Depression and anxiety symptoms as predictors of mortality in PCI patients at 10 years of follow-up

Several kinds of marital conflict might be solved through constructive communication, development of interaction skills, and behavioral and thought modification. The aim of this study was to show results of the application of a protocol based on cognitive behavioral couple therapy (CBCT) on dyadic adjustment, marital social skills, depression, and anxiety symptoms. The sample consisted of 32 participants (16 couples) divided in two groups by length of marriage: Group 1 (1–7 years) and Group 2 (8–12 years). All subjects recruited were older than 18 and reported having communication problems in their relationship. The ages were M = 30.4, SD = 4.13. The measures were Dyadic Adjustment Scale (DAS), Beck Depression Inventory–II (BDI-II), Beck Anxiety Inventory (BAI), Marital Social Skills Inventory (Inventário de Habilidades Sociais Conjugais [IHSC]), and the Sociodemographic Questionnaire. Participants were assessed pre- and postintervention and had a 6-month follow-up. The intervention consisted of twelve 50-min sessions per couple. Based on three time analyses, both groups obtained the following results: DAS ( p = .001), BDI-II ( p = .000), BAI ( p = .000), and IHSC ( p = .001). We conclude that the CBCT protocol developed for this study, resulted in statistically significant improvements in the couple’s relationship for all variables studied in both groups.

Download Full-text

Sleep symptoms and long-term outcome in adolescents with major depressive disorder: a naturalistic follow-up study

European Child & Adolescent Psychiatry ◽

10.1007/s00787-019-01436-z ◽

2019 ◽

Vol 29 (5) ◽

pp. 595-603 ◽

Cited By ~ 1

Author(s):

Anna S. Urrila ◽

◽

Olli Kiviruusu ◽

Henna Haravuori ◽

Linnea Karlsson ◽

...

Keyword(s):

Major Depressive Disorder ◽

Young Adulthood ◽

Psychosocial Functioning ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Major Depressive ◽

Term Outcome ◽

Long Term Outcome

Abstract Sleep abnormalities in major depressive disorder (MDD) have been suggested to represent a vulnerability trait, which might predispose the individual to long-term psychiatric morbidity. In this study, we sought to assess whether the presence of sleep symptoms among adolescents with MDD is associated with poorer long-term outcome in young adulthood during naturalistic follow-up. Adolescent outpatients diagnosed with MDD (n = 166; age 13–19 years, 17.5% boys) were followed up during 8 years in naturalistic settings. N = 112 adolescents (16.1% boys) completed the 8-year assessment. Sleep symptoms and psychosocial functioning were assessed with structured clinical interviews, and depressive and anxiety symptoms with questionnaires. The severity of sleep symptoms at baseline was not associated with worse outcome at 8 years in terms of any of the outcome measures tested. In particular, the presence of a disturbed sleep–wake rhythm at baseline was associated with a more favourable outcome at 8 years: less depression and anxiety symptoms and higher level of psychosocial functioning. The presence of sleep symptoms in young adulthood was associated with the presence of current depression and anxiety symptoms and poorer psychosocial functioning. The presence of sleep symptoms at follow-up seems to be state-dependent: they are observed in conjunction with other psychiatric symptoms. Contrary to our hypothesis, our results suggest that sleep complaints among adolescents with MDD do not lead to poorer long-term clinical outcome in young adulthood. The link between sleep–wake rhythm disturbance and better long-term outcome needs to be confirmed and examined in detail in further studies, but here we speculate about possible explanations.

Download Full-text

423 A LONG TERM FOLLOW UP OF PAIN, DEPRESSION AND ANXIETY SYMPTOMS AMONG FIBROMYALGIA PATIENTS

European Journal of Pain ◽

10.1016/s1090-3801(06)60426-6 ◽

2006 ◽

Vol 10 (S1) ◽

pp. S113a-S113

Author(s):

E.A. Fors ◽

T. Landmark ◽

P.C. Borchgrevink

Keyword(s):

Anxiety Symptoms ◽

Depression And Anxiety ◽

Long Term Follow Up

Download Full-text

Thyroid dysfunction in patients of depression and anxiety and response to therapy

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20213921 ◽

2021 ◽

Vol 9 (10) ◽

pp. 2994

Author(s):

Harsha . ◽

Amandeep . ◽

Jitendra Jeenger ◽

R.S Ahlawat ◽

Manju Subberwal

Keyword(s):

Anxiety Disorder ◽

Clinical Diagnosis ◽

Thyroid Dysfunction ◽

Anxiety Symptoms ◽

Entry Point ◽

Control Group ◽

Depression And Anxiety ◽

Thyroid Profile ◽

Experimental Group

Background: Depression and anxiety are the most common psychiatric presentation in thyroid dysfunction. Aim of the study was to determine the thyroid profile in patients with depressive and anxiety symptoms and to determine the change in symptoms with correction of thyroid profile.Methods: This longitudinal observational study was conducted in patients presented with depressive or anxiety symptoms who visited the psychiatry out patient department (OPD) first time. Two groups were made based on the serum thyroid profile. First group, (n=27) was patients with depression and anxiety with hypothyroidism (experimental group) and second was (n=123) without hypothyroidism (control group). Experimental group, (n=27) was then exposed to thyroxine, 15 patients came for first follow up and 11 patients came for second follow up.Results: The 63% of patients in the experimental group and 62.6% of patients in the control group were of female gender, 66.7% and 33.3% of patients in the experimental group had depressive disorder and anxiety disorder respectively. TSH level of 11 patients of experimental group had significantly less value in first follow up compared to entry point (p=0.002). Generalized anxiety disorder (GAD) 7 scores were significantly lower in first and second follow up than that of the entry point in 11 patients of experimental group (p=0.008, 0.016 respectively).Conclusions: Many patients of the clinical diagnosis of depression (17.6%) and clinical diagnosis of anxiety (18.75%) had hypothyroidism during the first visit to the psychiatry OPD. There was significant reduction in the hypothyroid patients of the serum thyroid stimulating hormone (TSH) value and anxiety scores during the follow up after treatment with levothyroxine.

Download Full-text

Mindfulness Training Improves Quality of Life and Reduces Depression and Anxiety Symptoms Among Police Officers: Results From the POLICE Study—A Multicenter Randomized Controlled Trial

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.624876 ◽

2021 ◽

Vol 12 ◽

Author(s):

Marcelo Trombka ◽

Marcelo Demarzo ◽

Daniel Campos ◽

Sonia B. Antonio ◽

Karen Cicuto ◽

...

Keyword(s):

Police Officers ◽

Controlled Trial ◽

High Stress ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Post Intervention ◽

Self Compassion ◽

Multicenter Randomized Controlled Trial

Background: Police officers' high-stress levels and its deleterious consequences are raising awareness to an epidemic of mental health problems and quality of life (QoL) impairment. There is a growing evidence that mindfulness-based interventions are efficacious to promote mental health and well-being among high-stress occupations.Methods: The POLICE study is a multicenter randomized controlled trial (RCT) with three assessment points (baseline, post-intervention, and 6-month follow-up) where police officers were randomized to mindfulness-based health promotion (MBHP) (n = 88) or a waiting list (n = 82). This article focuses on QoL, depression and anxiety symptoms, and religiosity outcomes. Mechanisms of change and MBHP feasibility were evaluated.Results: Significant group × time interaction was found for QoL, depression and anxiety symptoms, and non-organizational religiosity. Between-group analysis showed that MBHP group exhibited greater improvements in QoL, and depression and anxiety symptoms at both post-intervention (QoL d = 0.69 to 1.01; depression d = 0.97; anxiety d = 0.73) and 6-month follow-up (QoL d = 0.41 to 0.74; depression d = 0.60; anxiety d = 0.51), in addition to increasing non-organizational religiosity at post-intervention (d = 0.31). Changes on self-compassion mediated the relationship between group and pre-to-post changes for all QoL domains and facets. Group effect on QoL overall health facet at post-intervention was moderated by mindfulness trait and spirituality changes.Conclusion: MBHP is feasible and efficacious to improve QoL, and depression and anxiety symptoms among Brazilian officers. Results were maintained after 6 months. MBHP increased non-organizational religiosity, although the effect was not sustained 6 months later. To our knowledge, this is the first mindfulness-based intervention RCT to empirically demonstrate these effects among police officers. Self-compassion, mindfulness trait, and spirituality mechanisms of change are examined.Clinical Trial Registration:www.ClinicalTrials.gov. identifier: NCT03114605.

Download Full-text

EMDR for Survivors of Life-Threatening Cardiac Events: Results of a Pilot Study

Journal of EMDR Practice and Research ◽

10.1891/1933-3196.5.1.2 ◽

2011 ◽

Vol 5 (1) ◽

pp. 2-13 ◽

Cited By ~ 24

Author(s):

Emanuele Arabia ◽

Maria Luisa Manca ◽

Roger M. Solomon

Keyword(s):

Pilot Study ◽

Cardiac Event ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Ptsd Symptoms ◽

Cardiac Events ◽

Life Threatening ◽

Clinically Significant ◽

Better Than

This pilot study evaluated the effectiveness of eye movement desensitization and reprocessing (EMDR) in treating posttraumatic stress disorder (PTSD) symptoms and concomitant depressive and anxiety symptoms in survivors of life-threatening cardiac events. Forty-two patients undergoing cardiac rehabilitation who (a) qualified for the PTSD criterion “A” in relation to a cardiac event and (b) presented clinically significant PTSD symptoms were randomized to a 4-week treatment of EMDR or imaginal exposure (IE). Data were gathered on PTSD, anxiety, and depressive symptoms at pretreatment, posttreatment, and 6-month follow-up. EMDR was effective in reducing PTSD, depressive, and anxiety symptoms and performed significantly better than IE for all variables. These findings provide preliminary support for EMDR as an effective treatment for the symptoms of PTSD, depression, and anxiety that can follow a life-threatening cardiac event.

Download Full-text

Collaborative care for depression and anxiety disorders: results and lessons learned from the Danish cluster-randomized Collabri trials

BMC Family Practice ◽

10.1186/s12875-020-01299-3 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Nadja Kehler Curth ◽

Ursula Ødum Brinck-Claussen ◽

Carsten Hjorthøj ◽

Annette Sofie Davidsen ◽

John Hagel Mikkelsen ◽

...

Keyword(s):

Anxiety Disorder ◽

Collaborative Care ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Treatment As Usual ◽

Symptoms Of Depression ◽

Care Managers ◽

Significant Difference ◽

Cluster Randomized

Abstract Background Meta-analyses suggest that collaborative care (CC) improves symptoms of depression and anxiety. In CC, a care manager collaborates with a general practitioner (GP) to provide evidence-based care. Most CC research is from the US, focusing on depression. As research results may not transfer to other settings, we developed and tested a Danish CC-model (the Collabri-model) for depression, panic disorder, generalized anxiety disorder, and social anxiety disorder in general practice. Methods Four cluster-randomized superiority trials evaluated the effects of CC. The overall aim was to explore if CC significantly improved depression and anxiety symptoms compared to treatment-as-usual at 6-months’ follow-up. The Collabri-model was founded on a multi-professional collaboration between a team of mental-health specialists (psychiatrists and care managers) and GPs. In collaboration with GPs, care managers provided treatment according to a structured plan, including regular reassessments and follow-up. Treatment modalities (cognitive behavioral therapy, psychoeducation, and medication) were offered based on stepped care algorithms. Face-to-face meetings between GPs and care managers took place regularly, and a psychiatrist provided supervision. The control group received treatment-as-usual. Primary outcomes were symptoms of depression (BDI-II) and anxiety (BAI) at 6-months’ follow-up. The incremental cost-effectiveness ratio (ICER) was estimated based on 6-months’ follow-up. Results Despite various attempts to improve inclusion rates, the necessary number of participants was not recruited. Seven hundred thirty-one participants were included: 325 in the depression trial and 406 in the anxiety trials. The Collabri-model was implemented, demonstrating good fidelity to core model elements. In favor of CC, we found a statistically significant difference between depression scores at 6-months’ follow-up in the depression trial. The difference was not significant at 15-months’ follow-up. The anxiety trials were pooled for data analysis due to inadequate sample sizes. At 6- and 15-months’ follow-up, there was a difference in anxiety symptoms favoring CC. These differences were not statistically significant. The ICER was 58,280 Euro per QALY. Conclusions At 6 months, a significant difference between groups was found in the depression trial, but not in the pooled anxiety trial. However, these results should be cautiously interpreted as there is a risk of selection bias and lacking statistical power. Trial registration ClinicalTrials.gov, ID: NCT02678624 and NCT02678845. Retrospectively registered on 7 February 2016.

Download Full-text

Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment

BJPsych Open ◽

10.1192/bjo.2020.68 ◽

2020 ◽

Vol 6 (5) ◽

Cited By ~ 2

Author(s):

Kelly Allott ◽

Caroline Gao ◽

Sarah E. Hetrick ◽

Kate M. Filia ◽

Jana M. Menssink ◽

...

Keyword(s):

Young People ◽

Cognitive Functioning ◽

Negative Impact ◽

Multinomial Logistic Regression ◽

Anxiety Symptoms ◽

Self Report ◽

Depression And Anxiety ◽

Subjective Cognitive Function ◽

The Impact

Background Subjective cognitive difficulties are common in mental illness and have a negative impact on role functioning. Little is understood about subjective cognition and the longitudinal relationship with depression and anxiety symptoms in young people. Aims To examine the relationship between changes in levels of depression and anxiety and changes in subjective cognitive functioning over 3 months in help-seeking youth. Method This was a cohort study of 656 youth aged 12–25 years attending Australian headspace primary mental health services. Subjective changes in cognitive functioning (rated as better, same, worse) reported after 3 months of treatment was assessed using the Neuropsychological Symptom Self-Report. Multivariate multinomial logistic regression analysis was conducted to evaluate the impact of baseline levels of and changes in depression (nine-item Patient Health Questionnaire; PHQ9) and anxiety symptoms (seven-item Generalised Anxiety Disorder scale; GAD7) on changes in subjective cognitive function at follow-up while controlling for covariates. Results With a one-point reduction in PHQ9 at follow-up, there was an estimated 11–18% increase in ratings of better subjective cognitive functioning at follow-up, relative to stable cognitive functioning. A one-point increase in PHQ9 from baseline to follow-up was associated with 7–14% increase in ratings of worse subjective cognitive functioning over 3 months, relative to stable cognitive functioning. A similar attenuated pattern of findings was observed for the GAD7. Conclusions A clear association exists between subjective cognitive functioning outcomes and changes in self-reported severity of affective symptoms in young people over the first 3 months of treatment. Understanding the timing and mechanisms of these associations is needed to tailor treatment.

Download Full-text

Effects of depression and anxiety symptoms on cardiac mortality following myocardial infarction: A 2-year follow-up

International Journal of Psychiatry in Clinical Practice ◽

10.3109/13651501.2010.538065 ◽

2010 ◽

Vol 15 (2) ◽

pp. 91-96 ◽

Cited By ~ 12

Author(s):

Seyed Hamzeh Hosseini ◽

Keyvan Yousefnejad ◽

Sasan Tabiban ◽

Vida Nesarhoseyni ◽

Babak Bagheri ◽

...

Keyword(s):

Myocardial Infarction ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Cardiac Mortality

Download Full-text

Body Dissatisfaction and Mental Health Outcomes of Youth on Gender-Affirming Hormone Therapy

10.1542/9781610025423-body ◽

2021 ◽

pp. 101-109

Author(s):

Laura E. Kuper ◽

Sunita Stewart ◽

Stephanie Preston ◽

May Lau ◽

Ximena Lopez

Keyword(s):

Mental Health ◽

Depressive Symptoms ◽

Suicidal Ideation ◽

Suicide Attempt ◽

Body Dissatisfaction ◽

Hormone Therapy ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Over Time

OBJECTIVES Our first aim was to examine baseline differences in body dissatisfaction, depression, and anxiety symptoms by gender, age, and Tanner (ie, pubertal) stage. Our second aim was to test for changes in youth symptoms over the first year of receiving gender-affirming hormone therapy. Our third aim was to examine potential differences in change over time by demographic and treatment characteristics. Youth experiences of suicidal ideation, suicide attempt, and nonsuicidal self-injury (NSSI) are also reported. METHODS Participants (n = 148; ages 9–18 years; mean age 14.9 years) were receiving gender-affirming hormone therapy at a multidisciplinary program in Dallas, Texas (n = 25 puberty suppression only; n = 123 feminizing or masculinizing hormone therapy). Participants completed surveys assessing body dissatisfaction (Body Image Scale), depression (Quick Inventory of Depressive Symptoms), and anxiety (Screen for Child Anxiety Related Emotional Disorders) at initial presentation to the clinic and at follow-up. Clinicians completed the Quick Inventory of Depressive Symptoms and collected information on youth experiences of suicidal ideation, suicide attempt, and NSSI. RESULTS Affirmed males reported greater depression and anxiety at baseline, but these differences were small (P < .01). Youth reported large improvements in body dissatisfaction (P < .001), small to moderate improvements in self-report of depressive symptoms (P < .001), and small improvements in total anxiety symptoms (P < .01). No demographic or treatment-related characteristics were associated with change over time. Lifetime and follow-up rates were 81% and 39% for suicidal ideation, 16% and 4% for suicide attempt, and 52% and 18% for NSSI, respectively. CONCLUSIONS Results provide further evidence of the critical role of gender-affirming hormone therapy in reducing body dissatisfaction. Modest initial improvements in mental health were also evident.

Download Full-text