Prevalence of metabolic syndrome and its associated factors among Iranian steel workers

Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Elham Heidary ◽  
Seyed Mahmoud Latifi ◽  
Davood Afshari

BACKGROUND: Metabolic syndrome (MetS) is composed of a collection of risk factors for heart diseases and diabetes. In recent decades, metabolic syndrome has been identified as one of the important risk factors leading to the development of work-related diseases. OBJECTIVE: Since few studies have been conducted on evaluating the prevalence of MetS among Iranian workers, this cross-sectional study aimed at assessing the prevalence of MetS and the factors affecting it among Iranian steel workers. METHODS: This study was carried out on 510 employees working in a large steel producing company. The data pertaining to blood pressure, triglycerides, cholesterol, glucose, and demographic information were collected and the Adult Treatment Panel (ATP III) criteria were implemented to diagnose MetS. RESULTS: The prevalence of Mets was obtained equal to 13% and a significant positive relationship was observed between age and the prevalence of metabolic syndrome. From among MetS elements, low HDL cholesterol and increased waist circumference were recognized as the most and the least frequently involved elements with 39.3% and 6.5% prevalence, respectively. Chi-square test was run and the results showed that the prevalence of MetS and some of its components rose at higher BMI values. It was also indicated that MetS and its components had no significant relationship with shift work. CONCLUSION: The current findings revealed that the prevalence of MetS increased with aging. Low HDL and high triglycerides levels were among the main risk factors for MetS. Therefore, considering these risk factors, it should be attempted to develop relevant strategies at workplace to encourage workers to go for a healthier lifestyle so that they can prevent the incidence of MetS.

2020 ◽  
Author(s):  
yinxia su ◽  
Wenli Li ◽  
Yaoqin Lu ◽  
Mingyue Xue ◽  
Muyaseer Haireti ◽  
...  

Abstract Background The prevalence of metabolic syndrome (MetS) of comprehensive population are always lower than mono- population. However, studies on MetS and its components of it and its subgroups (different ages, genders, races, regions) based on big data and using a same diagnosis criterion are rare. Method: A total of 9,745,640 Chinese adults aged ≥ 18 years in Xinjiang,the largest autonomous region of Multi-ethnic, were enrolled in the study. MetS was defined by modified Adults Treatment Panel (ATP III) criteria.Prevalence of metabolic syndrome and its components were calculated. To further explore the correlates of MetS and its components logistic regression were used. Results The overall prevalence of MetS was 20.85% [Sex: 20.06% in female, 21.56% in man; Age: 39.22% in 60 year older followed by 40–59 year 26.32% and 18–39 years 9.56%; Ethnicity: 28.19% in Hui followed by Han (26.39%), Uyghur(18.56%), Other(18.61%), Kazak(17.98%), Mongolian (17.87%), Kyrgyz(14.44%)], living in city and town (23.03%) or north(24.78%) had higher prevalence of MetS than living in rural (19.94%) and South (17.66%). Although the prevalence of hypertension, smoking, drinking and lack of physical activity in Kyrgyz, Mongolian and Kazakh were higher than those of other ethnic groups, the risk of MetS was lower than that of other. The results also showed that although their risk of central obesity and hypertension was higher than that of Han, Hui, Uygur and other, the risk of high-TG, low HDL-C and Elevated-FPG was significantly lower than that of other ethnic groups. Among them, the Mongolian had the lowest risk of high-TG and low-HDL-C, while the Kazakh had the lowest risk of elevated-FPG. In addition, except that the risk of central obesity in males was lower than that in females, the other components of males were higher than those in females, but the risk of MetS was lower than that in females. The risk of MetS and its components in the elderly was significantly higher than that in the young, and physical activity did not show reduce the risk of MetS in the general population. Conclusion The reason why the prevalence of MetS in the comprehensive population is lower than that in most mono-population may be that some subgroups of the population have the ability to resist risk factors in terms of genetic structure such as Kyrgyz, Mongolian, Kazak, and the influence in this aspect may exceed that of lifestyle. Within each subgroup, the prevalence of MetS is still increasing. Central obesity is an important risk factor for women with MetS. Elevated-FPG and high-TG are the most important risk factors of MetS in Han, Hui. Climate and lifestyle are the main causes of MetS in northern Xinjiang and city and town residents.


2017 ◽  
pp. 481-487 ◽  
Author(s):  
L. CIBIČKOVÁ ◽  
K. LANGOVÁ ◽  
H. VAVERKOVÁ ◽  
V. KUBÍČKOVÁ ◽  
D. KARÁSEK

Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype. We found that levels of uric acid are associated with parameters of metabolic syndrome. Specifically, dyslipidemia characteristic for metabolic syndrome (low HDL cholesterol and high triglycerides) correlates better with uric acid levels than parameters of insulin resistance. Also waist circumference correlates better with uric acid levels than body mass index. Patients with hypertriglyceridemic waist phenotype had higher levels of uric acid when compared with patients without this phenotype. Serum uric acid levels are even in low levels linearly correlated with parameters of metabolic syndrome (better with typical lipid characteristics than with parameters of insulin resistance) and could be associated with higher cardiovascular risk.


2022 ◽  
pp. 140349482110640
Author(s):  
Mia Söderberg ◽  
Helena Eriksson ◽  
Kjell Torén ◽  
Göran Bergström ◽  
Eva Andersson ◽  
...  

Aims: The aim of this study was to investigate associations between psychosocial work exposure and the presence of biological and imaging biomarkers of cardiovascular disease. Methods: This cross-sectional study was conducted in a sub-cohort of the Swedish CArdioPulmonary bioImage Study (SCAPIS). Psychosocial exposure was evaluated with the job demand–control model, and analysed according to the standard categorization: high strain, active, passive and low strain (reference). Biomarkers (blood pressure, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, coronary artery calcification (CAC) and metabolic syndrome) were measured, or derived through measurements, from clinical examinations. Gender-specific prevalence ratios (PRs) and 95% confidence intervals (CIs) were calculated with regression models and adjusted for age, education, smoking, physical activity, general life stress and body mass index (BMI). Results: The analyses included 3882 participants (52.5% women). High strain (high demands–low control) was linked to increased PR for low HDL cholesterol in women, adjusted for all covariates (PR 1.76; 95% CI 1.25–2.48). High strain was also related to moderately increased PR for metabolic syndrome in men, after adjustments for all covariates except BMI (PR 1.25; 95% CI 1.02–1.52). In addition, passive work (low demands–low control) was associated with diastolic hypertension in women (fully adjusted: PR 1.29; 95% CI 1.05–1.59). All relationships between psychosocial factors and LDL cholesterol or CAC (both genders), or hypertension (men), were non-significant. Conclusions: Poor psychosocial job conditions was associated with the presence of low HDL cholesterol and diastolic hypertension in women, and metabolic syndrome in men. These findings contribute to the knowledge of potential pathways between stressful work and coronary heart disease.


2011 ◽  
Vol 12 (4) ◽  
pp. 531-538 ◽  
Author(s):  
Szilvia Fiatal ◽  
Endre Szigethy ◽  
György Széles ◽  
Réka Tóth ◽  
Róza Ádány

The aim of our study was to evaluate whether any association exists between metabolic syndrome (MS) and ACE I/D and AGT M235T gene polymorphisms in Hungarians as an example of European Caucasian population. Study subjects of our cross-sectional study were recruited from the Hungarian General Practitioners’ Morbidity Sentinel Stations Program. The study population ( n = 1762) approximates very well the age and sex distribution of the general Hungarian population. MS was defined according to the latest diagnostic criteria proposed by the International Diabetes Federation. The frequency of DD genotype (31.36% vs. 25.42%, p = 0.006) and the frequency of D allele (0.56 vs. 0.51, p = 0.006) were significantly higher in the metabolic group than in the non-metabolic group. The distribution of the AGT M235T polymorphism was similar in each group investigated. Association was shown in the case of patients in whom central obesity was combined with elevated TG and low HDL cholesterol level ( p = 0.024 and p = 0.022). It suggests that ACE I/D polymorphism is likely to be involved in lipid metabolism.


2017 ◽  
Vol 63 (4) ◽  
pp. 324-331 ◽  
Author(s):  
Otto Henrique Nienov ◽  
Luciana Matte ◽  
Lisiane Stefani Dias ◽  
Helena Schmid

Summary Introduction: The purpose of this study was to evaluate the prevalence of peripheral polyneuropathy (PPN) in subjects with grade II and III obesity (Ob-II,III) and metabolic syndrome (MetS) but without diabetes and to investigate possible associated factors. Method: A cross-sectional study was performed in non-diabetic Ob-II,III,MetS patients using the Michigan Neuropathy Screening Instrument (MNSI) to assess the presence of PPN. Results: A total of 24 of 218 non-diabetic Ob-II,III,MetS patients had PPN. Based on univariate analysis, serum levels of LDL-cholesterol (p=0.046) were significantly associated with PPN, while serum triglycerides (p=0.118) and low HDL-cholesterol (p=0.057) showed a tendency toward this association. On a Poisson regression analysis, when the three possible associations were included, low HDL-cholesterol (p=0.047) remained independently associated. Conclusion: In non-diabetic Ob-II,III,MetS patients, PPN defined by the MNSI showed a high prevalence and was associated with low levels of HDL-cholesterol. In order to diagnose that complication, neurological evaluation should be performed in these patients.


Author(s):  
Xinlei Chen ◽  
Shuliang Deng ◽  
Cecilia Sena ◽  
Chuhan Zhou ◽  
Vidhu V Thaker

Abstract Context Thyroid hormones play an important role in the metabolic homeostasis and higher levels have been associated with cardiometabolic risk. Objective To examine the association of cardiometabolic risk factors with TSH levels in US youth. Design & Setting Cross-sectional study of youth aged 12-18 years without known thyroid abnormalities from five National Health and Nutrition Examination Survey cycles (n=2,818) representing 15.4 million US children. Subclinical hypothyroidism (SH) was defined as TSH levels 4.5-10 mIU/L. Assessed cardiometabolic risk factors include abdominal obesity (waist circumference > 90 th percentile), hypertriglyceridemia (TG ≥130 mg/dL), low HDL cholesterol (HDL-C < 40 mg/dL), elevated blood pressure (SBP and DBP ≥90 th percentile), hyperglycemia (FBG ≥100 mg/dL, or known diabetes), insulin resistance (HOMA-IR > 3.16) and elevated alanine transferase (ALT ≥ 50 U/L for boys and ≥ 44 U/L for girls). Age and sex- specific percentiles for thyroid parameters were calculated. Results In this cohort of youth (51.3% male), 31.2% had overweight/obesity. The prevalence of SH was 2.0 % (95% CI 1.2-3.1). The median TSH levels were higher in youth with overweight/obesity (p<.001). Adjusting for age, sex, race/ethnicity and obesity, youth with TSH in the 4 th quantile had higher odds of abdominal obesity (OR 2.53 [1.43-4.46], p = .002), insulin resistance (OR 2.82 [1.42-5.57], p=.003) and ≥ 2 CMRF (OR 2.20 [1.23-3.95], p=.009). Conclusions The prevalence of SH is low in US youth. The higher odds of insulin resistance and cardiometabolic risk factors in youth with TSH levels > 75 th percentile requires further study.


2021 ◽  
Vol 16 (1) ◽  
pp. 33
Author(s):  
Nur Aisiyah Widjaja ◽  
Rendi Aji Prihaningtyas ◽  
Roedi Irawan ◽  
Meta Herdiana Hanindita

Shorter sleep duration is a risk factor for obesity and metabolic syndrome. Previous studies conducted on diff erent races showed inconsistent results. The purpose of this study was to analyze the diff erences in sleep duration in obese adolescents who suff er from metabolic syndrome compared with obese adolescents who do not suff er from metabolic syndrome. A cross sectional study was carried out on 59 obese adolescents who visited the Pediatric Nutrition and Metabolic Disease Clinic in Dr. Soetomo General Academic Hospital, Surabaya. Subjects were selected using total sampling techniques who met the inclusion and exclusion criteria in August-November 2018. Anthropometry (weight, height and waist circumference), blood pressure, and blood tests (HDL cholesterol levels, triglycerides, and fasting blood glucose levels) were held to determine obesity according to CDC 2000 and metabolic syndrome according to International Diabetes Federation. The diff erence in sleep duration in obese adolescents suff ering from metabolic syndrome and without metabolic syndrome analyzed using Chi square test. A total of 27 subjects (45.8%) suff ered from metabolic syndrome. Most obese adolescents (57,6%) have suffi cient sleep duration (≥ 8 hours/day). There was no sleep duration diff erences in obese adolescents suff ering and not suff ering from metabolic syndrome (p> 0.05).


2019 ◽  
Vol 04 (01) ◽  
pp. 001-007
Author(s):  
Sudha Bala ◽  
Madhuri Taranikanti ◽  
Aruna Kumari Yerra ◽  
Bhavya Gundepudi

Abstract Background and Aim Cardiovascular diseases among women are rapidly increasing as an epidemic. Identification of risk factors is very essential along with its clinical application to avoid misdiagnosis and poor management. This study aims to assess various risk factors among women who are industrial residents of Hyderabad, to estimate the risk by using Framingham risk score (FRS) categorization. Methods A community-based cross-sectional study was undertaken among 370 women using World Health Organization (WHO) stepwise approach (STEPS) questionnaire schedule with gender-specific risk factors such as metabolic syndrome, menopause, and pregnancy-associated complications; anthropometry, blood pressure, and lipid profile measurements. Risk estimate of over 10 years has been estimated with FRS. ANOVA (analysis of variance), and chi-square test was used to depict association of risk with various variables. Results Our study determined 3.7% at intermediate risk and 2.5% at higher risk using FRS. Highest prevalence of risk factors included mainly poor intake of good-cholesterol diet among 96%, predicted by low high-density lipoprotein (HDL) among 89%, poor intake of fruits among 81%, higher waist circumference (> 80 cm) among 66.7%, raised blood glucose among 58.4%, obesity (47.2%), extra intake of salt (40%), and metabolic syndrome among 29.7% with predominance in younger age group. Conclusion Estimation of cardiovascular risk at an earlier stage provides an opportunity to target young women among whom the metabolic syndrome is the major determinant with preventive strategies.


2014 ◽  
Vol 58 (9) ◽  
pp. 926-932 ◽  
Author(s):  
Alexander Shinkov ◽  
Anna-Maria Borissova ◽  
Roussanka Kovatcheva ◽  
Iliana Atanassova ◽  
Jordan Vlahov ◽  
...  

Objective The aim of the study was to assess the prevalence and characteristics of metabolic syndrome (MetS) and its elements in relation to TSH in euthyroid subjects. Materials and methods In the cross-sectional study, 2,153 euthyroid adults, 47.2 ± 14.5 years (20-94) with no current antithyroid or thyroid replacement therapy were enrolled. All participants filled a questionnaire on past and current morbidities, medication and smoking. Body weight, height, waist circumference, serum TSH, glucose and lipids were measured. The subjects were stratified by quartiles of TSH (QTSH) and the prevalence of the MetS elements was calculated. MetS was determined by the IDF 2005 criteria. Results Overweight prevalence was 37.2% (35.2-39.2), obesity in 25.1% (23.3-26.9), abdominal obesity – 61.4% (59.3-63.5), hypertension – 42.1% (38.9-43.1), diabetes/increased fasting glucose – 13.6% (12.1-15), low HDL-cholesterol – 27.6% (25.7-29.5), hypertriglyceridemia – 24.1% (22.3-25.9), MetS – 32.2% (30.2-34.2). MetS was more prevalent in the highest QTSH (34.9%, 30.9-38.9) than the lowest (27%, 23.3-30.9), p < 0.001, as were low HDL-C (32%, 28-35.9 vs. 25%, 21.3-28.7, p < 0.001) and hypertriglyceridemia (26.8%, 23-30.5 vs. 20.4%, 17-23.8, p = 0.015). Each QTSH increased the risk of MetS by 14%, p < 0.001, of hypertriglyceridemia by 20%, p = 0.001 and of low LDL-C by 9%, p = 0.042. Other significant factors for MetS were age, male gender and obesity. Conclusion The prevalence of MetS increased with higher QTSH within the euthyroid range, mostly by an increase in the dyslipidemia. Arq Bras Endocrinol Metab. 2014;58(9):926-32


2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Suchi Ilmi Herman ◽  
Muhammad Syukri ◽  
Efrida Efrida

AbstrakSumatera Barat merupakan provinsi dengan prevalensi penyakit jantung tertinggi ke-4 di Indonesia. Prevalensi penyakit ini meningkat disebabkan karena faktor risiko yang dapat dimodifikasi yaitu dislipidemia, hipertensi, diabetes melitus, merokok, dan obesitas. Faktor risiko tersebut terkait dengan peningkatan kejadian PJK. Tujuan penelitian ini adalah untuk mengetahui hubungan faktor risiko yang dapat dimodifikasi dengan kejadian PJK. Penelitian ini merupakan penelitian analitik dengan desain potong lintang yang dilakukan di RS Dr. M. Djamil Padang dari Desember 2012 sampai Mei 2013. Populasi penelitian ini adalah seluruh pasien PJK yang dirawat inap dan telah dilakukan angiografi pada Januari 2012 sampai Desember 2012 dengan 68 orang sebagai subjek penelitian. Data pasien didapatkan dari rekam medik. Data dideskripsikan dengan tabel dan dianalisis dengan uji chi-square. Hasil penelitian menunjukkan distribusi frekuensi terbanyak pasien PJK terdapat pada kadar kolesterol HDL rendah (64,6%) dan hipertensi (72,5%), namun hasil uji bivariat tidak menunjukkan hubungan yang bermakna antara kadar kolesterol HDL rendah dan hipertensi terhadap kejadian PJK. Kesimpulan hasil penelitian ini ialah kadar kolesterol HDL rendah dan hipertensi belum tentu menyebabkan PJK.Kata kunci: penyakit jantung koroner, faktor risiko, HDLAbstractWest Sumatra is a province with the highest prevalence of heart disease 4th in Indonesia. The prevalence of this disease increases due to modifiable risk factors, namely dyslipidemia, hypertension, diabetes mellitus, smoking, and obesity. The risk factors associate with an increased incidence of Coronary Heart Disease (CHD). The objective of this study was to determine the relationship of modifiable risk factors with CHD events. This study was a cross-sectional analytic design conducted at Hospital Dr. M. Djamil Padang from December 2012 until May 2013. The population in this study were all hospitalized CHD patients and angiography was performed in January 2012 - December 2012 with 68 patients as a research subject. Obtained from the patient's medical record. The data described in tables and analyzed with the chi-squared test. The result showed that the frequency distribution of most CHD patients are at low levels of HDL cholesterol (64.6%) and hypertension (72.5%). Bivariate test results showed no significant association between low HDL cholesterol and hypertension on the incidence of CHD. The conclusion is the low HDL cholesterol levels and hypertension not necessarily lead to CHD.Keywords: coronary heart disease, risk factors, HDL


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