Reorganization in the Cutaneous Core of the Human Thalamic Principal Somatic Sensory Nucleus (Ventral Caudal) in Patients With Dystonia

1999 ◽  
Vol 82 (6) ◽  
pp. 3204-3212 ◽  
Author(s):  
Fred A. Lenz ◽  
Nancy N. Byl
Keyword(s):  
Essential Tremor ◽  
Average Length ◽  
Receptive Fields ◽  
Body Part ◽  
The Body ◽  
Sensory Cortex ◽  
Body Parts ◽  
Primary Sensory Cortex ◽  
Wide Range ◽  
Sensory Nucleus

A wide range of observations suggest that sensory inputs play a significant role in dystonia. For example, the map of the hand representation in the primary sensory cortex (area 3b) is altered in monkeys with dystonia-like movements resulting from overtraining in a gripping task. We investigated whether similar reorganization occurs in the somatic sensory thalamus of patients with dystonia (dystonia patients). We studied recordings of neuronal activity and microstimulation-evoked responses from the cutaneous core of the human principal somatic sensory nucleus (ventral caudal, Vc) of 11 dystonia patients who underwent stereotactic thalamotomy. Fifteen patients with essential tremor who underwent similar procedures were used as controls. The cutaneous core of Vc was defined as the part of the cellular thalamic region where the majority of cells had receptive fields (RFs) to innocuous cutaneous stimuli. The proportion of RFs including multiple parts of the body was greater in dystonia patients (29%) than in patients with essential tremor (11%). Similarly, the percentage of projected fields (PFs) including multiple body parts was higher in dystonia patients (71%) than in patients with essential tremor (41%). A match at a thalamic site was said to occur if the RF and PF at that site included a body part in common. Such matches were significantly less prevalent in dystonia patients (33%) than in patients with essential tremor (58%). The average length of the trajectory where the PF included a consistent, cutaneous RF was significantly longer in patients with dystonia than in control patients with essential tremor. The findings of sensory reorganization in Vc thalamus are congruent with those reported in the somatic sensory cortex of monkeys with dystonia-like movements resulting from overtraining in a gripping task.

scholarly journals Patterns of multisensory facilitation distinguish peripersonal from reaching space

2020 ◽  
Author(s):  
A. Zanini ◽  
I. Patané ◽  
E. Blini ◽  
R. Salemme ◽  
E. Koun ◽  
...  
Keyword(s):  
Receptive Fields ◽  
Theoretical Models ◽  
Body Part ◽  
Peripersonal Space ◽  
The Body ◽  
Theoretical Issue ◽  
Hand Position ◽  
Body Parts ◽  
Arm Reaching ◽  
Whole Space

AbstractPeripersonal space is a multisensory representation of the space near body parts facilitating interactions with the close environment. Studies on non-human and human primates converge in showing that peripersonal space (PPS) is a body-part-centred representation that guides actions. Because of these characteristics, growing confusion conflates peripersonal and arm-reaching space (ARS) that is the space one’s arm can reach. Despite neuroanatomical evidence favors their distinction, whether PPS and ARS tap into different spatial representations remains poorly understood. Here, in five experiments we found that PPS differs from ARS in male and female human participants (N = 120), as evidenced both by their performance and the modeling of their multisensory facilitation. We mapped multisensory facilitation in detecting touches at the hand, placed in different locations radially within ARS. Results showed that 1) PPS is smaller than ARS; 2) multivariate modeling of spatial patterns of multisensory facilitation predicts well the position of the participants’ hand within ARS; 3) multisensory facilitation maps shift according to changes of hand position, revealing hand-centred coding of PPS, but not ARS; and 4) cross-correlation analyses highlight isomorphic multisensory facilitation maps across hand positions, suggesting their functional similarity to the receptive fields of monkeys’ multisensory neurons. In sharp contrast, ARS mapping produced undistinguishable patterns across hand positions, cross-validating the conclusion that PPS and ARS are distinct. These findings call for a refinement of theoretical models of PPS and ARS, which are relevant in constructs as diverse as action and self representation, (social) interpersonal distance, brain-machine interfaces and neuroprosthetics.Significance StatementThe peripersonal space (PPS) is a multisensory interface allowing us to interact with objects in the space close to our body-parts, playing a fundamental role for the defense of the body and for the motor control of actions. Recent research has conflated PPS with the arm-reaching space (ARS), that is whole space reachable by the arm. However, there is actually no evidence supporting this equivalence and the anatomical and functional differences between PPS and ARS have been largely overlooked. In this paper, we frame the theoretical issue in depth, validate a novel methodological paradigm across five experiments, and eventually report robust and cross-validated evidence for the distinction between PPS and ARS, supported by both multivariate and univariate analyses.

Corticostriatal transformations in the primate somatosensory system. Projections from physiologically mapped body-part representations

1991 ◽  
Vol 66 (4) ◽  
pp. 1249-1263 ◽  
Author(s):  
A. W. Flaherty ◽  
A. M. Graybiel
Keyword(s):  
Basal Ganglia ◽  
Receptive Fields ◽  
Somatosensory System ◽  
Body Part ◽  
The Body ◽  
Saimiri Sciureus ◽  
Body Parts ◽  
Cortical Areas ◽  
Somatosensory Information ◽  
Multiple Regions

1. The basal ganglia of primates receive somatosensory input carried largely by corticostriatal fibers. To determine whether map-transformations occur in this corticostriatal system, we investigated how electrophysiologically defined regions of the primary somatosensory cortex (SI) project to the striatum in the squirrel monkey (Saimiri sciureus). Receptive fields in the hand, mouth, and foot representations of cortical areas 3a, 3b, and 1 were mapped by multiunit recording; and small volumes of distinguishable anterograde tracers were injected into different body-part representations in single SI areas. 2. Analysis of labeled projections established that at least four types of systematic remapping occur in the primate corticostriatal system. 1) An area of cortex representing a single body part sends fibers that diverge to innervate multiple regions in the putamen, forming branching, patchy fields that are densest in the lateral putamen. The fields do not form elongated cylindrical forms; rather, they are nearly as extended mediolaterally as they are rostrocaudally. 2) Cortical regions representing hand, mouth, and foot send globally somatotopic, nonoverlapping projections to the putamen, but regions with closely related representations (such as those of the thumb and 5th finger in area 3b) send convergent, overlapping corticostriatal projections. The overlap is fairly precise in the caudal putamen, but in the rostral putamen the densest zones of the projections do not overlap. 3) Regions representing homologous body parts in different SI cortical areas send projections that converge in the putamen. This was true of paired projections from areas 3a and 3b, and from areas 3b and 1. Thus corticostriatal inputs representing distinct somatosensory submodalities can project to the same local regions within the striatum. Convergence is not always complete, however: in the rostral putamen of two cases comparing projections from areas 3a and 1, the densest zones of the projections did not overlap. 4) All projections from SI avoid striosomes and innervate discrete zones within the matrix. 3. These experiments demonstrate that the somatosensory representations of the body are reorganized as they are projected from SI to the somatosensory sector of the primate putamen. This remapping suggests that the striatal representation of the body may be functionally distinct from that of each area of SI. The patchy projections may provide a basis for redistribution of somatosensory information to discrete output systems in the basal ganglia. Transformations in the corticostriatal system could thus be designed for modulating different movement-related programs.

Maximizing Recall of Gruesome Images for Health Effects Advertising: An Experimental Investigation

2010 ◽  
Vol 16 (4) ◽  
pp. 112-121 ◽  
Author(s):  
Brennen W. Mills ◽  
Owen B. J. Carter ◽  
Robert J. Donovan
Keyword(s):  
Experimental Investigation ◽  
Body Part ◽  
The Body ◽  
Advertising Effectiveness ◽  
Body Parts ◽  
Online Study ◽  
Video Clips ◽  
Video Images ◽  
The Impact

The objective of this case study was to experimentally manipulate the impact on arousal and recall of two characteristics frequently occurring in gruesome depictions of body parts in smoking cessation advertisements: the presence or absence of an external physical insult to the body part depicted; whether or not the image contains a clear figure/ground demarcation. Three hundred participants (46% male, 54% female; mean age 27.3 years, SD = 11.4) participated in a two-stage online study wherein they viewed and responded to a series of gruesome 4-s video images. Seventy-two video clips were created to provide a sample of images across the two conditions: physical insult versus no insult and clear figure/ground demarcation versus merged or no clear figure/ground demarcation. In stage one, participants viewed a randomly ordered series of 36 video clips and rated how “confronting” they considered each to be. Seven days later (stage two), to test recall of each video image, participants viewed all 72 clips and were asked to identify those they had seen previously. Images containing a physical insult were consistently rated more confronting and were remembered more accurately than images with no physical insult. Images with a clear figure/ground demarcation were rated as no more confronting but were consistently recalled with greater accuracy than those with unclear figure/ground demarcation. Makers of gruesome health warning television advertisements should incorporate some form of physical insult and use a clear figure/ground demarcation to maximize image recall and subsequent potential advertising effectiveness.

scholarly journals Non-informative vision improves spatial tactile discrimination on the shoulder but does not influence detection sensitivity

2020 ◽  
Vol 238 (12) ◽  
pp. 2865-2875
Author(s):  
Fabrizio Leo ◽  
Sara Nataletti ◽  
Luca Brayda
Keyword(s):  
Tactile Stimulation ◽  
Detection Threshold ◽  
Receptive Fields ◽  
Judgment Task ◽  
The Body ◽  
Detection Sensitivity ◽  
Body Parts ◽  
Tactile Acuity ◽  
Tactile Stimuli ◽  
Numerosity Judgment

Abstract Vision of the body has been reported to improve tactile acuity even when vision is not informative about the actual tactile stimulation. However, it is currently unclear whether this effect is limited to body parts such as hand, forearm or foot that can be normally viewed, or it also generalizes to body locations, such as the shoulder, that are rarely before our own eyes. In this study, subjects consecutively performed a detection threshold task and a numerosity judgment task of tactile stimuli on the shoulder. Meanwhile, they watched either a real-time video showing their shoulder or simply a fixation cross as control condition. We show that non-informative vision improves tactile numerosity judgment which might involve tactile acuity, but not tactile sensitivity. Furthermore, the improvement in tactile accuracy modulated by vision seems to be due to an enhanced ability in discriminating the number of adjacent active electrodes. These results are consistent with the view that bimodal visuotactile neurons sharp tactile receptive fields in an early somatosensory map, probably via top-down modulation of lateral inhibition.

scholarly journals Perception on Prolonged Standing Work in Electronic Manufacturing Company

2018 ◽  
Vol 7 (3.24) ◽  
pp. 44
Author(s):  
Norlizaa Mohamad ◽  
Jafri Mohd Rohani ◽  
Ismail Abdul Rahman ◽  
Anis Amira Mat Zuki
Keyword(s):  
Good Health ◽  
Body Part ◽  
Health Condition ◽  
The Body ◽  
Body Region ◽  
Body Parts ◽  
Prolonged Standing ◽  
Electronic Manufacturing ◽  
Strong Relation ◽  
Ergonomic Interventions

Prolonged standing is one of the common activities in electronic industry as the task requirement. Prolonged standing can cause discomfort on the body of the workers and can lead to injury and occupational disease. The purpose of this study is to investigate standing workers perception on the fatigue and the discomfort on their respective body region for 12 hours working time. The subjects are the 80 workers with a good health condition and at least 6 months tenure. The subject data are collected via questionnaires and Likert scale to define the discomfort, pain, and fatigue. The workers were interviewed regarding their job and perceived fatigue discomfort. The results show the domination of the lower body region with the higher mean at the lower back, legs, and foot ankle. No statistically significant differences were found between the job tenure and body part discomfort pain and fatigue. There is a significant relation between gender and discomfort pain on legs and foot ankle. The result also shows a strong relation between age and the discomfort body parts of thigh and foot ankle. The perceptions of the workers towards discomfort pain and fatigue cause by prolonged standing during performing the task. The results from this study will provide a view for industrial consultants or ergonomist with evidence to support for ergonomic interventions for prolonged standing activity such as job rotation and work-rest schedule. 

Semantics of Hawrami Body Part Terms

2012 ◽  
Vol 16 (3) ◽  
pp. 319-335
Author(s):  
Bistoon Abasi ◽  
Amer Gheitury
Keyword(s):  
Native Speakers ◽  
Body Part ◽  
Field Work ◽  
The Body ◽  
Body Parts ◽  
Human Beings ◽  
Long Time ◽  
Semantic Properties ◽  
Different Levels ◽  
Internal Body

Human body as a universal possession of human beings constitutes an interesting domain where questions regarding semantic categorisations might be sought crosslinguistically. In the following, we will attempt to describe the terms used to refer to the body in Hawrami, an Iranian language spoken in Paveh, a small township in the western province of Kermanshah near Iraqi borders. Due to the scarcity of written material, the inventory of 202 terms referring to external and internal body parts were obtained through a field work, which took a long time, and techniques, such as the “colouring task”, observation and recording the terms as used in ordinary conversations and informal interviews with native speakers. The semantic properties of the terms and the way they are related in a partonymy or locative relationship were also investigated. As far as universals of body part terms are concerned, while conforming to ‘depth principle’ concerning the number of levels each partonomy may consist of, Hawrami violates an important feature of this principle by not allowing transitive relations between different levels of partonomic hierarchies. In addition, Hawrami lacks a term for labelling the ‘whole’.

Body and emotion

2002 ◽  
Vol 10 (1-2) ◽  
pp. 341-367 ◽  
Author(s):  
Ning Yu
Keyword(s):  
Semantic Analysis ◽  
Cultural Models ◽  
Body Part ◽  
The Body ◽  
Body Parts ◽  
Emotional Experiences ◽  
Emotional Symptoms ◽  
Internal Organs ◽  
Internal Body ◽  
External Body

This study presents a semantic analysis of how emotions and emotional experiences are described in Chinese. It focuses on conventionalized expressions in Chinese, namely compounds and idioms, which contain body-part terms. The body-part terms are divided into two classes: those denoting external body parts and those denoting internal body parts or organs. It is found that, with a few exceptions, the expressions involving external body parts are originally metonymic, describing emotions in terms of their externally observable bodily events and processes. However, once conventionalized, these expressions are also used metaphorically regardless of emotional symptoms or gestures. The expressions involving internal organs evoke imaginary bodily images that are primarily metaphorical. It is found that the metaphors, though imaginary in nature, are not really all arbitrary. They seem to have a bodily or psychological basis, although they are inevitably influenced by cultural models.

Determination and transdetermination in imaginal disks of Drosophila (Summary only)

1970 ◽  
Vol 176 (1044) ◽  
pp. 291-293
Keyword(s):  
Single Cells ◽  
Body Part ◽  
Cell Types ◽  
Structural Features ◽  
Theoretical Concept ◽  
Body Cavity ◽  
The Body ◽  
Body Region ◽  
Body Parts ◽  
Imaginal Disks

It is generally assumed that in multicellular organisms the diversity of the different cell types is the result of different gene activity which becomes manifest in the course of development. This theoretical concept of cell differentiation was developed on the basis of results obtained from a relatively small number of suitable experimental systems. One of them comprises the imaginal disks of the fruitfly Drosophila melanogaster . Imaginal disks are larval primordia in holometabolic insects such as flies and mosquitoes, and consist of densely packed populations of morphologically uniform cells. They give rise to defined structures of the adult body (mainly integument), thus replacing parts of the larva which are almost completely histolysed during metamorphosis. The prospective fate of the various imaginal disks can be tested, for example, by transplantation experiments. Individual disks are removed from larvae of a genetically marked strain and transplanted into the body cavity of another larva with which the transplants undergo metamorphosis. The metamorphosed derivatives of the disks are then found in the abdomen of the fly and can be microscopically identified on the basis of the morphology of bristles, hairs and other structural features of the integument. The same method is applied for examination of the developmental performance of disk fragments. From the results of such experiments the following conclusions are drawn: (1) Individual disks of fully grown larvae, that is larvae which are ready to pupate, are determined (programmed) for exactly defined body parts of the adult organism. (2) The individual subregions of such a body part can be localized precisely within a disk. Based on these facts fate maps (anlage plans) can be worked out. (3) From experiments in which different genetically marked disks are intermingled and then transplanted into larvae it is concluded that even single cells are determined for structures of a specific body region.

scholarly journals Patterns of semantic variation differ across body parts: evidence from the Japonic languages

2021 ◽  
Vol 32 (3) ◽  
pp. 455-486 ◽  
Author(s):  
John L. A. Huisman ◽  
Roeland van Hout ◽  
Asifa Majid
Keyword(s):  
Hierarchical Structure ◽  
Body Part ◽  
Naming Task ◽  
The Body ◽  
Body Parts ◽  
Language Family ◽  
The Face ◽  
Lexical Similarity ◽  
Multi Method Approach ◽  
Method Approach

Abstract The human body is central to myriad metaphors, so studying the conceptualisation of the body itself is critical if we are to understand its broader use. One essential but understudied issue is whether languages differ in which body parts they single out for naming. This paper takes a multi-method approach to investigate body part nomenclature within a single language family. Using both a naming task (Study 1) and colouring-in task (Study 2) to collect data from six Japonic languages, we found that lexical similarity for body part terminology was notably differentiated within Japonic, and similar variation was evident in semantics too. Novel application of cluster analysis on naming data revealed a relatively flat hierarchical structure for parts of the face, whereas parts of the body were organised with deeper hierarchical structure. The colouring data revealed that bounded parts show more stability across languages than unbounded parts. Overall, the data reveal there is not a single universal conceptualisation of the body as is often assumed, and that in-depth, multi-method explorations of under-studied languages are urgently required.

scholarly journals Effects of Pause Design on the Decline in Pulling Effort and the Evaluation of Perceived Effort in Pulling Tasks

2021 ◽  
Vol 11 (24) ◽  
pp. 12022
Author(s):  
Cannan Yi ◽  
Fan Tang ◽  
Kaiway Li ◽  
Hong Hu ◽  
Huali Zuo ◽  
...  
Keyword(s):  
Material Handling ◽  
Perceived Exertion ◽  
Body Part ◽  
Exponential Model ◽  
The Body ◽  
Muscular Fatigue ◽  
Body Parts ◽  
Perceived Effort ◽  
Work Related ◽  
Pull Strength

Pulling is one of the manual material handling activities that could lead to work-related musculoskeletal disorders. The objectives of this study were to explore the development of muscular fatigue when performing intermittent pulling tasks and to establish models to predict the pull strength decrease due to performing the tasks. A simulated truck pulling experiment was conducted. Eleven healthy male adults participated. The participants pulled a handle with a load of 40 kg, which resulted in a pulling force of approximately 123 N. The pulling tasks lasted for 9 or 12 min with one, two, or three pauses embedded. The total time period of the embedded pauses was 3 min. The pull strength after each pull and rest was measured. Ratings of the perceived exertion on body parts after each pull were also recorded. The results showed insignificant differences regarding the development of muscular fatigue related to rest frequency. We found that the development of muscular fatigue for pulling tasks with embedded pauses was significantly slower than that for continuous pulls. The forearm had a higher CR-10 score than the other body parts indicating that the forearm was the body part suffering early muscle fatigue. An exponential model was developed to predict the pull strength of the pulling tasks with embedded pauses. This model may be used to assess the developing of muscular fatigue for pulling tasks.

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