scholarly journals Evaluation of Adipokines, Inflammatory Markers, and Sex Hormones in Simple and Complex Breast Cysts’ Fluid

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Paweł Madej ◽  
Grzegorz Franik ◽  
Piotr Kurpas ◽  
Aleksander Owczarek ◽  
Jerzy Chudek ◽  
...  
Keyword(s):  
Serum Levels ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Cyst Fluid ◽  
Local Production ◽  
Sectional Study ◽  
Anthropometric Parameters ◽  
Breast Cyst Fluid ◽  
Cross Sectional ◽  
Breast Cyst

Objective. The aim of the study was to analyze the association between levels of adipokines in the breast cyst fluid and in the circulation in relation to the type of cysts.Material and Measurements. A cross-sectional study involved 86 women with breast cysts (42 with simple cysts and 44 with complex cysts). Plasma and breast cyst fluid leptin, adiponectin, visfatin/NAMPT, resistin, TNF-α, and IL-6 levels, in addition to serum levels of estradiol, progesterone and prolactin, and anthropometric parameters and body composition (by bioimpedance method), were measured.Results. The levels of leptin, adiponectin, and resistin were significantly lower in breast cyst fluid than in plasma regardless of the cyst type. Contrarily, the levels of visfatin/NAMPT and TNF-αwere significantly increased, and IL-6 levels were similar in the breast cyst fluid and plasma in both study groups. There was no correlation between corresponding levels of leptin, adiponectin, resistin, visfatin/NAMPT, TNF-α, and IL-6 in breast cyst fluid and plasma.Conclusions. Higher levels of visfatin/NAMPT and TNF-αin the fluid from simple and complex breast cysts than in plasma suggest that their local production is related to inflammation.

scholarly journals Gut Microbiota Profile and Its Association with Clinical Variables and Dietary Intake in Overweight/Obese and Lean Subjects: A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2032
Author(s):  
Judit Companys ◽  
Maria José Gosalbes ◽  
Laura Pla-Pagà ◽  
Lorena Calderón-Pérez ◽  
Elisabet Llauradó ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Dietary Intake ◽  
Saturated Fatty Acids ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Negatively Associated ◽  
Clinical Variables ◽  
Obese Subjects

We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.

scholarly journals Evaluation of the Blood Level of Adiponectin in Pregnant Adolescents

2021 ◽  
Vol 43 (06) ◽  
pp. 429-435
Author(s):  
Elaine Cristina Rocha Pádua ◽  
Silvia Daher ◽  
Isa de Pádua Cintra Sampaio ◽  
Edward Araujo Júnior ◽  
Cristina Falbo Guazzelli
Keyword(s):  
Serum Levels ◽  
Cross Sectional Study ◽  
Serum Adiponectin ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sectional Study ◽  
Pregnant Adolescents ◽  
Cross Sectional ◽  
Adolescent Group ◽  
Gestational Weight ◽  
Intergroup Comparison

Abstract Objective To evaluate serum levels of adiponectin in pregnant adolescents between 30 and 36 weeks of gestation. Method: A prospective cross-sectional study enrolled 67 normal pregnant women between 30 and 36 weeks of gestation and eutrophic (body mass index [BMI]: 18.5–25 kg/m2), of which 36 were adolescents (< 20 years old) and 31 adults (≥ 20 years old). Serum adiponectin levels were determined by enzyme-linked immunosorbent assay (ELISA). The t-student or Mann-Whitney tests were used for intergroup comparison. Results Pregnant adolescents showed significantly higher serum adiponectin concentrations compared with pregnant adults (p = 0.04). No differences were observed in adiponectin levels in younger pregnant adolescents (< 16 years old) compared with older pregnant adolescents (≥ 16 years old). Adiponectin values were divided into 3 subgroups: < 3,000 ng/mL, between 3,000 and 5,000 ng/mL, and > 5,000 ng/mL. Birthweight was significantly higher in women > 5,000 ng/mL when compared with < 3,000 ng/mL in the adolescent group. No association between pregestational adiponectin levels and BMI, gestational weight gain, and gestational age was observed; however, there was a positive relation with birthweight (p = 0.0239). Conclusion Serum adiponectin values in pregnant adolescents between 30 and 36 weeks of gestation were higher compared with pregnant adults; however, no differences between younger and older pregnant adolescents were observed.

scholarly journals The Relationship between Dioxin-Like Polychlorobiphenyls and IGF-I Serum Levels in Healthy Adults: Evidence from a Cross-Sectional Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. e38213 ◽  
Author(s):  
Octavio P. Luzardo ◽  
Luis Alberto Henríquez-Hernández ◽  
Pilar F. Valerón ◽  
Pedro C. Lara ◽  
Maira Almeida-González ◽  
...  
Keyword(s):  
Serum Levels ◽  
Cross Sectional Study ◽  
Healthy Adults ◽  
Sectional Study ◽  
Cross Sectional ◽  
Igf I ◽  
The Relationship

scholarly journals Thyroid dysfunction and electrocardiographic changes in subjects without arrhythmias: a cross-sectional study of primary healthcare subjects from Copenhagen

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e023854 ◽  
Author(s):  
Bhupendar Tayal ◽  
Claus Graff ◽  
Christian Selmer ◽  
Kristian Hay Kragholm ◽  
Magnus Kihlstrom ◽  
...  
Keyword(s):  
Heart Rate ◽  
Primary Healthcare ◽  
Thyroid Dysfunction ◽  
Low Voltage ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Qtc Interval ◽  
Sectional Study ◽  
Cross Sectional ◽  
Study Population

ObjectiveThe objective of the present study was to investigate associations of both overt and subclinical thyroid dysfunction with common ECG parameters in a large primary healthcare population.DesignCross-sectional study.Setting and participantsThe study population comprised of primary healthcare patients in Copenhagen, Denmark, who had a thyroid function test and an ECG recorded within 7 days of each other between 2001 and 2011.Data sourcesThe Danish National Patient Registry was used to collect information regarding baseline characteristics and important comorbidities.Outcome measure and study groupsCommon ECG parameters were determined using Marquette 12SL software and were compared between the study groups. The study population was divided into five groups based on their thyroid status. Euthyroid subjects served as the reference group in all analyses.ResultsA total of 132 707 patients (age 52±17 years; 50% female) were included. Hyperthyroidism was significantly associated with higher heart rate and prolonged QTc interval with significant interaction with age (p<0.009) and sex (p<0.001). These associations were less pronounced for patients with higher age. Subclinical hyperthyroidism was associated with higher heart rate among females, and a similar trend was observed among males. Hypothyroidism was associated with slower heart rate and shorter QTc but only in women. Moreover, longer P-wave duration, longer PR interval and low voltage were observed in patients with both subclinical and overt hypothyroidism. However, the presence of low voltage was less pronounced with higher age (p=0.001).ConclusionBoth overt and subclinical thyroid disorders were associated with significant changes in important ECG parameters. Age and gender have significant impact on the association of thyroid dysfunction particularly on heart rate and QTc interval.

scholarly journals Conjunctival bacterial flora in diabetic patients

2014 ◽  
Vol 7 (1) ◽  
pp. 5-8 ◽  
Author(s):  
Najmun Nahar ◽  
Shaheda Anwar ◽  
Md Ruhul Amin Miah
Keyword(s):  
Staphylococcus Epidermidis ◽  
Bacterial Flora ◽  
Positive Culture ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
Conjunctival Flora

Conjunctival flora refers to population of microorganisms that dwell within the eyes of healthy individuals and is important in maintaining a healthy ocular surface and normal conjunctival function. Conjunctival flora may be altered by a variety of factors that include age, immunosuppression and geography. Immune function is compromised in diabetes mellitus. The aim of the present study was to see the pattern of conjunctival bacterial flora in diabetic and non-diabetic patients. This cross sectional study was carried out in BSMMU during the period of January 2011 to December 2011. Total 500 conjunctival swabs were collected from both eyes of 50 diabetic patients attending OPD of Endocrinology Department of BSMMU and 200 non-diabetic individuals. Significant number of culture was positive in diabetic patients (64.0%) compared to that of non-diabetic individuals (38.0%). Staphylococcus epidermidis was predominant in both study groups (diabetic vs non-diabetic: 41.3% vs 65.26%). Staphylococcus aureus (15.22%), Escherichia coli (6.52%) and Enterobacter (8.33%) were isolated in diabetic patients. Rate of positive culture in both and single eyes were higher in diabetic (28%, 36.0%) than that of non-diabetic individuals (9.5%, 28.5%). DOI: http://dx.doi.org/10.3329/imcj.v7i1.17698 Ibrahim Med. Coll. J. 2013; 7(1): 5-8

Are serum levels of vitamin D associated with semen quality? Results from a cross-sectional study in young healthy men

2011 ◽  
Vol 95 (3) ◽  
pp. 1000-1004 ◽  
Author(s):  
Cecilia Høst Ramlau-Hansen ◽  
Ulla Kristine Moeller ◽  
Jens Peter Bonde ◽  
Jørn Olsen ◽  
Ane Marie Thulstrup
Keyword(s):  
Vitamin D ◽  
Semen Quality ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Healthy Men
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