Increase in Proportion of Th-17 Lymphocytes in Blood Heralds Overt Acute Graft Versus Host Disease in HSCT Patients.

Abstract IL-17 is involved in chronic inflammation and autoimmunity, this cytokine producing cells are well characterized in the mouse model. In man, situation is more complex due to the genetic variability, co-morbidities and environmental factors influencing the immune response. In patients post HSCT alloreactivity with the presence of aGvHD is a major factor affecting the outcome of transplantation. Understanding of the role of cells involved in regulation of the immune system is crucial for the treatment tailoring to favour tolerance but not making the recipient more prone to opportunistic infections and leukaemia relapse. In this study 27 patients post HSCT were investigated for the presence of regulatory cells and those producing IFNgamma and IL-17 in blood. Blood was collected at the time of haematological recovery or when the first clinical symptoms of aGvHD became apparent and then in one week intervals until +60 day post transplantation. PBMC were stimulated for 4 hrs with BD Leukocyte Activation Cocktail in the presence of Golgi Stop (BD, Erembodegen, Belgium) and then stained extracellularly with anti-CD4, permeabilized with Fixation/Permeabilization Concentrate and Diluent (eBioscience, San Diego, CA) and finally stained with anti-IFNgamma (BD), anti-IL-17 (eBioscience) anti FoxP3 (eBioscience). CD4+ cells subpopulations were analysed according to the expression of the stained features. It was found: FoxP3+CD4+ cells were in higher proportions in pts with aGvHD (results from all time-points taken together) (9.93%±0.61 vs 8.2%±0.50, n=98, p=0.040, U Mann-Whitney test) IFNgamma producing CD4+ lymphocytes were in higher proportions (0,34 vs 0.14, ns) in blood samples taken from patients lacking as compared to those having aGvHD. CD4+IL-17+ lymphocytes proportions increased from 1.39%±0.42 to 5.33%±2.45 (p=0.04, Wilcoxon Test for pairs) one week before aGvHD. Notably, at the time of full blown aGvHD the proportions of CD4+IL-17+ cells were lower as compared to the results of previous measurements (0.74%±0.29, p=0.008, Wilcoxon Test for pairs). Taking all results together the proportion of CD4+IL17+ lymphocytes were lower in patients having as compared to those lacking aGVHD (0.93%±0.27 vs 1,53%±0,41, p=0.05, U Mann-Whitney test). It appears that: FoxP3 positive cells expand during aGvHD likely as a response to alloreactive stimulation. INFgamma+ CD4+ cells benefit the course post HSCT making the patients less susceptible to aGvHD. CD4+IL17+ cells are likely involved at the early stage of aGvHD patho-mechanism heralding the clinical manifestation of this complication, but then they disappear from blood, possibly being marginalized in the inflamed tissues.

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PELATIHAN KOMUNIKASI INTERPERSONAL UNTUK MENINGKATKAN KOMITMEN ORGANISASI KARYAWAN

Al-Qalb : Jurnal Psikologi Islam ◽

10.15548/alqalb.v9i2.863 ◽

2019 ◽

Vol 9 (2) ◽

pp. 151-159

Author(s):

Nira Gusfika

Keyword(s):

Organizational Commitment ◽

Interpersonal Communication ◽

Communication Training ◽

Wilcoxon Test ◽

Control Group ◽

Test Results ◽

Whitney Test ◽

Mann Whitney Test ◽

Before And After ◽

Experimental Group

This study aims to determine the improvement of organizational commitment through interpersonal communication training. The hypothesis of this research is that there is a difference of organizational commitment to employees between before and after being given interpersonal communication training on experimental group, where the level of commitment of employee organization after being given interpersonal communication training is higher than the level of organizational commitment of the employees before being given interpersonal communication training. Second hypothesis, there is difference of posttest organizational commitment level between experiment group and control group, where posttest of organizational commitment in experiment group is higher than control group.The subject of this research is 17 employees at STAI YAPPTI Balaiselasa. Characteristics of the subjects of this study are employees who have levels of organizational commitment and interpersonal communication in the category very low, low and medium. The design used was Pretest-Posttest Control Group, while the data was collected using organizational commitment scale then analyzed using Mann Whitney test to see the difference of score between the experimental group who were given interpersonal communication training with the control group who were not given interpersonal communication training. Furthermore, Wilcoxon test was done for see experimental group scores between before and after interpersonal communication training.Based on Mann Whitney test results found Z = -3.447 (p <0.01), meaning there is a difference in scores between experimental groups who were trained with control groups who were not trained. Based on Wilcoxon test results found there was a difference between organizational commitment score in the experimental group between before and after being given interpersonal communication training with Z = -2,668 (p<0,01).

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Metabolism plays the key roles in Th cells differentiation

Reumatismo ◽

10.4081/reumatismo.2016.919 ◽

2016 ◽

Vol 68 (4) ◽

pp. 176 ◽

Cited By ~ 1

Author(s):

A. Hosseinzadeh ◽

S. Soukhtehzari ◽

M. Ghaedi ◽

R. Mansouri

Keyword(s):

T Cells ◽

Immune Cells ◽

Opportunistic Infections ◽

High Energy ◽

Cd4 Cells ◽

Health Studies ◽

Energy Consuming ◽

Hyper Sensitivity ◽

Process Studies

The increasing rate of autoimmunity in recent decades cannot be related to only genetic instabilities and disorders. Diet can directly influence our health. Studies have shown that there is a relationship between nutritional elements and alteration in the immune system. Among immune cells, the function of T lymphocyte is important in directing immune response. T CD4+ cells lead other immune cells to respond to pathogens by secreting cytokines. HIV+ patients, who have largely lost their T CD4+ cells, are susceptible to opportunistic infections, which do not normally affect healthy people. It seems that the metabolism of T cells is critical for their differentiation and their consequent functions. After activation, T cells need to undergo clonal expansion, which is a high energy- consuming process. Studies have shown that specific metabolites deprivation or their excess supply affects T CD4+cells subsets differentiation. Abnormal induction of subsets of T CD4+ cells causes some autoimmunity reactions and hyper-sensitivity as well, which may result from imbalance of diet uptake. In this mini-review, we describe the findings about fatty acids, glucose, amino acids, and vitamins, which are effective in determining the fates of T CD4+ cells. These findings may help us uncover the role of diet in autoimmune diseases.

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Efektifitas endorphin massage terhadap fungsi seksual perempuan pada masa menopause

Jurnal Kebidanan dan Keperawatan Aisyiyah ◽

10.31101/jkk.315 ◽

2018 ◽

Vol 13 (1) ◽

pp. 88-94

Author(s):

Sri Wahyuni ◽

Tutik Rahayu

Keyword(s):

Data Processing ◽

Sexual Function ◽

Wilcoxon Test ◽

P Value ◽

Female Sexual Function ◽

Z Score ◽

Whitney Test ◽

Mann Whitney Test ◽

Before And After

Abstract: The purpose of this study is to identify the effectiveness ofendorphine massage on female sexual function during menopause inNgampel District of Kendal Regency. Sampling was done by samplingcriteria acsidental aged less than 60 years old, have a husband, in a healthycondition. Data processing was performed using the Wilcoxon test todetermine differences in sexual function before and after the interventionwhile endorphine effectiveness of massage performed by using MannWhitney.Hasil research: Wilcoxon test showed that there are significantdifferences in sexual function before and after being given endorphineMassage with p value 0.00. While Mann Whitney test showed p value of0.13 and the value of z score of -2.828, which means there is a stronginfluence among endorphine Massage to increased sexual function soendorphine Massage is effective for improving sexual function.

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HUBUNGAN ACTIVITY DAILY LIVING (ADL) DENGAN KONTROL KADAR GLUKOSA DARAH (KGD) PADA PASIEN DIABETES MELITUS (DM) TIPE 2

Jurnal Ilmiah Keperawatan Imelda ◽

10.52943/jikeperawatan.v4i2.290 ◽

2018 ◽

Vol 4 (2) ◽

pp. 94-98

Author(s):

Ratna Dewi ◽

Wina Anggraeny

Keyword(s):

Daily Living ◽

Wilcoxon Test ◽

Cross Sectional ◽

Whitney Test ◽

Mann Whitney Test ◽

Diabetes Melitus

Aktivitas fisik merupakan salah satu penatalaksanaan DM tipe 2 yang bersifat nonfarmakologis dapat mempermudah perpindahan glukosa ke dalam sel-sel dan meningkatkan kepekaan terhadap insulin. Kedua tipe DM tipe 1 dan DM tipe 2 dengan melakukan aktivitas dan latihan fisik atau olahraga terbukti dapat meningkatkan pemakaian glukosa oleh sel sehingga KGD turun. Permasalahan penelitian adalah bagaimana hubungan ADL dengan kontrol KGD pada pasien DM tipe 2. Tujuan penelitian untuk menguji hubungan ADL dengan kontrol KGD pada pasien DM tipe 2. Jenis penelitian adalah korelasi dengan pendekatan pengamatan sewaktu (cross sectional). Penelitian dilaksanakan di . Sampel adalah seluruh penderita DM tipe 2 yang kontrol ke Puskesmas Bromo Medan sebesar 84 orang yang dibagi menjadi 2 kelompok, yaitu kelompok intervensi dan kontrol. Alat pengumpulan data menggunakan kuesioner. Uji yang digunakan adalah Wilcoxon test dan Mann whitney test. Hasil penelitian menunjukkan pesan singkat secara signifikan (p<0,05) memberikan dampak patuh terhadap aturan minum obat dan kontrol nilai KGD dibandingkan pasien DM tipe 2 yang tidak dilakukan pengiriman pesan singkat. Kesimpulan penelitian adalah pengiriman pesan singkat efektif meningkatkan kepatuhan minum obat dan kontrol nilai KGD untuk meningkatkan kulitas hidup penderita DM tipe 2. Disarankan kepada keluarga untuk rutin dalam perawatan dirumah dan mengingatkan cek KGD, pihak puskesmas mengadakan penyuluhan tentang pengelolaan penyakit DM setiap minggu, dan diharapkan pihak BPJS menambah program aktifitas reminder SMS dengan pengingat aturan minum obat ke peserta prolanis yang dilakukan pengiriman setiap hari.

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Pengaruh Range Of Motion Untuk Menurunkan Nyeri Sendi Pada lansia Dengan Osteoartritis di Wilayah Puskesmas Godean I Sleman Yogyakarta

Care Jurnal Ilmiah Ilmu Kesehatan ◽

10.33366/cr.v6i1.785 ◽

2018 ◽

Vol 6 (1) ◽

pp. 36

Author(s):

Maruli Taufandas ◽

Elsye Maria Rosa ◽

Moh Afandi

Keyword(s):

Range Of Motion ◽

Wilcoxon Test ◽

Control Group ◽

P Value ◽

Control Group Design ◽

Whitney Test ◽

Group Design ◽

Mann Whitney Test

Salah satu penyakit degeneratif pada lansia yang sering dialami yaitu osteoartritis, yang ditandai dengan adanya nyeri pada ekstremitas bawah dan prevalensinya semakin meningkat dengan bertambahnya usia. Penatalaksanaan non farmakologi merupakan komponen yang sangat penting dalam mengatasi nyeri, salah satu bentuknya adalah latihan Range of Motion. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh Range of Motion untuk menurunkan nyeri sendi pada lansia dengan osteoartritis di wilayah kerja Puskesmas Godean I Sleman Yogyakarta. Metode :Penelitian ini adalah study intervensi berupa penelitian kuantitatifdengan rancangan Quasi Eksperiment Design: Pretest-Posttest Control Group Design. Penelitian dilakukan di dua dusun di Kabupaten Sleman yaitu di dusun Mertosutan dan dusun Ngabangan.Sampel pada penelitian ini sebanyak 36 orang lansia dengan masing-masing 18 lansia sebagai kelompok intervensi dan 18 lansia sebagai kelompok kontrol.Pengambilan sampel menggunakan teknik purposive sampling.Analisis data yang digunakan adalah Wilcoxon Test dan Mann Whitney Test. Hasil : Setelah melakukan latihan Range of Motionselama 4 minggu, didapatkan hasil bahwa terdapat pengaruh Range of Motion terhadap skala nyeri sendi pada lansia dengan osteoartritis dengan p value 0,000 (α < 0,05). Kesimpulan :Range of Motion berpengaruh secara signifikan terhadap penurunan tingkat skala nyeri sendi pada lansia dengan osteoartritis

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Pengaruh Diabetes Self Management Education (DSME) terhadap Self Management pada Pasien Diabetes Mellitus

Jurnal Ilmiah Kesehatan ◽

10.48144/jiks.v12i2.174 ◽

2019 ◽

Vol 12 (2) ◽

Author(s):

Trina Kurniawati ◽

Titih Huriah ◽

Yanuar Primanda

Keyword(s):

Diabetes Mellitus ◽

Management Education ◽

Intervention Group ◽

Simple Random Sampling ◽

Wilcoxon Test ◽

Self Management ◽

Control Group ◽

P Value ◽

Whitney Test ◽

Mann Whitney Test

AbstrakEdukasi kepada pasien Diabetes Mellitus (DM) yang dapat memperbaiki hasil klinis adalah Diabetes Self Management Education (DSME). DSME merupakan salah satu metode yang dapat memfasilitasi pengetahuan dan keterampilan. Penelitian ini bertujuan untuk mengetahui pengaruh Diabetes Self Management Education terhadap Self Management pada pasien DM. Penelitian ini menggunakan metode penelitian quasi experimental dengan control group pre test- post test design. Teknik pengambilan sampel menggunakan teknik Simple random sampling dengan jumlah sampel sebanyak 46 orang yang terbagi menjadi 23 orang pada kelompok intervensi mendapatkan DSME sebanyak 4 sesi dalam satu bulan dan 23 orang pada kelompok kontrol mendapatkan edukasi dari Program PERSADIA. Instrumen yang digunakan menggunakan kuesioner. Analisis statistik menggunakan Wilcoxon dan Mann Whitney test. Hasil penelitian menunjukkan bahwa P value uji Wilcoxon test sebesar 0,000 pada kelompok intervensi, P value uji Mann Whitney test adalah 0,000 pada variabel self management. Berdasarkan hasil uji statistik didapatkan p<0,05 yang menunjukkan bahwa terdapat perbedaan nilai self management antara kelompok intervensi dengan kelompok kontrol secara signifikan. Kesimpulan penelitian ini adalah DSME dapat meningkatkan self management pada pasien DM. Disarankan petugas kesehatan dapat memberikan DSME untuk meningkatkan self management pasien diabetes dan menggunakan DSME sebagai program promosi kesehatan.Kata kunci: Diabetes Mellitus; DSME;Self Management The Influnce of Diabetes Self Management Education (DSME) to the Self Management on the Diabetes Patient AbstractEducation to patients Diabetes Mellitus (DM) who can improve clinical outcomes is Diabetes Self Management Education (DSME). DSME is one method that can facilitate knowledge and skills. The purpose of this research is to determine the effect of Diabetes Self Management Education (DSME) to Self Management on the diabetes patients. This study is used the quasi experimental research method with control group pre test post test design. The sampling technique used Simple random sampling with a samples of 46 people and it is devided 23 people in the intervention group get DSME as much as 4 sessions in one month and 23 people in the control group get education programe at PERSADIA. The instrument used was questionnaire. Statistical analysis used Wilcoxon and Mann Whitney test. The results showed that P value of Wilcoxon test was 0.000 in the intervention group, P test value of Mann Whitney test was 0.000 in self management variable. Based on statistical test results obtained p <0.05 which indicates that there are differences in self-management value between the intervention group and the control group significantly. The conclusions of this research is DSME can improve self-management on the patients with diabetes. It is recommended that health workers can provide DSME to improve self-management in diabetic patients and use DSME as a health promotion program.Keywords : Diabetes Mellitus, DSME, Self Management

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Frequency and Functional Analysis of Myeloid-Derived Suppressor Cells (MDSCs) in the Peripheral Blood and Bone Marrow of Patients with Chronic Idiopathic Neutropenia (CIN)

Blood ◽

10.1182/blood-2020-136500 ◽

2020 ◽

Vol 136 (Supplement 1) ◽

pp. 26-27

Author(s):

Nikoleta Bizymi ◽

Athina Damianaki ◽

Maria Velegraki ◽

Konstantina Zavitsanou ◽

Anastasios Karasachinidis ◽

...

Keyword(s):

Bone Marrow ◽

T Cell ◽

Suppressor Cells ◽

Wilcoxon Test ◽

Healthy Controls ◽

Myeloid Derived Suppressor Cells ◽

Whitney Test ◽

Mann Whitney Test ◽

Chronic Idiopathic Neutropenia ◽

Paired Analysis

Myeloid-derived suppressor cells (MDSCs) are myeloid cells with immunoregulatory properties characterized mainly by suppression of T-cell responses (Bizymi et al, HemaSphere 2019). They are divided in HLA-DRlow/-/CD11b+/CD33+/CD15+ polymorphonuclear (PMN-MDSCs) and HLA-DRlow/-/CD11b+/CD33+/CD14+ monocytic (M-MDSCs) subsets and they are implicated in inflammatory and malignant diseases. Chronic idiopathic neutropenia (CIN), is a (usually benign) neutrophil disorder characterized by persistent and unexplained neutropenia following a detailed clinical/laboratory investigation including anti-neutrophil antibody testing, bone marrow (BM) biopsy and karyotype (Dale & Bolyard, Curr Opin Hematol 2017). Previous studies have shown that neutropenia in CIN is associated with increased apoptosis of BM granulocytic progenitor cells due to an inflammatory BM microenvironment consisting of oligoclonal T-lymphocytes, proinflammatory monocytes and proapoptotic cytokines. The aim of the present study is to explore the possible involvement of the MDSCs in the pathophysiology of CIN by investigating their number in peripheral blood (PB) and BM in association with their functional characteristics. We have studied 100 CIN patients and 49 age- and sex-matched healthy controls. The patients fulfilled the previously described diagnostic criteria for CIN (Papadaki et al, Blood 2003) and had mean neutrophil counts 1095.67 ± 479.52 (median 1215, range 100-1700). MDSC subsets were quantitated by flow cytometry in the PB mononuclear cell (PBMC) fraction using the combination of CD33PC7/CD15PC5/HLA-DRECD/CD14PE/CD11bFITC monoclonal antibodies and the Kaluza analysis software. MDSC subsets were also studied in the BMMC fraction of 24 CIN patients and 8 healthy controls from the study population. The T-cell suppression function of patient MDSCs was evaluated in coculture experiments of immunomagnetically sorted, CFSE stained, normal CD3+ cells with immunomagnetically sorted M-MDSCs and PMN-MDSCs from 4 patients and 4 healthy donors using recombinant human IL-2 as activating factor. CFSE staining was detected in the CD3+ cells on day 0 and day 3 of coculture and analysis was performed with the Fcs Express 7 software. Statistical analysis was performed with the Statistica software. We found that the proportion of PB M-MDSCs was statistically significant lower in CIN patients (1.45% ± 1.82%) compared to controls (3.68% ± 3.12%, Mann-Whitney test, p < 0.0001) (Figure a) whereas the proportion of PB PMN-MDSCs, although lower in patients, did not differ significantly from the controls. The proportion of BM M-MDSCs did not differ significantly between CIN patients and controls whereas the proportion of BM PMN-MDSCs was statistically significant lower in patients (13.27% ± 11.27%) compared to controls (19.49% ± 4.46%; Mann-Whitney test, p = 0.0291) (Figure b). Paired analysis showed that the proportion of PMN-MDSCs were higher in the BMMC compared to PBMC fraction in both CIN patients (13.27% ± 11.27% vs 1.14% ± 1.64%, respectively; Wilcoxon test, p = 0.005) (Figure c) and healthy controls (19.49% ± 4.46% vs 9.92% ± 9.08%, respectively; Wilcoxon test, p = 0.0118). Interestingly, the proportion of increase of PMN-MDSCs (in BMMC vs PBMC fraction) was significantly higher in patients (86.71% ± 21.26%) compared to controls (55.95% ± 38.59%; Mann-Whitney test, p = 0.0357) (Figure d). The above data indicate low production of PMN-MDSCs in CIN patients compared to controls but a trend for accumulation of these cells in patients' BM. No statistically significant difference was documented in paired analysis of M-MDSCs between BMMC and PBMC fractions in either CIN patients or healthy controls. Patient PMN-MDSCs and M-MDSCs displayed normal capacity to suppress T-cell proliferation as was indicated by the T-cell generations in coculture experiments of normal CD3+ cells in the presence or absence of patient MDSCs (Figure e). In conclusion, CIN patients display low proportion of MDSCs in the PB and lower proportion of PMN-MDSC in the BM compared to normal individuals. Patient MDSCs display normal capacity to suppress T-cell activation. The low proportions of MDSCs may sustain the inflammatory process associated with CIN whereas the accumulation of PMN-MDSCs in the BM represents probably a compensatory mechanism to suppress the inflammatory processes within patients' BM microenvironment. Figure Disclosures Papadaki: Genesis pharma SA: Membership on an entity's Board of Directors or advisory committees, Research Funding.

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EFEKTIVITAS PEER EDUCATION UNTUK REMAJA DALAM MENINGKATKAN PENGETAHUAN DAN SIKAP PENCEGAHAN HIV AIDS

JURNAL KESEHATAN MASYARAKAT ◽

10.47317/jkm.v12i1.147 ◽

2019 ◽

Vol 12 (1) ◽

Author(s):

Dewi Ariyani Wulandari ◽

Nur Yeti Syarifah

Keyword(s):

Sustainable Development ◽

Peer Education ◽

Wilcoxon Test ◽

Sustainable Development Goal ◽

Development Goal ◽

Whitney Test ◽

Group Design ◽

Mann Whitney Test ◽

Peer Educator ◽

Hiv Aids

ABSTRAKSalah satu target tujuan dari pembangunan berkelanjutan (Sustainable Development Goal/SDG) adalahmenghentikan epidemik HIV AIDS di dunia tahun 2030. Usia remaja adalah usia berpotensi terinfeksiHIV AIDS. Salah satu upaya pencegahan HIV AIDS pada remaja adalah pendidikan kesehatan denganmetode peer education (pendidikan teman sebaya). Kelompok teman sebaya merupakan sumber referensiutama bagi remaja dalam hal persepsi dan sikap yang berkaitan dengan gaya hidup. Tujuan Penelitian iniadalah mengetahui efektivitas peer education terhadap pengetahuan dan sikap upaya pencegahan HIVAIDS remaja di Kabupaten Sleman. Desain penelitian quasi eksperimen dengan pre-post and post-testcontrol group design. Sampel penelitian ini terdiri atas 76 responden. Kelompok intervensi terdiri atas 38responden menggunkan teknik peer education dengan melatih peer educator dan kelompok kontrol terdiriatas 38 responden menggunakan metode ceramah. Pemilihan sampling mengguakan teknik purposivesampling yang dilakukan pada dua SMA. Instrumen penelitian menggunakan kuesioner. Tahapan analisisdata dengan menggunakan Wilcoxon dan Mann Whitney test untuk analisa bivariat. Hasil penelitiandengan menggunakan Wilcoxon test menunjukkan bahwa terdapat perbedaan tingkat pengetahuan(p=0,000) dan sikap (p=0,000) secara bermakna antara sebelum dan sesudah intervensi metode peereducation maupun metode ceramah. Hasil Mann Whitney test menunjukkan bahwa terdapat perbedaanbermakna tingkat pendidikan (p=0,000) dan sikap (0,000) antara metode peer education dengan metodeceramah. Pendidikan kesehatan dengan metode peer education lebih efektif meningkatkan pengetahuandan sikap upaya pencegahan HIV AIDS pada remaja.

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The Analysis of Administrators and Staffs Attitude from the Obstacles of Delegation of Authority

Journal of Management and Sustainability ◽

10.5539/jms.v6n2p108 ◽

2016 ◽

Vol 6 (2) ◽

pp. 108

Author(s):

Hamed Mohammadi ◽

Fatemeh Habibi ◽

Mohammad Babaei ◽

Zohreh Afzali

Keyword(s):

Two Dimensions ◽

Wilcoxon Test ◽

Friedman Test ◽

Mazandaran Province ◽

Whitney Test ◽

Delegation Of Authority ◽

Mann Whitney Test ◽

Research Questions ◽

Controlling Processes ◽

Smirnov Test

This study was conducted to analyze the managers’ and employees’ attitude towards obstacles to devolutionin Mazandaran Province Gas Company (Iran). According to the exploratory studies, devolutionobstacles was explored and identified at two dimensions including managers’ unwillingness to devolutionand subordinates’ reluctance to accept authority. To analyze the data and to confirm or reject the research questions, first, the Kolmogorov-Smirnov test was used to determine the normality of data. Given the non-normality of data, non-parametric tests such as one-sample one-tailed Wilcoxon test, Friedman test for ranking components, and Mann–Whitney test were used to identify the employees’ and managers’ different perception of obstacles to delegation of authority. Findings of the study indicated that Wilcoxon test was not significant at o.o5; that is, lack of trust and confidence in subordinates, inability of managers in guiding subordinates, lack of controlling processes, managers’ sense of insecurity, and unwillingness of managers to delegate authority were not the main obstacles to devolutionby managers in Mazandran Province Gas Company, and their effects were not significant. In line with examining the obstacles effective to the devolutionby subordinates, it was found that the fear of criticism, blame, and dismissal along with the lack of adequate motivation in subordinates were recognized as the most important obstacles to adoption of authority by subordinates in Mazandran Province Gas Company.

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Comparison of Muscle Strength in Stroke Patients between The Given and Not Given Range of Motion Exercise

Nurse Media Journal of Nursing ◽

10.14710/nmjn.v5i2.10534 ◽

2015 ◽

Vol 5 (2) ◽

pp. 88

Author(s):

Eka Rhestifujiayani ◽

Emil Huriani ◽

Muharriza Muharriza

Keyword(s):

Muscle Strength ◽

Lower Extremities ◽

Nursing Intervention ◽

Upper Extremities ◽

Wilcoxon Test ◽

Control Group ◽

P Value ◽

Stroke Patients ◽

Whitney Test ◽

Mann Whitney Test

Background: Hemiparesis is a common problem that can caused disability. ROM Exercise is an exercise that to performed evaluate and to improv the function of the musculoskeletal system and is one of therapies in stroke patients that aim to increase cerebral blood flow, minimize disability caused by stroke, so can refine sensory motoric function.Purpose: The objective of this study was to examine the effect ROM exercises of the extremity muscle strength in patients with stroke Methods: This study was a quasi experimental with non equivalent control group design. The sampling technique was purposive sampling. The number of sample was 20 respondents. The statistical test used are Wilcoxon test and Mann-Whitney test. Result: Wilcoxon test in control group showed p-value in upper extremities was p=0,157 and in lower extremities was p=0,083, it mean that there was no increase in muscle strength in the control group and in experiment group showed p-value in upper extremities was p=0,004 and in lower extremities was p=0,005, it mean that there is increase in muscle strength in the experiment group. The result of Mann-Whitney test showed p-value in upper extremities was p=0,002 and in lower extremities was p=0,006, it means that there were differences in the increase in muscle strength between control group and experiment group. Conclusion: ROM exercises affect the increase in muscle strength in stroke patients with hemiparesis. The ROM exercises can be used as a nursing intervention in the provision of nursing care.

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