  
Consistent Manner ◽  
Long Time ◽  
Neutron Star Cooling ◽  
Proto Neutron Star

Abstract Massive stars can explode as supernovae at the end of their life cycle, releasing neutrinos whose total energy reaches 1053erg. Moreover, neutrinos play key roles in supernovae, heating and reviving the shock wave as well as cooling the resulting proto-neutron star. Therefore, neutrino detectors are waiting to observe the next galactic supernova and several theoretical simulations of supernova neutrinos are underway. While these simulation concentrate mainly on only the first one second after the supernova bounce, the only observation of a supernova with neutrinos, SN 1987A, revealed that neutrino emission lasts for more than 10 seconds. For this reason, long-time simulation and analysis tools are needed to compare theories with the next observation. Our study is to develop an integrated supernova analysis framework to prepare an analysis pipeline for treating galactic supernovae observations in the near future. This framework deals with the core-collapse, bounce and proto-neutron star cooling processes, as well as with neutrino detection on earth in a consistent manner. We have developed a new long-time supernova simulation in one dimension that explodes successfully and computes the neutrino emission for up to 20 seconds. Using this model we estimate the resulting neutrino signal in the Super-Kamiokande detector to be about 1,800 events for an explosion at 10 kpc and discuss its implications in this paper. We compare this result with the SN 1987A observation to test its reliability.

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