scholarly journals MORPHOMETRIC STUDY OF ARTERIES OF THE LOWER JAW REORGANIZATION ASPECTS IN THE SIMULATED POST-RESECTION ARTERIAL PULMONARY HYPERTENSION

2021 ◽  
pp. 17-22
Author(s):  
L. Ya. Posolenyk
Keyword(s):  
Pulmonary Hypertension ◽  
Salivary Gland ◽  
Blood Circulation ◽  
Medical Science ◽  
Mandibular Gland ◽  
The Body ◽  
Venous Stasis ◽  
Small Circle ◽  
Vital Functions ◽  
Arterial Pulmonary Hypertension

Summary. The salivary glands are a special group of secretory organs that play a significant role in dental health of the population, as well as one of the vital functions of the whole human body. With the development of modern medical science, clinicians have often diagnosed salivary gland pathology. One of the most important problems of these pathologies is the study of direct and reverse effects of organs on each other, the principles of their correlations and methods of morphological expression. In recent decades, there has also been an increase of pulmonary lesions, which are accompanied by hypertension in the small circulation and lead to the development of pulmonary heart disease and its decompensation. There are isolated studies on the features of the involvement of the mandibular gland in the pathological process, and only some works reflect the structural changes of the submandibular gland in hemodynamic disorders. The aim of the work – to study morphometric aspects of mandibular arteries reorganization in simulated post-resection arterial pulmonary hypertension. Material and Methods. The arteries of medium (51–125) μm and small (26–50) μm calibers [16] of the mandibular salivary gland of 27 Vietnamese pigs, which were divided into 3 groups, were studied by a complex of histological and morphometric methods. Group 1 included 9 intact animals aged 6.5–7 months, group 2 – 12 pigs of the same age with post-resection pulmonary hypertension and compensated pulmonary heart, group 3 – 6 animals 6.5–7 months with pulmonary hypertension and decompensated pulmonary heart. Results and Discussion. Hypertension (one-month term) in the small circle of blood circulation, which occurred after right-sided pulmonectomy led to the development of pulmonary heart and venous stasis in the organs of the large circle of blood circulation, including in the mandibular gland. At arterial hypertension in a small circle of blood circulation essential structural reorganization of arteries of a mandibular gland is revealed. Although morphological changes were found in the arteries of small caliber of the studied organ and in the decompensation of the pulmonary heart. Conclusions. Our morphological study provided comprehensive information on the features of remodeling of the mandibular arteries in postresection arterial pulmonary hypertension. Prolonged pulmonary hypertension leads to structural rearrangement of the arteries of the middle and small caliber of the mandible, which is characterized by thickening of the membrane, narrowing their lumen and endothelial cells damage, impaired blood supply and hypoxia in the body. The biggest changes are in the arteries of the small caliber of the mandibular gland and in the decompensation of the pulmonary heart in 6.5–7 month old male pigs of the Vietnamese breed.

scholarly journals MEDICAL POSSIBILITIES OF CARBOXYTHERAPY FOR CELLULITE

2019 ◽  
pp. 88-93
Author(s):  
S. M. Drogovoz ◽  
A. V. Kononenko ◽  
H. Zelenkova ◽  
K. V. Drogovoz ◽  
L. B. Ivatsyk
Keyword(s):  
Blood Circulation ◽  
Subcutaneous Fat ◽  
Blood Rheology ◽  
Orange Peel ◽  
The Body ◽  
Venous Stasis ◽  
Hormonal Changes ◽  
Inflammatory Changes ◽  
The Relationship ◽  
Complex Methods

Cellulite is not only an aesthetic and cosmetic defect of the skin, but a signal of violations in the body, the cause of which is an incorrect lifestyle. The number of collagen fibers in the connective tissue decreases markedly, peripheral blood supply is disturbed, various hormonal changes occur, and in combination with malnutrition, a sedentary lifestyle, bad habits (smoking, alcohol abuse), sleep disturbance, frequent stress and sudden changes in body weight can first observe the formation of dimples and bulges (“orange peel”), and with the aggravation of the situation due to lymphostasis, there is an accumulation of toxins and gynoid lipodystrophy occurs with age. The main syndromes that characterize cellulitis: lymphostasis, hypoxia, a violation of the relationship between lipogenesis and lipolysis, non-inflammatory changes in subcutaneous fat, fibrodestruction. Cellulite treatment is carried out by complex methods: pharmaco- and physiotherapeutic, including hormone-correcting, lipocorrection, vasoactive, defibrosing, lifting and others. The lack of monotherapy results can be explained by the complexity of the drug penetration into the "cellulite" zones. The absence of effectiveness of monotherapy stimulates the search for new approaches to treatment. One of the effective methods in complex pharmacotherapy is carboxytherapy. Сarboxytherapy application contributes to the normalization of vascular tone and blood rheology, enhances blood circulation and removes venous stasis; improve oxygenation and trophic tissue, stimulate the processes of neovascularization, lipid metabolism, neocollagenogenesis. As a result of these changes subcutaneous fat cells (cellulite) are destroyed, stagnation is eliminated, and skin elasticity and tone are restored.

scholarly journals Pathomorphogenesis in goats with Coccidiosis

2021 ◽  
Vol 282 ◽  
pp. 03018
Author(s):  
V.M. Usevich ◽  
N.I. Zhenikhova ◽  
M.N. Drozd ◽  
L. Banda
Keyword(s):  
Blood Circulation ◽  
Clinical Laboratory ◽  
The Body ◽  
Urgent Problem ◽  
Research Material ◽  
Vital Functions ◽  
Target Organs ◽  
The World ◽  
Morphological Picture ◽  
Breeding Farms

The problem of the spread of coccidiosis (eimeriosis) in animals is still an urgent problem for veterinary specialists around the world. In this regard, the aim of the study was to study the most complete pathomorphological picture of this disease in goats. The research material was the fallen kids of the Alpine breed. The research was carried out on the basis of one of the goat breeding farms in the Sverdlovsk region. Diagnostics was performed according to clinical, laboratory and pathomorphological studies. Research results. The article describes the morphological picture of pathological changes in the parenchymal and target organs. The scientific novelty lies in the fact that a morphological assessment of changes in target organs, parenchymal organs that provide detoxification function in the body, in the organs of the immune system and in parenchymal organs that perform vital functions in the body of blood circulation and gas exchange has been carried out.

Neutral Lipids of Oats Fruit (Avena Sativa L.)

2020 ◽  
Vol 9 (4) ◽  
pp. 40-43
Author(s):  
N. K. Yuldasheva ◽  
S. D. Gusakova ◽  
D. Kh. Nurullaeva ◽  
N. T. Farmanova ◽  
R. P. Zakirova ◽  
...  
Keyword(s):  
Avena Sativa ◽  
Neutral Lipids ◽  
The Body ◽  
Biologically Active ◽  
Absorption Bands ◽  
Vital Functions ◽  
The Republic ◽  
Living Organisms ◽  
Main Components ◽  
Active Substances

Introduction. Lipids are a widespread group of biologically active substances in nature, making up the bulk of the organic substances of all living organisms. They accumulate in plants in seeds, as well as in fruits and perform a number of vital functions: they are the main components of cell membranes and the energy reserve for the body.Aim. Study of neutral lipids of sown oats (Avena sativa L.).Materials and methods. The objects of the study were fruits (grains) of oats of the sown variety "Tashkent 1," harvested in the Republic of Uzbekistan. Results and discussions. Neutral lipids of oat grains have been found to contain 13 fatty acids with a predominance of the sum of oleic, linolenic and linoleic acids. The total degree of unsaturation was almost 78%. Absorption bands characteristic of these substances were observed in the IR spectrum of MEGC.Conclusion. According to the results of the NL analysis, oat grains consisted of triacylglycerides and free LCDs, which were accompanied by hydrocarbons, phytosterols, triterpenoids and tocopherols.

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

Hypothetical Role of Growth Factors to Reduce Intervertebral Disc Degeneration Significantly through Trained Biological Transformations

2020 ◽  
Vol 26 ◽  
Author(s):  
Cristian Muresanu ◽  
Siva G. Somasundaram ◽  
Sergey V. Vissarionov ◽  
Liliya V. Gavryushova ◽  
Vladimir N. Nikolenko ◽  
...  
Keyword(s):  
Growth Factors ◽  
Blood Circulation ◽  
Seminal Fluid ◽  
Prostate Gland ◽  
The Body ◽  
Personal Experiences ◽  
Biological Transformation ◽  
The Mind

Background: From the evidence of failed injection-based growth factor therapies, it has been proposed that a naturally triggered uninterrupted blood circulation of the growth factors would be superior. Objective: We seek to stimulate discussions and more research about the possibility of using the already available growth factors found in the prostate gland and endometrium by starting a novel educable physiology, known as biological transformations controlled by the mind. Methods: We summarized the stretch-gated ion channel mechanism of the cell membrane, and offer several practical methods that can be applied by anyone, in order to stimulate and enhance the blood circulation of the growth factors from the seminal fluid to sites throughout the body. This details the practical application of our earlier published studies about biological transformations. Results: A previously reported single-patient case study has been extended, adding more from his personal experiences continually improving this novel physiological training and extending the ideas from our earlier findings in detail. Conclusion: The biological transformation findings demonstrate the need additional research to establish the benefits of these natural therapies to repair and rejuvenate tissues affected by various chronic diseases or aging processes.

The history of anabolic steroids and a review of clinical experience with anabolic steroids

1985 ◽  
Vol 110 (3_Suppla) ◽  
pp. S11-S18 ◽  
Author(s):  
H. Kopera
Keyword(s):  
Protein Synthesis ◽  
Protein Metabolism ◽  
Anabolic Steroids ◽  
Muscular Activity ◽  
Living Cells ◽  
Cellular Protein ◽  
Complex Compounds ◽  
The Body ◽  
Anabolic Effect ◽  
Vital Functions

Metabolism is the term employed to embrace the various physical and chemical processes occurring within the tissues upon which the growth and heat production of the body depend and from which the energy for muscular activity, for the maintenance of vital activity and for the maintenance of vital functions is derived (Best & Taylor 1950). The destructive processes by which complex substances are converted by living cells into more simple compounds are called catabolism. Anabolism denotes the constructive processes by which simple substances are converted by living cells into more complex compounds, especially into living matter. Catabolism and anabolism are part of all metabolic processes, the carbohydrate, fat and protein metabolism. The term anabolic refers only to substances that exert an anabolic effect on protein metabolism and are unlikely to cause adverse androgenic effects. They shift the equilibrium between protein synthesis and degradation in the body as a whole in the direction of synthesis, either by promoting protein synthesis or reducing its breakdown. The protein anabolic effect of anabolic steroids is not restricted to single organs but is the result of stimulated biosynthesis of cellular protein in the whole organism.

scholarly journals Mitochondrial Dysfunction Is a Common Denominator Linking Skeletal Muscle Wasting Due to Disease, Aging, and Prolonged Inactivity

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 588
Author(s):  
Hayden W. Hyatt ◽  
Scott K. Powers
Keyword(s):  
Skeletal Muscle ◽  
Mitochondrial Dysfunction ◽  
Chronic Diseases ◽  
Muscle Mass ◽  
Cancer Chemotherapy ◽  
Muscle Wasting ◽  
The Body ◽  
Common Denominator ◽  
Skeletal Muscle Wasting ◽  
Vital Functions

Skeletal muscle is the most abundant tissue in the body and is required for numerous vital functions, including breathing and locomotion. Notably, deterioration of skeletal muscle mass is also highly correlated to mortality in patients suffering from chronic diseases (e.g., cancer). Numerous conditions can promote skeletal muscle wasting, including several chronic diseases, cancer chemotherapy, aging, and prolonged inactivity. Although the mechanisms responsible for this loss of muscle mass is multifactorial, mitochondrial dysfunction is predicted to be a major contributor to muscle wasting in various conditions. This systematic review will highlight the biochemical pathways that have been shown to link mitochondrial dysfunction to skeletal muscle wasting. Importantly, we will discuss the experimental evidence that connects mitochondrial dysfunction to muscle wasting in specific diseases (i.e., cancer and sepsis), aging, cancer chemotherapy, and prolonged muscle inactivity (e.g., limb immobilization). Finally, in hopes of stimulating future research, we conclude with a discussion of important future directions for research in the field of muscle wasting.

Blood Circulation in Insect Wings

1964 ◽  
Vol 96 (1-2) ◽  
pp. 98-98 ◽  
Author(s):  
J. W. Arnold
Keyword(s):  
Blood Circulation ◽  
The Body ◽  
Insect Wings ◽  
Wing Structure ◽  
Wing Veins ◽  
Taxonomic Groups ◽  
Modified Forms ◽  
Surrounding Membrane

Despite their inert appearance, the wings of insects are living appendages and are supplied with blood. This is true for definitive wings as well as for developing ones, and for modified wings such as tegmina, elytra, hemelytra, and halteres as for those that are specialized for flight. Typically the blood circulates only through the wing veins, but in some insects it escapes into the surrounding membrane in certain areas, and in highly modified forms it may be entirely unconfined. The course of circulation is basically the same in the wings of most insects. It flows outward from the body in the costo-medial veins, moves toward the posterior margins via cross-veins, and returns to the body through the cubito-anal veins and axillary cord. However, rhe precise route followed is highly variable concomitant with distinctive patterns of venation in different taxonomic groups and with wing structure. This is illustrated for a number of orders.

How Dead Can You Be?

1975 ◽  
Vol 15 (2) ◽  
pp. 133-146 ◽  
Author(s):  
Adrienne Van Till-D'Aulnis de Bourouill
Keyword(s):  
Brain Function ◽  
Blood Circulation ◽  
Artificial Respiration ◽  
The Body ◽  
Life And Death ◽  
The Public ◽  
Current Usage ◽  
Anglo American ◽  
Legal Security ◽  
Carotid And Vertebral Arteries

Life and death are defined in terms of function. Four groups of abnormal cases of death are specified and differentiated from normal cases. Murder, active euthanasia and cessation of artificial respiration are differentiated on the basis of the interested party, the cause of death and the purpose of the act. Juridical acceptance of this differentiation and terminology makes cessation of artificial respiration lawful, provided the patient had validly refused this treatment or is irreversibly comatose and also respirator-dependent. This would make it unnecessary to redefine death in terms of coma in order to solve legal and practical problems. Such a redefinition is against current usage (coma presumes life) and is the first step on an extremely slippery road; it is only admissible if done by the legislator after extensive public discussion. Disagreement among doctors about the definition and diagnosis of death causes distrust among the public, aggravates the shortage of donor organs and makes legal security an illusion. Three diagnostic ‘schools’ are compared: the Anglo-American (using Harvard's criteria), the French (using Mollaret's coma dépassé) and the Austro-German (using absence of intracranial blood circulation). On grounds of logic only the Austro-German diagnosis is reliable; it is not based on a statistically irreversible absence of outwardly perceptible manifestations of brain function, but proves and documents with certainty the total and irreversible impossibility of brain function. At present this has to be done by bilateral angiography of both carotid and vertebral arteries; if negative concerning the intracranial part, this proves death. In normal cases the traditional criteria may be used; in abnormal cases where no infringement of the body is foreseeable death need not be a certainty in order to stop therapy, provided the patient is irreversibly comatose and also respirator-dependent; in abnormal cases where an infringement is foreseeable death should be proved and documented to make the infringement lawful, apart from other conditions such as consent. Proof can be obtained by the Austro-German method or by discontinuing resuscitation during at least 15 consecutive minutes where this is legally permissible. Most German and Dutch lawyers concerned share this view.

scholarly journals Fenkarol - the first nonsedative antihistamine for parenteral administration

2015 ◽  
Vol 12 (1) ◽  
pp. 54-59
Author(s):  
L V Luss
Keyword(s):  
Clinical Practice ◽  
Allergic Diseases ◽  
Mechanisms Of Action ◽  
The Body ◽  
Parenteral Administration ◽  
Vital Functions ◽  
New Form

In the pathogenesis of various diseases histamine performs an important role relating to one of the most important mediators involved in the regulation of vital functions in the body. Histamine plays a key role in the development of allergic diseases and pseudoallergic reactions. Therefore, in clinical practice, of particular interest are drugs that block the effects of histamine - antihistamines. The lecture highlights mechanisms of action of histamine and indications for antihistamines. Particular attention is given to parenteral forms of antihistamines and benefits of a new form of antihistamines for parenteral use without sedation - fenkarol one of quinuclidine derivatives. Features and advantages of antihistamines - quinuclidine derivatives, first developed in Laboratory of academician M.D. Mashkovsky are presented.

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