Preparation of Poly Lactic-Co-Glycolic Acid-Based Implant Biomaterials and Its Adoption in Restoration of Periodontal Missing Teeth

2021 ◽  
Vol 13 (4) ◽  
pp. 694-704
Author(s):  
Yi Tao ◽  
Hui Dong ◽  
Ying Ma ◽  
Long Han
Keyword(s):  
Glycolic Acid ◽  
Alveolar Bone ◽  
Mechanical Analysis ◽  
Positive Control ◽  
Plga Microspheres ◽  
Missing Teeth ◽  
Initial Release ◽  
Critical Defect ◽  
Mass Ratios

As a commonly used macrolide antibiotic, azithromycin (AZM) has achieved favorable results in the treatment of periodontitis. However, due to the complex environment of the oral cavity, the time of action of topical medication is limited. In this study, AZM-poly lactic-co-glycolic acid (PLGA) microspheres were prepared by the emulsion-solvent evaporation method, whose morphology was observed by scanning electron microscopy. The AZM-PLGA microspheres of different specifications were obtained by using a paddle agitator and a homogenizing agitator, respectively. For the above two different specifications of AZM-PLGA microspheres, the mass ratios of AZM and PLGA were adjusted to 10:100, 15:100, 20:100, and 30:100, respectively. After the mechanical analysis of the microspheres, the slurry-type AZM-PLGA microspheres were taken as the positive control, and the critical defect model of alveolar bone was implanted in New Zealand white rabbits. Then, CT imaging of alveolar bone tissue was obtained at different time points after surgery. Plasma microspheres (20:100) were selected as the implant materials for the restoration of missing teeth in patients with periodontitis. After the test, the results showed that the AZM-PLGA microspheres obtained by the paddle agitator had relatively smaller particle size and smoother surface. The initial release rate of slurry microspheres of different quality was relatively fast, the follow-up rate was relatively stable, and the dosage ratio should not be more than 20%. Slurry microspheres had stronger mechanical properties compared with homogenized microspheres. The osteogenesis observation residues of slurry microspheres with different mass ratios were 15%, 23%, 37%, and 26% at 2–16 weeks, respectively, showing a relatively stable degradation mode. After the five patients with periodontitis participated in the restoration with the use of plasma microspheres (20:100) implants, the periodontal condition was greatly improved. During the observation period, all implants were not loosened and there was no discomfort during percussion.

scholarly journals Immediate Post-Extraction Short Implant Placement with Immediate Loading and without Extraction of an Impacted Maxillary Canine: Two Case Reports

Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2757
Author(s):  
José Antonio Moreno-Rodríguez ◽  
Julia Guerrero-Gironés ◽  
Francisco Javier Rodríguez-Lozano ◽  
Miguel Ramón Pecci-Lloret
Keyword(s):  
Dental Implant ◽  
Alveolar Bone ◽  
Case Reports ◽  
Young Patients ◽  
Aesthetic Result ◽  
First Choice ◽  
Surgical Extraction ◽  
Impacted Canine ◽  
Short Implant

For the treatment of impacted maxillary canines, traction associated with a complete orthodontic treatment is the first choice in young patients. However, in adults, this treatment has a worse prognosis. The surgical extraction of the impacted tooth can result in a series of complications and a compromised alveolar bone integrity, which may lead to the requirement of a bone regeneration/grafting procedure to replace the canine with a dental implant. These case reports aimed to describe an alternative treatment procedure to the surgical extraction of impacted maxillary canines in adults. Following clinical and computerized tomography-scan (CT-Scan) examination, the possibility of maintaining the impacted canine in its position and replacing the temporary canine present in its place with a dental implant was planned. A short dental implant with an immediate provisional crown was placed, without contacting the impacted canine. At 3 months follow-up, a definitive metal-ceramic restoration was placed. Follow-up visits were performed periodically. The implant site showed a physiological soft tissue color and firmness, no marginal bone loss, no infection or inflammation, and an adequate aesthetic result in all follow-up visits. These results suggest that the treatment carried out is a valid option to rehabilitate with an osseointegrated short implant area where a canine is included, as long as there is a sufficient amount of the remaining bone.

scholarly journals Hypodontia of mandibular incisors: considerations on the orthodontic treatment

2018 ◽  
Vol 23 (4) ◽  
pp. 79-87
Author(s):  
Renato Barcellos Rédua ◽  
Paulo César Barbosa Rédua
Keyword(s):  
Case Report ◽  
Treatment Option ◽  
Orthodontic Treatment ◽  
Composite Resin ◽  
Therapeutic Approaches ◽  
Missing Teeth ◽  
Craniofacial Malformation ◽  
Space Closure ◽  
Composite Resin Restorations

ABSTRACT Hypodontia is the most prevalent craniofacial malformation in mankind. It may present a wide variety of manifestations and, depending on the number and location of missing teeth, it may affect the esthetics, mastication, speech and occlusal balance. This paper discusses the therapeutic approaches to solve this condition, describing a case report with hypodontia of one mandibular lateral incisor, which treatment option included space closure at the region of hypodontia associated with composite resin restorations in the mandibular central incisors. The three-year follow-up after treatment revealed occlusal stability, adequate intercuspation in Class I relationship and excellent micro and macroesthetics.

scholarly journals AUTOTRANSPLANTASI GIGI-GIGI IMPAKSI INSISIVUS MAKSILA KANAN DISERTAI KISTA DENTIGEROUS DENGAN PENAMBAHAN GRAFT KOLAGEN KARBONAT APATIT

2018 ◽  
Vol 5 (1) ◽  
pp. 9
Author(s):  
Indah Wulansari ◽  
Maria Goreti Widiastuti ◽  
Prihartiningsih Prihartiningsih
Keyword(s):  
Alveolar Bone ◽  
Dentigerous Cyst ◽  
Apical Part ◽  
Maxillary Incisor ◽  
Carbonate Apatite ◽  
Horizontal Position ◽  
Surgery Patient ◽  
Dentigerous Cysts ◽  
Collagen Graft

Background: Autotransplantation is a surgical movement to reposition teeththat have been erupted, partially erupted or not yet erupted from one place to another in the same individual, either on post-extraction sockets or artifcial sockets made by surgery. Dental folicle from impacted teeth may develope dentigerous cysts that will result in destruction of the jaw bone. There are many factors that influence the success of autotransplantation, one of which is adequate bone support.The purpose of this poster is to present the successful autotransplantation treatment of impacted right maxillary incisor teeth associated with dentigerous cyst and bone support replacement after cyst enucleation using a carbonate apatite collagen graft, GAMACHA®, at RSUP Dr. Sardjito.Case management: A 9-year-old girl, referred to the Oral and MaxillofacialSurgery Department of RSUP Dr. Sardjito with the complaint of right deciduous maxillary incisor persistence. Radiological examination showing persistent of 51 and 52 radices and impaction of teeth 11 and 12 in a horizontal position above radix 53. Also visible radiolucent image with a frm limit around the crown of 11 that supports the image of cyst. This patient performed cyst enucleation under general anesthesia, removal of impacted 11 and 21, followed by an artifcial socket drilling at the alveolar bone that could support all aspects of the root wall although only on the apical part of the tooth root for teeth 11 and 12 placement. Autotransplantation of teeth11 and 12 followed by the application of GAMACHA® and wire fxation, strengthen with acrylic splint.Conclusion: Two years follow up after surgery, patient have no complaintseither from aesthetic or functional and the result of clinical and radiologicalexamination did not found existence of any pathological abnormalities around teeth 11 and 12.

scholarly journals Pragmatic approach to rehabilitate maxillary teeth in aesthetic zone using resin bonded FDP- A case report

2021 ◽  
Vol 7 (4) ◽  
pp. 226-229
Author(s):  
Saurav Kumar ◽  
Harsh Rathee ◽  
Parag Dua
Keyword(s):  
Case Report ◽  
Cost Effective ◽  
Missing Teeth ◽  
Maxillary Central Incisor ◽  
Clinical Complications ◽  
Fixed Partial Denture ◽  
Fixed Dental Prosthesis ◽  
Effective Option ◽  
Aesthetic Results

Resin bonded fixed dental prosthesis offers most conservative and cost-effective option with missing teeth in aesthetic zone specially when an implant prosthesis is not indicated. This case report describes a treatment option for the replacement of a missing maxillary central incisor using a double-retainer resin-bonded fixed partial denture (RBFPD), fabricated from zirconium dioxide (ZrO) ceramic. No clinical complications were observed at follow-up examination after placement of the prosthesis. Satisfactory functional and aesthetic results were achieved. A treatment modality using a ZrO ceramic RBFPD is an alternative for single anterior tooth replacement.

scholarly journals Severe trauma in young permanent tooth: a case report

2020 ◽  
Vol 68 ◽  
Author(s):  
Ana Luiza Costa Silva de OMENA ◽  
Ivana Aguiar FERREIRA ◽  
Claudia Lima RAMAGEM ◽  
Kelly Maria Silva MOREIRA ◽  
Isabela FLORIANO ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Root Resorption ◽  
Traumatic Injury ◽  
Severe Trauma ◽  
Permanent Tooth ◽  
Dental Office ◽  
Severe Traumatic Injury ◽  
Dentoalveolar Trauma ◽  
To Receive

ABSTRACT Dentoalveolar trauma is a severe traumatic injury involving alveolar bone and dental structures. Like any trauma, it can leave irreparable sequelae and even cause tooth loss. The aim of this study is to report on the case of a dentoalveolar trauma in a 10-year-old male patient and the treatment performed with 12-month follow-up. The child had lateral luxation and displacement of teeth 11 and 21 in labial direction after a fall from his own height. The patient was examined at a hospital, received medication and was referred to a dental clinic. At the dental office, the teeth were repositioned, as well as received endodontic treatment and dental reanatomization. Two months after the trauma, root resorption was observed externally, which remained stable for 12 months. It was concluded that post-trauma treatment should be immediate and that follow-up sessions should be done carefully to minimize sequelae and to receive better prognosis.

Effects of 1% and 3% Mobe Leaf Extract Gel on Socket Wound Healing after Tooth Extraction

2021 ◽  
Vol 24 (1) ◽  
pp. 1-5
Author(s):  
Olivia Avriyanti Hanafiah ◽  
Denny Satria ◽  
Avi Syafitri
Keyword(s):  
Wound Healing ◽  
Tooth Extraction ◽  
Leaf Extract ◽  
Alveolar Bone ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
P Value ◽  
Gel Treatment

Tooth extraction is a process of removing teeth from the alveolar bone. In wound healing, fibroblast are very important cells. The main purpose of this study was to determine the effect of mobe leaf 1% and 3% extract gel (Artocarpus lakoocha) on fibroblast proliferation in post extraction tooth socket wound healing. This research used 16 samples of wistar rats, divided into 4 groups, a positive control group, a negative control group and a 1% and 3% mobe leaf extract gel group. The left mandibular incisors were extracted, then 1% and 3% gels of mobe leaf extract were applied on day 1 to day 7. Data analysis was calculated using the Kruskal-Wallis test on clinical data and one way ANOVA test for microscopic. The result of the socket wound healing activity test for a good concentration of mobe leaf extract gel was 3%. This research shows significant resultith p-value of 0.018 (< 0.05) on the closure of the socket wound clinically which means the closure of the wound accelerates because of the mobe leaf 3% extract gel treatment. The distance of fibroblast on microscopically shows significant resultith a p-value of 0.002 (< 0.05), which means that there was an enlargement of the distance fibroblast at the socket wound closure with application of mobe leaf 3% extract gel. From the results of the study it can be concluded that mobe leaf 3% extract gel has the best ability to show acceleration the closure of the socket wound either clinically or microscopically.

Reimplantation of Accidentally Avulsed Permanent Maxillary Anterior Teeth in a 10-Year-Old Girl

2017 ◽  
Vol 7 (3) ◽  
pp. 165-169
Author(s):  
Md Abdul Hannan Sheikh
Keyword(s):  
Case Report ◽  
Normal Saline ◽  
Alveolar Bone ◽  
Tooth Avulsion ◽  
Anterior Teeth ◽  
Long Term Prognosis

Accidental tooth avulsion is a grievous injury and common among the children. Management of avulsed tooth within alveolar socket by reimplantation becomes a challenge for the clinician due to extraoral time and media of transportation. Although the long-term prognosis of reimplantation is poor, the time during which the tooth remain within the arch will guide the development of alveolar bone completely. Moreover, reimplantation will maintain anatomical, functional and esthetic rehabilitation of the patient. In this case report, we present a case of accidental avulsion where teeth were gently rinsed of any debris and placed in normal saline during the examination and preparation of the reimplantation sockets. The teeth were then reimplanted, functionally splinted followed by endodontical treatment. After 12 months follow-up the periodontal space was healed perfectly without any resorption or ankylosis.J Enam Med Col 2017; 7(3): 165-169

scholarly journals Flossing Is Associated with Improved Oral Health in Older Adults

2020 ◽  
Vol 99 (9) ◽  
pp. 1047-1053 ◽  
Author(s):  
J.T. Marchesan ◽  
K.M. Byrd ◽  
K. Moss ◽  
J.S. Preisser ◽  
T. Morelli ◽  
...  
Keyword(s):  
Older Adults ◽  
Periodontal Disease ◽  
Tooth Loss ◽  
Oral Disease ◽  
Categorical Variables ◽  
Older Individuals ◽  
Missing Teeth ◽  
Chi Square ◽  
Hygiene Behavior

The effect of preventive oral habits is largely unexplored in older individuals. The purpose of this study was to evaluate the associations between home use of flossing and prevalence of periodontal disease and caries in older adults. Five-year incident tooth loss was also evaluated. Data on 686 individuals ≥65 y-old from the Piedmont 65+ Dental Study were examined including: 1) interproximal clinical attachment level (iCAL), 2) interproximal probing depth (iPD), 3) numbers of caries, and 4) missing teeth. Flossing behavior was evaluated according to the Periodontal Profile Class (PPC) system. Five-year follow-up data ( n = 375) was evaluated for incident tooth loss. Dichotomous and categorical variables were analyzed using Pearson chi-square tests as well as covariate-adjusted Cochran-Mantel-Haenszel tests. Multiple linear regression compared clinical parameters based on flossing behavior. Elderly flossers had lower (mean, SE) %iCAL≥3 mm (38.2, 2.38 vs. 48.8, 1.56) and %iPD≥4 mm (8.70, 1.41 vs. 14.4, 0.93) compared to nonflossers ( P ≤ 0.005). Flossers showed less coronal caries compared to nonflossers ( P = 0.02). Baseline number of missing teeth (mean, SE) was 11.5 (0.35) in nonflossers compared to 8.6 (0.53) in flossers ( P < 0.0001). Regular dental visitors had lower oral disease levels compared to episodic dental users. The majority of flossers classified into PPC-Stage I (health) whereas nonflossers classified as PPC-Stages V, VI, and VII (disease). At the 5-y follow-up visit, the average tooth loss for flossers was ~1 tooth compared to ~4 teeth lost for nonflossers ( P < 0.0001). Among all teeth, molars showed the highest benefit (>40%) for flossing behavior ( P = 0.0005). In conclusion, the extent of oral disease for older individuals was significantly less in flossers than in nonflossers. Flossers showed less periodontal disease, fewer dental caries, and loss of fewer teeth over a 5-y period. These findings further support flossing as an important oral hygiene behavior to prevent oral disease progression in older adults.

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