Actions of Diethylstilbestrol in the Albino Rat

1957 ◽  
Vol 190 (2) ◽  
pp. 255-258 ◽  
Author(s):  
E. W. Hartsook ◽  
N. D. Magruder
Keyword(s):  
Body Weight ◽  
Feed Efficiency ◽  
Body Weight Gain ◽  
Albino Rats ◽  
Normal Male ◽  
Albino Rat ◽  
Feeding Technique ◽  
Testes Size ◽  
Ad Libitum ◽  
Ad Libitum Feeding

Four experiments were conducted utilizing either weanling or young adult normal male albino rats. These animals were fed either stock diets or semi-synthetic diets, containing either 0, 0.15, 0.3, 0.6 or 2.4 µg of diethylstilbestrol/gm, either by the trio or ad libitum feeding technique for periods of 6–15 weeks. It is concluded that diethylstilbestrol feeding in the albino rat induces statistically significant decreases in body weight gain, feed efficiency, body length, and testes size; it induces statistically significant increases in basal metabolic rate and in pituitary, thyroid and adrenal sizes.

EFFETS DES METHODES DE RATIONNEMENT SUR LES PERFORMANCES ET LA QUALITE DES CARCASSES DES PORCS DE MARCHE

1976 ◽  
Vol 56 (2) ◽  
pp. 347-353 ◽  
Author(s):  
PAUL FLIPOT ◽  
G. L. ROY
Keyword(s):  
Body Weight ◽  
Feed Efficiency ◽  
Feed Restriction ◽  
Restricted Diet ◽  
Mineral Supplementation ◽  
Ad Libitum ◽  
Vitamin And Mineral Supplementation ◽  
Ad Libitum Feeding ◽  
Crossbred Pigs ◽  
Feeding Systems

Growth, feed efficiency, and carcass data were obtained on ninety-four (94) crossbred pigs, to study the effect of types of feed restriction. The feeding treatments used in this experiment were as follows: (1) ad libitum; (2) 30–45 min per meal twice a day; (3) restricted to 85% of treatment 1, but with a 15% increase in protein, vitamin, and mineral supplementation; the pigs were started on this treatment at 27 kg of body weight; (4) same as treatment 3, but starting at 57 kg of body weight; (5) fasting once a week, starting at 27 kg of body weight; (6) same as treatment 5, but starting at 57 kg of body weight. During the rest of the week, pigs on treatments 5 and 6 were fed as on treatment 2. The pigs fed ad libitum were superior (P = 0.05) in growth rate and feed efficiency to those on a restricted diet. Those which fasted once a week starting at a body weight of 27 kg were significantly inferior (P = 0.05) to those on the other treatments. Backfat thickness and loin length were increased (P = 0.05) by the ad libitum feeding treatment, whereas carcass length and weight, ham weight, and rib eye area were not significantly affected (P = 0.05) by the feeding systems. Castrated males were superior (P = 0.05) to females in growth and inferior (P = 0.05) in carcass quality. The females had longer carcasses, leaner hams, and larger rib eye areas (P = 0.05) than the males. Crossbred Poland China × Yorkshire–Lacombe (P × Y–Lc) had heavier and fatter carcasses (P = 0.05) than crossbred Poland China × Yorkshire–Landrace (P × Y–Ld). However, rib eye area and dressing percentage were superior (P = 0.05) for the P × Y–Lc cross.

scholarly journals Metabolic programming effects initiated in the suckling period predisposing for adult-onset obesity cannot be reversed by calorie restriction

2013 ◽  
Vol 304 (5) ◽  
pp. E486-E494 ◽  
Author(s):  
Malathi Srinivasan ◽  
Saleh Mahmood ◽  
Mulchand S. Patel
Keyword(s):  
Body Weight ◽  
Calorie Restriction ◽  
Leptin Receptor ◽  
Body Weight Gain ◽  
Male Rats ◽  
Cytokine Signaling ◽  
Milk Formula ◽  
Adult Onset ◽  
Ad Libitum ◽  
Ad Libitum Feeding

Neonatal rats reared on high-carbohydrate (HC) milk formula developed chronic hyperinsulinemia and adult-onset obesity due to programming of islets and the hypothalamic energy circuitry. In this study, calorie restriction by pair-feeding was imposed on HC male rats (HC/PF) to normalize food intake similar to that of mother-fed (MF) rats from weaning until postnatal day 140. A group of HC/PF rats was switched over to ad libitum feeding (HC/PF/AL) from days 90 to 140. Pair-feeding reduced body weight gains and serum insulin and leptin levels in HC/PF rats compared with HC rats, but these parameters were restored to HC levels in the HC/PF/AL rats after ad libitum feeding. Interestingly, the heightened insulin secretory response of isolated islets from adult HC/PF and HC/PF/ AL rats to glucose, acetylcholine, and oxymetazoline were not significantly different from the responses of islets from HC rats. Similarly, the expression of neuropeptide Y and proopiomelanocortin in the hypothalamus was not significantly different among HC, HC/PF, and HC/PF/AL rats. Expression of the leptin receptor in the hypothalami from the HC, HC/PF, and HC/PF/AL rats mirrored that of serum leptin, whereas suppressor of cytokine signaling 3 ( Socs3) expression remained high in these three groups. The results indicate that, although calorie restriction resulted in reduction in body weight gain and normalized the serum hormonal pattern, the programed predisposition for the hypersecretory capacity of islets and the hypothalamic hyperphagic response in the HC rats could not be permanently overcome by the pair-feeding imposed on HC rats.

Influence of Origin or Controlled Feeding On Longevity of Sprague-Dawley Rats

1998 ◽  
Vol 17 (2_suppl) ◽  
pp. 57-78 ◽  
Author(s):  
E.V. Knight ◽  
D.S. Barrett ◽  
C.M. Keenan ◽  
J.P. Kimball ◽  
B.H. Eitzen ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Food Consumption ◽  
Crude Protein ◽  
Body Weight Gain ◽  
Sprague Dawley ◽  
The Third ◽  
Sd Rats ◽  
Ad Libitum ◽  
Ad Libitum Feeding

Two-year studies were undertaken in Sprague-Dawley (SD) rats to assess the effects of origin, group housing, or various feeding regimens on longevity. This report describes results of in-life findings pertaining to body weight gain, food consumption, palpable masses, and preliminary analysis of clinical pathology parameters and necropsy observations. The first study compared ad libitum feeding of SD rats from the following suppliers: Charles River Labs (CRL) International Standard (IS) and Original Standard (OS), Ace Animals, Inc., and Harlan Sprague-Dawley, Inc. The second study assessed individual and group housed ad libitum feeding of Purina Certified Rodent Chow 5002 (20% crude protein), and individually housed controlled feeding of either Purina 5002 or Opti-diet (14% crude protein). The in-life phase of the third study has recently been completed. This study compared controlled (5.5 g Purina 5002 biscuit) to ad libitum (Purina 5002) feeding in CRL IS rats. In the supplier study, survival of male rats was markedly greater for CRL (IS) rats when compared to other groups. Body weight gain and food consumption were greatest in the CRL (OS) rats. Increases in cholesterol, triglycerides, urea nitrogen, and gross renal disease were observed in Harlan and Ace SD rats, while CRL rats had a higher incidence of grossly detectable pituitary masses and foci. In the feeding study, controlled feeding significantly increased the survival rate and decreased body weight gain. Single and group housed SD rats fed ad libitum had decreased T4 and markedly higher cholesterol and triglyceride values, when compared to rats fed controlled diets. Survival of IS rats fed a controlled diet was also notably higher than ad libitum-fed IS rats in the third study.

scholarly journals The Biological Activity of Monarda didyma L. Essential Oil and Its Effect as a Diet Supplement in Mice and Broiler Chicken

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3368
Author(s):  
Héloïse Côté ◽  
André Pichette ◽  
Alexis St-Gelais ◽  
Jean Legault
Keyword(s):  
Body Weight ◽  
Essential Oil ◽  
Feed Efficiency ◽  
Body Weight Gain ◽  
Antibacterial Properties ◽  
Resistant Bacteria ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
Monarda Didyma

The use of growth-promoting antibiotics in livestock faces increasing scrutiny and opposition due to concerns about the increased occurrence of antibiotic-resistant bacteria. Alternative solutions are being sought, and plants of Lamiaceae may provide an alternative to synthetic antibiotics in animal nutrition. In this study, we extracted essential oil from Monarda didyma, a member of the Lamiaceae family. We examined the chemical composition of the essential oil and then evaluated the antibacterial, antioxidant, and anti-inflammatory activities of M. didyma essential oil and its main compounds in vitro. We then evaluated the effectiveness of M. didyma essential oil in regard to growth performance, feed efficiency, and mortality in both mice and broilers. Carvacrol (49.03%) was the dominant compound in the essential oil extracts. M. didyma essential oil demonstrated antibacterial properties against Escherichia coli (MIC = 87 µg·mL−1), Staphylococcus aureus (MIC = 47 µg·mL−1), and Clostridium perfringens (MIC = 35 µg·mL−1). Supplementing the diet of mice with essential oil at a concentration of 0.1% significantly increased body weight (+5.4%) and feed efficiency (+18.85%). In broilers, M. didyma essential oil significantly improved body weight gain (2.64%). Our results suggest that adding M. didyma essential oil to the diet of broilers offers a potential substitute for antibiotic growth promoters.

scholarly journals CHRONIC SODIUM CHLORIDE TOXICITY IN THE ALBINO RAT

1953 ◽  
Vol 98 (1) ◽  
pp. 71-80 ◽  
Author(s):  
George R. Meneely ◽  
Robert G. Tucker ◽  
William J. Darby ◽  
Stewart H. Auerbach
Keyword(s):  
Blood Pressure ◽  
Sodium Chloride ◽  
Relative Volume ◽  
Dietary Sodium ◽  
Albino Rats ◽  
Albino Rat ◽  
Positive Linear Correlation ◽  
Ad Libitum ◽  
Histologic Changes ◽  
Dietary Sodium Chloride

Sustained arterial hypertension developed in male, albino rats chronically fed diets rich in sodium chloride with demineralized drinking water available ad libitum. After 12 months of the experimental regimen a positive, linear correlation (r = 0.91) was found between the systolic blood pressure and the concentration of sodium chloride in the diet. A syndrome of edema and renal failure was observed in 18 per cent of the group fed at the level of 7.0 to 9.8 per cent of sodium chloride. Significant histologic changes occurred in the kidneys and certain other organs in rats consuming rations containing these levels of NaCl. The relative volume of the radiosodium space was increased in the rat by high dietary sodium chloride.

scholarly journals PSXII-22 Genomic prediction accuracy for feed efficiency related traits using different pseudo-phenotypes, prediction and validation methods in Nellore cattle

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 245-246
Author(s):  
Cláudio U Magnabosco ◽  
Fernando Lopes ◽  
Valentina Magnabosco ◽  
Raysildo Lobo ◽  
Leticia Pereira ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Genomic Prediction ◽  
Feed Efficiency ◽  
Prediction Accuracy ◽  
Body Weight Gain ◽  
Prediction Methods ◽  
Genomic Breeding ◽  
Validation Population ◽  
Nellore Cattle

Abstract The aim of the study was to evaluate prediction methods, validation approaches and pseudo-phenotypes for the prediction of the genomic breeding values of feed efficiency related traits in Nellore cattle. It used the phenotypic and genotypic information of 4,329 and 3,594 animals, respectively, which were tested for residual feed intake (RFI), dry matter intake (DMI), feed efficiency (FE), feed conversion ratio (FCR), residual body weight gain (RG), and residual intake and body weight gain (RIG). Six prediction methods were used: ssGBLUP, BayesA, BayesB, BayesCπ, BLASSO, and BayesR. Three validation approaches were used: 1) random: where the data was randomly divided into ten subsets and the validation was done in each subset at a time; 2) age: the division into the training (2010 to 2016) and validation population (2017) were based on the year of birth; 3) genetic breeding value (EBV) accuracy: the data was split in the training population being animals with accuracy above 0.45; and validation population those below 0.45. We checked the accuracy and bias of genomic value (GEBV). The results showed that the GEBV accuracy was the highest when the prediction is obtained with ssGBLUP (0.05 to 0.31) (Figure 1). The low heritability obtained, mainly for FE (0.07 ± 0.03) and FCR (0.09 ± 0.03), limited the GEBVs accuracy, which ranged from low to moderate. The regression coefficient estimates were close to 1, and similar between the prediction methods, validation approaches, and pseudo-phenotypes. The cross-validation presented the most accurate predictions ranging from 0.07 to 0.037. The prediction accuracy was higher for phenotype adjusted for fixed effects than for EBV and EBV deregressed (30.0 and 34.3%, respectively). Genomic prediction can provide a reliable estimate of genomic breeding values for RFI, DMI, RG and RGI, as to even say that those traits may have higher genetic gain than FE and FCR.

scholarly journals PERFORMANS BURUNG PUYUH (Coturnix-Coturnix Japonica) FASE GROWER YANG DIBERIKAN TEPUNG MANURE HASIL DEGRADASI LARVA LALAT HITAM (H. illucensL.) MENGGANTIKAN TEPUNG IKAN DALAM RANSUM

ZOOTEC ◽  
2019 ◽  
Vol 39 (2) ◽  
pp. 477
Author(s):  
Yasmira Wenda ◽  
H.J. Manangkot ◽  
J.L.P. Saerang ◽  
Cherlie L. K. Sarajar
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Feed Efficiency ◽  
Fish Meal ◽  
Body Weight Gain ◽  
Coturnix Japonica ◽  
Coturnix Coturnix Japonica ◽  
Black Fly ◽  
Coturnix Coturnix ◽  
Fly Larvae

QUAIL (Coturnix-Coturnix Japonica) GROWER PERFORMANCE SUPPLIED WITH MANURE FLOUR DEGRADED BY BLACK FLY LARVAE (H.ILLUCENS L.) TO REPLACE FISH MEAL. This study aims to determine the manure yield of black fly larvae replacing fish meal in the quail feed of the grower phase. The materials used in this study were 100 unsexed quails, 3 weeks old; the dimension of cage was 40 x 40 x 20 cm. The quails were arranged randomly in each unit. The study was realized by using a completely randomized design (CRD) with 4 treatments and 5 replications. The treatments were R0 = 0% degraded manure flour (MHD); R1 = 4% MHD flour; R2 = 8% MHD flour; R3 = 12% MHD flour. The research variables consisted of ration consumption, body weight gain and feed efficiency. The results obtained showed that treatments provide a very significant influence (P <0.01) on ration consumption. Body weight gain and feed efficiency were not significant different (P> 0.05). The conclusion of this study is that MHD flour up to the 12% level can be used in quail rations replacing fish meal. Keywords: Quail, MHD, Fish meal.

scholarly journals Hatchability, Growth Performance, Feed Efficiency, and Survival of Normal Feathered Local, Sasso-rir and Their F1-cross Chickens Under on-station Management Condition in Southern Ethiopia

2021 ◽  
Author(s):  
shewangizaw woltamo wolde ◽  
Tadele Mirkena ◽  
Aberra Melesse ◽  
Tadelle Dessie ◽  
Solomon Abegaz
Keyword(s):  
Body Weight ◽  
Survival Rate ◽  
Growth Performance ◽  
Feed Efficiency ◽  
Body Weight Gain ◽  
The Body ◽  
Southern Ethiopia ◽  
Feed Conversion ◽  
Egg Hatchability ◽  
F1 Cross

Abstract The Normal Feathered local chicken (LL), Sasso-RIR (SRSR) and their F1-cross (LSR) chickens were hatched to evaluated for egg hatchability, growth performance, feed efficiency and survival rate. After 14-days of brooding, 150 chicks of each genotype were randomly selected and further replicated in to five pens in a deep litter grower house consisting of 30 chicks each in a completely randomized design, and evaluated for a period of 16-weeks. Hatchability of fertile eggs was highest for LL (80.0 %), intermediate for LSR (68.6%) and lowest for SRSR (55.9%) chickens. The body weight (BW) of chicks at 2-weeks of age was 80.0, 76.3 and 61.5 g/bird for SRSR, LSR, and LL, respectively, the latter being the lowest (p<0.05). The respective BW at 8-weeks of age was 732, 587 and 451 g while at 18-weeks it was 1877, 1379 and 1070 g/bird and different from each other (p<0.05). During 3- to 8-weeks and 9- to 18-weeks growth periods, the LL chickens were inferior (p< 0.05) in feed intake (29.7 and 66.9 g/d/bird) whereas the SRSR chickens were superior (p< 0.05) in body weight gain (15.5 and 16.3 g/d/bird) and feed conversion ratio (2.67 and 5.35 g feed/ g gain), respectively. The mortality rate of chicken was not affected by genotypes. It can be concluded that the exotic blood of Sasso-RIR chicken had played a significant role in upgrading the growth rate and market weight of the local Normal Feathered chicken without adverse effect on hatchability, feed efficiency, and survival rate.

Effect of Clomiphene Citrate and Letrozole on Body Weight of female Albino Rat for Consecutive 1-4 Estrous Cycles

2021 ◽  
Vol 15 (11) ◽  
pp. 2938-2941
Author(s):  
Fauzia Qureshi ◽  
Syeda Rizwana Jafri ◽  
Hafiza Sadia Ahmad ◽  
Uzma Waseem ◽  
Ursula Akif ◽  
...  
Keyword(s):  
Body Weight ◽  
Estrous Cycle ◽  
Ovulation Induction ◽  
Clomiphene Citrate ◽  
The Body ◽  
Control Group ◽  
Albino Rats ◽  
Albino Rat ◽  
Estrous Cycles ◽  
Experimental Group

Background: Ovulation induction with clomiphene citrate in women with infertility has been practiced more than 40% years but in infertile patients this treatment plan proved to be ineffective with multiple complication. Body weight plays an important role modulating reproductive development and functioning. Aim: To observe the effects on body weight of female albino rat after use of clomiphene citrate and letrozole for consecutive 1-4 estrous cycles Method: Eighty four adult female Albino rats were equally divided into three groups for this research. Body weight of each rat was measured before and after the experiment. Vaginal smear cytology of each rat was performed to study different phases of estrous cycle. Control group A was given normal saline orally , In Experimental group B rats were given letrozole (Femara) at dose 5mg/kg orally and in Experimental group C rats were given clomiphene citrate at dose 100ug/kg orally. Results: Significant weight gain is observed in rats taking clomiphene citrate as compared to letrozole Conclusion : Comiphene citrate directly affects the body weight which indirectly reduces the ovulation induction and pregnancy rate. Letrozole is good alternate for ovulation induction and for CC resistant patients. Keywords: Estrous cycle, body weight, citrate and letrozole

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