scholarly journals A Retrospective Study of the Clinical Characteristics Associated with Alcohol and Cannabis use in Early Phase Psychosis

2020 ◽  
Vol 65 (6) ◽  
pp. 426-435 ◽  
Author(s):  
Jacob Cookey ◽  
Jacob McGavin ◽  
Candice E. Crocker ◽  
Kara Matheson ◽  
Sherry H. Stewart ◽  
...  
Keyword(s):  
Trait Anxiety ◽  
Early Phase ◽  
Clinical Characteristics ◽  
Alcohol Misuse ◽  
Treatment Guidelines ◽  
Group Differences ◽  
Psychotic Symptoms ◽  
High Alcohol ◽  
Occupational Functioning ◽  
Cross Sectional

Objective: Alcohol and cannabis misuse are common in patients with early phase psychosis (EPP); however, research has tended to focus primarily on cannabis misuse and EPP outcomes, with a relative lack of data on alcohol misuse. This retrospective cross-sectional EPP study investigated the relationship between cannabis, alcohol, and cannabis combined with alcohol misuse, on age, gender, psychotic, depressive and anxiety symptom severity, and social/occupational functioning, at entry to service. Methods: Two-hundred and sixty-four EPP patients were divided into 4 groups based on substance use measured by the Alcohol, Smoking and Substance Involvement Screening Test: (1) no to low-level cannabis and alcohol misuse (LU), (2) moderate to high alcohol misuse only (AU), (3) moderate to high cannabis misuse only (CU), and (4) moderate to high alcohol and cannabis misuse (AU + CU). Results: We found significant between group differences in age (with the AU group being the oldest and AU + CU group the youngest) as well as gender (with the CU group having the highest percentage of men). There were also group differences in positive psychotic symptoms (lowest in AU group), trait anxiety (highest in AU + CU group), and social/occupational functioning (highest in AU group). Further regression analyses revealed a particularly strong relationship between AU + CU group and trait anxiety (3-fold increased odds of clinical trait anxiety for combined misuse of alcohol and cannabis compared to non/low users). Conclusions: This study demonstrates the unique demographic and clinical characteristics found in the EPP population at entry to care associated with alcohol and cannabis misuse both separately and in combination. This work highlights the importance of including the assessment of alcohol misuse in addition to cannabis misuse in future treatment guidelines and research.

scholarly journals Clinical characteristics and cytokine changes in children with pneumonia requiring mechanical ventilation

2017 ◽  
Vol 45 (6) ◽  
pp. 1805-1817 ◽  
Author(s):  
Thuy Nguyen Thi Dieu ◽  
An Pham Nhat ◽  
Timothy J Craig ◽  
Sy Duong-Quy
Keyword(s):  
Mechanical Ventilation ◽  
Clinical Characteristics ◽  
Ventilatory Support ◽  
Severe Pneumonia ◽  
Cross Sectional Study ◽  
Group Differences ◽  
Age Group ◽  
Cross Sectional ◽  
Cytokine Levels ◽  
Macrophage Colony

Objective To assess clinical characteristics and cytokine levels in children with severe pneumonia who required ventilatory support. Methods In this prospective, descriptive, cross-sectional study, blood and endotracheal fluid samples were obtained from patients with severe pneumonia, aged <5 years, within 24 h following intubation. Blood samples were also obtained from age-matched healthy controls. Cytokine levels were investigated using flow cytometry-assisted immunoassay. Results Forty-five patients with severe pneumonia requiring mechanical ventilation (aged 10 ± 5 months) and 35 healthy age-matched controls were included. Patients with severe pneumonia had significantly increased serum interleukin (IL)-6, IL-8, and granulocyte/macrophage colony-stimulating factor concentrations compared with controls (80.84 pg/ml versus 2.06 pg/ml, 90.03 pg/ml versus 6.62 pg/ml, and 115.58 pg/ml versus 11.47 pg/ml, respectively). In the severe pneumonia group, serum IL-10 levels were significantly higher in patients aged <6 months versus those aged 6–12 months. Age-group differences in serum cytokine levels did not correspond to age-group differences in endotracheal-fluid cytokine levels. Serum IL-6 levels were significantly higher in patients who subsequently died versus those who survived (267.12 pg/ml versus 20.75 pg/ml, respectively). Conclusion High IL-6 concentrations were associated with mortality in patients <5 years of age with severe pneumonia requiring mechanical ventilation.

scholarly journals Quality of life, its factors, and sociodemographic characteristics of Polish women with lipedema

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Joanna E. Dudek ◽  
Wojciech Białaszek ◽  
Marcin Gabriel
Keyword(s):  
Quality Of Life ◽  
Health Professionals ◽  
Clinical Characteristics ◽  
Online Survey ◽  
Treatment Guidelines ◽  
Diagnostic Tools ◽  
Depression Symptom ◽  
Cross Sectional ◽  
Medical Health

Abstract Background Lipedema is a type of subcutaneous adipose tissue disorder that affects mainly women. Its main symptom is bilateral fat accumulation on the extremities with associated pain in the affected areas. Despite growing interest in lipedema among patients and medical health professionals, lipedema is still often misdiagnosed, misunderstood, and mistreated. To promote better understanding of lipedema, we aimed to investigate factors related to the quality of life and describe selected sociodemographic and clinical characteristics of women with lipedema in Poland. Methods We conducted a cross-sectional online survey that was completed by 98 women with lipedema. The participants responded to questionnaires regarding quality of life, sociodemographic and clinical characteristics, and depression symptom severity. Results The participants reported low quality of life and high severity of depressive symptoms. The more severe the symptoms related to pain, heaviness, and swelling, the lower the quality of life. Further analyses showed that depression severity mediated this relationship. Conclusions The current study provides initial information on screening questions, lipedema symptoms, and comorbidities, pointing to the areas needing in-depth investigation. Further steps to improve quality of life in women with lipedema and to reduce health costs should include the education of medical health professionals, using diagnostic tools that allow for differentiation among diagnoses and precise health risk assessment, and creating Polish treatment guidelines for lipedema.

Quantitative Clinical Characteristics of 53 Patients with MPS VII: A Cross-Sectional Analysis

2017 ◽  
Vol 48 (S 01) ◽  
pp. S1-S45
Author(s):  
M. Zielonka ◽  
S. Garbade ◽  
S. Kölker ◽  
G. Hoffmann ◽  
M. Ries
Keyword(s):  
Clinical Characteristics ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Mps Vii ◽  
Sectional Analysis

Socio-demographic and Clinical Characteristics of Patient with Thyroid Cancer

2020 ◽  
Vol 11 (1) ◽  
pp. 54-58
Author(s):  
AKM Farhad Hossain ◽  
Md Mahmudur Rahman Siddiqui ◽  
Sayada Fatema Khatun
Keyword(s):  
Public Health ◽  
Thyroid Cancer ◽  
Clinical Characteristics ◽  
Family Income ◽  
Ethical Issues ◽  
Endocrine System ◽  
Public Health Problem ◽  
Follicular Carcinoma ◽  
Public Health Issue ◽  
Cross Sectional

Background: Thyroid cancer is the most common malignant disease in endocrine system. It is an emerging public health issue associated with burden on the family, community and the nation. The aim of this study is to determine the socio-demographic and clinical characteristics of patient with thyroid cancer attending in tertiary hospital. Methods: This cross sectional study was conducted among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. The subjects were selected purposively following specific selection criteria and maintaining ethical issues. Data were collected by face to face interview using a semi-structured questionnaire and checklist. Data were analyzed by the statistical package for the social science (SPSS) version 23. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (Range 14-70 years) and mean (± SD) monthly family income was Tk. 17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Various clinical presentations included visible neck swelling in 225 (91.5%), swollen lymph node in 103 (41.9%), pain 90 (36.6%), Difficulties in swallowing 87 (35.4%), Hoarseness of voice in 141 (57.3%), cough along with swelling 47(19.1%), Difficulties in breathing due to swelling in 13(5.3%) of the patients. Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients in 3rd and 4th decades of life. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 54-58

DIFFERENCES IN CLINICAL CHARACTERISTICS BETWEEN BIPOLAR PATIENTS WITH CURRENT PSYCHOTIC SYMPTOMS AND THOSE WHO HAVE NEVER BEEN PSYCHOTIC

2018 ◽  
Vol 30 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Zsuzsanna Belteczki ◽  
◽  
Zoltan Rihmer ◽  
Julia Ujvari ◽  
Dorian A. Lamis ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Psychotic Symptoms ◽  
Bipolar Patients

scholarly journals Personality Prototypes in People with Type 1 Diabetes and Their Relationship with Adherence

2021 ◽  
Vol 18 (9) ◽  
pp. 4818
Author(s):  
Carmen Sánchez-Urbano ◽  
María J. Pino ◽  
Carlos Herruzo
Keyword(s):  
Type 1 Diabetes ◽  
Personality Traits ◽  
Psychological Health ◽  
Treatment Guidelines ◽  
Control Sample ◽  
Self Care ◽  
Self Report ◽  
Cross Sectional ◽  
Care Guidelines

Type 1 diabetes (Dm1) is a chronic endocrine and metabolic disease that affects the whole person and requires active, decisive treatment. However, personality traits may influence a patient’s adherence to treatment guidelines. The objective of this work is firstly to identify the 3 Asendorpf personality prototypes (resilient, undercontrolled and overcontrolled) in a sample of Dm1 individuals and determine whether there are any differences in comparison with a control sample; and, secondly, to study their association with adherence to self-care guidelines using both physiological indicators (HbA1C) and self-report measures. To achieve these objectives, a descriptive cross-sectional study was carried out. The sample comprised 294 participants, of whom 104 were people with Dm1 and 190 were controls. The participants, aged between 14 and 34 years, were classified by their scores in NEO-FFI-R, according to the personality characteristics inherent to Asendorpf’s prototypes. Asendorpf’s 3 prototypical personality patterns were found both in the group of people with Dm1 and in the control sample. These patterns showed different degrees of association with adherence to self-care guidelines for this disease and with psychological health factors. Importance should therefore be attached to the personality traits and Asendorpf prototypes of people with Dm1 when proposing interventions to address medical, psychological, and behavioral aspects.

scholarly journals The Association of Social Support and Symptomatic Remission among Community-Dwelling Schizophrenia Patients: A Cross-Sectional Study

2021 ◽  
Vol 18 (8) ◽  
pp. 3977
Author(s):  
Chi-Hsuan Fan ◽  
Shih-Chieh Hsu ◽  
Fei-Hsiu Hsiao ◽  
Chia-Ming Chang ◽  
Chia-Yih Liu ◽  
...  
Keyword(s):  
Social Support ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Psychotic Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Remission Status ◽  
Remission Rates ◽  
Symptomatic Remission

Schizophrenia is a mental disease that often leads to chronicity. Social support could reduce the severity of psychotic symptoms; therefore, its influence on remission should be examined. This study investigated the remission rates in community-dwelling schizophrenia patients and examined the association between social support and remission status. A cross-sectional study was conducted in 129 schizophrenia patients in Taiwan. Remission rates were evaluated, and the level of social support, clinical characteristics, sociodemographic variables, and healthy lifestyle status were compared between the remission and nonremission groups. The association between social support and remission was analyzed after adjusting for confounding factors. The mean illness duration is 12.9 years. More than 95% of the participants lived with their families, 63% were unemployed, and 43% achieved remission. Higher social support was observed in the remission group, and a significant correlation was observed between family domain of social support and remission status. Family support was a protective factor of symptomatic remission in community-dwelling schizophrenia patients in Taiwan. The results reflect the effects of a family-centered culture on patients during illness. Consequently, reinforcing family relationships and the capacity of families to manage the symptoms of patients and providing support to families are recommended.

Psychotic symptoms in mass shootings v. mass murders not involving firearms: findings from the Columbia mass murder database

2021 ◽  
pp. 1-9
Author(s):  
Gary Brucato ◽  
Paul S. Appelbaum ◽  
Hannah Hesson ◽  
Eileen A. Shea ◽  
Gabriella Dishy ◽  
...  
Keyword(s):  
Mental Illness ◽  
Drug Use ◽  
Legal History ◽  
Alcohol Misuse ◽  
Mass Murder ◽  
Health Concern ◽  
Psychotic Symptoms ◽  
Mass Shootings ◽  
Fully Automatic ◽  
Mass Murders

Abstract Background Mass shootings account for a small fraction of annual worldwide murders, yet disproportionately affect society and influence policy. Evidence suggesting a link between mass shootings and severe mental illness (i.e. involving psychosis) is often misrepresented, generating stigma. Thus, the actual prevalence constitutes a key public health concern. Methods We examined global personal-cause mass murders from 1900 to 2019, amassed by review of 14 785 murders publicly described in English in print or online, and collected information regarding perpetrator, demographics, legal history, drug use and alcohol misuse, and history of symptoms of psychiatric or neurologic illness using standardized methods. We distinguished whether firearms were or were not used, and, if so, the type (non-automatic v. semi- or fully-automatic). Results We identified 1315 mass murders, 65% of which involved firearms. Lifetime psychotic symptoms were noted among 11% of perpetrators, consistent with previous reports, including 18% of mass murderers who did not use firearms and 8% of those who did (χ2 = 28.0, p < 0.01). US-based mass shooters were more likely to have legal histories, use recreational drugs or misuse alcohol, or have histories of non-psychotic psychiatric or neurologic symptoms. US-based mass shooters with symptoms of any psychiatric or neurologic illness more frequently used semi-or fully-automatic firearms. Conclusions These results suggest that policies aimed at preventing mass shootings by focusing on serious mental illness, characterized by psychotic symptoms, may have limited impact. Policies such as those targeting firearm access, recreational drug use and alcohol misuse, legal history, and non-psychotic psychopathology might yield more substantial results.

scholarly journals Características sociodemográficas e clínicas de pacientes portadoras de cardiomiopatia periparto: contribuições para a enfermagem [Sociodemographic and clinical characteristics of peripartum cardiomyopathy patients: contributions to nursing] [Características sociodemográficas y clínicas de pacientes portadoras de cardiomiopatía periparto: contribuciones a la enfermería]

2018 ◽  
Vol 26 ◽  
pp. e32033
Author(s):  
Tamires Grama dos Santos ◽  
Karla Biancha Silva de Andrade ◽  
Flávia Giron Camerini ◽  
Andrezza Serpa Franco ◽  
Ana Lúcia Cascardo Marins ◽  
...  
Keyword(s):  
Skin Color ◽  
Rio De Janeiro ◽  
Clinical Characteristics ◽  
Peripartum Cardiomyopathy ◽  
University Hospital ◽  
Respiratory Pattern ◽  
Cross Sectional ◽  
Documentary Analysis ◽  
Cardiac Intensive Care ◽  
Janeiro State

Objetivo: identificar as características clínicas e sociodemográficas das pacientes portadoras de cardiomiopatia periparto em unidade cardiointensiva de um hospital universitário no Estado do Rio de Janeiro. Método: estudo quantitativo, transversal, de análise documental em cinco prontuários, entre janeiro de 2014 a dezembro de 2016, obedecendo aos critérios preestabelecidos de inclusão e exclusão e iniciado após aprovação do Comitê de Ética e Pesquisa. Os dados foram coletados mediante um formulário próprio, tabulados em planilhas eletrônicas e analisados através de estatística descritiva simples. Resultados: houve predominância de idade entre 26-35 anos – 4 (80%), multíparas, etnia parda, internação para pós-operatório de parto cesárea – 4 (80%), internação inferior a 2 semanas 4 (80%). Dentre os problemas de enfermagem encontrados, estão o débito cardíaco diminuído e padrão respiratório ineficaz. Conclusão: divulgar as características sociodemográficas e clínicas dessa clientela pode ajudar a delimitar alguns problemas de enfermagem representativos nessa população.ABSTRACTObjective: to identify the clinical and sociodemographic characteristics of patients with peripartum cardiomyopathy in a cardiac intensive care unit of a university hospital in Rio de Janeiro State. Method: this quantitative, cross-sectional, documentary analysis studied five medical records, between January 2014 and December 2016, according to pre-established inclusion and exclusion criteria, after approval by the research ethics committee. Data were collected using a specific form, tabulated in electronic spreadsheets, and analyzed by simple descriptive statistics. Results: subjects were aged predominantly 26-35 years (4; 80%), multiparous, skin color brown, admitted for caesarean section postoperative care (4; 80%), and for less than 2 weeks (4; 80%). The nursing problems encountered included decreased cardiac output and ineffective respiratory pattern. Conclusion: disclosure of this clientele’s sociodemographic and clinical characteristics can help to delimit some representative nursing problems in this population.RESUMENObjetivo: identificar las características clínicas y sociodemográficas de las pacientes portadoras cardiomiopatía periparto en una unidad de cuidados intensivos coronarios de un hospital universitario en el Estado de Río de Janeiro. Método: estudio cuantitativo, transversal, de análisis documental en cinco historias clínicas, entre enero de 2014 y diciembre de 2016, obedeciendo a los criterios preestablecidos de inclusión y exclusión e iniciado tras la aprobación del Comité de Ética en Investigación. Los datos fueron recolectados a través de un formulario propio, tabulados en planillas electrónicas y analizados a través de estadística descriptiva simple Resultados: hubo predominancia de edad entre 26 y 35 años – 4 (80%), multíparas, etnia parda, internación para postoperatorio de parto cesárea - 4 (80%), internación inferior a 2 semanas – 4 (80%). Entre los problemas de enfermería encontrados, están el débito cardíaco disminuido y el patrón respiratorio ineficaz. Conclusión: divulgar las características sociodemográficas y clínicas de esa clientela puede ayudar a delimitar algunos problemas de enfermería representativos en esa población.

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