scholarly journals The Relation between Body Mass Index, Mental Health, and Functional Disability: A European Population Perspective

2008 ◽  
Vol 53 (10) ◽  
pp. 679-688 ◽  
Author(s):  
Ronny Bruffaerts ◽  
Koen Demyttenaere ◽  
Gemma Vilagut ◽  
Montserat Martinez ◽  
Anke Bonnewyn ◽  
...  

Objective: To examine the association between body mass, mental disorders, and functional disability in the general population of 6 European countries. Method: Data ( n = 21 425) were derived from the European Study on the Epidemiology of Mental Disorders (ESEMeD). The third version of the Composite International Diagnostic Interview was administered to assess mental disorders (mood, anxiety, and alcohol disorders) according to the Diagnostic Statistical Manual of Mental Disorders-fourth edition, body mass index (BMI) (kg/m2, based on self-reported height and weight), and functional disability in the previous 30 days, assessed with the World Health Organization Disablement Assessment Scale—second version. Results: About 3% of the respondents were underweight (BMI < 18.5 kg/m2), 53% had normal weight (BMI 18.5 to 24.9 kg/m2), 33% were overweight (BMI 25 to 29.9 kg/m2), and the remaining 12% met criteria for obesity (BMI > 30.0 kg/m2). Compared with individuals of normal weight, obese individuals were more likely to have mood (OR 1.3; 95%CI, 1.0 to 1.8) or more than one mental disorder (OR 1.4; 95%CI, 1.0 to 2.2). BMI had no impact on work loss days, whereas mental disorders had a considerable effect on work loss days. Conclusions: This is the first cross-national study investigating the role between BMI, mental disorders, and functional disability in the general population. Being overweight or obese is a common condition in the 6 ESEMeD countries. Although there is a moderate association between obesity and mental disorders, BMI did not independently influence functional disability.

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
K Giesinger ◽  
JM Giesinger ◽  
DF Hamilton ◽  
J Rechsteiner ◽  
A Ladurner

Abstract Background Total knee arthroplasty is known to successfully alleviate pain and improve function in endstage knee osteoarthritis. However, there is some controversy with regard to the influence of obesity on clinical benefits after TKA. The aim of this study was to investigate the impact of body mass index (BMI) on improvement in pain, function and general health status following total knee arthroplasty (TKA). Methods A single-centre retrospective analysis of primary TKAs performed between 2006 and 2016 was performed. Data were collected preoperatively and 12-month postoperatively using WOMAC score and EQ-5D. Longitudinal score change was compared across the BMI categories identified by the World Health Organization. Results Data from 1565 patients [mean age 69.1, 62.2% women] were accessed. Weight distribution was: 21.2% BMI < 25.0 kg/m2, 36.9% BMI 25.0–29.9 kg/m2, 27.0% BMI 30.0–34.9 kg/m2, 10.2% BMI 35.0–39.9 kg/m2, and 4.6% BMI ≥ 40.0 kg/m2. All outcome measures improved between preoperative and 12-month follow-up (p < 0.001). In pairwise comparisons against normal weight patients, patients with class I-II obesity showed larger improvement on the WOMAC function and total score. For WOMAC pain improvements were larger for all three obesity classes. Conclusions Post-operative improvement in joint-specific outcomes was larger in obese patients compared to normal weight patients. These findings suggest that obese patients may have the greatest benefits from TKA with regard to function and pain relief one year post-op. Well balanced treatment decisions should fully account for both: Higher benefits in terms of pain relief and function as well as increased potential risks and complications. Trial registration This trial has been registered with the ethics committee of Eastern Switzerland (EKOS; Project-ID: EKOS 2020–00,879)


2013 ◽  
Vol 74 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Mythily Subramaniam ◽  
Louisa Picco ◽  
Vincent He ◽  
Janhavi Ajit Vaingankar ◽  
Edimansyah Abdin ◽  
...  

2021 ◽  
Author(s):  
Koji Takada ◽  
Shinichiro Kashiwagi ◽  
Yuka Asano ◽  
Wataru Goto ◽  
Rika Kouhashi ◽  
...  

Abstract PurposeThe body mass index (BMI) is commonly used as a simple indicator of obesity; patients with early-stage breast cancer who are obese (OB) per BMI measurements have been shown to have high postoperative recurrence and low survival rates. On the other hand, it has been shown that lymphocytes present in the vicinity of malignant growths that are involved in the tumors’ immune responses influence the efficacy chemotherapy. Therefore, we hypothesized that OB patients with breast cancer have a lower density of tumor-infiltrating lymphocytes (TILs), which may influence the therapeutic effect of preoperative chemotherapy (POC). In this study, we measured pretreatment BMI and TILs in patients with breast cancer who underwent POC, examined the correlations between these two factors, and retrospectively analyzed their therapeutic outcomes and prognoses.MethodsThe participants in this study were 421 patients with breast cancer who underwent surgical treatment after POC between February 2007 and January 2019. The patient’s height and weight were measured before POC to calculate the BMI (weight [kg] divided by the square of the height [m2]). According to the World Health Organization categorization, patients who weighed under 18.5 kg/m2 were classified as underweight (UW), those ≥18.5 kg/m2 and >25 kg/m2 were considered normal weight (NW), those ≥25 kg/m2 and <30 kg/m2 were overweight (OW), and those ≥30 kg/m2 were OB. The TILs were those lymphocytes that infiltrated the tumor stroma according to the definition of the International TILs Working Group 2014.ResultsThe median BMI was 21.9 kg/m2 (range, 14.3–38.5 kg/m2); most patients (244; 64.5%) were NW. Among all 378 patients with breast cancer, the TIL density was significantly lower in OB than in NW and OW patients (vs. NW: p=0.001; vs. OW: p=0.003). Furthermore, when examining patients with each breast cancer type individually, the OS of those with TNBC who had low BMIs was significantly poorer than that of their high-BMI counterparts (log rank p=0.031).ConclusionsOur data did not support the hypothesis that obesity affects the tumor immune microenvironment; however, we showed that being UW does affect the tumor immune microenvironment.


2020 ◽  
pp. 2050022
Author(s):  
Myung-Sang Moon ◽  
Bum Soo Kim ◽  
Seong-Tae Kim ◽  
Won Rak Choi ◽  
Hyeon Gyu Lim

Purpose: To assess the preoperative body mass indices of various orthopaedic conditions, there are a few previous nutritional studies in surgical patients, and none did solely the BMI study in general population in Korea. The current authors planned indirectly to evaluate the Koreans’ obesity. Methods: BMI was used to assess the obesity status of the 2063 orthopaedic patients who were subjected to surgeries; 1272 fractures, 490 various elective surgeries, 232 arthroplasties, 59 musculoskeletal infections, and 10 uninfected diabetics, in Jeju island. Results: Among total 2063 patients, 101 patients (4.8%) had underweight, normal weight in 1220 patients (59.1%), overweight in 630 (30.5%), and the so-called “obese” in 124 cases (6.0%). The obesity in detail of each group is listed in Table 2–6. Among 1272 fracture cases, underweight in 79 (6.2%), normal weight in 752 (61.5%), overweight in 345 (27.1%), and overall class I–III obese in 66 (5.1%). 490 elective surgery patients had overweight in 34.5% and obese in 7.1%. The incidences of obesity in each condition are nearly similar, ranging from 5.2% to 7.3% except for the diabetic one. Conclusions: This study on BMI of the orthopaedic patients disclosed that the incidence of obesity is not high yet in Jeju islanders, in spite of the highly improved living standard.


Author(s):  
Hema Malini ◽  
Divya G ◽  
Angelin Dhanalakshmi

Objective: The objective of the study was to determine the prevalence of obesity among the nursing students.Methods: The research approach was quantitative and the research design adopted was cross-sectional research design. The researcher used non- probability purposive sampling technique, and 80 students were selected for the study. World Health Organization body mass index scale was used to assess the prevalence of obesity.Results: Among 80 samples taken for the study 24 (30%) students are in the stage of underweight; 43 (53.8%) students are in normal weight; and 13 (16.2%) are in the stage of pre-obesity.Conclusion: The study findings revealed that 16.2% of the students are in pre-obese stage; hence, awareness regarding complications of obesity may prevent obesity among the nursing students.Keywords: Obesity, Body mass index, Complications, Underweight, Students.


2017 ◽  
Vol 106 (4) ◽  
pp. 305-310 ◽  
Author(s):  
I. Kruhlikava ◽  
J. Kirkegård ◽  
F. V. Mortensen ◽  
D. W. Kjær

Background and Aims: The impact of body mass index on complications and survival in patients undergoing esophagectomy has been extensively studied with conflicting results. In this study, we assess the impact of body mass index on complications and survival following surgery for esophageal and gastro-esophageal-junction cancer in a Danish population. Material and Methods: We identified 285 consecutive patients, who underwent curative-intended treatment for esophageal and gastro-esophageal-junction cancer in the period 2003–2010. We manually reviewed the electronic medical records of all patients included in the study. Body mass index was calculated as weight in kilograms divided by height in meters squared. We grouped patients according to their body mass index, using the World Health Organization definition, as underweight (body mass index < 18.5 kg/m2), normal weight (body mass index: 18.5–24.9 kg/m2), overweight (body mass index: 25–29.9 kg/m2), and obese (body mass index ⩽ 30 kg/m2). Results: Median age at surgery was 65 years (range: 27–84 years), of which 207 (72.6%) were males. Patients with the lowest body mass index and the obese patients seemed to have a higher frequency of minor complications. Anastomotic leakage occurred in less than 10% of the patients and was equally distributed across the groups as was the other major complications. There were no differences in the 1-, 2-, or 5-year survival rates between the four body mass index groups after adjustment for possible confounders. Five-year survival rates for the four body mass index groups were 31.8%, 28.7%, 27.9%, and 26.1%, respectively. Conclusion: Body mass index over 30 or under 18.5 does not seem to affect survival rates or the presence of serious postoperative complications following esophagectomy in patients with esophageal and gastro-esophageal-junction cancers not receiving neoadjuvant oncological treatment.


Author(s):  
Heekyung Lee ◽  
◽  
Jaehoon Oh ◽  
Hyunggoo Kang ◽  
Tae Ho Lim ◽  
...  

Abstract Background The effects of the body mass index (BMI) on outcomes of patients resuscitated from cardiac arrest are controversial. Therefore, the current study investigated the association between the BMI and the favourable neurologic outcomes and survival to discharge of patients resuscitated from out-of-hospital cardiac arrest (OHCA). Methods This multicentre, prospective, nationwide OHCA registry-based study was conducted using data from the Korean Cardiac Arrest Resuscitation Consortium (KoCARC). We enrolled hospitals willing to collect patient height and weight and included patients who survived to the hospital between October 2015 and June 2018. The included patients were categorised into the underweight (< 18.5 kg/m2), normal weight (≥18.5 to < 25 kg/m2), overweight (≥25 to < 30 kg/m2), and obese groups (≥30 kg/m2) according to the BMI per the World Health Organization (WHO) criteria. The primary outcome was a favourable neurologic outcome; the secondary outcome was survival to discharge. Univariate and multivariate analyses were performed to investigate the association between BMI and outcomes. Results Nine hospitals were enrolled; finally, 605 patients were included in our analysis and categorised per the WHO BMI classification. Favourable neurologic outcomes were less frequent in the underweight BMI group than in the other groups (p = 0.002); survival to discharge was not significantly different among the BMI groups (p = 0.110). However, the BMI classification was not associated with favourable neurologic outcomes or survival to discharge after adjustment in the multivariate model. Conclusion The BMI was not independently associated with favourable neurologic and survival outcomes of patients surviving from OHCA.


2021 ◽  
Author(s):  
Koji Takada ◽  
Shinichiro Kashiwagi ◽  
Yuka Asano ◽  
Wataru Goto ◽  
Rika Kouhashi ◽  
...  

Abstract PurposeThe body mass index (BMI) is commonly used as a simple indicator of obesity; patients with early-stage breast cancer who are obese (OB) per BMI measurements have been shown to have high postoperative recurrence and low survival rates. On the other hand, it has been shown that lymphocytes present in the vicinity of malignant growths that are involved in the tumors’ immune responses influence the efficacy chemotherapy. Therefore, we hypothesized that OB patients with breast cancer have a lower density of tumor-infiltrating lymphocytes (TILs), which may influence the therapeutic effect of preoperative chemotherapy (POC). In this study, we measured pretreatment BMI and TILs in patients with breast cancer who underwent POC, examined the correlations between these two factors, and retrospectively analyzed their therapeutic outcomes and prognoses.MethodsThe participants in this study were 421 patients with breast cancer who underwent surgical treatment after POC between February 2007 and January 2019. The patient’s height and weight were measured before POC to calculate the BMI (weight [kg] divided by the square of the height [m2]). According to the World Health Organization categorization, patients who weighed under 18.5 kg/m2 were classified as underweight (UW), those ≥18.5 kg/m2 and >25 kg/m2 were considered normal weight (NW), those ≥25 kg/m2 and <30 kg/m2 were overweight (OW), and those ≥30 kg/m2 were OB. The TILs were those lymphocytes that infiltrated the tumor stroma according to the definition of the International TILs Working Group 2014.ResultsThe median BMI was 21.9 kg/m2 (range, 14.3–38.5 kg/m2); most patients (244; 64.5%) were NW. Among all 378 patients with breast cancer, the TIL density was significantly lower in OB than in NW and OW patients (vs. NW: p=0.001; vs. OW: p=0.003). Furthermore, when examining patients with each breast cancer type individually, the OS of those with TNBC who had low BMIs was significantly poorer than that of their high-BMI counterparts (log rank p=0.031).ConclusionsOur data did not support the hypothesis that obesity affects the tumor immune microenvironment; however, we showed that being UW does affect the tumor immune microenvironment.


PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258395
Author(s):  
Susanna Calling ◽  
Sven-Erik Johansson ◽  
Veronica Milos Nymberg ◽  
Jan Sundquist ◽  
Kristina Sundquist

Objective Obesity is a well-known risk factor for coronary heart disease (CHD), but there is little evidence on the effect of long-term trajectories of body mass index (BMI) over the life course. By using repeated assessments, the aim was to study the risk of CHD in adults during 38 years in different trajectories of BMI. Methods A sample of 2129 men and women, aged 20–59 years at baseline, took part in four repeated interviews between 1980 and 2005. Data on BMI, medical history, lifestyle and socioeconomy were collected. Based on the World Health Organization categories of BMI, life course trajectories of stable normal weight, stable overweight, stable obesity, increasing BMI and fluctuating BMI were created. The individuals were followed through national registers for first hospitalization of CHD (389 events) until the end of 2017, and Hazard Ratios (HRs) were calculated, adjusted for age, sex, socioeconomic factors, lifestyle factors and metabolic comorbidities. Results Stable normal weight in all assessments was the reference group. Those who had an increase in BMI from normal weight in the first assessment to overweight or obesity in later assessments had no increased risk of CHD, HR 1.04 (95% CI: 0.70–1.53). The HR for individuals with fluctuating BMI was 1.25 (0.97–1.61), for stable overweight 1.43 (1.03–1.98), for stable obesity 1.50 (0.92–2.55), and for stable overweight or obesity 1.45 (1.07–1.97), after full adjustments. Conclusion Having a stable overweight or obesity throughout adult life was associated with increased CHD risk but changing from normal weight at baseline to overweight or obesity was not associated with increased CHD risk. Prevention of obesity early in life may be particularly important to reduce CHD risk.


KYAMC Journal ◽  
2017 ◽  
Vol 5 (1) ◽  
pp. 472-475
Author(s):  
Hafiza Akhter ◽  
Nasim Jahan ◽  
Nasim Jahan ◽  
Fazle Mahmud ◽  
Fazle Mahmud ◽  
...  

Background: Body mass index is a valuable tool to assess the nutritional status of an individual. It can be conveniently used to identify those who are underweight, overweight or obese.Objective: To determine the BMI status of medical students.Methods: This cross sectional descriptive study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka from July 2009 to June 2010. A total number of 264 students of both sexes, age ranged from 19 to 21 years were included. A structured questionnaire was used to collect and record the information on age, sex, height in meters and weight in kilograms of each subject. The measurements were taken under supervision using a standardized weighing machine, height measuring scale and measuring tape. Body Mass Index (BMI) was calculated using the formula weight (in kilogram)/ height2 (in meter). Using cut off points from World Health Organization (WHO) criteria BMI was classified. Statistical analysis was done by using SPSS version 16.Result: Mean BMI of male students was 21.64 and of female students was 23.52. In this study, the prevalence of overweight was 20.5% and obesity was 4.5% while 63.6% of the students were within normal weight range and 11.3% were underweight. Among the male students 9.35% were underweight, 76.97% were normal weight, 10.07% were overweight, 3.59% were obese and among female students it was 13.6%, 48.8%, 32% and 4.54% respectively.Conclusion: This study reveals that overweight is a rising problem for both male and female medical students. Moreover, overweight and underweight issues are more common in female students.KYAMC Journal Vol. 5, No.-1, Jul 2014, Page 472-475


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