scholarly journals Occurrence and multidrug resistance of Campylobacter spp. at duck farms and associated environmental and anthropogenic risk factors in Bangladesh

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Md. Nasir Uddin ◽  
Sucharit Basu Neogi ◽  
Sk Shaheenur Islam ◽  
Jannatul Ferdous ◽  
Md. Shahidur Rahman Khan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Health Sector ◽  
Cloacal Swab ◽  
Negative Influence ◽  
Anthropogenic Factors ◽  
Multi Drug Resistance ◽  
Related Factors ◽  
Zoonotic Pathogens ◽  
Human Interface ◽  
Associated Risk Factors

Abstract Background The alarming rise in multi-drug resistant (MDR) zoonotic pathogens, including Campylobacter spp., has been threatening the health sector globally. In Bangladesh, despite rapid growth in poultry sector little is known about the potential risks of zoonotic pathogens in homestead duck flocks. The aim of this study was to understand the occurrence, species diversity, and multi-drug resistance in Campylobacter spp., and identify the associated risk factors in duck farms in Bangladesh. Methods The study involved 20 duck farms at 6 sub-districts of Mymensingh, Bangladesh. Monthly occurrence of Campylobacter spp. in potential sources at the farms during February-September, 2018, was detected by culture and PCR-based methods. Campylobacter isolates were examined for resistance to different antimicrobials. Risk factors, concerning climatic and environmental disposition, farm management, and anthropogenic practices, of Campylobacter infection were estimated by participatory epidemiological tools. Results Occurrence of Campylobacter spp. was detected in overall 36.90% (155/420) samples, more frequently in drinking water (60%, 30/50), followed by cloacal swab (37.50%, 75/200), egg surface swab (35%, 35/100) and soil of the duck resting places (30%, 15/50) but was not detected in feed samples (n = 20). PCR assays distinguished the majority (61.30%, 95/155) of the isolates as C. coli, while the rest (38.70%, 60/155) were C. jejuni. Notably, 41.7% (25/60) and 31.6% (30/95) strains of C. jejuni and C. coli, respectively, were observed to be MDR. The dynamics of Campylobacter spp., distinctly showing higher abundance during summer and late-monsoon, correlated significantly with temperature, humidity, and rainfall, while sunshine hours had a negative influence. Anthropogenic management-related factors, including, inadequate hygiene practices, use of untreated river water, wet duck shed, flock age (1–6 months), and unscrupulous use of antimicrobials were identified to enhance the risk of MDR Campylobacter infection. Conclusion The present study clearly demonstrates that duck farms contribute to the enhanced occurrence and spread of potentially pathogenic and MDR C. coli and C. jejuni strains and the bacterial dynamics are governed by a combined interaction of environmental and anthropogenic factors. A long-term holistic research at the environment-animal-human interface would be integral to divulge health risk reduction approaches tackling the spread of Campylobacter spp. from duck farms.

scholarly journals Magnitude of spontaneous preterm birth and its associated factors among preterm birth in NICU wards in Asella Teaching and Referral Hospital, Asella, Oromia, Ethiopia

2021 ◽  
Vol 49 (8) ◽  
pp. 030006052110346
Author(s):  
Techane Sisay Tuji ◽  
Addisu Dabi Wake ◽  
Gezahegn Badeg Adere ◽  
Aselefu Beka Wedajo ◽  
Batu Dekeba Obole ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Healthcare Providers ◽  
Preterm Births ◽  
Cross Sectional Study ◽  
Spontaneous Preterm Birth ◽  
Related Factors ◽  
Cross Sectional ◽  
Bivariate Logistic Regression ◽  
Associated Risk Factors

Objective To assess the prevalence of spontaneous preterm births and to identify the associated risk factors. Methods This single-centre cross-sectional study enrolled women that experienced a preterm birth as registered on the neonatal log-book between 30 December 2019 and 30 December 2020. A pre-tested structured checklist was used to collect data (sociodemographic characteristics; obstetric-related factors; medical history; and pregnancy-related factors). Bivariate logistic regression analyses were applied to identify factors associated with spontaneous preterm birth. A multivariate model identified significant independent risk factors. Results A total of 310 patients participated in the study. The prevalence of spontaneous preterm birth in this population was 67.1% (208 of 310; 95% confidence interval [CI] 61.5, 71.9). Patients without a partner (adjusted odds ratio [AOR] = 1.470, 95% CI 1.23, 4.42), patients residing in a rural area (AOR = 2.51, 95% CI 1.123, 5.513) and those with a history of PIH during their current pregnancy (AOR = 0.104, 95% CI 0.053, 0.014) were significantly more likely to have a spontaneous preterm birth. Conclusion The prevalence of spontaneous preterm birth in in this study was high. Healthcare providers and all stakeholders should focus on screening pregnant women at the risk of spontaneous preterm birth.

scholarly journals Incidence and risk factors for deep venous thrombosis of lower extremity after surgical treatment of isolated patella fractures

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zhanchao Tan ◽  
Hongzhi Hu ◽  
Xiangtian Deng ◽  
Jian Zhu ◽  
Yanbin Zhu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lower Extremity ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Medical Data ◽  
Limited Information ◽  
Related Factors ◽  
Patella Fractures ◽  
Independent Risk Factors ◽  
Associated Risk Factors

Abstract Background Limited information exists on the incidence of postoperative deep venous thromboembolism (DVT) in patients with isolated patella fractures. The objective of this study was to investigate the postoperative incidence and locations of deep venous thrombosis (DVT) of the lower extremity in patients who underwent isolated patella fractures and identify the associated risk factors. Methods Medical data of 716 hospitalized patients was collected. The patients had acute isolated patella fractures and were admitted at the 3rd Hospital of Hebei Medical University between January 1, 2016, and February 31, 2019. All patients met the inclusion criteria. Medical data was collected using the inpatient record system, which included the patient demographics, patient’s bad hobbies, comorbidities, past medical history, fracture and surgery-related factors, hematological biomarkers, total hospital stay, and preoperative stay. Doppler examination was conducted for the diagnosis of DVT. Univariate analyses and multivariate logistic regression analyses were used to identify the independent risk factors. Results Among the 716 patients, DVT was confirmed in 29 cases, indicating an incidence of 4.1%. DVT involved bilateral limbs (injured and uninjured) in one patient (3.4%). DVT involved superficial femoral common vein in 1 case (3.4%), popliteal vein in 6 cases (20.7%), posterior tibial vein in 11 cases (37.9%), and peroneal vein in 11 cases (37.9%). The median of the interval between surgery and diagnosis of DVT was 4.0 days (range, 1.0-8.0 days). Six variables were identified to be independent risk factors for DVT which included age category (> 65 years old), OR, 4.44 (1.34-14.71); arrhythmia, OR, 4.41 (1.20-16.15); intra-operative blood loss, OR, 1.01 (1.00-1.02); preoperative stay (delay of each day), OR, 1.43 (1.15-1.78); surgical duration, OR, 1.04 (1.03-1.06); LDL-C (> 3.37 mmol/L), OR, 2.98 (1.14-7.76). Conclusion Incidence of postoperative DVT in patients with isolated patella fractures is substantial. More attentions should be paid on postoperative DVT prophylaxis in patients with isolated patella fractures. Identification of associated risk factors can help clinicians recognize the risk population, assess the risk of DVT, and develop personalized prophylaxis strategies.

scholarly journals Occurrence, associated risk factors, and treatment of surgical site infections in Pakistan

2020 ◽  
Vol 18 ◽  
pp. 205873922096054
Author(s):  
Faiz Ullah Khan ◽  
Yu Fang ◽  
Zakir Khan ◽  
Farman Ullah Khan ◽  
Zafar Iqbal Malik ◽  
...  
Keyword(s):  
Risk Factors ◽  
Transurethral Resection ◽  
Surgical Site Infections ◽  
Exploratory Laparotomy ◽  
Cross Sectional Study ◽  
Surgical Patients ◽  
Related Factors ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Associated Risk Factors

Globally, surgical site infections are one of the common infections which lead to a large amount of mortality and morbidity in postsurgical care. The risk for surgical site infection is multidimensional which includes mainly; patient, surgery, and hospital-related factors. This study is aimed to determine the burden of SSIs along with contributed risk factors. A prospective observational cross-sectional study was conducted in one of the largest public-sector hospitals in Pakistan. A total of 412 patients were recruited in the study with full consent and monitored for 30 days after surgery with direct and indirect surveillance. Overall, in seven different surgical procedures the incidence (29.8%) rate of SSI was observed; in appendectomy ( n = 17, 4.1%), exploratory laparotomy ( n = 51, 12.6%), laparoscopic cholecystectomy ( n = 12, 2.90%), mesh repair ( n = 17, 4.01%), thyroidectomy (5, 1.2%), transurethral resection of the prostate ( n = 11, 2.6%), and transurethral resection of the bladder (10, 2.4%). The average SSI rate in every single procedure was about 18 (4.27%) per surgical procedure out of 123 (29.85%) SSI cases. Types of SSI identified were superficial, deep incisional and organ/space ( n = 76, 18.4%, n = 23, 5.5%, and n = 24, 5.7%). Incidence of SSIs during admission, at readmission, and post-surveillance cases were ( n = 50, 12.1%, n = 25, 6.0% and n = 48, 11.6%). Associated risk factors found contributed to the incidence of SSI ( p < 0.05). Pre-operative ( n = 348, 84.5%) and 6 (1.5%) surgical patients did not received the post-operative antibiotics. The P. aeruginosa ( n = 15, 12.1%) and S. aureus (13, 10.5%). Cefoperazone and sulbactam were the most prescribed antibiotics. Associated risk factors and treatment outcomes of surgical patients have a direct association with the incidence of SSI. Hospital-based antimicrobial stewardship, implementation of surgical guidelines, patient care, and education are needed to develop at wards level in hospitals.

Recurrent Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Directions

2021 ◽  
Author(s):  
Kristel K. Leung ◽  
Maya Deeb ◽  
Sandra E. Fischer ◽  
Aliya Gulamhusein
Keyword(s):  
Risk Factors ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Large Scale ◽  
Related Factors ◽  
Future Directions ◽  
History Of ◽  
Inflammatory Bowel ◽  
Specific Factors ◽  
Associated Risk Factors

AbstractPatients with primary sclerosing cholangitis (PSC) constitute 5 to 15% of patients listed for liver transplantation worldwide. Although post-transplant outcomes are favorable, recurrent PSC (rPSC) occurs in an important subset of patients, with higher prevalence rates reported with increasing time from transplant. Given its association with poor graft outcomes and risk of retransplant, effort has been made to understand rPSC, its pathophysiology, and risk factors. This review covers these facets of rPSC and focuses on implicated risk factors including pretransplant recipient characteristics, inflammatory bowel-disease-related factors, and donor-specific and transplant-specific factors. Confirming a diagnosis of rPSC requires thoughtful consideration of alternative etiologies so as to ensure confidence in diagnosis, management, subsequent risk assessment, and counseling for patients. Unfortunately, no cure exists for rPSC; however, future large-scale efforts are underway to better characterize the natural history of rPSC and its associated risk factors with hopes of identifying potential key targets for novel therapies.

scholarly journals Glucose- and glycaemic factor-lowering effects of probiotics on diabetes: a meta-analysis of randomised placebo-controlled trials

2016 ◽  
Vol 115 (7) ◽  
pp. 1167-1177 ◽  
Author(s):  
Jing Sun ◽  
Nicholas J. Buys
Keyword(s):  
Risk Factors ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Mean Difference ◽  
Controlled Trials ◽  
Model Assessment ◽  
Related Factors ◽  
Evidence Database ◽  
Associated Risk Factors

AbstractThis meta-analysis examined the effect of probiotics on glucose and glycaemic factors in diabetes and its associated risk factors. All randomised-controlled trials published in English in multiple databases from January 2000 to June 2015 were systematically searched. Only studies that addressed glucose- and glycaemic-related factors as outcome variables were included. The main outcomes of interest in trials were mean changes in glucose, HbA1c, insulin and homoeostasis model assessment-estimated insulin resistance (HOMA-IR). Using the Physiotherapy Evidence Database (PEDro) scale to assess the quality of studies, a total of eleven studies with 614 subjects were included. The pooled mean difference and effect size with a 95 % CI were extracted using a random-effect model. It was found that there are statistically significant pooled mean differences between the probiotics and the placebo-controlled groups on the reduction of glucose (−0·52 mmol/l, 95 % CI −0·92, −0·11 mmol/l; P=0·01) and HbA1c (−0·32 %, 95 % CI −0·57, −0·07 %; P=0·01). There was no statistically significant pooled mean difference between the probiotics and the placebo-controlled groups on the reduction of insulin (−0·48 µIU/ml, 95 % CI −1·34, 0·38 µIU/ml; P=0·27) and HOMA-IR (pooled effect of –0·44, 95 % CI −1·57, 0·70; P=0·45). Meta-regression analysis identified that probiotics had significant effects on reduction of glucose, HbA1c, insulin and HOMA-IR in participants with diabetes, but not in participants with other risk factors. The present meta-analysis suggested that probiotics may be used as an important dietary supplement in reducing the glucose metabolic factors associated with diabetes.

Exploring the musculoskeletal problems and associated risk-factors among brick kiln workers

2018 ◽  
Vol 11 (6) ◽  
pp. 395-410 ◽  
Author(s):  
Manoj Kumar Sain ◽  
M.L. Meena
Keyword(s):  
Risk Factors ◽  
Musculoskeletal Symptoms ◽  
Entire Body ◽  
Brick Kiln ◽  
Related Factors ◽  
Content Type ◽  
Body Regions ◽  
Lower Back ◽  
Musculoskeletal Problems ◽  
Associated Risk Factors

Purpose Prolonged working in repetitive and awkward postures can result in musculoskeletal disorders among workers involved in labour-intensive jobs like those of brick kiln workers. Unlike other labour-intensive sectors, workers in this particular sector have a lack of awareness about musculoskeletal problems. Therefore, the purpose of this paper is to explore musculoskeletal issues and associated risk-factors among brick kiln workers. Design/methodology/approach A questionnaire survey was conducted among 217 male and 111 female workers aged between 17 and 53 years. They were employed in traditional brick kiln units situated in Rajasthan, India. Postures were analysed by Rapid Upper Limb Assessment and Rapid Entire Body Assessment methods. Binary logistic regression was used to find the association between musculoskeletal problems and risk-factors. Findings For the mould evacuating task, wrist (76.2 per cent) and lower back (56 per cent) issues were the most frequently reported musculoskeletal problems, while in spading task, lower back (62.4 per cent) and shoulder (57.7 per cent) problems were prominent. Musculoskeletal symptoms in one or more body regions were associated with personal and work-related factors including the type of task and experience. Research limitations/implications Kiln workers are exposed to high musculoskeletal and postural risks, particularly in spading and mould filling tasks. To reduce these risks, ergonomic interventions are needed. Originality/value It is recognised that the musculoskeletal health of brick kiln workers is a cause for concern. The present study provides the evidence of the prevalence of musculoskeletal symptoms experienced by brick kiln workers and the association of symptoms with various risk-factors, which has not been addressed in previous studies.

scholarly journals Incidence and Risk Factors for Deep Venous Thrombosis of Lower Extremity After Surgical Treatment of Isolated Patella Fractures

2020 ◽  
Author(s):  
Zhanchao Tan ◽  
Hongzhi Hu ◽  
Xiangtian Deng ◽  
Jian Zhu ◽  
Yanbin Zhu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lower Extremity ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Medical Data ◽  
Limited Information ◽  
Related Factors ◽  
Patella Fractures ◽  
Independent Risk Factors ◽  
Associated Risk Factors

Abstract Background: Limited information exists on the incidence of postoperative deep venous thromboembolism (DVT) in patients with isolated patella fractures. The objective of this study was to investigate the postoperative incidence and locations of deep venous thrombosis (DVT) of the lower extremity in patients underwent isolated patella fractures and to identify the associated risk factors.Methods: We collected the medical data of 716 hospitalized patients with acute isolated patella fracture who presented at the 3rd Hospital of Hebei Medical University between January 1, 2016, and February 31, 2019 and all patients met the inclusion criteria. Medical data were collected using the inpatient record system, including the patient demographics, patient’s bad hobbies, comorbidities, past medical history, fracture and surgery-related factors, and hematological biomarkers, total hospital stay, preoperative stay. Doppler examination was conducted for the diagnosis of DVT, Univariate analyses and multivariate logistic regression analyses were used to identify the independent risk factors.Results: Among the 716 patients, DVT was confirmed in 29 cases, indicating an incidence of 4.1%. DVT involved bilateral limbs (injured and uninjured) in one patient (3.4%). DVT involved superficial femoral common vein in 1 case (3.4%), popliteal vein in 6 cases (20.7%), posterior tibial vein in 11 cases (37.9%), and peroneal vein in 11 cases (37.9%). The median of the interval between surgery and diagnosis of DVT was 4.0 days (range: 1.0 to 8.0 days). Six variables were identified to be independent risk factors for DVT, including age category (>65 years old), OR, 4.44 (1.34 - 14.71), arrhythmia, OR, 4.41(1.20 - 16.15), intra-operative blood loss, OR, 1.01 (1.00 - 1.02), preoperative stay (delay of each day), OR, 1.43 (1.15 - 1.78). Surgical duration, OR, 1.04 (1.03 - 1.06), LDL-C (> 3.37 mmol/L), OR, 2.98 (1.14 - 7.76).Conclusion: Incidence of postoperative DVT in patients with isolated patella fractures is not low. More attentions should be paid on postoperative DVT prophylaxis in patients with isolated patella fractures. Identification of associated risk factors can help clinicians recognize the risk population, assess the risk of DVT and develop personalized prophylaxis strategies.

scholarly journals Prevalence of Low Back Pain and Associated Risk Factors among Nurses at King Abdulaziz University Hospital

2021 ◽  
Vol 18 (4) ◽  
pp. 1567
Author(s):  
Aishah Almaghrabi ◽  
Fatmah Alsharif
Keyword(s):  
Risk Factors ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Related Factors ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Work Related ◽  
King Abdulaziz University ◽  
Associated Risk Factors

Aim: To determine the prevalence of LBP and the associated risk factors among nurses at King Abdulaziz University Hospital (KAUH). Methods: A cross-sectional study design was adopted with a convenience sample of 234 nurses recruited from nine different departments at KAUH in Jeddah, Saudi Arabia. Participants completed the questionnaire, which had two parts: Part I: Socio-demographic data, medical factors, and work-related factors; and Part II: Standardized Nordic Musculoskeletal Questionnaire was used to obtain data. Data collection was carried out from March to April 2020. Data were analyzed using the SPSS version 22. Results: Cumulative prevalence of LBP was 82.9%, annual prevalence was 85.5%, while one-week prevalence of LBP was 53.6%. The factor significantly associated with LBP over the past 12 months was manual lifting of patients (p = 0.030). Nurses working in surgical wards had higher prevalence of LBP. About 24.7% of them changed their working unit, hospitalization was necessary for 11.9%, and 39.8% sought medical care. Conclusions: The findings from this study may better enable policymakers to adopt certain strategies toward reducing the burdens and challenges of LBP among nurses.

scholarly journals Common bacterial causes of external ocular infections, associated risk factors and antibiotic resistance among patients at ophthalmology unit of Felege Hiwot Referral Hospital, Northwest Ethiopia: a cross-sectional study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zimam Ayehubizu ◽  
Wondemagegn Mulu ◽  
Fantahun Biadglegne
Keyword(s):  
Risk Factors ◽  
Susceptibility Testing ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Multi Drug Resistance ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ocular Infections ◽  
Felege Hiwot Referral Hospital ◽  
Associated Risk Factors

Abstract Background Ocular infections are a serious public health problem in Ethiopia with increased incidence of morbidity and blindness. Empirical therapy with topical ophthalmic broad spectrum antibiotic formulations is also a prevailing practice. The aim of this study was to determine the bacterial causes of external ocular infections (EOIs), antimicrobial resistance and its associated risk factors among patients at Felege Hiwot Referral Hospital, Northwest Ethiopia. Methods A hospital based cross - sectional study was conducted from 1 February to 30 April 2019. Patients with EOIs were consecutively included from 1 February to 30 April, 2019. Data were collected using structured questionnaire by face-to-face interview and complemented with patient card review. Conjunctival, eyelid margin and lacrimal sac swabs were collected aseptically. Bacterial species were identified using standard bacteriological techniques. Antimicrobial susceptibility testing was done using Kirby-Bauer disk diffusion method. Binary logistic regression analysis was calculated to identify the factors associated with EOIs. P.value (p) < < 0.05 was considered as statistically significant. Results A total of 360 patients took part in the study and majority of them were males (64.7%). The median age of study participants was 59.5 years. Overall, 208(57.8%) (95%CI = 52.6– - 62.8%) of patients had culture confirmed bacterial EOIs. The proportion of culture confirmed EOIs was 60.4% among conjunctivitis cases and 55.8% among blepharitis. Ocular trauma (P < < 0.001), ocular disease (P < < 0.001) and having eye allergy (P = 0.027) were significantly associated with EOIs. The most frequent isolates were S. aureus (37%), K. pneumoniae (13.5%), Proteus(7.2%) spp., S. pneumoniae (4.3%), Citrobacter spp. (3.4%) and P. aeruginosa (2.9%). Gram positive isolates were resistant to penicillin in 87% and ampicillin in 86.2%. Gram negative isolates were resistant to ampicillin (87.5%). P.aeruginosa isolates (85.3%) were resistant to piperacillin and 50% were resistant to tobramycin. Overall, 45.2% of the isolates were multi-drug resistant. The percentage of multi-drug resistance was 80% among Enterobacter isolates and 64.3% among K. pneumoniae. Conclusions Bacterial external ocular infections linked with multi-drug resistance and resistance to penicillin, ampicillin, tetracycline and piperacillin are high. Therefore, empirical treatment of eye infections in the study area needs to be monitored by regular antimicrobial-susceptibility testing of isolates.

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