Abstract P484: The Role of Excessive Body Weight in Hypertension Risk Among Youth

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Corinna Koebnick ◽  
Margo Sidell ◽  
Matthew Daley ◽  
Xia Li ◽  
Robert Riewerts ◽  
...  
Keyword(s):  
Body Weight ◽  
Hypertension Risk ◽  
Increased Risk ◽  
Excessive Body Weight ◽  
Integrated Health Care System ◽  
Large Cohort Study ◽  
Cox Proportional Hazard Models ◽  
Normal Body Weight ◽  
Baseline Bmi ◽  
Over Time

Objective: To determine the hypertension risk associated with elevated body mass index (BMI) for age in children. Study design: In a retrospective cohort of 706,903 children ages 3-18 years in an integrated health care system in Southern California between 2008 and 2017, Cox proportional hazard models with age as time scale were fitted to assess the risk of hypertension (based on 2017 Blood Pressure Guidelines by the American Academy of Pediatrics using 3 blood pressures of independent consecutive visits), by baseline BMI-for-age category (starting at their first available BMI) and BMI change over time, adjusted for sex, race, socioeconomic status and baseline year. Children were followed up until end of membership, onset of hypertension, death, or end of study period. Results: During 3,121,299 person-years, we identified 19,158 youth with incident hypertension. The adjusted hazard ratio (HR) for hypertension was 0.842 (95%CI 0.755, 0.938) for children with a baseline BMI-for-age <5th percentile, 0.864 (95%CI 0.814, 0.917) for 5-39th percentile, 1.00 (reference) for 40-59th percentile, 1.216 (95%CI 1.153, 1.282) for 60-84th percentile, 1.721 (95%CI 1.629, 1.817) for 85-94th percentile, 2.418 (95%CI 2.261, 2.586) for 95-96th percentile, and 3.816 (95%CI 3.624, 4.019) for ≥97th percentile. The adjusted HR for change in BMI over time was 1.095 (95%CI 1.090, 1.100) per kg/m2. Conclusions: In this large cohort study, we found that even moderate elevations in BMI-for age percentile conferred an increased risk of hypertension in children. Results also indicate an escalation of hypertension risk as BMI increased over time. Our results suggest that normal body weight in children ranging from the 5th to the 85th percentile of BMI-for-age and modest increases in BMI over time may increase the risk for hypertension.

scholarly journals Heart rate features among men of working age with obesity and hypertension

2015 ◽  
Vol 13 (1) ◽  
pp. 30-35
Author(s):  
Nataliya S. Tsyplenkova ◽  
Elena I. Panova
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Body Weight ◽  
Arterial Hypertension ◽  
Left Atrium ◽  
Left Ventricular ◽  
Normal Body ◽  
Increased Risk ◽  
Excessive Body Weight ◽  
Normal Body Weight

Aim. To study features of heart rate of men with arterial hypertension and obesity, to identify factors associated with arrhythmia evolution.Materials and methods. The study included 3 groups of men (with obesity – 98 men, with excessive body weight – 46 men, with normal body weight – 40 men). The comparative analysis of heart rhythm was performed with Resting ECG and Holter ECG monitoring, blood pressure from daily monitoring, echocardiography, blood lipid spectrum, glycaemia. The adiponectin level was analyzed only for group with obesity.Results. Obesity in men with arterial hypertension increases the frequency of arrhythmias of atrial fibrillation (AF) type (15.3% vs. 0% in group with normal body weight, p=0.004) and increases the frequency of ventricular premature beats (VPB) (26.5% in group with obesity vs. 10% in group with normal body weight). We were also able to show the relation between arrhythmia and the severity of obesity. Obesity with arterial hypertension significantly increases the risk of various arrhythmias (more than 6 times for AF risk – p=0.004 and more than 5.31 times for frequent VPB – p=0.026. Risk factors for AF are statistically significant with the presence of obesity: left ventricular (LV) and left atrium (LA) dilation, II–III stage of hypertension and low level of high-density lipoprotein (p0.05). AF risk factors are significant without relation to obesity: left ventricular hypertrophy, dilatation LA, IHD (p0.05). But there is no relation between ischemic heart disease (IHD) and an increased risk of AF evolution. Also no relation was found between sleep apnea syndrome and arrhythmias.Conclusion. Men with excessive body weight or obesity in contrast to men with normal body weight have an increased risk of AF and VPB. Factors directly associated with arrhythmias: heart remodeling (hypertrophy and dilatation of the left ventricular, dilatation of the left atrium), advanced stages of arterial hypertension, dyslipidemia; IHD with obesity associated with risk of VPB and doesn’t affect the AF frequency. 

Relationship between chest mobility and angle of spinal curvateres in the saggital plane

2019 ◽  
Vol 29 (87) ◽  
pp. 39-46
Author(s):  
Marta Bibro ◽  
Łucja Laskowska ◽  
Anita Ziemba ◽  
Agnieszka Jankowicz-Szymańska
Keyword(s):  
Body Weight ◽  
Lumbar Lordosis ◽  
Weight Status ◽  
Sagittal Plane ◽  
Three Dimensional ◽  
Respiratory Muscles ◽  
Body Weight Status ◽  
Significant Difference ◽  
Excessive Body Weight ◽  
Normal Body Weight

Aim: Faulty body postures is a significant problem affecting the reduction of quality of health and life in every age group. Currently, more and more attention is paid to the importance of respiratory muscles, and above all the diaphragm in stabilizing posture. The aim of the study was to determine the relationship between selected features of the position of the torso and chest mobility. Basic procedures: 33 young adults were included in the study. Body weight and height were measured, BMI was calculated and body weight status was determined. The chest circumferences at rest, maximum inspiration and maximum exhalation at three heights was measured. Three-dimensional torso settings were evaluated using the Zebris Pointer Ulrtrasound System. The collected data were subjected to statistical analysis. Results: The majority of examined women had normal body weight, while excessive body weight occurred in nearly 1/3 of men. The most significant difference in the position of the torso was the greater depth of lumbar lordosis in women. A significant correlation was found between the lumbar spine position and the chest circumferences. The results indicate a decrease in chest mobility along with an increase in the depth of lumbar lordosis. Conclusions: Respiratory kinesitherapy should be an important part of the process of correction of spinal shape in sagittal plane.

scholarly journals Oxygen Supply System Management in an Overweight Adult after 12 Months in Antarctica—Study Case

2021 ◽  
Vol 18 (8) ◽  
pp. 4077
Author(s):  
Maria Radziejowska ◽  
Yevgen Moiseyenko ◽  
Paweł Radziejowski ◽  
Michał Zych
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
Respiratory System ◽  
Normal Weight ◽  
System State ◽  
Oxygen Homeostasis ◽  
Overweight Adult ◽  
Excessive Body Weight ◽  
Normal Body Weight ◽  
First Time

The aim of the study was to try to determine the functional state of the respiratory system, i.e., selected parameters and indicators of physiological systems responsible for the supply of oxygen at all stages of its delivery in people as their body weight increases from normal weight to overweight. The studies include an analysis of test results of functional respiratory system state (FSD) indicators of a 30-year-old and 170-cm tall man. Measurements of FSD were conducted two times: the first time before an expedition to Antarctica at 70 kg (normal body weight); the next measurements were taken a year later, after coming back from the expedition, at 82 kg (overweight). When analyzing the functional respiratory system state in terms of the effect of overweight it was found that the maintenance of the oxygen homeostasis in those conditions occurred at the level of a compensated hypoxic state. That is why the decision to engage in physical activity can be made only if we are sure that significant destructive additive effects of both types of hypoxic influences (from excessive body weight and from the physical activity) are not overlapping.

scholarly journals Prevalence of Genu Valgum in Children Aged 10-12 Years with Excessive Body Weight (Overweight/Obesity) in Sanur Kaja Village, Denpasar

2020 ◽  
Vol 5 (2) ◽  
pp. 77-81
Author(s):  
Vidya Rahmayunissa Swandi Putri ◽  
Ni Wayan Tianing ◽  
Agung Wiwiek Indrayani ◽  
Ari Wibawa ◽  
Sayu Aryantari Putri Thanaya
Keyword(s):  
Body Weight ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
Total Sample ◽  
Genu Valgum ◽  
Obese People ◽  
Cross Sectional ◽  
Excessive Body Weight ◽  
Normal Body Weight ◽  
Cross Sectional Design

Background: Overweight/obesity is a global health problem, both in developed and developing countries and the number of overweight/obese people increases every year. Being overweight during childhood increases the risk of obesity in adulthood and can lead to musculoskeletal disorders, one of which is genu valgum. The purpose of this study was to determine the prevalence of genu valgum in children aged 10-12 years who are overweight/obese in Sanur Kaja Village, Denpasar.Methods: This study was an observational study with a cross-sectional design conducted at elementary schools in Sanur Kaja Village in April 2019. The sampling technique used was purposive sampling. A total of 78 children were included in this study. The univariate analysis in this study was genu valgum, overweight/obesity, age, and gender.Result: The prevalence of genu valgum in children aged 10-12 years in Sanur Kaja Village was 46.7% in overweight children and 53.3% in obese children, with 30 people (38.5%) experiencing genu valgum out of the total sample of 78 people (100%).Conclusion: Based on the result of this study, the incidence of genu valgum was higher in children aged 10-12 years who were obese compared to children with overweight body mass index.  It is recommended that children who are obese and overweight to control their eating patterns, maintain normal body weight, and do enough physical activity.

scholarly journals Slipped Capital Femoral Epiphysis (SCFE) Coxa Vara Adolescentium (CVA)

2019 ◽  
Vol 3 (4) ◽  
pp. 1-2
Author(s):  
Gharaibeh A
Keyword(s):  
Body Weight ◽  
Femoral Head ◽  
Growth Plate ◽  
Hip Joint ◽  
Slipped Capital Femoral Epiphysis ◽  
Coxa Vara ◽  
Endocrine Disorders ◽  
Mechanical Forces ◽  
Excessive Body Weight ◽  
Over Time

Slipped fem oral capital epiphysis is considered to be one of the most destructive conditions of hip joint during adolescence. The epiphysolysis of the femoral head was first defined in 1572 by the French surgeon Abrois Paré (1510 - 1590). The first authentic traumati c epiphysesolysis of the femoral head was described by Brousseau in 1867. It was in a 15 - year - old boy with multiple injuries after trauma with heavy carriage. Death occurred in a few hours, and was discovered by post - mortem examination. Complete separation of epiphysis of the femur head was found. The first mention of a non - traumatic form of epiphysolysis occurred in a fourteen years old boy later. In 1881, Fiorani reported fifteen cases of distorted hip joint with impaired adduction in children. He describ ed the deformity as a bend of the proximal part of the femur, which was based on rickets. With a high probability, some individua ls were coxa vara adolescentium . The first complete description of the disease was given by E Müller (1888) in his work “ About the bending of the femoral neck in the growth age ” Coxa vara adolescentium (CVA), epiphysesolysis of femural head or slipped femoral capital epiphysis represents a serious hip disease in the pubescent age at which the femoral proximal growth plate loses it s strength and influence mechanical forces, caused mainly by excessive body weight, the non - traumatic epiphysesolysis will occur. Symptoms like pain and twisting are initially vague, but they tend to escalate over time . The incidence of this disease is 0. 1 per one million, affect male more than female 2:1,4 in the rapid growth period 10 - 16 years old. Childhood obesity is the common cause of Slipped femoral capital epiphysis, then endocrine disorders and Down syndrome. Slipped femoral capital epiphysis has three grades first up to 33 degrees of slippage, second grade from 34 - 50% of slippage and the third degree more than 50%.Slipped femoral capital epiphysis, represents a serious disease of the puberty in the pubescent age at which the femoral proximal growth plate loses its strength and influence mechanical forces, caused mainly by excessive body weight, will occu r non - traumatic epiphysesolysis . Symptoms like pain and limping are initially vague, but they tend to escalate over time .

Viscerally obese women with normal body weight have greater brachial-ankle pulse wave velocity than nonviscerally obese women with excessive body weight

2007 ◽  
Vol 0 (0) ◽  
pp. 070215015809001-??? ◽  
Author(s):  
Ji-Won Lee ◽  
Hye-Ree Lee ◽  
Jae-Yong Shim ◽  
Jee-Aee Im ◽  
Sang-Hwan Kim ◽  
...  
Keyword(s):  
Body Weight ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Obese Women ◽  
Normal Body ◽  
Excessive Body Weight ◽  
Normal Body Weight

Decreased Platelet-Free Dopamine and Unchanged Noradrenaline and Adrenaline in Essential Hypertension

1988 ◽  
Vol 60 (02) ◽  
pp. 251-254 ◽  
Author(s):  
S E Kjeldsen ◽  
K Gjesdal ◽  
P Leren ◽  
I K Eide
Keyword(s):  
Body Weight ◽  
Essential Hypertension ◽  
Blood Platelets ◽  
Plasma Catecholamine ◽  
Catecholamine Synthesis ◽  
Hypertensive Group ◽  
Plasma Catecholamine Concentrations ◽  
Noradrenaline And Adrenaline ◽  
Over Time ◽  
Normotensive Control

SummaryThe content of free-catecholamines in blood platelets is much higher than in plasma and platelet catecholamines must be taken up from plasma, since platelets lack the enzymes for catecholamine synthesis. There is some evidence that platelet catecholamine content under certain circumstances may be an integrated measure of plasma catecholamine concentrations over time. Platelet-free catecholamines were therefore assayed in 18 untreated patients with essential hypertension and in 16 normotensive control subjects. Mean platelet-free dopamine in the hypertensive group was 3.7 ± 0.4 pg/mg platelet weight, i.e. significantly less than the 6.5 ± 0.9 pg/mg found in the normotensive (p <0.005). Platelet contents of noradrenaline and adrenaline did not differ. Decreased platelet-free dopamine and unchanged platelet noradrenaline and adrenaline persisted after adjustment for increased body weight in the hypertensive group. Although the reasons for decreased platelet-free dopamine in the hypertensive group remain unknown, this finding may add to previous result showing facilitated release of granular contents from blood platelets in patients with essential hypertension. Our data do not support platelet levels of free-catecholamines to be a marker of increased sympathetic tone in essential hypertension.

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