scholarly journals Insertion/deletion polymorphism of angiotensin-1 converting enzyme is associated with metabolic syndrome in Hungarian adults

2011 ◽  
Vol 12 (4) ◽  
pp. 531-538 ◽  
Author(s):  
Szilvia Fiatal ◽  
Endre Szigethy ◽  
György Széles ◽  
Réka Tóth ◽  
Róza Ádány
Keyword(s):  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Sex Distribution ◽  
Cross Sectional ◽  
Low Hdl ◽  
Study Population ◽  
Hungarian Population ◽  
M235t Polymorphism

The aim of our study was to evaluate whether any association exists between metabolic syndrome (MS) and ACE I/D and AGT M235T gene polymorphisms in Hungarians as an example of European Caucasian population. Study subjects of our cross-sectional study were recruited from the Hungarian General Practitioners’ Morbidity Sentinel Stations Program. The study population ( n = 1762) approximates very well the age and sex distribution of the general Hungarian population. MS was defined according to the latest diagnostic criteria proposed by the International Diabetes Federation. The frequency of DD genotype (31.36% vs. 25.42%, p = 0.006) and the frequency of D allele (0.56 vs. 0.51, p = 0.006) were significantly higher in the metabolic group than in the non-metabolic group. The distribution of the AGT M235T polymorphism was similar in each group investigated. Association was shown in the case of patients in whom central obesity was combined with elevated TG and low HDL cholesterol level ( p = 0.024 and p = 0.022). It suggests that ACE I/D polymorphism is likely to be involved in lipid metabolism.

Prevalence of Abdominal Obesity and Metabolic Syndrome in Children and Adolescents: A Community Based Cross-Sectional Study

2020 ◽  
Author(s):  
Nastaran AHMADI ◽  
Seyed Mahmood SADR ◽  
Mohammad Reza MOHAMMADI ◽  
Masoud MIRZAEI ◽  
Amir Hooshang MEHRPARVAR ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Children And Adolescents ◽  
Abdominal Obesity ◽  
Adult Population ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
National Study ◽  
Cross Sectional ◽  
Common Component ◽  
Low Hdl

Background: Although the prevalence of abdominal obesity and metabolic syndrome has been widely studied in the adult population, little is known about it in children and adolescents especially in developing countries. This study aimed to determine the prevalence of abdominal obesity and metabolic syndrome among children and adolescents in Yazd Greater Area, Iran; over the period of 2016-2017. Methods: This study was part of a larger national study with a cross-sectional design. Using multistage cluster random sampling method, 1035 children, and adolescents of both sexes aged 6-18 yr were randomly selected from rural and urban districts in Yazd Greater Area, Iran. Components of metabolic syndrome, and anthropometry measured in the standard situation. Results: The prevalence of abdominal obesity in children 6-10 yr old was 13.2% in boys versus 24.7% in girls. The overall prevalence of metabolic syndrome according to International Diabetes Federation (IDF) criteria in adolescents aged 10-18 yr old was 7.6% (9.4% in boys). The most prevalent metabolic syndrome components were low HDL-cholesterol (56.2%) and abdominal obesity (27.8%). Conclusion: Comparatively, the prevalence of metabolic syndrome in Yazd is high. Low HDL-cholesterol levels and abdominal obesity were the most common component, and family history of heart disease, BMI, and male gender were the main determinants of metabolic syndrome in adolescents.

scholarly journals Correlation of Uric Acid Levels and Parameters of Metabolic Syndrome

2017 ◽  
pp. 481-487 ◽  
Author(s):  
L. CIBIČKOVÁ ◽  
K. LANGOVÁ ◽  
H. VAVERKOVÁ ◽  
V. KUBÍČKOVÁ ◽  
D. KARÁSEK
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Hypertriglyceridemic Waist ◽  
Low Hdl ◽  
Hypertriglyceridemic Waist Phenotype

Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype. We found that levels of uric acid are associated with parameters of metabolic syndrome. Specifically, dyslipidemia characteristic for metabolic syndrome (low HDL cholesterol and high triglycerides) correlates better with uric acid levels than parameters of insulin resistance. Also waist circumference correlates better with uric acid levels than body mass index. Patients with hypertriglyceridemic waist phenotype had higher levels of uric acid when compared with patients without this phenotype. Serum uric acid levels are even in low levels linearly correlated with parameters of metabolic syndrome (better with typical lipid characteristics than with parameters of insulin resistance) and could be associated with higher cardiovascular risk.

scholarly journals Psychosocial job conditions and biomarkers of cardiovascular disease: A cross-sectional study in the Swedish CArdioPulmonary bioImage Study (SCAPIS)

2022 ◽  
pp. 140349482110640
Author(s):  
Mia Söderberg ◽  
Helena Eriksson ◽  
Kjell Torén ◽  
Göran Bergström ◽  
Eva Andersson ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Ldl Cholesterol ◽  
High Strain ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Diastolic Hypertension ◽  
Low Hdl ◽  
Job Conditions

Aims: The aim of this study was to investigate associations between psychosocial work exposure and the presence of biological and imaging biomarkers of cardiovascular disease. Methods: This cross-sectional study was conducted in a sub-cohort of the Swedish CArdioPulmonary bioImage Study (SCAPIS). Psychosocial exposure was evaluated with the job demand–control model, and analysed according to the standard categorization: high strain, active, passive and low strain (reference). Biomarkers (blood pressure, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, coronary artery calcification (CAC) and metabolic syndrome) were measured, or derived through measurements, from clinical examinations. Gender-specific prevalence ratios (PRs) and 95% confidence intervals (CIs) were calculated with regression models and adjusted for age, education, smoking, physical activity, general life stress and body mass index (BMI). Results: The analyses included 3882 participants (52.5% women). High strain (high demands–low control) was linked to increased PR for low HDL cholesterol in women, adjusted for all covariates (PR 1.76; 95% CI 1.25–2.48). High strain was also related to moderately increased PR for metabolic syndrome in men, after adjustments for all covariates except BMI (PR 1.25; 95% CI 1.02–1.52). In addition, passive work (low demands–low control) was associated with diastolic hypertension in women (fully adjusted: PR 1.29; 95% CI 1.05–1.59). All relationships between psychosocial factors and LDL cholesterol or CAC (both genders), or hypertension (men), were non-significant. Conclusions: Poor psychosocial job conditions was associated with the presence of low HDL cholesterol and diastolic hypertension in women, and metabolic syndrome in men. These findings contribute to the knowledge of potential pathways between stressful work and coronary heart disease.

Prevalence of metabolic syndrome and its associated factors among Iranian steel workers

Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Elham Heidary ◽  
Seyed Mahmoud Latifi ◽  
Davood Afshari
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Heart Diseases ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Steel Workers ◽  
Chi Square ◽  
Cross Sectional ◽  
Work Related ◽  
Low Hdl

BACKGROUND: Metabolic syndrome (MetS) is composed of a collection of risk factors for heart diseases and diabetes. In recent decades, metabolic syndrome has been identified as one of the important risk factors leading to the development of work-related diseases. OBJECTIVE: Since few studies have been conducted on evaluating the prevalence of MetS among Iranian workers, this cross-sectional study aimed at assessing the prevalence of MetS and the factors affecting it among Iranian steel workers. METHODS: This study was carried out on 510 employees working in a large steel producing company. The data pertaining to blood pressure, triglycerides, cholesterol, glucose, and demographic information were collected and the Adult Treatment Panel (ATP III) criteria were implemented to diagnose MetS. RESULTS: The prevalence of Mets was obtained equal to 13% and a significant positive relationship was observed between age and the prevalence of metabolic syndrome. From among MetS elements, low HDL cholesterol and increased waist circumference were recognized as the most and the least frequently involved elements with 39.3% and 6.5% prevalence, respectively. Chi-square test was run and the results showed that the prevalence of MetS and some of its components rose at higher BMI values. It was also indicated that MetS and its components had no significant relationship with shift work. CONCLUSION: The current findings revealed that the prevalence of MetS increased with aging. Low HDL and high triglycerides levels were among the main risk factors for MetS. Therefore, considering these risk factors, it should be attempted to develop relevant strategies at workplace to encourage workers to go for a healthier lifestyle so that they can prevent the incidence of MetS.

scholarly journals HUBUNGAN PERILAKU SEDENTARI DENGAN SINDROM METABOLIK PADA PEKERJA

2019 ◽  
Vol 13 (2) ◽  
pp. 145
Author(s):  
Lailiyah Yusna Yusfita
Keyword(s):  
Metabolic Syndrome ◽  
Metabolic Diseases ◽  
Sedentary Lifestyle ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Chi Square Analysis

Sedentary lifestyle has been done by many workers either in the workplace, home, even on transportation. High sedentary lifestyle is a risk factor for metabolic syndrome among workers that cause of metabolic diseases such as Coronary Heart Disease, diabetes mellitus type 2, and Stroke. According to the International Diabetes Federation (IDF) in 2005, the metabolic syndrome is characterized by abdominal obesity plus at least 2 other positive components consisting of hypertriglycerides, low HDL cholesterol, hypertension, and hyperglycemia. This study is a cross sectional study to determine relationship of sedentary lifestyle with metabolic syndrome. 66 workers of 113 workers who performed Medical Check Up (MCU) at Prima Medika Laboratory Surabaya during November - December 2017 became a sample of this study. Sampling method was simple random sampling. The independent variables in this study were age, sex, and sedentary lifestyle. The dependent variable was metabolic syndrome. This study used Chi-square analysis to assess the relationship between independent variable and dependent variable. The results showed the prevalence of metabolic syndrome among workers was 43.9%. Of the 29 workers with metabolic syndrome, 26 workers had a sedentary lifestyle ≥ 6 hours per day with a median was 9.11 hours per day. There was a correlation between sedentary lifestyle ≥ 6 hours per day with metabolic syndrome (p = 0.000), whereas showed no association with metabolic syndrome between age (p = 0.058) and sex (p = 0.168). The conclusions of this study were sedentary ≥ 6 hours per day associated with metabolic syndrome among workers. Workers should reduce sedentary lifestyle by stretching, avoiding sitting too long while working, and increasing physical activity in the workplace.

scholarly journals Peripheral polyneuropathy in severely obese patients with metabolic syndrome but without diabetes: Association with low HDL-cholesterol

2017 ◽  
Vol 63 (4) ◽  
pp. 324-331 ◽  
Author(s):  
Otto Henrique Nienov ◽  
Luciana Matte ◽  
Lisiane Stefani Dias ◽  
Helena Schmid
Keyword(s):  
Metabolic Syndrome ◽  
Univariate Analysis ◽  
Hdl Cholesterol ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Serum Triglycerides ◽  
Cross Sectional ◽  
Peripheral Polyneuropathy ◽  
Low Hdl ◽  
Severely Obese

Summary Introduction: The purpose of this study was to evaluate the prevalence of peripheral polyneuropathy (PPN) in subjects with grade II and III obesity (Ob-II,III) and metabolic syndrome (MetS) but without diabetes and to investigate possible associated factors. Method: A cross-sectional study was performed in non-diabetic Ob-II,III,MetS patients using the Michigan Neuropathy Screening Instrument (MNSI) to assess the presence of PPN. Results: A total of 24 of 218 non-diabetic Ob-II,III,MetS patients had PPN. Based on univariate analysis, serum levels of LDL-cholesterol (p=0.046) were significantly associated with PPN, while serum triglycerides (p=0.118) and low HDL-cholesterol (p=0.057) showed a tendency toward this association. On a Poisson regression analysis, when the three possible associations were included, low HDL-cholesterol (p=0.047) remained independently associated. Conclusion: In non-diabetic Ob-II,III,MetS patients, PPN defined by the MNSI showed a high prevalence and was associated with low levels of HDL-cholesterol. In order to diagnose that complication, neurological evaluation should be performed in these patients.

Metabolic Syndrome among Young Business Process Outsourcing Industry Employees

2016 ◽  
Vol 53 (3) ◽  
pp. 286
Author(s):  
Ravinder Chadha ◽  
Renuka Pathak ◽  
Ishu Kataria
Keyword(s):  
Metabolic Syndrome ◽  
Business Process ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
National Capital Region ◽  
Business Process Outsourcing ◽  
Cross Sectional ◽  
High Waist Circumference ◽  
National Capital

Metabolic Syndrome (MetS) is a complicated disorder that increases a person's risk to cardiovascular disease and diabetes mellitus and therefore, needs to be diagnosed early. Young adults in business process outsourcing industry (BPO) may be more susceptible to the syndrome owing to the sedentary nature of their work and other lifestyle factors. This study aimed at assessing the prevalence of MetS among young business process outsourcing industry employees (21-30 years). In this cross-sectional study conducted in the National Capital Region of India, MetS was diagnosed using the Adult Treatment Pattern III (NCEP ATPIII, 2001) and International Diabetes Federation (IDF, 2005) (ethnicity specific) criteria among 415 business process outsourcing employees (274 males; 141 females) working at the calling level. Prevalence of MetS was 11.8% according to ATPIII criteria (14.6% males; 6.4% females) and 18.3% according to IDF criteria (22.3% males; 10.6% females) and was significantly higher in males compared to females (ATPIII p = 0.014; 95% CI 0.02, 0.14; IDF:p = 0.004; 95% CI 0.05, 0.19). As per the ATPIII criteria, highest proportion of the employees had low levels of HDL cholesterol (48.2%) whereas as per the IDF criteria, they had high waist circumference (58.6%). MetS was significantly associated with being single (ATPIII p=0.003; IDF p=0.012), having monthly income more than 20,000 INR (ATPIII p=0.009), having waist to height ratio ≥ 0.5 (ATPIII p=0.002; IDF p=0.000) and BMI ≥ 23kg/m<sup>2</sup> (ATPIII p=0.000; IDF p=0.000). With nearly 1/5th of the BPO employees having MetS at a young age (21-30 years), there is an urgent need to initiate appropriate workplace screening and intervention strategies to prevent and reverse the syndrome among them.

scholarly journals SLEEP DURATION AND METABOLIC SYNDROME IN OBESE ADOLESCENTS

2021 ◽  
Vol 16 (1) ◽  
pp. 33
Author(s):  
Nur Aisiyah Widjaja ◽  
Rendi Aji Prihaningtyas ◽  
Roedi Irawan ◽  
Meta Herdiana Hanindita
Keyword(s):  
Metabolic Syndrome ◽  
Sleep Duration ◽  
Fasting Blood Glucose ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Obese Adolescents ◽  
Glucose Levels

Shorter sleep duration is a risk factor for obesity and metabolic syndrome. Previous studies conducted on diff erent races showed inconsistent results. The purpose of this study was to analyze the diff erences in sleep duration in obese adolescents who suff er from metabolic syndrome compared with obese adolescents who do not suff er from metabolic syndrome. A cross sectional study was carried out on 59 obese adolescents who visited the Pediatric Nutrition and Metabolic Disease Clinic in Dr. Soetomo General Academic Hospital, Surabaya. Subjects were selected using total sampling techniques who met the inclusion and exclusion criteria in August-November 2018. Anthropometry (weight, height and waist circumference), blood pressure, and blood tests (HDL cholesterol levels, triglycerides, and fasting blood glucose levels) were held to determine obesity according to CDC 2000 and metabolic syndrome according to International Diabetes Federation. The diff erence in sleep duration in obese adolescents suff ering from metabolic syndrome and without metabolic syndrome analyzed using Chi square test. A total of 27 subjects (45.8%) suff ered from metabolic syndrome. Most obese adolescents (57,6%) have suffi cient sleep duration (≥ 8 hours/day). There was no sleep duration diff erences in obese adolescents suff ering and not suff ering from metabolic syndrome (p> 0.05).

scholarly journals Gender Differentials of Metabolic Syndrome in Bangladesh taking Menopause into Consideration

2020 ◽  
Vol 5 (1) ◽  
pp. 101
Author(s):  
Syed Muhammad Baqui Billah ◽  
Muna Shalima Jahan ◽  
Saadi Al Jundi ◽  
Ahmad Mamoun Rajab
Keyword(s):  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Premenopausal Women ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Policy Makers ◽  
Gender Differentials ◽  
Menopausal Women ◽  
Low Hdl ◽  
Study Population

Objective:To assess the gender differences of metabolic syndrome (MetS) in Bangladesh and factors associated with it.Materials and methods: Cross sectional study was performed on 227 premenopausal women, 48 menopausal women and 217 men. The gender differentials were studied with measurement of waist circumference, blood pressure and fasting blood for triglyceride (TG), high density lipoprotein (HDL), blood sugar (FBS).Results:Premenopausal women had 22.9% (95% CI: 17.9-28.8%), menopausal women had 43.8% (95% CI: 30.7-57.7%), and the men had 53.9% (95% CI: 47.3-60.4%) prevalence of MetS giving a 1:1.7:2.1 ratio of premenopausal, menopausal women and men prevalence respectively. More than 95% of study population had low HDL irrespective of gender and menopause status. Obesity was 5.3% in premenopausal women, 14.6% in menopausal women and 54.4% in men. HTN was 10.6% in premenopausal women, 35.4% in menopausal women, and 19.4% in men. High TG was 42.5% in premenopausal women, 41.7%, in menopausal women and 62.0% in men. High FBS was 22.0% in premenopausal women, 37.5% in menopausal women and 30.4% in men.Conclusion: Compared to premenopausal women, MetS in men was two times higher and nearly two times higher in menopausal women, pulling menopausal women prevalence almost equal to men. Menopausal women had high prevalence of HTN while obesity was more prevalent in men. Dyslipidemia should be a concern for the policy makers in search of a prevention program.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 101-107

scholarly journals The prevalence of the metabolic syndrome increases through the quartiles of thyroid stimulating hormone in a population-based sample of euthyroid subjects

2014 ◽  
Vol 58 (9) ◽  
pp. 926-932 ◽  
Author(s):  
Alexander Shinkov ◽  
Anna-Maria Borissova ◽  
Roussanka Kovatcheva ◽  
Iliana Atanassova ◽  
Jordan Vlahov ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Hdl Cholesterol ◽  
Population Based ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Low Hdl ◽  
C 32 ◽  
Serum Tsh

Objective The aim of the study was to assess the prevalence and characteristics of metabolic syndrome (MetS) and its elements in relation to TSH in euthyroid subjects. Materials and methods In the cross-sectional study, 2,153 euthyroid adults, 47.2 ± 14.5 years (20-94) with no current antithyroid or thyroid replacement therapy were enrolled. All participants filled a questionnaire on past and current morbidities, medication and smoking. Body weight, height, waist circumference, serum TSH, glucose and lipids were measured. The subjects were stratified by quartiles of TSH (QTSH) and the prevalence of the MetS elements was calculated. MetS was determined by the IDF 2005 criteria. Results Overweight prevalence was 37.2% (35.2-39.2), obesity in 25.1% (23.3-26.9), abdominal obesity – 61.4% (59.3-63.5), hypertension – 42.1% (38.9-43.1), diabetes/increased fasting glucose – 13.6% (12.1-15), low HDL-cholesterol – 27.6% (25.7-29.5), hypertriglyceridemia – 24.1% (22.3-25.9), MetS – 32.2% (30.2-34.2). MetS was more prevalent in the highest QTSH (34.9%, 30.9-38.9) than the lowest (27%, 23.3-30.9), p < 0.001, as were low HDL-C (32%, 28-35.9 vs. 25%, 21.3-28.7, p < 0.001) and hypertriglyceridemia (26.8%, 23-30.5 vs. 20.4%, 17-23.8, p = 0.015). Each QTSH increased the risk of MetS by 14%, p < 0.001, of hypertriglyceridemia by 20%, p = 0.001 and of low LDL-C by 9%, p = 0.042. Other significant factors for MetS were age, male gender and obesity. Conclusion The prevalence of MetS increased with higher QTSH within the euthyroid range, mostly by an increase in the dyslipidemia. Arq Bras Endocrinol Metab. 2014;58(9):926-32

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